• Title/Summary/Keyword: abnormal development

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Developing an Urban Planning Model for Climate Change Adaptation

  • Kim, Jong-Kon;Rhim, Joo-Ho;Lee, Sung-Hee
    • International conference on construction engineering and project management
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    • 2015.10a
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    • pp.51-53
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    • 2015
  • As abnormal climate phenomena occur more frequently due to climate change, damage which results from meteorological disaster increases accordingly and its scale and variety are becoming wider. This paper draws out planning and design elements and application techniques to build cities more adaptive to climate change from urban development cases in US and Europe. An urban model is suggested, that enables built environment to be more resilient to risks caused by climate change is applicable to urban development projects in practice.

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Cross Correlation based Signal Classification for Monitoring System of Abnormal Respiratory Status (상관관계 기반 신호 분류를 이용한 비정상 호흡 상태 모니터링 시스템)

  • Lee, Deokwoo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.5
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    • pp.7-13
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    • 2020
  • This paper focuses on detecting abnormal patterns of respiration of humans. In this study, a contact-based device was used to acquire both normal and abnormal respiration signals. To this end, this paper reports the development of a monitoring system to investigate the respiratory status of humans in a normal environment. This work aims to classify the respiratory status, i.e., normal and abnormal status, quantitatively. The respiration signal is acquired using a contact-based medical device (BIOBPAC), and noise reduction is carried out before classifying the respiratory status. To reduce noise, a mixed filter that combines the Savitzky-Golay filter and Median filter is applied to the acquired respiration signals. The inter-class distance is maximized, and the intra-class distance is minimized. The proposed algorithm is straightforward and can be applied to a practical environment. In addition, the experimental results are provided to substantiate the proposed approach.

RT-PCR of Up-Regulated Factors in Abnormally Proliferated Vascular Endothelial Cells by 1, 2-Dimethylhydrazine. (DMH(1,2-Dimethylhydrazine)에 의해 비정상적으로 증식된 혈관 내피세포에서 발현증가 인자들에 대한 RT-PCR의 결과)

  • Kim, Sung-Ho;Kang, Young-Seok;Bae, Yong-Chan;Park, Suk-Young;Nam, Su-Bong
    • Archives of Plastic Surgery
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    • v.32 no.6
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    • pp.689-698
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    • 2005
  • Many studies for verifying angiogenesis have been in progress, especially in the field of abnormal vascular proliferation to explain the pathogenesis and to develop a treatment of several diseases. In our previous experiments, endothelial cell proliferations were induced by DMH stimulation in vitro, and the 177 factors(142 up-regulated and 35 down-regulated factors) were identified. Among the up-regulated factors, 9 substances (EFEMP1, CTGF, CYR61, $ITG{\beta}1$, FHL2, SERPINE1, MYC, PTTG1 and MSH6) were selected, which were related to cell proliferation and showed high signal intensities. The RNA was isolated from HUVECs at the time of 0, 6, 12, 24 hours after the DMH treatment, and RNA of control group HUVECs was also isolated. Genetic information of selected molecules was used to make primer for each, and RT-PCR was performed to analyze both groups. In control and treatment groups, each substance presented variety of manifestation degree according to time differences. EFEMP1, CTGF, CYR61, $ITG{\beta}1$, FHL2 and MYC were related to abnormal vascular proliferation steadily and SERPINE1, PTTG1 and MSH6 were related secondarily. CTGF was related to both normal and abnormal proliferation, but it played a more significant role in abnormal proliferation from earlier stage. EFEMP1, CYR61, $ITG{\beta}1$, FHL2 and MYC were similar to CTGF, although the relation appeared lately. Further study should be performed to analyze the expressions and the interactions of growth factors, which could be utilized in the new therapeutic development.

Human embryos derived from first polar body nuclear transfer exhibit comparatively abnormal morphokinetics during development

  • Leila Heydari;Mohammad Ali Khalili;Azam Agha Rahimi;Fatemeh Shakeri
    • Clinical and Experimental Reproductive Medicine
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    • v.50 no.3
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    • pp.177-184
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    • 2023
  • Objective: Reconstructed oocytes after polar body genome transfer constitute a potential therapeutic option for patients with a history of embryo fragmentation and advanced maternal age. However, the rescue of genetic material from the first polar body (PB1) through introduction into the donor cytoplasm is not yet ready for clinical application. Methods: Eighty-five oocytes were obtained following in vitro maturation (IVM) and divided into two groups: PB1 nuclear transfer (PB1NT; n=54) and control (n=31). Following enucleation and PB1 genomic transfer, PB1 fusion was assessed. Subsequently, all fused oocytes underwent intracytoplasmic sperm injection (ICSI) and were cultured in an incubator under a time-lapse monitoring system to evaluate fertilization, embryonic morphokinetic parameters, and cleavage patterns. Results: Following enucleation and fusion, 77.14% of oocytes survived, and 92.59% of polar bodies (PBs) fused. However, the normal fertilization rate was lower in the PB1NT group than in the control group (56.41% vs. 92%, p=0.002). No significant differences were observed in embryo kinetics between the groups, but a significant difference was detected in embryo developmental arrest after the four-cell stage, along with abnormal cleavage division in the PB1NT group. This was followed by significant between-group differences in the implantation potential rate and euploidy status. Most embryos in the PB1NT group had at least one abnormal cleavage division (93.3%, p=0.001). Conclusion: Fresh PB1NT oocytes successfully produced normal zygotes following PB fusion and ICSI in IVM oocytes. However, this was accompanied by low efficiency in developing into cleavage embryos, along with an increase in abnormal cleavage patterns.

Deep Learning based User Anomaly Detection Performance Evaluation to prevent Ransomware (랜섬웨어 방지를 위한 딥러닝 기반의 사용자 비정상 행위 탐지 성능 평가)

  • Lee, Ye-Seul;Choi, Hyun-Jae;Shin, Dong-Myung;Lee, Jung-Jae
    • Journal of Software Assessment and Valuation
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    • v.15 no.2
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    • pp.43-50
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    • 2019
  • With the development of IT technology, computer-related crimes are rapidly increasing, and in recent years, the damage to ransomware infections is increasing rapidly at home and abroad. Conventional security solutions are not sufficient to prevent ransomware infections, and to prevent threats such as malware and ransomware that are evolving, a combination of deep learning technologies is needed to detect abnormal behavior and abnormal symptoms. In this paper, a method is proposed to detect user abnormal behavior using CNN-LSTM model and various deep learning models. Among the proposed models, CNN-LSTM model detects user abnormal behavior with 99% accuracy.

Development of an Engine Oil Quality Monitoring System (엔진오일 유전상수 변화량 측정에 의한 엔진오일 품질 모니터링 시스템 개발)

  • Chun, Sang-Myung
    • Tribology and Lubricants
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    • v.27 no.3
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    • pp.125-133
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    • 2011
  • The purpose of this study is to develop an engine oil quality monitoring system to warn the abnormal condition of engine oil. To do this, first of all, it is needed a personal controller development to measure the capacitance of a pre-developed engine oil deterioration detection sensor integrated with an oil filter. To measure the capacitance of engine oil in the sensor, it is used the way measuring the electric charging time in a capacitor by impressing DC volt. This method has merits on cost and signal stability. The measured capacitance is compensated by comparing with the one measured by an impedance analyzer. Also, using the dielectric constant gained by an impedance analyzer, the calculating equation of the dielectric constant of engine oil related with the currently developed sensor is decided. Then, the deterioration degree of engine oil is estimated according to the change rate of dielectric constant between green oil and used oil. Finally, using this dielectric constant information together with engine oil temperature and pressure, the currently developed engine oil quality monitoring system is to tell the abnormal state of engine oil.

Development of Condition Monitoring System for Reduction Unit of High-speed Rail (고속열차용 감속기 모니터링 시스템 개발)

  • Lee, Dong-Hyong;Kwon, Seok Jin;Park, Byoung-Su;Cho, Duk-Young;Kim, Jin-Woo
    • Journal of the Korean Society for Precision Engineering
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    • v.30 no.7
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    • pp.667-672
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    • 2013
  • This paper presents the development of a condition monitoring system that monitors the operating conditions of a reduction unit, such as the bearing temperature, gearbox vibration, and gear oil deterioration, and notifies the operator of potential problems or abnormal conditions. A series of field tests on high-speed rail and conventional lines was performed to identify the characteristics of temperature rise and vibration levels on the reduction unit during operation. The monitoring system was designed based on the proper sensor selection, measurement method, and signal analysis to optimize the interface with the operating system of high-speed trains. Application of this monitoring system to high-speed trains will play an important role in their proper maintenance and safe operation.

Acoustic screening test for laryngeal cancer (음성을 이용한 후두암의 집단선별검사)

  • 박헌수
    • Korean Journal of Bronchoesophagology
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    • v.7 no.2
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    • pp.161-167
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    • 2001
  • Background and Objectives: Total laryngectomy is often required for advanced cases. But this operation induced the many inconvenience of basic daily life. Early diagnosis of laryngeal cancer is very important to prevent from this disastrous condition. In this point of view, mass screening test for early detection of laryngeal cancer is necessary. Screening test using voice has many advantages such as simple, less interventional. Voice collection by Automatic Response System(ARS) is comfortable and easy to got acoustic sample. Thus author tried to got the acoustic parameters which can differentiate normal, benign. and malignant laryngeal diseases and also checked the availability of parameters on neural network system. Materials and Methods: Author has evaluated the voice from 17 laryngeal cancer patients and 45 benign laryngeal disease patients who visited at Department of Otolaryngology, Pusan National University Hospital from May 1998 to April 2001, and 15 normal control. Author chose the sir Parameters (Jitt. vFo, Shim, vAm, NHR, SPI) that was thought to be related with voice collected by ARS among thirty-three parameters analysed by a Multi-Dimensional Voice Program (MDVP). Two-step neural network was used for the availability of six parameters. Results: The detection rate of normal voice by ARS voice analysis is 78.5% and detection rate of abnormal voice was 97.1 o/o. Among abnormal voice, the detection rate of benign laryngeal diseases and laryngeal cancers were 82.4 o/o, 70.6% respectively. Conclusion: Author concluded that six parameters and Matlab based neural network software may be effective in development of acoustic screening system for laryngeal cancer and further study should be necessary for development of new acoustic parameters.

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Observation of Abnormal Waves from South in Winter (겨울철에 발생한 이상 남파 관측)

  • 김태림;전기천;박광순;김상익
    • Journal of Korean Society of Coastal and Ocean Engineers
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    • v.12 no.1
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    • pp.11-18
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    • 2000
  • On the 25th of November in 1997 winter season, unprecedented high waves were recorded at the southern part of Korea Peninsular. The significant wave heights over 4 m were recorded at Marado, Pusan and Ulrungdo successively with time lags. Seoguipo breakwaters which were under construction were damaged by the unexpected high waves. These unprecedented southerly high waves in winter seem to be caused by unusual development and traveling of low pressure. Weather charts and wave fields calculated by a numerical model were analyzed to examine the unusual development of these waves. Protection against the southerly high waves in winter must be considered in coastal constructions and structures.

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Development of Misfire Detection Using Spark-plug (스파크플러그를 이용한 실화감지에 관한 연구)

  • 채재우;이상만;정영식;최동천
    • Transactions of the Korean Society of Automotive Engineers
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    • v.5 no.1
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    • pp.27-37
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    • 1997
  • Internal combustion engine is the main source of environmental pollutants and therefore better technology is required to reduce harmful elements from the exhaust gases all over the world. Especially, harmful elements from the exhaust gases are caused by incomplete combustion of mixture inside the engine cylinder and this abnormal combustion like misfire or partial burning is the direct cause of the air pollution and engine performance degradation. the object of this research is to detect abnormal combustion like misfire and to keep the engine performance in the optimal operating state. Development of a new system therefore could be applied to a real car. To realize this, the spark-plug in a conventional ignition system is used as a misfire detection sensor and breakdown voltage is analyzed. In this research, bias voltage(about 3kV) was applied to the electrodes of spark-plug and breakdown voltage signal is obtained. This breakdown voltage signal is analyzed and found that a combustion phenomena in engine cylinder has close relationship with harmonic coefficient K which was introduced in this research. Newly developed combustion diagnostic method( breakdown voltage signal analysis) from this research can be used for the combustion diagnostic and combustion control system in an real car.

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