• 한국광학회지
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• 제18권1호
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• pp.19-23
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• 2007

원리적인 다양한 장점에도 불구하고 취급이 복잡하고 고차 연립방정식으로 표현되는 현실적 제한으로 인하여 실제 설계과정에서 잘 적용하지 않는 자이델 3차 수차를 이용하여 구한 코마수차 계수식으로부터 근사적인 제로조건을 만족하는 유한 물체거 리를 갖는 코마수차가 제거된 2반사경계의 초기설계에 유용한 곡률선형방정식을 유도하고 그 특징을 조사한다. 즉 주경과 부경의 곡률, 주경과 부경사이의 거리, 유효초점거리로 표현된 변형된 코마수차계수로부터 코마수차계수가 제거되는 조건에서 설계변수를 구하기 위해 전산수치해석 후 나온 데이터를 기반으로 주경과 부경사이의 선형관계가 나타나는 곡률선형방정식을 구하는 것이다. 이는 유한 물점의 코마수차가 보정된 2 반사경계에서 약간의 대수적인 계산만으로 최적화의 초기 입력 데이터를 손쉽게 구할 수 있는 것을 의미한다.

• 한국안광학회지
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• 제11권2호
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• pp.77-83
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• 2006

본 연구에서는 프리즘 처방을 위해 편심된 안경렌즈의 산각위치에 따른 수차와 경사각에 따른 수차를 계산하였다. 프리즘 처방을 위해서 일반적으로 일반 렌즈를 편심시켜 만든다. 광축과 주시축 사이의 차이는 수차를 발생시키기 때문에, 이런 경우 산각의 위치가 중요하다. 우리는 계산을 통하여 산각 회전 띠의 축이 (+)렌즈의 전면 곡률 중심을 지나는 것이 후면곡률 중심을 지나는 것보다 비점수차가 적게 발생하였고, 산각 회전 띠의 (-) 렌즈의 후면곡률 중심을 지나는 것이 전면보다 비점수차가 적게 발생한다는 결과를 얻었다. 렌즈의 굴절력이 클수록 비점수차가 작았다.

• Clinical and Experimental Pediatrics
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• 제55권12호
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• pp.487-490
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• 2012

We report a case of isodicentric chromosome 15 (idic(15) chromosome), the presence of which resulted in uncontrolled seizures, including epileptic spasms, tonic seizures, and global developmental delay. A 10-month-old female infant was referred to our pediatric neurology clinic because of uncontrolled seizures and global developmental delay. She had generalized tonic-clonic seizures since 7 months of age. At referral, she could not control her head and presented with generalized hypotonia. Her brain magnetic resonance imaging scans and metabolic evaluation results were normal. Routine karyotyping indicated the presence of a supernumerary marker chromosome of unknown origin (47, XX +mar). An array-comparative genomic hybridization (CGH) analysis revealed amplification from 15q11.1 to 15q13.1. Subsequent fluorescence in situ hybridization analysis confirmed a idic(15) chromosome. Array-CGH analysis has the advantage in determining the unknown origin of a supernumerary marker chromosome, and could be a useful method for the genetic diagnosis of epilepsy syndromes associated with various chromosomal aberrations.

• The Korean Journal of Physiology
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• 제19권2호
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• pp.189-202
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• 1985

Enhanced activity of renin-angiotensin-aldosterone system has been suggested as a cause of the high blood pressure in certain forms of experimental hypertension. In spontaneously hypertensive rats, however, increased activity of the system has not been found, and even suppressed renin angiotensin system has been reported in the spontaneously hypertensive rat. In the present experiments it was attempted to explore the possible alteration of the short loop negative feedback control in the hypertensive rat. Experiments have been done in the anesthetized spontaneously hypertensive rats(SHR) as well as in normotensive Wistar and Sprague Dawley rats as control. Responses of the plasma renin activity to the intravenous L-isoproterenol were dose dependent, in both SHR and normotensive control rats. Hypotensive responses to smaller do sea of L-isoproterenol were more accentuated in SHR than in the normotensive control rats. Angiotensin If given intravenously suppressed plasma renin activity in a dose dependent fashion in both groups. However, these suppressive responses were significantly attenuated in SHR as compared with the normotensive control rats. Treatment with angiotensin I-converting enzyme inhibitor did not correct the attenuated responses of the plasma renin activity to angiotensin II in SHR. Intravenous infusion of arginine vasopressin also produced a dose-dependent suppression of plasma renin activity in both groups. The responses to arginine vasopressin were also significantly attenuated to the normotensive control rats. In the sodium-depleted SHR, arginine vasopressin did not suppress plasma renin activity, whereas the suppressive responses to arginine vasopressin in the normotensive control rats were not different from the untreated control rats. These data suggest that there may be a derangement in the short loop negative feedback control of the renin-angiotensin system in spontaneously hypertensive rat.

• 반도체디스플레이기술학회지
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• 제15권3호
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• pp.62-66
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• 2016

Optical system needs to be aligned before its undergoing process, is usually shows coma aberrations, which occurred due to imperfection in the lens or other components results in off-axis point sources, appearing to have a tail like a comet. There are some methods to correct coma aberration. In this paper, to correct coma aberration in optical system, using a robot arm type coordinate measuring machine(CMM). CMMs are widely used to measure the form of accuracy of parts and positioning accuracy of systems. Among them, robot arm type CMM has more advantages than the others, such as its mobility and measuring range. However, robot arm type CMM has lower accuracy than cantilever type CMM. To prove robot arm type CMM's accuracy, several factors were suggested in this paper and the final measuring results were compared to a commercial cantilever type CMM. Based on this accuracy, a typical optical system was successfully aligned by using our robot arm type CMM.

• 한국광학회지
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• 제16권1호
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• pp.34-42
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• 2005

본 논문은 3군 구성의 줌 광학계에 대해 렌즈모듈의 개념을 이용하여 1차량 및 3차 수차를 고려한 최적의 초기설계와 이로부터 실제 줌 광학계를 설계하는 방법을 제안 하였다. 각각의 렌즈모듈에 적절히 1차량과 3차 수차량을 설정함으로써 줌비 2배(f = 4.3∼8.6 mm)를 갖고, 시스템에서 요구하는 구속조건을 만족시키는 초기설계 줌 광학계를 얻었다. 각 군의 역할에 따라 적절히 선정된 각각의 렌즈군의 초점거리 및 1차량이 렌즈모듈의 값과 같도록 독립적으로 설계한 후, 군사이의 공기간격을 조정하므로써 줌궤적을 일치시켰다. 이러한 과정을 통해 설계된 줌 광학계는 렌즈모듈로 구성된 원래의 초기 설계된 줌 광학계와 동일한 1차 특성을 갖는다. 결과적으로 잔여수차 보정을 통해 후군초점조절방식을 이용하는 컴팩트 디지털 카메라 및 모바일 폰용 줌 렌즈로서 유용한 줌 광학계를 얻을 수 있었다.

• 한국광학회지
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• 제17권2호
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• pp.113-119
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• 2006

망막검사를 위한 검안경용 망막 카메라를 개발하기 위한 광학계 설계를 연구하였다. 이에 앞서 사람의 눈에 대한 광학계 제원은 김상기와 박성찬이 발표한 정밀모형안을 채택하였다. 이를 토대로 하여 광학계를 4개의 렌즈 군으로 구성하였고 제 1군으로 모든 시야각에 대한 광을 중심으로 모았다가 제2, 제3, 제4군에 의해 결상하도록 하였다. 결상된 망막의 상은 CCD 광검출기에 의해 모니터로 전시한다. 제 1군을 단일 렌즈로 하고 나머지 광학계를 triplet로 하여 최적화를 통해 설계하였다. 광선수차, spot diagram, 회절을 고려한 point spread function 및 MTF를 계산하여 분석한 결과, 좋은 성능을 가진 광학계 설계가 가능하였다. 본 연구 결과에서 얻은 광학계로서 양질의 망막 카메라를 개발할 순 있을 것으로 믿는다.

• Journal of Genetic Medicine
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• 제13권2호
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• pp.95-98
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• 2016

We report the prenatal diagnosis of an unbalanced translocation between chromosome Y and chromosome 15 in a female fetus. Cytogenetic analysis of parental chromosomes revealed that the mother had a normal 46,XX karyotype, whereas the father exhibited a 46,XY,der(15)t(Y;15) karyotype. We performed cytogenetic analysis of the father's family as a result of the father and confirmed the same karyotype in his mother and brother. Fluorescence in situ hybridization and quantitative fluorescent-polymerase chain reaction analysis identified the breakpoint and demonstrated the absence of the SRY gene in female members. Thus, the proband inherited this translocation from the father and grandmother. This makes the prediction of the fetal phenotype possible through assessing the grandmother. Therefore, we suggest that conventional cytogenetic and molecular cytogenetic methods, in combination with family history, provide informative results for prenatal diagnosis and prenatal genetic counseling.

• Restorative Dentistry and Endodontics
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• 제25권1호
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• pp.78-84
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• 2000

The aim of this study was to compare shaping ability of nickel-titanium rotary files with different taper in simulated resin canals. The instruments used in this study were GT with .04 taper ProFile with ISO-sized tip, .04 taper ProFile with ISO-sized tip alone, and .02 taper Naviflex file and all canals were prepared by crown-down technique. A total of 30 composite images were made from pre- and post-canal scanned images using Scanjet 4C scanner and Corel photopaint 8.0 and then, prevalence of canal aberrations was measured. The amount of coronal substance the instruments removed was also calculated two-dimensionally on digitized images with the Brain C software to compare the relative enlarging efficiency. Finally, the prepared internal canal form was evaluated three-dimensionally with impression technique. The results were as follows; 1. The incidence of zipping in Naviflex group was significantly high compared to the other two groups(P<.05). 2. The amount of coronal substance the GT combined group removed was significantly larger than the other two groups(P<.05). 3. The GT combined group produced canals with good taper and flow. Under the conditionas of this study, the combined use of larger tapered nickel-titanium rotary files prepared simulated canals safely, efficiently and with good three-dimensional form.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2007년도 하계학술대회 논문집 Vol.8
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• pp.57-57
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• 2007

Aspheric glass lenses have many optical advantages, for glass have superior optical performance and an aspheric form can reduce optical aberrations. Recently, the use of it is rapidly expanding as the mass production becomes possible by glass molding press and so this method is considered as the best method for fabricating an aspheric glass lens, but it is difficult to control many parameters for pressing and cooling process. Design of experiments (DOE) is a very useful tool to design and analyze complicated industrial design problems. This study investigated the pressing conditions to mold aspheric glass lenses for mega pixel phone camera module using DOE method. We have applied fractional factorial design and the response variable was set form accuracy (PV) of aspheric surface of molded lens. The results of analysis indicates that all factors expect for pressing force of each step are available for the form accuracy (PV). It was the optimum condition of the designed pressing conditions for lowering the form accuracy(PV) value of molded lens that all factors were at the low level. The form accuracy (PV) of mold and molded lens under the optimum condition are $0.85\;{\mu}m$ and $0.922\;{\mu}m$ respectively.