• Asian-Australasian Journal of Animal Sciences
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• 제20권10호
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• pp.1503-1509
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• 2007

Endothelin-1 (ET-1) is an important factor in regulation of cardiovascular tone in humans and mammals, but the biological function of ET-1 in the avian vascular system has not been determined. The purpose of this study was to characterize the role of endogenous ET-1 in the vascular system of poultry by investigating the effect of endothelin A receptor ($ET_AR$) antagonist BQ123 on the femoral artery pressure (FAP) and the pulmonary artery pressure (PAP) in broiler chickens. First, we found that plasma and lung homogenate ET-1 levels were both increased with age over the seven weeks life cyccle of broiler chickens. Second, 60 min after intravenous injection, BQ123 ($0.4{\mu}g\;kg^{-1}$ and $2.0{\mu}g\;kg^{-1}$, respectively) induced a significant reduction in FAP and PAP (p<0.05). Third, chronic infusion of BQ123 ($2.0{\mu}g\;kg^{-1}$ each time, two times a day) into abdominal cavities led to significant decrease in systolic pressure of the femoral (p<0.05) and pulmonary arteries (p<0.01) in broiler chickens at 7 and 14 days after treatment. Taken together, the $ET_AR$ antagonist BQ123 lead to a significant reduction of FAP and PAP, which suggests that endogenous ET-1 may be involved in the maintenance and regulation of systemic and pulmonary pressure in broiler chickens.

• 한국의류산업학회지
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• 제18권1호
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• pp.80-90
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• 2016

This study presents quantitative evaluation standards for they mobility test, conducted in the process of a slacks fit test. This study quantified the subjects' evaluation on the wearability of slacks to provide objective qualitative evaluation methods for existing mobility tests. The subjects were women of standard bodytype between the ages of 18 and 24 wearing slacks designed to test their mobility based on differences in ease in waist girth, hip girth, crotch length and knee length. A qualitative evaluation tested the wearability of slacks. Clothing pressure and gap area between the body and slacks were measured based on a quantitative evaluation. The clothing pressure and the gap area between the body and slacks (which reflect the results of the wearability test) were presented in this study as quantitative evaluation standards. Clothing pressure tended to increase as the ease of slacks decreased; however, clothing pressure standards, that induce discomfort, differed by body parts. The hip, crotch, and knee area were relatively less sensitive despite the waist and the abdominal area sensitivity to clothing pressure. This study suggests the minimum ease for the appropriate wearing comfort of slacks by region and motion as standards for the quantitative evaluation of mobility tests. These was reset in accordance to the limits of clothing pressure when the minimum ease was considered as wearable but exceeded the clothing pressure limits.

• 대한한의학회지
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• 제35권1호
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• pp.135-144
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• 2014

Objectives: The purpose of this study is to evaluate the effects of Metabolic Syndrome care program with Korean Medicine in public health center. Methods: The data were collected from 28 participations who joined Korean Medicine care program. The program was started from April of 2013 and finished November of 2013. The effect of Metabolic Syndrome were evaluated with blood pressure check and blood test, physical test. Results: The number of Metabolic Syndrome patients decreased after the program(-24.9%). Specially TG decreased from 83.321 to 80.036(p<0.05) and FBS also decreased 8.607(p<0.01) after the program. HDL increased from 47.821 to 53.000(p<0.01) but blood pressure didn't change. BMI decreased 0.789(p<0.01) and abdominal obesity decreased 2.607(p<0.01) after the program significantly. Conclusions: From these study, the Metabolic Syndrome care program with Korean Medicine is worthy for treating Metabolic Syndrome.

• 혜화의학회지
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• 제19권2호
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• pp.173-177
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• 2011

We treated a 45 year-old male patient. He had Hypertension, Diabetes, Hyperlipidemia and Obesity. The main symptoms were Low-back pain, General body weakness, Abdominal discomfort. We diagnosed him as metabolic syndrome and prescribe Yagwanchunghyul-tang three times a day. We observed clinical symptoms Blood pressure, Capillary blood glucose, BMI, Body weight. Cholesterol, Triglyceride. After the treatment, The main symptom, blood pressure, capillary blood glucose(PP2hr), Hypercholesterol, Hypertriglyceride were improved. and BMI levels fell. This case shows that Yagwanchunghyul-tang has an effect on Metabolic syndrome like a Hypertension, Diabetes, Hyperlipidermia, Hypertriglyceride.

• Journal of Chest Surgery
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• 제25권2호
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• pp.200-204
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• 1992

A 63 year old male had suffered from hypertension and angina pectoris for 4 years, On physical examination, blood pressure was 150/110 mmHg with medication of antihypertensive drugs. Aortogram showed the stenosis of the left renal artery, the complete occlusion of the right renal artery, and atherosclerotic change of abdominal aorta. Blood urea nitrogen was 25 mg/dl, serum creatinine was 1.2 mg/dl, and renin activity in peripheral blood was 8.7 ng /ml /hour, The stenosis of left renal artery and the complete occlusion of right renal artery should have produced the renovascular hypertension Bilateral aorto-renal bypasses with saphenous grafts were done for treatment of ren-ovascular hypertension Postoperatively, blood pressure was normalized with only small dosage of antihypertensive drugs.

• 한국정보통신학회논문지
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• 제20권6호
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• pp.1074-1080
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• 2016

빅데이터 분석은 기존 데이터베이스 관리 도구로부터 데이터를 수집, 저장, 관리, 분석할 수 있는 역량을 말한다. 따라서 메타분석은 여러 실증연구의 정량적인 결과를 통합과 분석을 통해 전체 결과를 조망할 수 있는 기회를 제공하는 통계적 통합 방법이다. 일반적으로 대사증후군 위험요인을 허리둘레, 수축기혈압, 이완기혈압, 공복혈당, 중성지방 그리고 고밀도지단백콜레스테롤 요인으로 정의한다. 메타분석 결과 공복혈당 사전 사후 경로에서 가장 큰 효과크기(r = -.324)인 것으로 나타났다. 따라서 콩 식품의 중재효과는 10%의 설명력을 확인할 수 있었다. 두 번째 큰 효과크기는 허리둘레 사전 사후 경로(r = .256)인 것으로 나타났다. 그런데 콩 식품의 습취는 허리둘레 (복부비만) 개선효과가 없는 것을 확인할 수 있었다. 이러한 결과를 바탕으로 학문적 실무적 의의를 논의하였다.

• Journal of Nutrition and Health
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• 제42권3호
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• pp.234-245
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• 2009

Nutritional assessment for the elderly can identify health status and morbidity. However, development of Nutritional Risk Index (NRI) remains limited for elderly because of difficulties in understanding physiological mechanism of elderly. This study was performed to analyze and develop Nutritional Risk Index for Korean elderly Women (Geriatric Nutritional Risk Index, GNRI). Based on literature review, factors for NRI were identified and indices were assessed by a cross-sectional survey. The survey involved Korean elderly women (${\geq}$60, n = 94) in Gwangju area, and sociodemographics, lifestyle characteristics, health conditions, dietary intakes based on 24h- recall, anthropometric measures (wt, ht, BMI, waist, hip, WHR, body protein, body fat, abdominal fat, and triceps skinfold thickness), and clinical biochemistry parameters (systolic blood pressure, diastolic blood pressure, cholesterol, HDL-cholesterol, triglyceride, total protein, albumin, prealbumin, hemoglobin, hematocrit, fasting blood glucose, HbAlc, ferritin, Zn, Ca, Na, K, Vit E, Vit $B_{12}$, folate, C-reactive protein) were examined relation to nutritional risk index. Based on literature review and data analyses, three NRIs were categorized (NRI I, NRI II, NRI III) and used for further analysis. NRI I was related to having metabolic syndrome, NRI II was related to serum albumin and body weight, and NRI III was related to food habit and health concerns. Abdominal fat (%) of elderly was correlated with each NRIs. NRI II was correlated with nutritional deficiency and higher tendency of inflammatory response, and NRI III was correlated with nutritional status which tend to be lower on aging (protein, folate, Vit $B_{12}$). NRI can serve as a useful tools in assessing health risk and nutritional status. Some modification of items in NRI and validity study are need to apply to Korean elderly.

• 한국임상수의학회지
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• 제32권1호
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• pp.101-104
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• 2015

4년령의 수컷 골든 리트리버 견이 복부 팽만 및 호흡곤란을 주증상으로 내원하였으며, 신체 검사 결과 부정맥과 심잡음이 청진되었다. 흉복부 방사선 검사 결과 전반적인 심비대, 흉수 및 복수가 관찰되었다. 심초음파 검사에서 비정상적인 승모판 및 삼첨판의 움직임과 역류가 관찰되었으며, 좌심실의 편심성 비대와 좌심방 비대가 보였다. 컬러 도플러 영상에서 확장기에 승모판 입구로부터 좌심실로 유입되는 와류가 관찰되었으며, 수축기에는 좌심방 및 우심방으로의 와류가 보였다. 도플러 검사로 확장기 승모판 유입 속도가 매우 증가하였으며 pressure half time이 지연되었다는 것을 알 수 있었다. 심초음파 검사 결과에 기초하여 승모판 협착증과 병발된 승모판 이형성증과 삼첨판 이형성증을 진단하였다.

• 대한지역사회영양학회지
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• 제22권6호
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• pp.507-519
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• 2017

Objectives: The objective of this study was to examine the relations between total vegetable and Kimchi intakes and the risk of metabolic syndrome (Mets) in Korean adults. Methods: This study used dietary intake and health data of 6668 subjects aged 20 years and over from the 2010-2011 Korea National Health and Nutrition Examination Survey (KNHANES). Daily intakes of total vegetables and Kimchi were assessed by 24-hour recall data. The odds ratio of Mets risk according to daily intake of vegetables and Kimchi was analyzed, respectively. Results: The highest consumption of total vegetables was associated with a lower risk of abdominal obesity (multivariable adjusted OR=0.56, 95% CI: 0.33, 0.93) in men and lower risk of Mets (multivariable adjusted OR=0.67, 95% CI: 0.47, 0.94) in women. Kimchi consumption was not related to the risk of Mets in both men and in women. However, a higher intake of Kimchi was associated with an increased risk of elevated blood pressure (Q1 vs Q5, multivariable adjusted OR=1.34, 95% CI: 0.95, 1.90, P for trend= 0.0261) in women. Conclusions: A higher intake of vegetables was associated with decreased risk of abdominal obesity and Mets in both men and women, respectively. A higher consumption of Kimchi was not related to the risk of Mets in both in men and in women. However, a higher intake of Kimchi was associated with an increased risk of elevated blood pressure in women.

• 사상체질의학회지
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• 제32권2호
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• pp.48-60
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• 2020

Objective The purpose of this study is to study the effects of Taeeumjowi-tang extract granule on metabolic syndrome with obesity in Taeeumin. Methods We studied 206 subjects who diagnosed metabolic syndrome with obesity and classified Taeeumin by a Sasang constitution analysis tool. The subjects were administered by Taeeumjowi-tang for 12 weeks. We investigated the changes of body mass index, abdominal circumference, the number of risk factors for metabolic syndrome, lipid, fasting blood sugar, Hemoglobin A1c, free fatty acid, insulin, and blood pressure. Results Body mass index and abdominal circumference, systolic and diastolic blood pressure were significantly reduced after 4 weeks, 8 weeks, and 12 weeks of administration compared to before administration. Triglyceride significantly decreased after 8 weeks and 12 weeks of dosing compared to before taking. Low density lipoprotein cholesterol, fasting blood sugar were significantly increased after 8 weeks of administration compared to before administration. High density lipoprotein cholessterol was decreased significantly after 4 weeks of administration compared to before administration. The number of risk factors for metabolic syndrome, Hemoglobin A1c increased significantly after 12 weeks of administration compared to screening. Conclusions In this study we knew that Taeeumjowi-tang extract granule is very efficient in metabolic syndrome, especially in obesity and hypertension, triglyceride, insulin resistance.