• 복식문화연구
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• 제28권6호
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• pp.771-786
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• 2020

This study aims to develop a life-friendly, wrap-one-piece style dance sports practice wear considering the physical characteristics of middle-aged, abdominally obese women. These types of practice wear allow people to enjoy exercise easily and to wear these garments as daily wear while meeting the requirements for dance sports wear. The three participants selected for this study were all women with five or more years of dance sports experience and were all average sized on Korea's abdominal obesity scale. In the first phase of the study, practice wear was created in a total of nine styles with three different styles of neckline depths for three different styles of dress skirt lengths. In the second phase of the study, the practice wear was created in 15 styles with five different styles of sleeve lengths for three different styles of waistline heights. After analyzing the design preferences of the participants, the fit preferences of the designs were evaluated and the final appearance was analyzed in order to suggest a pattern. The results of the subjects' first and second preference evaluations showed a preference for a 10 centimeter neckline depth, for high waistlines, and for elbow to wrist-length sleeves. The implementation of this research is expected to be extensive, as its results can be used as basic data for making lifestyle dance sports practice wear that covers the physical insecurities of middle-aged, abdominally obese women and enables them to enjoy their leisure time.

• 대한한방내과학회지
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• 제43권4호
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• pp.606-624
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• 2022

Objective: The aim of this study was to compare the effects of different doses of Geumnyeonyijin-tang (GNYJT) water extracts with those of metformin (250 mg/kg) in mild diabetic-obese mice. Methods and Results: The 48 mice were divided into 1 normal pellet diet (NFD) group and 5 high-fat diet (HFD) groups. At the end of 12 weeks of oral administration of metformin (250 mg/kg) or GNYJT water extracts (400, 200, or100 mg/kg), the effects were evaluated. The HFD control mice showed noticeable increases in body weight, adipose tissue density, fat pad weight of the periovarian and abdominal wall, and insulin, blood glucose, and HbA1c levels, with decreases in serum HDL levels. Increases in the periovarian and dorsal abdominal fat pad, regions of steatohepatitis, adipocyte hypertrophy, and hepatocyte hypertrophy were also discovered. The HFD group showed a decline in glucose levels and elevation of hepatic gluconeogenesis, suggesting an HFD-induced AMPK downregulation related to glucose dysregulation, as well as lipid metabolism related to obese insulin-resistant type II diabetes, dyslipidemia, and oxidative stress related diabetic hepatopathy (non-alcoholic fatty liver disease, NAFLD). Conclusion: Assessment of the key parameters for inhibition of diabetes and related complications in HFD-fed diabetic-obese mice demonstrated that GNYJT water extracts have favorable ameliorating effects. The effect of GNYJT was manifested through the stimulation of AMPK upregulation of related hepatic glucose enzyme activities and expression of lipid metabolism-related genes. Therefore, appropriate oral dosages of GNYJT could be promising as a new preventive candidate for controlling diabetes and related complications. Further screening of biologically active compounds, elucidation of detailed mechanisms, and more animal studies are warranted.

• 한국의류산업학회지
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• 제12권4호
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• pp.487-493
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• 2010

The objectives of this study were to investigate the progress of obesity in women from childhood to adulthood and to analyze the characteristics of obese figures through comparing their body proportions to normal-weight people, to provide a basic reference for development of new size categories and improved pattern grading. Body measurement was made on 6,704 women age between 7-39 in Sizekorea 2004 database. The age range was divided into three groups: children(7-12), teenagers(13-18) and adults(19-39). The result of research into the characteristics of body proportions of obese figures and the classification of different figure groups of obese people are as follows: The ratio between width and circumference for each part of the body was investigated according to body weight which was grouped into three different weights of low, normal and obese body weights. And the result demonstrated that in all the ranges of age, the obese groups had the lowest ratio between width and circumference, having a thick body shape. And according to the result of comparing the ratio of the circumference of each body part divided by the waist circumference, the obese group also showed a low ratio, indicating that they have bigger waist circumference than any other body parts. By analyzing the ratio of circumference of body parts divided by waist circumference, three factors were identified as contributing to obesity. Using the factor loadings of the upper, distal and lower body obesity, a cluster analysis was carried out and three different categories of obesity were defined; abdominal obesity, distal obesity and proximal obesity.

• 대한의생명과학회지
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• 제24권1호
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• pp.23-29
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• 2018

Abdominal obesity is considered as one of the most risky factors governing the development of metabolic diseases. Here we identify that human chitinase 3-like 1 (CHI3L1, also called YKL-40 in human) single nucleotide polymorphism (SNP), rs883125, is associated with abdominal obesity in Korean women. Korean women subjects with the rs883125 G/G or C/G genotype present higher waist-hip ratio than subjects with C/C genotype suggesting that human subjects who G nucleotide substitution at the rs883125 tended to more accumulate intra-abdominal fat at the abdominal cavity. In addition, Chi3l1 gene expression is increased in adipose tissue from obese mice and pro-inflammatory cytokine enhances Chi3l1 expression in adipocytes, indicating that Chi3l1 is greatly related with obesity and obesity-induced pro-inflammatory responses. Taken together, the minor allele of rs883125 is associated with a higher prevalence of abdominal obesity in Korean women. These findings suggest that genotype of rs883125 can be a biomarker of incident abdominal obesity and abdominal obesity-related metabolic diseases.

• Clinical and Experimental Pediatrics
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• 제48권10호
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• pp.1082-1089
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• 2005

목 적 : 복부 비만은 고혈압, 인슐린 저항, 고인슐린혈증, 당뇨, 고지혈증과 같은 많은 심혈관계 질환의 위험 요인으로 제시되고 있다. 복부 비만을 측정하는 지표로 허리/둔부 비와 허리둘레가 사용되고 있으나, 관상동맥 질환의 예측인자로 복부 비만의 측정학적 cut-off 수치가 소아에서는 아직 제시되지 못하고 있다. 복부 전산화 단층촬영과 초음파를 이용하여 복부 지방을 측정하고, 여러 비만 지표들과의 상관관계를 연구함으로써 복부 비만의 합병증으로 초래되는 심혈관계 질환의 위험인자 평가 방법을 알아 보고자 본 연구를 실시하였다. 방 법 : 비만한 청소년 27명과 나이와 성별이 대등한 정상 체중을 가진 청소년 22명을 대상으로 하여 체질량 지수와 비만 지수, 상완둘레 및 삼각근에서 피부 두께를 비교하였다. 또한, 12시간 공복 상태에서 혈중 지질 및 혈당, 인슐린, 4가지 사이토카인을 측정하고, 인슐린 저항 지수를 구하였으며, 생체 전기저항법을 이용하여 체지방량, 체지방률, 복부지방률을 측정하여 비교하였다. 비만군에서는 복부 초음파로 배꼽부위 피하지방 두께와 복강 내 지방 두께를 측정하고, 복부 전산화 단층 촬영으로 얻은 횡단면 스캔에서 전체 지방 면적을 구하였고, 이 중 피하지방의 면적을 감산하여 복강 내 지방 면적을 구하였다. 결 과 : 소아에서 복부 CT로 측정한 총 지방 면적과 생체 전기 저항법으로 측정한 총지방량과 상관성이 매우 높았다(r=0.954, P<0.05). 복부 CT에서 측정한 복강 내 지방 면적은 상완둘레, 복부비만율, 초음파로 측정한 복부 내 지방 깊이 및 피하 지방량, 체질량 지수, 중성지방 등과 상관성이 높았다. 결 론 : 복부 CT는 복강 내 지방을 측정하는 가장 정확한 방법이지만 임상적으로 유용하지 못하므로, CT와 상관성이 높은 복부 초음파로 대치할 수 있다. 외래나 학교 신체검사에서 사용할 수 있는 선별 검사로는 생체 전기 저항법에 의한 체지방 측정, 상완 둘레, 체질량 지수, 허리/둔부 비 등이 있다. 소아 성인병의 심혈관 위험 예측 지표로는 공복시 leptin, 중성지방, 인슐린 농도 등을 사용할 수 있다.

• 한방재활의학과학회지
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• 제26권1호
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• pp.13-31
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• 2016

Objectives In this study, it was investigated whether Gami-Handayeolso-Tang (HDYST) medication has anti-obesity effects in high fat diet (HFD)-fed obese mice. Methods The experimental animals were divided into five groups-normal diet-fed (ND), high fat diet-fed control (HFD), HFD+HDYST 150, HFD+HDYST 300, and HFD+orlistat as a positive drug. The obese markers such as body weight, diet efficiency ratio, serum levels of total cholesterol, triglyceride, lipid contents, leptin, adiponectin, and GOT/GPT were measured. Also, white adipose tissue, liver weight, abdominal fat mass, hepatic lipid contents, and mRNA expression of obese-associating genes were examined in obese mice. Results In high fat diet-fed mice, HDYST administration significantly decreased body weight, diet efficiency ratio, serum levels of total cholesterol, triglyceride, LDL-cholesterol, as well as leptin and GOT/GPT, compared to the HFD group in a dose-dependent manner. HDYST increased significantly the serum levels of HDL-cholesterol and adiponectin. It also reduced the accumulation of lipids, such as total lipid and triglycerides, in organs such as liver and abdominal adipose tissue. Moreover, HDYST administration significantly decreased the expression levels of fatty acid synthetic genes, such as sterol regulatory element-binding protein-1c (SREBP-1c), FAS and Stearoyl-Coenzyme A desaturase 1 (SCD-1), in the liver tissues, while it increased the messenger RAN (mRNA) levels of fatty acid catalytic genes, such as Peroxisome proliferator activated receptor alpha (PPAR-${\alpha}$), acyl-COA oxidase (ACO), and Carnitine palmitoyltransferase-1a (CPT-1a). Conclusions Based on the results above, HDYST reveals anti-obesity effects declining body fat accumulation through the regulation of fatty acid metabolism and leptin/adiponectin serum levels. It therefore suggests that HDYST can be clinically useful for the treatment of obesity.

• Journal of Applied Biological Chemistry
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• 제64권3호
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• pp.291-298
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• 2021

본 연구에서는 고지방식이(HFD)를 급식하여 제조한 비만마우스 모델을 사용하여 berberine (BBR)과 silibinin (SBN) 복합투여가 혈중 지질대사 및 항비만 개선 효능에 유의적인 시너지 효과가 있는지 조사하였다. HFD로 유도된 비만마우스를 8 주 동안 HFD의 지속적인 제공와 함께 BBR 및 SBN (BBR-SBN) 조합을 투여하였다. 실험이 진행되는 동안 체중과 식이량을 측정하였고 혈중 총 콜레스테롤, 중성지방 및 HDL 콜레스테롤 수준을 분석하였다. HFD를 제공한 마우스는 정상 대조군(NC) 그룹에 비해 체중과 총 콜레스테롤 및 중성지방 수치가 급격히 증가했다. 그러나 이러한 비만마우스에 BBR-SBN조합을 투여하였을 때 체중 증가가 현저하게 감소하였고 HDL 콜레스테롤 수치가 증가하였으며 총 콜레스테롤 및 중성지방 수치는 유의하게 억제되었다. HFD그룹의 복부지방 무게는 유의하게 증가했으며 부고환 지방조직 내의 지방세포의 크기가 NC 그룹에 비해 크게 확장된 것으로 나타났다. 그러나 BBR-SBN 그룹에서는 지방세포의 크기가 NC 그룹의 크기와 비슷했으며 복부지방 무게가 현저하게 감소하였다. 더불어, HFD 그룹에서 보이는 간 조직의 거대 소포성 지방구의 축적은 BBR-SBN 그룹에서 크게 감소되었다. 이러한 결과는 BBR-SBN 조합이 HFD 유발 비만마우스에서 체중 및 복부 지방 증가를 현저하게 감소시키는 경향이 있으며 혈청 내의 총 콜레스테롤 및 중성지방 수준을 낮추어 항비만 효능을 개선시킬 수 있는 가능성을 보여주는 것으로 앞으로 항비만 치료 및 개선제제로서의 잠재력을 가지고 있음을 시사한다.

• 한국보건간호학회지
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• 제26권3호
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• pp.417-427
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• 2012

Purpose: The purpose of this study was to examine the effect of a 12-week combined exercise training program on the body composition, physical fitness levels, and metabolic syndrome profiles of obese women. Methods: Twelve obese women were assigned to the combined exercise training program group. The women underwent training for 70-90 min/d, three times per week for a period of 12 weeks. Paired samples t-tests were performed using SPSS ver. 17.0 for analysis of the results. Results: The results of this study showed that body-composition parameters such as weight, fat-free mass, body fat mass, body-mass index, body fat, waist-hip ratio, basal metabolic rate, and intra-abdominal fat, physical fitness parameters such as muscle strength, muscle endurance, flexibility, and cardiac endurance, and metabolic syndrome biomarkers such as triglyceride levels, high-density lipoprotein cholesterol levels, glucose levels, systolic blood pressure, and waist circumference before participation the training program differed significantly from those after participation in the training program (p<0.05). However, diastolic blood pressure before participation in the training program did not differ significantly from that after participation in the training program (p>0.05). Conclusion: We concluded that a 12-week combined exercise training program could be a good exercise program for improvement of the body composition, physical fitness levels, and metabolic syndrome profiles of obese women.

• 복식문화연구
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• 제25권4호
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• pp.476-487
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• 2017

The purpose of this study was to suggest torso patterns that fit the three main body shapes of elderly obese women. To reduce time, costs, and also the trial and error needed to make patterns, the CLO program for 3D test wear was employed. Three virtual models for aged obese women were use, with the YUKA system used to produce torso patterns. 3D simulation of test wear and corrections was done to design optimal torso patterns. The results were as follows: First, for the three models of obese women's body shapes as realized by CLO 3D, Type 1 is lower-body obesity shapes, Type 2 is abdominal obesity shapes, and Type 3 is whole-body obesity shapes. Second, to design the study patterns, actual measurement values, back waist length and waist to hip length, were used. The armhole depth (B/4-1.5), front interscye (B/6+2.3), front neck width (B/12-0.5), front neck depth (B/12+0.5), front waist measurement (W/4+ 1.5+D), front hip measurement (H/4+2+0.5), and back hip measurement (H/4+3-0.5) were calculated using formulas. Third, according to the results of test-wearing the study patterns, reduced front neck width and depth improved the neck fit and reduced armhole depth bettered loose or plunging armhole girth and also reduced the sagging of bust c.. Also, tight sidesfrom aprotruded waist and abdomen improved with the increase of surpluses in the back waist and also back and front hip c. The exterior was enhanced by displacement of back and front darts, which distributed surpluses better.

• 대한한방내과학회지
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• 제43권3호
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• pp.413-422
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• 2022

Objectives: To investigate the weight loss effect of Gambi-tang in obese and overweight adults. Methods: From September 1, 2016 to December 31, 2021, a retrospective chart analysis was conducted on adult men and women who were prescribed Gambi-tang to address obesity and overweight in the National Medical Center (NMC). Partial analysis by age, obesity (Body Mass Index, BMI), duration of dose, and cumulative dose was also conducted. Results: The weight and BMI of the study subjects showed a significant decrease of more than 5% on average before and after treatment. In an analysis of age, significant differences by age could not be confirmed. In the analysis by obesity level, the effect of reducing weight, body fat, and abdominal fat rates in the obese and highly obese groups was greater than in the normal and overweight groups. There was no significant difference by group in the analysis by dosage period. In the analysis by cumulative dose, the greater the cumulative dose up to 1,800 g, the greater the decrease in weight and body fat. The side effect that patients appealed to the most was misjudgment, but not to a serious extent. Conclusions: Gambi-tang has been shown to be effective in weight and body fat loss for both obese and overweight adult men and women.