• 한방재활의학과학회지
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• 제21권2호
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• pp.279-288
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• 2011

Objectives : Our purpose of this study was to evaluate the association between abdominal adipose tissue and oriental obesity pattern identification. Methods : This study was performed in 78 healthy obese(BMI(body mass index)${\geq}25kg/m^2$) women in Seoul. Subjects underwent abdominal CT(computed tomography) scanning and were asked to complete the oriental obesity pattern identification questionnaire. Subjects were given written consent and this study was performed under permission of institutional review board of Kyung-hee East-west Neo medical center. Results : 1. VFA(visceral fat area) and VSR(visceral/subcutaneous adipose tissue ratio) were significantly correlated with stagnation of the liver qi(肝鬱, gan-yu)(p<0.05). But, other patterns were not significantly correlated with oriental obesity pattern identification(p>0.05). 2. We evaluated a difference of oriental obesity pattern identification score in visceral obesity group(n=34) versus non-visceral obesity group(n=44). Scores of all patterns except food accumulation(食積, shi-ji) were significantly higher in the visceral obesity group than in the non-visceral obesity group(p<0.05). Especially, there was a further significant difference in stagnation of the liver qi(肝鬱, gan-yu)(p<0.01). Conclusions : Generally, the stagnation of the liver qi(肝鬱, gan-yu) has a close relation with stress and depression. This study suggests that stress and depression might be correlated with visceral fat, and the use of oriental obesity pattern identification would be helpful for planning a treatment schedule of visceral obesity in the clinic.

• 대한영양사협회학술지
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• 제10권2호
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• pp.174-183
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• 2004

This analysis was performed to investigate the relationship between nutrition and anthropometric indices using the data from a cross-sectional survey of a large national sample, '98 Korean national health and nutrition examination survey. Subjects were selected by stratified multistage probability sampling design and completed dietary questionnares including food intakes for one day by 24-hour recall method. For this analysis, 6566 subjects were selected by age(over 20 years old). For anthropometry, height, weight, and waist- and hip- circumference were measured. They were classified by body mass index(BMI, weight(Kg)/$height^2 $($m^2 $)) and waist-hip ratio(WHR, waist circumference(Cm)/hip circumference(Cm)). The nutrients intake of subjects were compared with the recommended daily allowances(RDA). Mean adequacy ratio(MAR) was calculated. Mean heights, weights, BMIs were higher in the groups with nutrient intake over 125% of RDA than the lower intake groups for most nutrients. However, Mean WHR was the highest in the groups with nutrient intake under 75% of RDA for most nutrients excluding iron intake of women aged 20-64 years. Among women aged 20-64 years, means of MAR were 0.71 for obese individuals(BMI>30), 0.72 for subjects with underweight(BMI<18.5), and 0.76 for subjects with normal weight(18.5$\leq$BMI<25). Normal subjects has statistically significantly higher MAR than those of other groups. However, among elderly people aged over 65 years, obese group had the highest MAR, 0.68. Women with abdominal obesity(WHR>0.9) had lower MAR, 0.71 than those with normal weight(MAR=0.76). From these results, obesity and abdominal obesity seems to be the results of malnutrition including both undernutrition and overnutrition rather than simple problem of excess energy intake. Obesity in elderly people needs to be handled differently from adults.

• 대한의용생체공학회:의공학회지
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• 제41권6호
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• pp.235-246
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• 2020

This study aimed to evaluate the inhibitory effect of micro-current stimulation(MCS) on adipogenesis regarding with Wnt/β-catenin pathway using the ob/ob mouse and 3T3-L1 cell line. 6-week old ob/ob male mice were equally assigned to four groups: obese group(ob), obese with MCS groups(50 μA, 200 μA, and 400 μA). 6-week old C57BL/6J male mice were assigned to the control group(CON). We analyzed abdominal adipose tissue volume by using in vivo micro-CT and measured the body weight, feed intake, liver weight and triglycerides in serum. All the MCS groups showed that significantly reduced body weight and triglycerides in serum. In the case of liver weight and abdominal adipose tissue volume, the inhibitory effect of adipogenesis was shown in the 200 μA and 400 μA groups. To elucidate the anti-obesity effect of MCS, β-catenin, C/EBPα and FAS protein expressions were analyzed by western blotting. β-catenin expression was upregulated, C/EBPα and FAS expression were down-regulated in the relatively high-intensity groups(200 μA and 400 μA). Thus, the 200 μA and 400 μA for the intensity of MCS were chosen for cell experiments. In the 3T3-L1 cell line, Wnt/β-catenin pathway including Wnt10b, Wnt3a, β-catenin and Cyclin D1 was activated in all MCS groups. Accordingly, the expression level of C/EBPα was decreased during the differentiation and lipid droplet was significantly reduced in Oil red O staining results. These results suggest that the Wnt/β-catenin signaling might be activated by MCS with current intensities between 200-400 μA and it may lead to anti-obesity effects.

• 대한의용생체공학회:의공학회지
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• 제38권1호
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• pp.49-55
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• 2017

The prevalence of obesity has noticeably increased worldwide over several decades with various complication. Even though anti-obesity drug treatments have been spotlighted by resulting in effective mean weight losses, its adverse effects cannot be overlooked. Thus, this study aimed to evaluate the effects of multi-frequency whole body vibration, one of the mechanical stimulus, as a countermeasure against obesity. Thirty-two-6-week-old C57BL/6J male mice were equally assigned to four groups: the Control group (CON, n = 8), the Sham group (Sham, n = 8), the sham with single frequency whole body vibration (S+V, n = 8), and the sham with multi frequency whole body vibration (S+MV, n = 8). After 4 weeks, morphologic changes in the adipose tissue were evaluated from three-dimensional images using in vivo micro-computed tomography. At 4 weeks, the volume of the abdominal adipose tissue, which had the highest value in Sham group, noticeably reduced in S+MV group compared to it in S+V group. These results implied that the accumulation of abdominal adipose tissue can be effectively reduced through applying multi-frequency whole body vibration.

• Journal of Nutrition and Health
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• 제38권6호
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• pp.445-454
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• 2005

The purpose of this study was to compare the validity of obese index among body mass index (BMI), waist to hip ratio (WHR), and waist circumference (WC) and to determine which is the best in relation to cardiovascular disease (CVD) risk in Korean elderly more than 65 ages. Data from the 1998 Korean Health and Nutrition Survey were used (n=1017). Anthropometric indices and CVD risk factors were measured, and chi-square test, analysis of variance following duncan's multiple range test, partial correlation analysis, and Receiver Operator Characteristic (ROC) curves were used in the analysis. Anthropometric values were decreased in both male and female when ages were goes up. In female elderly, it specially showed the characteristics of upper body fat and systolic blood pressure risk (p<0.05). Among life style factors the current smokers were prevalent in obese male (p<0.05), but not prevalent in female having obese or upper body fat. Also, person with upper body obesity have more exercise than that of normal group (p<0.01). Mean BMI values of the current smoker was lower than that of normal group in both sexes (p<0.01). Mean BMI value of person with other risk factors were higher than that of normal groups (p<0.05). Among 7 CVD risk factors in partial correlation analysis, WC had the highest correlation coefficient in 5 in male, whereas BMI in 4 in female. In ROC analyses of 12 risk factors and health conditions, the largest area under curve of obese indices for risk factors were WC>WHR>BMI in male and BMI>WHR>WC in female. The optimal cutoff values of each index (BMI : WHR : WC) for one or more risk factors were 19.02 : 0.84 : 71.3 in male and 19.04 : 0.88 : 85.6 in female. In conclusion, Most Korean elderly showed non-obese and abdominal obesity likewise other Asians. Also CVD risk factors were prevalent in Korean elderly within normal limits of obese indices. Therefore the upper body fat indices reflected in the aged whose muscle mass is replaced by fat must be used as an indicator of CVD risk together with BMI. Although WHR was the worst index based on partial correlation analysis and so located between BMI and WC in ROC curve analysis in both sexes, it need to be use with WC to screen the cardiovascular risk group.

• 한국컴퓨터정보학회논문지
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• 제24권4호
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• pp.129-136
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• 2019

The purpose of this study was to provide basic data necessary for the development of clothing that can improve the satisfaction of body shape of elderly men by examining subjective characteristics and characteristics of perception type of older men's body shape. Using the Q methodology, I investigated and analyzed the process of formation and main characteristics of subjectivity of various types of recognition that elderly men express about their body shape. There were four types of perception of body shape in elderly men: flat hip and bird legs skinny body, back bent and abdominal obese body, thick neck and upper body development body, forward cervical neck and protruding abdomen obese body. The actual body shape of elderly men was classified according to the bust, waist circumference, hip circumference, and body part angle. But recognition body shape of elderly men was classified by visual factors like the abdomen, the angle of the neck, the inclination of the back, the slope of the waist, and the degree of obesity. It is necessary to consider the trend of silver fashion which is increasing in demand. In addition, it is necessary to develop clothing patterns of comfortable fit through ergonomic study on the physical characteristics of older men. Consideration should be given to the design and pattern that can reduce the difference between the ideal body shape and the body shape recognized by older men.

• Clinical and Experimental Pediatrics
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• 제48권1호
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• pp.13-20
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• 2005

목 적 : 비만증은 대사성증후군과 더불어 비알코올성 지방간염과 밀접한 관계가 있다. 본 연구는 비만증으로 진단된 학생을 대상으로 비알코올성 지방간염 및 그에 관련된 인자를 알아보고자 하였다. 방 법 : 초 중학교 신체검사상 체질량지수 95 백분위수 이상의 비만아 중 279명을 대상으로 설문지, 신체계측, 혈액검사, 복부지방 초음파 검사를 실시하였다. 결 과 : 전체 연구 대상자 279명 중 비알코올성 지방간염이 있는 사람은 27명으로 9.7%였다. 이중 비만도 30% 이하인 경도비만아 135명 중 5명(3.7%)에서 비알코올성 지방간염이 나타났으며 비만도 30% 이상인 중증도 이상의 비만아에서 비알코올성 지방간염의 유병률은 144명 중 22명(15.2%)으로 비만정도가 심할수록 지방간염의 유병률은 증가하였다. 또한 대사성증후군과 밀접한 연관성이 있다고 알려진 복부 내장지방두께와 허리/엉덩이 둘레비가 클수록 비알코올성 지방간염이 잘 반영되는 것으로 나타났다. 결 론 : 본 연구의 결과는 소아 비만아에서 비알코올성 지방간염의 유병률은 9.7%였으며 비만정도가 심할수록 비알코올성 지방간염의 유병률은 증가하였다. 또한 대사성 증후군의 구성인자와 비알코올성 지방간염은 상당한 연관성이 있으며 이들의 공통적인 특징인 인슐린 저항성의 지표는 치료효과 판정 및 통합적인 위험인자 관리에 도움이 될 것이라 생각된다.

• 디지털융복합연구
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• 제17권3호
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• pp.323-330
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• 2019

본 연구의 목적은 성인의 체질량지수(BMI)와 허리둘레(WC)가 헤모글로빈(Hb)에 미치는 영향을 확인하는 것이다. 국민건강영양조사 제6기 3차년도(2015)자료를 이차분석 하였고 19세 이상의 5621명을 대상으로 하였다. 서술적 통계, t-test, ANOVA 및 Scheffe's test, Pearson correlation coefficient과 다변량 로지스틱 회귀분석을 적용하였다(SPSS WIN 25.0). 결과는, 첫째, BMI에 따라 Hb은 비만에서 가장 높았다(F=97.862, p<0.001). 둘째, WC에 따라 Hb은, 남성 $WC{\geq}90cm$(t=4.909, p<0.001), 여성 $WC{\geq}85cm$(t=5.088, p<0.001)에서 높았다. 셋째, Hb은 BMI(r=0.188, p<0.001) 및 WC(r=0.298, p<0.001)와 양의 상관관계를 나타내었다. 넷째, 남성에서 비만은 고헤모글로빈혈증이 2.30배(p<0.001), $WC{\geq}90cm$은 1.81배(p<0.001)증가하였다. 여성에서 과체중은 1.99배(p=0.002), 비만은 5.66배(p<0.001), $WC{\geq}85cm$은 4.27배(p<0.001) 고헤모글로빈혈증이 증가하였다. 본 연구를 바탕으로 비만예방 및 관리프로그램에 운동, 식이, 교육과 특히 복부비만해소를 위한 운동중재가 포함되어야 한다.

• 대한임상검사과학회지
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• 제51권1호
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• pp.50-56
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• 2019

본 연구는 성인 남성을 대상으로 체질량지수로 분류한 비만 유형에 따른 혈청 GGT와 요산농도의 차이와 관련성을 확인하고자 하였다. 2017년 1월부터 2018년 8월까지 경기지역 종합병원의 건강검진센터를 내원하여 건강검진을 실시한 20세 이상 성인 남성 14,283명을 대상으로 하였다. 비만 기준은 아시아-태평양지역 기준을 적용하였으며, 복부비만은 남성의 허리둘레 90 cm이상을 기준치로 정의하였다. 남성 대상자의 혈청 요산농도 상승은 7.0 mg/dL 이상, 혈청 GGT 상승은 56 IU/L 이상으로 정의하였다. 본 연구결과 혈청 GGT와 요산농도는 정상체중군보다 과체중과 비만군에서 높았으며, 비만군에서는 복부비만을 동반한 경우 혈청 GGT ($53.26{\pm}49.67IU/L$ vs $67.66{\pm}60.16IU/L$) 및 요산농도($6.22{\pm}1.26mg/dL$ vs $6.38{\pm}1.40mg/dL$)가 유의하게 높았다. 그러나 저체중군과는 차이가 없었다. 또한 과체중과 비만군은 정상체중군보다 혈청 GGT 상승과 고요산혈증의 위험이 높게 나타났으나, 저체중은 혈청 GGT 상승과 고요산혈증에 영향을 미치지 않는 것으로 나타났다. 따라서 성인 남성의 과체중 및 비만을 평가하는데 혈청 GGT와 요산이 유용하다고 판단된다.

• 한방재활의학과학회지
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• 제20권4호
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• pp.197-213
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• 2010

Objectives : The clinical trial was designed to investigate the safety and effects of Taeeumjowui-tang(Taiyintiaowei-tang) extracts on the change of the weight, body compositions, serum in obese patients. Methods : This was a 12-weeks, randomized, double blind, placebo-controlled clinical trial. Patients with a body mass index of either greater than $30kg/m^2$ or between 27 and $30kg/m^2$ with controlled hypertension, diabetes, hyperlipidemia were considered eligible. Participants of 41 obese patients were randomized either to Taeeumjowui-tang(Taiyintiaowei-tang)(23) or placebo(18). After 12 weeks of treatment, we measured anthropometric factors(weight, height, waist circumference, BMI(body mass index) etc.), abdominal fat area by CT(computed tomography)scanning, serum lipid(total cholesterol, tryglyceride, HDL-cholesterol, LDL-cholesterol), blood lever of variety(AST, ALT, BUN, creatinine etc.). Adverse events also evaluated. Results : After 12 weeks of treatment mean weight, waist-circumference, total cholesterol, LDL-cholesterol and score of KEAT-26 were significant changed in Taeeumjowui-tang(Taiyintiaowei-tang). There were no serious adverse events in either groups. Conclusions : There were limited in this study that is conducted within a short period of 12 weeks. but its weight and WC(waist circumference), WHR(waist hip ratio), total cholesterol, LDL-cholesterol and score of KEAT-26 loss effect was significant and it had few adverse events.