• Structural Engineering and Mechanics
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• 제80권5호
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• pp.503-522
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• 2021

This paper investigates experimentally and numerically the influence of drilling process on the mechanical and thermomechanical behaviors of woven glass fiber reinforced polymer (GFRP) composite plate. Through the experimental analysis, a CNC machine with cemented carbide drill (point angles 𝜙=118° and 6 mm diameter) was used to drill a woven GFRP laminated squared plate with a length of 36.6 mm and different thicknesses. A produced temperature during drilling "heat affected zone (HAZ)" was measured by two different procedures using thermal IR camera and thermocouples. A thrust force and cutting torque were measured by a Kistler 9272 dynamometer. The delamination factors were evaluated by the image processing technique. Finite element model (FEM) has been developed by using LS-Dyna to simulate the drilling processing and validate the thrust force and torque with those obtained by experimental technique. It is found that, the present finite element model has the capability to predict the force and torque efficiently at various drilling conditions. Numerical parametric analysis is presented to illustrate the influences of the speeding up, coefficient of friction, element type, and mass scaling effects on the calculated thrust force, torque and calculation's cost. It is found that, the cutting time can be adjusted by drilling parameters (feed, speed, and specimen thickness) to control the induced temperature and thus, the force, torque and delamination factor in drilling GFRP composites. The delamination of woven GFRP is accompanied with edge chipping, spalling, and uncut fibers.

• 한국대기환경학회지
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• 제17권2호
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• pp.193-201
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• 2001

Acidic air pollutants were collected to characterize indoor air quality in a residential area in the summer. All indoor and outdoor samples were measured simultaneously using an annular denuder system(ADS) in Seoul. The data set was collected from July 26 to September 11, 1997. The mean indoor/outdoor ratios measured from this study were : 0.34 for $HNO_3$; 0.91 for $HNO_2$; 0.22 for $SO_2$; 1.34 for $NH_3$; 0.78 for $PM_{2.5}(d_p$ <2.5 $mutextrm{m}$); 0.90 for $SO_{4}^{2-}$; 0.68 for $NO_{3}^{-}$ and 0.79 for $NH_{4}^{+}$. Indoor concentrations of $HNO_3$, $SO_2$ and $PM_{2.5}$ were highly correlated with the outdoor concentrations. The relationship between indoor and outdoor air is dependent, to a large extent, on the rate of air exchange between these two environments. A tracer-gas decay technique with sulfur hexafluoride ($SF_{6}$) as a tracer gas was used to estimate the air exchange of a private home in the summer. The average air exchange rate was estimated to be 23.7 hr(sup)-1. The deposition velocities for $SO_{4}^{2-}$, $NO_{3}^{-}$ and $NH_{4}^{+}$ calculated were 0.17, 0.69 abd 0.39 cm/sec, respectively.

• The Korean Journal of Pain
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• 제31권3호
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• pp.206-214
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• 2018

Background: Immune responses appear to be affected by anesthetics and analgesics. We investigated the effects of caudal tramadol on the postoperative immune response and pain management in pediatric patients. Methods: Sixty ASA-I pediatric patients aged 3-10 years undergoing lower abdominal surgery. Patients were randomly assigned either to a caudal bupivacaine (0.25%) group (group B), or a group that received caudal tramadol (1 mg/kg) added to the bupivacaine (0.25%) (group T). Both were diluted in a 0.9% NaCl solution to a total volume of 1ml/ kg. The systemic immune response was measured by collecting blood samples preoperatively, at the end of anesthesia, and at 24 and 72 hours postoperatively, and studied for interleukin IL-6, C-reactive proteins (CRP) cortisol levels, and leucocytes with its differential count. Postoperative pain was assessed along with sedation scales. Results: Postoperative production of IL-6 was significantly higher in group B at the end of anesthesia, than at the $24^{th}$ hour, and at the $72^{nd}$ hour in group B and group T, respectively. The immune response showed leukocytosis with increased percentages of neutrophil and monocytes, and a decreased lymphocyte response rate within both groups with no significant differences between the groups. Cortisol and CRP were significantly higher in group B. Conclusions: Adding tramadol to a caudal bupivacaine block can attenuate the pro-inflammatory cytokine response, Cortisol, and CRP in children undergoing lower abdominal surgery.

• 인지과학
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• 제7권3호
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• pp.37-60
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• 1996

생물심리학적 관점에서,학습은 우리가 환경으로부터 얻은 정보를 뇌내 신경세표의 회로망으로 전이시키는 과정이라 할 수 있다. 학습과 기억의 생물할적 실체를 찾고자 하는 연구들에는,기억 또는 정보의 저장이 신경계내 시냅스수정의 방식으로 이루어진다는 가정하에,특정 유형의 학습과 관련된 신경회로를 규명하고 신경가소성의 기초를 밝히려는 노력들이 있었다.이와는 달리 신경계내 뉴련들로 연결된 복잡한 신경망의 형태들이 특정정보를 표상한다고 보고,학습과 기억에 관련된 신경구조물들의 상호작용 기초를 분석 하려는 노력들이 있었다.본 연구는,전자의 입장에서,학습과 기억에 필수적인 엔그램의 부위를 찾기 위하여 사용된느 연구방법과 주요 실험동물 모델체계들의 특성,그리고 이러한 모델체계들을 사용한 연구결과들을 개관하였다.즉,본 논고는 실험동물 모델체계를 사용하여 학습과 기억에 필수적으로 관여하는 기억흔적회로를 찾아내고,그 신경회로내에서 학습과 기억에 결정적인 신경의 가소적 변화가 일어나는 부위를 규명하며,학습과정중에 신경수준에서 일어나는 시냅스의 수정에 대한 신경생리적,생화학적 기제를 밝히고자 한 연구들을 개관하였다.

• Toxicological Research
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• 제24권3호
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• pp.207-212
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• 2008

Pesticide residues play several key roles as environmental and food pollutants and it is crucial to develop a method for the rapid determination of pesticide residues in environments. In this study, a simple, effective, and sensitive method has been developed for the quantitative analysis of methoxyfenozide in water and soil when kept under laboratory conditions. The content of methoxyfenozide in water and soil was analyzed by first purifying the compound through liquid-liquid extraction and partitioning followed by florisil gel filtration. Upon the completion of the purification step the residual levels were monitored through high performance liquid chromatography(HPLC) using a UV absorbance detector. The average recoveries of methoxyfenozide from three replicates spiked at two different concentrations and were ranged from 83.5% to 110.3% and from 98.1% to 102.8% in water and soil, respectively. The limits of detection(LODs) and limits of quantitation(LOQs) were 0.004 vs. 0.012 ppm and 0.008 vs. 0.024 ppm, respectively. The method was successfully applied to evaluate the behavioral fate of a 21% wettable powder(WP) methoxyfenozide throughout the course of 14 days. A first-order model was found to accurately fit the dissipation of methoxyfenozide in water with and a $DT_{50}$ value of 3.03 days was calculated from the fit. This result indicates that methoxyfenozide dissipates rapidly and does not accumulate in water.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제15권7호
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• pp.2455-2475
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• 2021

Patient Navigation Program (PNP) is considered as an important implementation of health care systems that can assist in patient's treatment. Due to the feasibility of PNP implementation, a systematic reuse is needed for a wide adoption of PNP computerized system. SPL is one of the promising systematic reuse approaches for creating a reusable architecture to enabled reuse in several similar applications of PNP systems which has its own variations with other applications. However, stakeholder decision making which result from the imprecise, uncertain, and subjective nature of architecture selection based on quality attributes (QA) further hinders the development of the product line architecture. Therefore, this study aims to propose a quality-driven approach using Multi-Criteria Decision Analysis (MCDA) techniques for Software Product Line Architecture (SPLA) to have an objective selection based on the QA of stakeholders in the domain of PNP. There are two steps proposed to this approach. First, a clear representation of quality is proposed by extending feature model (FM) with QA feature to determine the QA in the early phase of architecture selection. Second, MCDA techniques were applied for architecture selection based on objective preference for certain QA in the domain of PNP. The result of the proposed approach is the implementation of the PNP system with SPLA that had been selected using MCDA techniques. Evaluation for the approach is done by checking the approach's applicability in a case study and stakeholder validation. Evaluation on ease of use and usefulness of the approach with selected stakeholders have shown positive responses. The evaluation results proved that the proposed approach assisted in the implementation of PNP systems.

• 의료법학
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• 제14권2호
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• pp.217-260
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• 2013

In connection to the civil liability of the medical malpractice, plaintiff and courts are solving the medical disputes with theory of the liability based on tort law. because contract law does not enact the right of claim of solatium and a plaintiff's lawyer and courts hesitate to use contract law. Medical treatment of doctor is main debt in medical contract and its in-complete performance gives rise to the violations of human's life, body and health. Consequently a breach of medical contract leads to violations of person-al rights. These violations spring from liability of contract as well as tort and damages from them are recognized based on medical contract law. A duty of explanation of doctor is a independent and appendant debt to the treatment debt. However its breach provokes violations of human's life, body and health as well as a right self-determination. Therefore consolation money claim should be recognized. In case of the violation of patient's life, body and health, patient's family al-so can demand consolation money due to the violation of their's own mental pain. However in case of the violation of only patient's self-determination without informed concent, they can not demand it by reason of the violation of patient's self-determination. But by reason of the violation of patient's life, body and health that were recognized by proximate causal relation between violation of duty of explanation and abd execution, they can do.

• 사회복지연구
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• 제44권1호
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• pp.5-31
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• 2013

본 연구는 대도시 남성노숙인 시설에서 알코올 의존 노숙인들을 위한 치료공동체 프로그램을 수료하고 현재 회복 중인 6인의 회복 체험에 대한 현상학적 연구이다. 드러난 회복의 의미는 다음과 같다. 첫째 공간적 회복이다. 이들은 자신들이 누워있던 거리를 떠나 공동체에 터를 잡으면서 자신을 바라보는 새로운 시선에 둘러싸이게 된다. 둘째, 신체적 회복으로 눕던 자세에서 벗어나 몸을 일으키면서 이들은 자신의 몸과 마음의 움직임의 주체가 된다. 셋째, 연구참여자들의 시간적 회복은 과거와 현재를 수용하고 미래를 품는 현상으로 드러난다. 넷째, 관계의 회복으로 연구참여자들은 관계망을 통해 사회 내에서 자신의 자리를 만들어 간다. 이들의 사회내에서의 자리는 지위라기보다는 관계망 속에 존재한다. 이러한 연구결과를 토대로 알코올 의존 노숙인에 대한 개입을 위한 실천 함의를 도출하였다.

• Journal of Preventive Medicine and Public Health
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• 제52권4호
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• pp.205-213
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• 2019

Objectives: Maternal folic acid supplementation is considered mandatory in almost every country in the world to prevent congenital malformations. However, little is known about the association of maternal folic acid intake with the occurrence of childhood cancer. Hence, this study aimed to determine the effects of maternal folic acid consumption on the risk of childhood cancer. Methods: A total of 158 related articles were obtained from PubMed, Google Scholar, Scopus, and ProQuest using standardized keywords, of which 17 were included in the final review. Results: Eleven of the 17 articles showed a significant protective association between maternal folic acid supplementation and childhood cancer. Using a random-effects model, pooled odds ratios (ORs) showed a protective association between maternal folic acid supplementation and childhood acute lymphoblastic leukaemia (OR, 0.75; 95% confidence interval [CI], 0.66 to 0.86). However, there was no significant association between maternal folic acid supplementation and acute myeloid leukaemia (OR, 0.70; 95% CI, 0.46 to 1.06) or childhood brain tumours (OR, 1.02; 95% CI, 0.88 to 1.19). Conclusions: Maternal folic acid supplementation was found to have a protective effect against childhood acute lymphoblastic leukaemia. Thus, healthcare professionals are recommended to provide regular health education and health promotion to the community on the benefits of folic acid supplementation during pregnancy.

• 대한치과교정학회지
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• 제52권6호
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• pp.399-411
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• 2022

Objective: The objective of this randomized clinical trial was to study the skeletal and dental effects of low-level laser therapy (LLLT) along with a miniscrew-assisted expander (Hyrax) after six months of retention. Methods: After sequence generation, concealed allocation, and implementation, 24 female patients were randomly divided (1:1) into two-groups: bone-borne rapid palatal expansion (BBE) without LLLT (n = 12) and BBE with LLLT (n = 12). Eligibility criteria included female patients aged 10-13 years old with bilateral posterior crossbites. Intraoral and extraoral photographs, cone-beam computed tomography images, and digital study models were obtained before expansion and six months after retention. The 7 mm Hyrax appliance was anchored to four palatal mini-screws, which were activated twice daily for 15 days, then locked and kept in place as a retainer. LLLT was performed in the laser group during expansion and retention, according to the guidelines provided. Results: The records of 24 patients were analyzed. According to the post-retention measurements, both groups showed a significant increase in nasal and maxillary widths and total facial height. In the laser group, the Sella-Nasion-Point A and Point A-Nasion-Point B angles and the interpremolar apical distance were significantly increased. Conclusions: Within the limitations of this study, the results suggest that the parameters and protocol of LLLT do not clinically affect the efficiency of BBE in prepubertal and pubertal patients.