• Title/Summary/Keyword: aPTT

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Prediction pulse transit time using electrocardiogram (심전도를 사용한 맥파전달시간차 예측)

  • Jeong, ChangGil;Yoo, JaeChern
    • Proceedings of the Korea Information Processing Society Conference
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    • 2021.05a
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    • pp.514-516
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    • 2021
  • 본 연구는 심혈관계 질환 진단에 주고 사용되는 PTT 를 계산할 때 필요한 PPG 신호가 없을 경우 ECG 신호만을 사용하여 PTT 값을 예측하는 방법을 제안한다. MIMIC-I 데이터셋에서 2 채널 심전도 데이터와 광전용적맥파 데이터를 확보하여 제안하는 방법을 적용하였을 때, RMSE 0.07116 으로 예측하였다. 본 연구는 향후 단일 생체신호만 측정할 수 있는 제한된 상황에서 대안으로 활용될 수 있을 것이다.

A Study of Cycling Exercise which uses a Target Heart Beat for Cardiorespiratory Function Improvement (목표심박수를 이용한 자전거 운동의 심폐능력 향상 연구)

  • Kim, Sung-Min;Kang, Seung-Ho;Lee, Man-Pyo;Jung, Whoi-Seong;Jang, Won-Seuk
    • Journal of the Institute of Electronics Engineers of Korea SC
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    • v.45 no.5
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    • pp.35-43
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    • 2008
  • In this study we confirmed for the cardiopulmonary ability improvement of the cycling exercise which uses a target heart beat. Consequently, we looked the resting systolic blood pressure down at 2.98% and THBI(Total Heart Beat Index) also decrements at 7.59%. But, increase of $VO_2$ max and PTT(Pulse Transit Time)were each point 24.60% and 4.92%. Increase of $VO_2$ max showed the growth of stroke volume by myocardial development. The increase of a stroke volume induces the decrease of Heart rate. The blood pressure was reduced also though the blood of many quantity was supplied at the artery. The reason is the phenomenon to be due to by an elasticity increase of the artery. We found out it through the decrease of PTT. So the cycling exercise to use consequently the target heart beat will become big aid at the health care.

Anticoagulant activities of oleanolic acid via inhibition of tissue factor expressions

  • Lee, Won-Hwa;Yang, Eun-Ju;Ku, Sae-Kwang;Song, Kyung-Sik;Bae, Jong-Sup
    • BMB Reports
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    • v.45 no.7
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    • pp.390-395
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    • 2012
  • Oleanolic acid (OA), a triterpenoid known for its anti-inflammatory and anti-cancer properties, is commonly present in several medicinal plants but its anticoagulant activities have not been studied. Here, the anticoagulant properties of OA were determined by monitoring activated partial thromboplastin time (aPTT), prothrombin time (PT), fibrin polymerization as well as cell-based thrombin and activated factor X (FXa) generation activities. Data showed OA prolonged aPTT and PT significantly and inhibited thrombin catalyzed fibrin polymerization. In addition, OA inhibited the activities of thrombin and FXa and inhibited the generation of thrombin or FXa in human endothelial cells. OA also inhibited TNF-${\alpha}$-induced tissue factor expression on human endothelial cells. In accordance with these anticoagulant activities, OA showed an anticoagulant effect in vivo. These results indicate that OA possesses antithrombotic activities and suggest that daily consumption of a herb containing OA may be preventing thrombosis in pathological states.

Study on Application of Reinforcement Device to Provide Greater Dynamic Stability for Power Transmission Towers and its Effect

  • Yang, Kyeong-hyeon;Bae, Choon-hee;Jeong, Nam-geun;Kim, Doo-young;Kim, Sung-min;Jang, Yong-hee
    • KEPCO Journal on Electric Power and Energy
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    • v.2 no.1
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    • pp.33-41
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    • 2016
  • To verify that the friction damper used to high buildings as a kind of control technology of wind vibration can reduce dynamic behaviors of PTTs effectively, slip dampers in this paper are proposed to absorb the energy through relatively frictional movement of slip dampers applied to main post of a PTT (Power Transmission Tower) when dynamic displacement of a PTT occurs. The result of dynamic analysis is presented to determine the capacity of the damper system by controlling damping ratio on the resonance condition. It is observed that by installing slip dampers at a PTT the strain amplitudes of the main post caused by wind load are effectively reduced. Therefore it is shown that the proposed damper satisfies the strengthened wind-load design standards, and its efficacy was also validated experimentally by field testing.

Polyester Nanocomposite Fibers with Organoclay; Thermo-Mechanical Properties and Morphology of PBT, PET, and PTT (유기화 점토를 이용한 폴리에스테르 나노복합체 섬유; PBT, PET, 그리고 PTT의 열적-기계적 성질 및 모폴로지)

  • Kim Sung Jong;Mun Mu Kyung;Chang Jin-Hae
    • Polymer(Korea)
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    • v.29 no.2
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    • pp.190-197
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    • 2005
  • Nanocomposites of three different polyesters with dodecyltriphenylphosphonium-montmorillonite $(C_{12}PPh-MMT)$ as an organoclay are compared with their thermal properties, mechanical properties, and morphologies. Poly (butylene terephthalate) (PBT), poly(ethylene terephthalate) (PET), and poly(trimethylene terephthalate) (PTT) were used as matrix polymers in the fabrication of polyester nanocomposite fibers. The variations of their properties with organoclay content in the polymer matrix and draw ratio (DR) are discussed. Transmission electron microscopy (TEM) micrographs show that some of the clay layers are dispersed homogeneously within the polymer matrix on the nano-scale, although some clay particles are agglomerated. We also found that the addition of only a small amount of organoclay is enough to improve the thermal stabilities and mechanical properties of the polyester nanocomposite fibers. Even polymers with low organoclay contents $(<5\;wt\%)$ were found to exhibit much higher strength and modulus values than pure polyester fibers. In the cases of all polyester hybrid fibers, the values of the tensile mechanical properties were found to decrease linearly with increasing DR. However, the initial tensile modulus of the PTT hybrid fibers were found to be independent of DR.

Comparative Studies of Perceiving Korean Monosyllabic Digit Words under Different Speech Compression Schemes (음성압축 방식의 변화가 한국어 단음절 숫자 인지기능에 미치는 영향의 비교 연구)

  • Lim, Dukhwan;Won, Yookyung
    • The Journal of the Acoustical Society of Korea
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    • v.32 no.3
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    • pp.262-268
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    • 2013
  • The performances of speech compression schemes appeared to be dependent on the response profiles to compressed stimuli and the features of individual languages to some extent. Although these response profiles were critical in comparing various compression outcomes, the related data were limited in number for Korean monosyllabic words. From the previous study, data from PNT (Preserving No Trait) compression was selected as a base set for comparison. In this study, the outcomes from PPT (Preserving Pitch Trait) and PTT (Preserving Time Trait) were analyzed under the same condition. Then, the properties of these three widely used representative compression schemes were quantitatively compared in normal hearing adults (N=20) for controlled Korean quintet digit sets (0 through 9). Results showed that PPT compression scheme exhibited the best perceptual performances for the Korean quintet digit sets in the final outcomes (PPT>PTT>PNT). The compression ratios of 50% performances were estimated as about 20%, 42%, and 44% for PPT, PTT, and PNT, respectively. The data indicated the influences of the salient psychoacoustic features of the three representative compressions on perceiving Korean monosyllabic digit words. This controlled procedure with monosyllabic quintet sets can evaluate efficiency and effectiveness of other compression schemes and may also contribute to diagnosing auditory processing disorders and fitting special hearing aids with compression issues.

The Effect of Fat Diet on Inflammatory Markers and Blood Coagulation System in Rats

  • Choi, Seok-Cheol;Seok, Seong-Ja
    • Biomedical Science Letters
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    • v.18 no.3
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    • pp.237-243
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    • 2012
  • This study was undertaken to know the effect of fat diet (for eight weeks) on changes of inflammatory markers [tumor necrosis factor (TNF-${\alpha}$) and prostaglandin $E_2$ ($PGE_2$)] and blood coagulation system [platelet aggregation function (PAF), prothrombin time (PT), activated partial thromboplastin time (aPTT)] in rats. Serum TNF-${\alpha}$, $PGE_2$, biochemical markers, PAF, PT, aPTT, and body weight were measured and compared between the control (normal diet-rats) and the fat group (fat diet-rats). The weights in the fat group were higher than those of the control group. TNF-${\alpha}$, $PGE_2$, glucose, aspartate aminotransferase (AST), alanine aminotransferase (ALT), and creatinine levels were greater in the fat group compared with the control group. The degree of platelet aggregation was lower, whereas PT and aPTT levels were longer in the fat group than in the control group. These findings have shown that fat diet may cause inflammatory response, diabetes, liver and renal dysfunction, and disturbances of fibrinolysis and coagulation system.

Design and Implementation of Real-time Blood Pressure Measuring System using Smartphone (스마트폰을 이용한 실시간 혈압측정 시스템의 설계 및 구현)

  • Gil, Yeongjoon;Lee, Jungtae
    • KIISE Transactions on Computing Practices
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    • v.21 no.3
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    • pp.192-214
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    • 2015
  • Blood pressure may be measured using physiological signals, such as ECG, PTT, and $SpO_2$. In this study, we designed and implemented a portable real-time blood pressure measuring system, which can access the Internet simultaneously using the IPv4 / IPv6 protocol. In addition, we presented a model for the calculation of systolic and diastolic blood pressure in a real-time environment. Through clinical experiments on 28 subjects, the blood pressure measuring system was shown to satisfy the requirements of Grade B level of the BHS (British Hypertension Society) certification.

A Study on the Channel Converting and Monitoring of the Remote Control Transceiver (원격제어 송수신기의 채널변환과 모니터용 모듈의 구현)

  • 조학현;최조천;김기문
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.3 no.2
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    • pp.347-354
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    • 1999
  • Generally, transceiver is operated to the remote control for the purpose of breading the traffic zone which is established on a mountain peak, island and building top using private line. Therefor, the remote control system of public radio station have been the very important role that is decision the quality relate to the quickness, accuracy, safety of communication on old type transceiver of SSB, VHF etc. In the case of using the only 1 private line which is exchanged voice signal with data signal had mixed or interrupted for up/down of channel, PTT control and monitoring of transmission channel and power. The up/down of channel and PTT control is according to the ASK and the data of monitoring is transfered to the FSK modulation, additional algorithm is studied on the serial protocol and traffic sequence using the MCS-51 processor in the simplex communication methode.

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Effect of a Combinacon of Mental Activity with Experimental Subway Noise on Hematology (실험적 지하철 소음에서의 지적활동이 혈액생리에 미치는 영향)

  • Choi, Seok-Cheol;Hyun, Kyung-Yae;Park, Jae-Hyun;Kwon, Heun-Young
    • Journal of Life Science
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    • v.16 no.7 s.80
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    • pp.1174-1180
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    • 2006
  • The present study was sought to clarify whether the combination of mental activity with subway noise affects hematological variables. Fifty-six healthy volunteers participated in this experiment and underwent a stress task consisting of combination_of mental activity (mental arithmetic) with subway noise for 50 min and 60min of recovery after the end of the stress task. Venous blood samples were collected for measuring CBC, prothrombin time (PT), activated partial thromboplastin time (aPTT), erythrocyte sedimentation rate (ESR), fibrinogen concentration, D-dimer and high sensitive C-reactive protein (H-CRP) levels before (baseline), 50min of stress task (S-50m), and 60 min of recovery (R-60m). Total leukocyte, neutrophil and lymphocyte counts significantly increased at R-60m compared with baselines. RBC count at S-50m was higher, while monocyte counts at S-50m and R-60m were lower than those of baselines. aPTTs shortened at S-50m and R-60m, but PT reduced at R-60m as compared with baselines. D-dimer and H-CRP levels at S-50m and R-60m were significantly higher than those of baselines. These findings imply that a combination of mental activity with subway noise nay cause leukocytosis, homo-concentration, shortened PT and aPTT, decreased ESR, and raised D-dimer and H-CRP levels, suggesting possible development of inflammation and prothrombogenic reaction attributable to a subway environment.