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Effects of Head-Down Tilt$(-6^{\circ})$ on Hemodynamics and Plasma Catecholamine Levels (도립$(-6^{\circ})$이 혈장 Catecholamine 및 심장혈관계에 미치는 영향)

  • Song, Dae-Kyu;Bae, Jae-Hoon;Park, Won-Kyun;Chae, E-Up
    • The Korean Journal of Physiology
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    • v.21 no.2
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    • pp.211-223
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    • 1987
  • Head-down tilt (HDT) at $-6^{\circ}$ has been commonly used as the experimental model in both man and animals to induce the blood shift toward the head or central protion of the body, demonstrating similar physiological effect encountered in the weightlessness in the orbital flight. There are few reports about the physiological response upon the cardiovascular regulatory system or the tolerance to the $(-6^{\circ})$ HDT within a relatively short period less than 1 hour. Therefore, the purpose of this study way to observe the effects of $-6^{\circ}$ HDT on cardiovascular system within 30 minutes and to evaluate early regulatory mechanism for simulated hypogravity. Ten mongrel dogs weighing 8-12 kg were anesthetized with the infusion of 1% ${\alpha}-chloralose$ (100 mg/kg) intravenously, and the postural changes were performed from the supine to the $-6^{\circ}$ head-down Position, then from the head-down to the supine (SUP), and each posture was maintained for 30 minutes. Blood flow $({\dot{Q}})$ through common carotid and femoral arteries were determined by the electromagnetic flowmeter. Mean arterial pressure (MAP), heart rate (HR), respiratory rate , and pH, $P_{O_2}$, $P_{CO_2}$ and hematocrit (Hct) of arterial and venous blood were also measured. The peripheral vascular resistance was calculated by dividing respective MAP values by ${\dot{Q}}$ through both sides of common carotid or femoral arteries. The concentration of plasma epinephrine and norepinephrine was determined by Peuler & Johnson's radioenzymatic method. The results are summarized as follows: In the initial 5 minutes in $-6^{\circ}$ HDT, HR was significantly (p<0.05) increased and MAP slightly decreased. Although ${\dot{Q}}$ and carotid peripheral artery resistance were not significantly changed, ${\dot{Q}}$ through femoral artery was diminished and femoral peripheral artery resistance was elevated. In the SUP, the initial changes of MAP and HR were increased (p<0.05), but those of ${\dot{Q}}$ and peripheral vascular resistance through both common carotid and femoral arteries were not significant. After 10 minutes of each postural change in both HDT and SUP, MAP was maintained almost equal to that of the level of pretilting control. During 60 minutes of both postural changes of HDT and SUP, $P_{O_2}$ and Hct were not changed significantly. However pH tended to increase slowly and $P_{CO_2}$ was gradually decreased. The pH and $P_{CO_2}$ seemed to be related to the increased respiratory rate. Plasma epinephrine concentration was not changed significantly and plasma norepinephrine concentration was slightly decreased in the course of HDT and also at 10 minutes of SUP. However these concentration changes were statistically insignificant. From these results, it may be concluded that the effect of $-6^{\circ}$ HDT for 30 minutes on the cardiovascular system and plasma catecholamine levels of the dog is minimum and it is suggestive that the cardiovascular regulatory mechanism, possibly mediated by so called gravity receptors including baroreceptor and volume receptor, has been properly and adequately operated.

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EVALUATION OF RADIOPACITY AND DISCRIMINABILITY OF VARIOUS FIBER REINFORCED COMPOSITE POSTS (수종의 섬유 강화 레진 포스트의 방사선 불투과도와 식별도 평가)

  • Lee, Eun-Hye;Choi, Hang-Moon;Park, Se-Hee;Kim, Jin-Woo;Cho, Kyung-Mo
    • Restorative Dentistry and Endodontics
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    • v.35 no.3
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    • pp.188-197
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    • 2010
  • The purpose of this study was to compare radiopacity and radiographic discriminability of various FRC-Posts. Six FRC-Posts were investigated ; 1) FRC Postec Plus (Ivoclar Vivadent AG, Schaan, Liechtenstein), 2) Snowlight (Carbotech, Lewis center, OH, USA), 3) Dentin Post (Komet Brasseler, Lamgo, Germany), 4) Rely-X Fiber Post (3M ESPE, St.paul, MN, USA), 5) D.T.-Light Post (BISCO, Schaumburg, IL,USA), 6) Luxapost (DMG, Hamburg, Germany) The radiographs of each post with a reference 1 mm / 2 mm aluminum step-wedge was taken using digital sensor. The optical density were calculated by gray value of $10{\times}10$ pixel and compared in mm Al equivalent at five points. Six maxillary incisors of similar radiopacity were used. Radiographs of posts in Mx. incisors of lingual side of dry mandible were taken. We showed radiographs and asked the questionnaire to 3 radiologists, 3 endodontists, 3 general practitioners. The questionnaire was comprised of choices of the highest, lowest radiopaque individual post and the choices of best discriminable post at apical, coronal area. The following results were obtained. 1. Each post system showed various radiopacity. 2. There was change of discriminability between each post and simulated specimens regardless of examiner. Although each post showed various radiopacity, the difference of radiopacity did not affect on discriminability.

Intracellular Concentrations of NAD(P), NAD(P)H, and ATP in a Simulated Oxic-settling-anaerobic (OSA) Process (OSA 공정의 세포 내 ATP, NAD(H), NADP(H) 농도)

  • Ventura, Jey-R Sabado;Nam, Ji-Hyun;Yang, Benqin;Na, Ri;Kil, Hyejin;Nam, Deok-Hyeon;Kang, Ki-Hoon;Jahng, Deokjin
    • Journal of Korean Society on Water Environment
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    • v.31 no.6
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    • pp.599-609
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    • 2015
  • In order to investigate why OSA (oxic-settling-anaerobic) process produces less sludge than CAS (conventional activated sludge) process, sequential cultivation through 1st aerobic-anaerobic-2nd aerobic conditions, were carried out. Then, the intracellular concentrations of adenosine triphosphate (ATP), nicotinamide adenine dinucleotide (NAD and NADH), and nicotinamide adenine dinucleotide phosphate (NADP and NADPH) were monitored for these three stages. Results showed that the concentrations of these energy substances rapidly decreased through time in both aerobic and anaerobic conditions but the anaerobic culture contained the lower energy level than aerobic culture. The 2nd aerobic culture that experienced anaerobic condition showed lower concentration of these energy substances than those of the 1st aerobic culture. Meanwhile, the anaerobic culture corresponding to the sludge holding stage of OSA was subjected to different soluble chemical oxygen demand (SCOD) levels, detention time, and temperature to evaluate the effects of these variations on the energy level difference between the 1st and 2nd aerobic stages. The lower the SCOD concentration, the longer detention time; and the higher temperature in the anaerobic stage tended to further reduce the intracellular level of the 2nd aerobic culture. On the average, the intracellular energy level of the anaerobic and 2nd aerobic stage were 57.73% and 39.12% of the 1st aerobic culture, respectively. These indicated that the insertion of an anaerobic stage between two aerobic stages could lower the intracellular energy levels, hence the lower the sludge in OSA than CAS process. Moreover, manipulation of the operating conditions of the intervening anaerobic stage can change intracellular energy levels thereby controlling sludge production.

Evaluation of Future Water Deficit for Anseong River Basin Under Climate Change (기후변화를 고려한 안성천 유역의 미래 물 부족량 평가)

  • Lee, Dae Wung;Jung, Jaewon;Hong, Seung Jin;Han, Daegun;Joo, Hong Jun;Kim, Hung Soo
    • Journal of Wetlands Research
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    • v.19 no.3
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    • pp.345-352
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    • 2017
  • The average global temperature on Earth has increased by about $0.85^{\circ}C$ since 1880 due to the global warming. The temperature increase affects hydrologic phenomenon and so the world has been suffered from natural disasters such as floods and droughts. Therefore, especially, in the aspect of water deficit, we may require the accurate prediction of water demand considering the uncertainty of climate in order to establish water resources planning and to ensure safe water supply for the future. To do this, the study evaluated future water balance and water deficit under the climate change for Anseong river basin in Korea. The future rainfall was simulated using RCP 8.5 climate change scenario and the runoff was estimated through the SLURP model which is a semi-distributed rainfall-runoff model for the basin. Scenario and network for the water balance analysis in sub-basins of Anseong river basin were established through K-WEAP model. And the water demand for the future was estimated by the linear regression equation using amounts of water uses(domestic water use, industrial water use, and agricultural water use) calculated by historical data (1965 to 2011). As the result of water balance analysis, we confirmed that the domestic and industrial water uses will be increased in the future because of population growth, rapid urbanization, and climate change due to global warming. However, the agricultural water use will be gradually decreased. Totally, we had shown that the water deficit problem will be critical in the future in Anseong river basin. Therefore, as the case study, we suggested two alternatives of pumping station construction and restriction of water use for solving the water deficit problem in the basin.

Analysis of Flood Control Effect by Applying the Connecting Channel in Estuary Area Including the Confluence of Two Rivers (2개의 하천이 합류하는 하구역에서의 연결수로 통수능에 따른 홍수위저감효과 분석)

  • Kim, Sooyoung;Kim, Hyung-Jun;Yoon, Kwang Seok
    • Journal of Korea Water Resources Association
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    • v.48 no.12
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    • pp.1065-1075
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    • 2015
  • In the estuary where the structure such as river-mouth weir has been installed, the flow is developed very complicatedly due to river water from upstream, tide of the sea and floodgate operation. Especially, if basin outlets more than one exists in one estuary, the boundary conditions will be significantly more complex form. Saemangeum(SMG) project area in Korea is the most typical example. There are Mankyung river and Dongjin river in upstream. The water of them inflows into SMG project area. In the downstream, river flow was drained from inland to sea over the SMG sea dike through the sluice. The connecting channel was located between Mankyung and Dongjin basins. It functions not only as transportation by ship in ordinary period but also as flood sharing by sending flood flow to each other in flood period. Therefore, in order to secure the safety against flood, it is very important to understand the flood sharing capacity for connecting channel. In this study, the flood control effect was analyzed using numerical simulation. Delft3D was used to numerical simulation and simulated period was set up with neap tide, in which the maximum flood stage occurred due to poor drainage. Actually, three connecting channels were designed in land use plan of the SMG Master Plan, but they were simplified to a single channel for conciseness of analysis in this study. According to the results of numerical analysis, the water level difference between two basins was increased and the maximum flood stage at dike sluice was also upraised depending on decrease of conveyance. And the velocity induced by same water level difference was decreased when the conveyance became smaller. In certain conveyance above, there was almost no flood control effect. Therefore, if the results of this study are considered for design of connecting channel, it will be expected to draw the optimal conveyance for minimizing dredging construction cost while maximizing the flood control effect.

Three-Dimensional Finite Element Analysis of Internal Connection Implant System (Gsii$^{(R)}$) According to Three Different Abutments and Prosthetic Design (국산 내부연결형 임플란트시스템(GS II$^{(R)}$)에서 지대주 연결방식에 따른 응력분석에 관한 연구)

  • Jang, Mi-Ra;Kwak, Ju-Hee;Kim, Myung-Rae;Park, Eun-Jin;Park, Ji-Marn;Kim, Sun-Jong
    • Journal of Dental Rehabilitation and Applied Science
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    • v.26 no.2
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    • pp.179-195
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    • 2010
  • In the internal connection system, the loading transfer mechanism within the inner surface of the implant and also the stress distribution occuring to the mandible can be changed according to the abutment form. Therefore it is thought to be imperative to study the difference of the stress distribution occuring at the mandible according to the abutment form. The purpose of this study was to assess the loading distributing characteristics of three different abutments for GS II$^{(R)}$ implant fixture(Osstem, Korea) under vertical and inclined loading using finite element analysis. Three finite element models were designed according to three abutments; 2-piece Transfer$^{TM}$ abutment made of pure titanium(GST), 2-piece GoldCast$^{TM}$ abutment made of gold alloy(GSG), 3-piece Convertible$^{TM}$ abutment with external connection(GSC). This study simulated loads of 100N in a vertical direction on the central pit(load 1), on the buccal cusp tip(load 2) and $30^{\circ}$ inward inclined direction on the central pit(load 3), and on the buccal cusp tip(load 4). The following results were obtained. 1. Without regard to the loading condition, greater stress was concentrated at the cortical bone contacting the upper part of the implant fixture and lower stress was taken at the cancellous bone. 2. When off-axis loading was applied, high stress concentration observed in cervical area. 3. GSG showed even stress distribution in crown, abutment and fixture. GST showed high stress concentration in fixture and abutment screw. GSC showed high stress concentration in fixture and abutment. 4. Maximum von Mises stress in the surrounding bone had no difference among three abutment type. In GS II$^{(R)}$ conical implant system, different stress distribution pattern was showed according to the abutment type and the stress-induced pattern at the supporting bone according to the abutment type had no difference among them.

Study on Hydrogen Production and CO Oxidation Reaction using Plasma Reforming System with PEMFC (고분자 전해질 연료전지용 플라즈마 개질 시스템에서 수소 생산 및 CO 산화반응에 관한 연구)

  • Hong, Suck Joo;Lim, Mun Sup;Chun, Young Nam
    • Korean Chemical Engineering Research
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    • v.45 no.6
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    • pp.656-662
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    • 2007
  • Fuel reformer using plasma and shift reactor for CO oxidation were designed and manufactured as $H_2$ supply device to operate a polymer electrolyte membrane fuel cell (PEMFC). $H_2$ selectivity was increased by non-thermal plasma reformer using GlidArc discharge with Ni catalyst simultaneously. Shift reactor was consisted of steam generator, low temperature shifter, high temperature shifter and preferential oxidation reactor. Parametric screening studies of fuel reformer were conducted, in which there were the variations of the catalyst temperature, gas component ratio, total gas ratio and input power. and parametric screening studies of shift reactor were conducted, in which there were the variations of the air flow rate, stema flow rate and temperature. When the $O_2/C$ ratio was 0.64, total gas flow rate was 14.2 l/min, catalytic reactor temperature was $672^{\circ}C$ and input power 1.1 kJ/L, the production of $H_2$ was maximized 41.1%. And $CH_4$ conversion rate, $H_2$ yield and reformer energy density were 88.7%, 54% and 35.2% respectively. When the $O_2/C$ ratio was 0.3 in the PrOx reactor, steam flow ratio was 2.8 in the HTS, and temperature were 475, 314, 260, $235^{\circ}C$ in the HTS, LTS, PrOx, the conversion of CO was optimized conditions of shift reactor using simulated reformate gas. Preheat time of the reactor using plasma was 30 min, component of reformed gas from shift reactor were $H_2$ 38%, CO<10 ppm, $N_2$ 36%, $CO_2$ 21% and $CH_4$ 4%.

Utilization of $CO_2$ Influenced by Windbreak in an Elevated Production System for Strawberry (딸기 고설재배시설에서의 이산화탄소 농도 유지를 위한 방풍막 설치 효과)

  • Kim, Y.-H.;Lee, I.-B.;Chun, Chang-Hoo;Hwang, H.-S.;Hong, S.-W.;Seo, I.-H.;Yoo, J.-I.;Bitog, Jessie P.;Kwon, K.-S.
    • Journal of Bio-Environment Control
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    • v.18 no.1
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    • pp.29-39
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    • 2009
  • The influence of windbreak to minimize the ventilation velocity near the plant canopy of a greenhouse strawberry was thoroughly investigated using computational fluid dynamics (CFD) technology. Windbreaks were constructed surrounding the plant canopy to control ventilation and maintain the concentration of the supplied $CO_2$ from the soil surface close to the strawberry plants. The influence of no windbreak, 0.15 m and 0.30 m height windbreaks with varied air velocity of 0.5, 1.0 and 1.5 m/s were simulated in the study. The concentrations of supplied $CO_2$ within the plant canopy of were measured. To simplify the model, plants were not included in the final model. Considering 1.0m/s wind velocity which is the normal wind velocity of greenhouses, the concentrations of $CO_2$ were approximately 420, 580 and 653 ppm ($1{\times}10^{-9}kg/m^3$) for no windbreak, 0.15 and 0.30 m windbreak height, respectively. Considering that the maximum concentration of $CO_2$ for the strawberry plants was around 600-800 ppm, the 0.30 m windbreak height is highly recommended. This study revealed that the windbreak was very effective in preserving $CO_2$ gas within the plant canopy. More so, the study also proved that the CFD technique can be used to determine the concentration of $CO_2$ within the plant canopy for the plants consumption at any designed condition. For an in-depth application of this study, the plants as well as the different conditions for $CO_2$ utilization, etc. should be considered.

The Effect of Constraint-Induced Movement Therapy(CIMT) With Cognitive-Perceptual Training on Upper Extremity Function of Stroke Patients With Mild Cognitive Impairment (경도 인지손상을 가진 뇌졸중 환자의 상지 기능에 미치는 강제유도운동치료(CIMT)와 인지-지각 훈련의 병행 효과)

  • Kim, Hun-Ju;Shin, Joong-Il;Kam, Kyung-Yoon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.12 no.12
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    • pp.5684-5691
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    • 2011
  • The purpose of this study is to examine effects of constraint-induced movement therapy(CIMT) and/or cognitive-perceptual training(CPT) on the change of hand function in cerebrovascular accident(CVA) patients and to evaluate the change in the amount and quality of use of the affected upper extremity in performing daily living tasks. The subjects of study were 10 patients who had been under rehabilitation for more than three months after CVA onset. They were all determined as mild cognition impairment according to NCSE or MVPT test. For CIMT group, to restrict the movement of the unaffected hand the subjects had been worn modified resting arm-splint in daytime for 4 weeks. For CIMT+CPT group, the subjects were performed CPT with CIMT and control group had been under conventional occupational therapy for the same period. CIMT+CPT group showed significant improvement in simulated feeding, lifting large light objects, and lifting large heavy objects of Jebsen-Taylor Hand Function Test. CIMT group also showed significant improvement compared with control group. The mean changes of the amount of use(AOU) of the affected arm had a statistically significant difference among groups (p<.05). While CIMT+CPT group had the biggest change in the quality of movement(QOM) of upper extremity of the affected side, CTL group showed the smallest change. Both CIMT and CIMT+CPT groups had statistically significant difference in the change in the quality of movement in upper extremity of affected side with CTL group(p<.05), but there was not significant difference between CIMT group and CIMT+CPT group. CIMT performed to the patients of stroke, with mild impairment in cognitive perceptual abilities showed the improvement in hand movement and AOU and QOM of upper extremity in the affected side and the combination of CIMT with CPT showed synergic effects.

Change in Potential Productivity of Rice around Lake Juam Due to Construction of Dam by SIMRIW (벼 생장모형 SIMRIW를 이용한 주암호 건설에 따른 주변지역의 벼 잠재생산성 변이 추정)

  • 임준택;윤진일;권병선
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.42 no.6
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    • pp.729-738
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    • 1997
  • To estimate the change in rice productivity around lake Juam due to construction of artificial lake, growth, yield components and yield of rice were measured at different locations around lake Juam for three years from 1994 to 1996. Automated weather stations(AWS) were installed nearby the experimental paddy fields, and daily maximum, average and minimum temperature, solar radiation, relative humidity, and precipitation were measured for the whole growing period of rice. Plant height, number of tillers, leaf area and shoot dry weight per hill were observed from 8 to 10 times in the interval of 7 days after transplanting. Yield and yield components of rice were observed at the harvest time. Simulation model of rice productivity used in the study was SIMRIW developed by Horie. The observed data of rice at 5 locations in 1994, 3 locations in 1995 and 4 locations in 1996 were inputted in the model to estimate the unknown parameters. Comparisons between observed and predicted values of shoot dry weights, leaf area indices, and rough rice yield were fairly well, so that SIMRIW appeared to predict relatively well the variations in productivity due to variations of climatic factors in the habitat. Climatic elements prior to as well as posterior to dam construction were generated at six locatons around lake Juam for thirty years by the method of Pickering et al. Climatic elements simulated in the study were daily maximum and minimum temperature, and amount of daily solar radiation. The change in rice productivity around lake Juam due to dam construction were estimated by inputting the generated climatic elements into SIMRIW. Average daily maximum temperature after dam construction appeared to be more or less lower than that before dam construction, while average daily minimum temperature became higher after dam construction. Average amount of daily solar radiation became lower with 0.9 MJ $d^{-1}$ after dam construction. As a result of simulation, the average productivity of habitats around lake Juam decreased about 5.6% by the construction of dam.

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