• 대한간호학회지
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• 제52권1호
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• pp.4-23
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• 2022

Purpose: The aim of this study was to evaluate the effect of auriculotherapy on musculoskeletal pain in adults. Methods: A total of 885 studies were retrieved from nine databases (PubMed, Scopus, CINAHL, Web of Science, Ovid Medline, Cochrane Library, RISS, KMbase, and KISS). Sixteen studies were selected for meta-analysis, which satisfied the inclusion criteria and the evaluation of risk of bias. Demographic data, auriculotherapy types, intervention characteristics, auricular points, and outcomes related to pain (subjective pain scale, and amount of analgesic) were extracted from all included studies. The effect size of auriculotherapy was analyzed through comprehensive meta analysis 3.0, and the presence of publication bias was analyzed through a funnel plot and Egger's regression. Results: The results of the meta-analysis (n = 16) revealed that the auriculotherapy was significantly superior to the control group on present pain in adults (Hedges' g = - 0.35, 95% Confidence Interval [CI] = - 0.55~- 0.15). According to the results of subgroup analysis, the effect size of auricular acupuncture therapy (Hedges' g = 0.45, 95% CI = - 0.75~- 0.15) was higher than the auricular acupuncture (Hedges' g = 0.27, 95% CI = - 0.53~0.00): the longer the intervention period, the greater the effect size. Conclusion: In this study, auriculotherapy demonstrates a significant reduction in musculoskeletal pain in adults. Therefore, it is necessary to refine the curriculum to include auriculotherapy as a nursing intervention to relieve musculoskeletal pain in adults and encourage its use in clinical settings.

• 환경정책연구
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• 제13권1호
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• pp.25-47
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• 2014

여기에서는 CEP-CFP 간의 관련성 관련 연구들을 종합하고 체계적으로 분석해 보고 서로 다른 맥락에서 이루어진 연구들을 비교하여 조절변수를 찾아내기 위해 메타분석을 시도하였다. 연구결과를 보면 첫째, 다섯 가지 CEP척도는 모두 CFP척도와 양의 관련성을 보였으나 환경투자 척도는 유의하지 않았다. CFP척도는 모두 CEP와 정의 상관을 보여 주었다. 둘째, CEP-CFP 간의 관련성을 설명하는 조절변인을 확인하기 위한 메타분석의 결과는 측정방식과 분석(추정)모형은 CEP-CFP 간의 관계를 조절하였다. 반면에 출판년도, 시차변수의 포함 여부, 표본 크기, 학술지 종류는 조절변수로서의 역할을 수행하지 않았다.

• 임상간호연구
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• 제29권3호
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• pp.296-311
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• 2023

Purpose: This study aimed to identify factors related to the workload of intensive care unit nurses through a systematic literature review and meta-analysis to provide basic data to explore the direction of development of nursing staffing standards. Methods: This study involved quantitative studies about nurses working in intensive care units related to nursing workload published in English or Korean since 2000. Search terms included 'intensive care unit', 'nursing workload', and their variations. Databases such as RISS, DBpia, MEDLINE(PubMed), CINAHL, PsycINFO, and Web of Science were utilized. Quality assessment was conducted using the Joanna Briggs Institute's Critical Appraisal Checklist for Analytical Cross-Sectional Studies. JAMOVI software facilitated the analysis of effect sizes, employing a meta-analysis approach for 7 studies with correlational or regression data. Results: From 16 studies on the workload of intensive care unit nurses, a total of 20 patient and nurse-related factors were identified. Patient-related factors included severity of illness, length of stay, and age. Meta-analysis was conducted for three patient-related factors: age, severity of illness measured by SAPS 3, and length of stay. Only severity of illness measured by SAPS 3 was significantly associated with nurse workload (Zr=0.16, p<.001, 95% CI=0.09-0.24). Conclusion: In previous studies, the characteristics of intensive care units and patients varied across studies, and a variety of scales for measuring workload and severity of illness were also used. Sustained research reflecting domestic intensive care unit work environments and assessing the workload of intensive care unit nurses should be imperative.

• Journal of Korean Neurosurgical Society
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• 제62권4호
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• pp.389-397
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• 2019

Objective : Mechanical thrombectomies with balloon-guide catheters (BGC) are thought to improve successful recanalization rates and to decrease the incidence of distal emboli compared to thrombectomies without BGC. We aimed to assess the effects of BGC on the outcomes of mechanical thrombectomy in acute ischemic strokes. Methods : Studies from PubMed, EMBASE, and the Cochrane library database from January 2010 to February 2018 were reviewed. Random effect model for meta-analysis was used. Analyses such as meta-regression and the "trim-and-fill" method were additionally carried out. Results : A total of seven articles involving 2223 patients were analyzed. Mechanical thrombectomy with BGC was associated with higher rates of successful recanalization (odds ratio [OR], 1.632; 95% confidence interval [CI], 1.293-2.059). BGC did not significantly decrease distal emboli, both before (OR, 0.404; 95% CI, 0.108-1.505) and after correcting for bias (adjusted OR, 1.165; 95% CI, 0.310-4.382). Good outcomes were observed more frequently in the BGC group (OR, 1.886; 95% CI, 1.564-2.273). Symptomatic intracranial hemorrhage and mortality did not differ significantly with BGC use. Conclusion : Our meta-analysis demonstrates that BGC enhance recanalization rates. However, BGC use did not decrease distal emboli after mechanical thrombectomies. This should be interpreted with caution due to possible publication bias and heterogeneity. Additional meta-analyses based on individual patient data are needed to clarify the role of BGC in mechanical thrombectomies.

• 대한통합의학회지
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• 제7권3호
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• pp.71-83
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• 2019

Purpose: This meta-analysis aimed to analyze to the effects of aquatic exercise programs in children with cerebral palsy and identify directions for future research. Methods: A systematic search based on the PRISMA guidelines was undertaken for studies conducted between 2006 and 2018 on aquatic exercise programs in children with cerebral palsy. A total of 10 studies were selected according to the inclusion criteria. The methodological quality was assessed using the Risk of Bias Tool for Randomized Controlled Trials (RoB) and Risk-of-Bias Assessment Tool for Non-randomized Studies (RoBANS). A meta-analysis software (CMA 3.0) was used to calculate the mean effect size, effect size by intervention (Halliwick and Watsu Aquatic methods), and effect size by outcome. Results: The mean effect size was 0.457. The effect size by intervention was largest for the Halliwick method, followed by the Watsu method. The effect size by outcome was largest for range of motion, followed by the gross motor function measure, the Pediatric Berg Balance Scale, and the Modified Ashworth Scale. Meta-regression analysis showed effect size increased when sample size, number of sessions, and length of sessions increased. Conclusion: The results show that aquatic exercise programs have a positive effect on children with cerebral palsy. Therefore, it is necessary to develop a guideline that recommends the appropriate intervention and the identifies the direction of future studies on aquatic exercise programs.

• Journal of the Korean Data and Information Science Society
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• 제21권4호
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• pp.651-667
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• 2010

항-고지혈 효과에 대한 연관 측도로 효과 인자를 고려한 헤지의 표준화된 평균차를 이용하였다. 고정효과모형을 적용하여 메타분석을 시행하였다. 그 결과 변의 콜레스테롤 농도와 총 콜레스테롤 농도 그리고 트리글리세리드 농도에서 통계적으로 유의한 감소를 보였으며, 고농도지단백 콜레스테롤 농도에서 통계적으로 유의한 증가를 보였다. 다음으로 연구 간 분산을 고려하지 않고 고정효과모형을 가정하여 분석한 모든 변수들에 대해 동질성 검정을 실행하여 연구 간의 이질성의 존재를 확인하였다. 그 결과 신장의 무게, 간의 무게, 고농도지단백 콜레스테롤, 저농도지단백 콜레스테롤, 총 콜레스테롤, 트리글리세리드 농도에서 동질성을 만족하지 않았다.

• Journal of Veterinary Science
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• 제23권1호
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• pp.13.1-13.12
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• 2022

Background: Toxoplasma gondii can infect humans and most animals and has a very high infection rate worldwide, including in China. The number of people infected with T. gondii in China increases with the number of cats. Objectives: We investigated the seropositive rate of T. gondii in cats over the last five years and analyzed the risk factors via meta-analysis. Methods: We retrieved 20 studies, with a total of 5,158 cats, published between 2016 and 2020, used the DerSimonian-Laird model and calculated seroprevalence estimates with the variance stabilizing double arcsine transformation. Results: The overall seroprevalence rate after sinusoidal conversion was 19.9% (95% confidence interval [CI], 15.9-23.9; 966/5,158), lower than the domestic report from 1995 to 2015 (24.5%, 95% CI, 20.1-29.0). There was substantial heterogeneity among studies (χ² = 262.32; p < 0.001; I² = 64.6%). Regression analysis of possible heterogeneous causes and subgroup analysis showed that age and whether cats were stray or not have a significant effect on the seropositive rate. Conclusions: Articles published in recent five years suggest that the seroprevalence estimates of Toxoplasma gondii in cats has decreased. Cats, as the final host of T. gondii, are an important cause of the spread of the parasite, and this is an important concern for public health.

• 디지털산업정보학회논문지
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• 제13권4호
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• pp.125-139
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• 2017

In this paper, we developed a framework to detect and predict insider information leakage by collecting and restoring network traffic. For automated behavior analysis, many meta information and behavior information obtained using network traffic collection are used as machine learning features. By these features, we created and learned behavior model, network model and protocol-specific models. In addition, the ensemble model was developed by digitizing and summing the results of various models. We developed a function to present information leakage candidates and view meta information and behavior information from various perspectives using the visual analysis. This supports to rule-based threat detection and machine learning based threat detection. In the future, we plan to make an ensemble model that applies a regression model to the results of the models, and plan to develop a model with deep learning technology.

• 한국산학기술학회논문지
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• 제17권11호
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• pp.271-284
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• 2016

본 연구는 임부의 산전우울에 대한 인지행동치료 중재의 효과를 검증하기 위해 수행된 체계적 문헌고찰 및 메타분석 연구이다. 데이터베이스는 CINAHL, PubMed, EMBASE 및 Koreamed, 국회도서관, 한국학술정보(Korean studies Information Service System, KISS), 한국의학논문데이터베이스 등 국내외 domain을 활용하였다. 검색은 ((Perinatal OR Antenatal OR Antepartum OR Pregnant) AND Depression) AND Women AND (CBT OR (Cognitive behavioral AND (Therapy OR Treatment)))와 '산전우울', '임부', '인지행동치료' 등의 검색어로 2016년 5월까지 출판된 문헌을 검토하였다. 분석은 R을 이용한 임의효과모형을 적용하여 산전우울과 불안의 효과크기를 각각 산출하였으며, 효과크기의 이질성을 검증하기위해 메타 ANOVA를 활용하여 조절효과분석을 실시하였다. 그리고 funnel plot, Egger's regression test, fail-safe N, trim-and-fill 분석을 활용한 출간오류분석과 민감성 분석을 실시하여 전체 연구 결과의 타당성을 검증하였다. 연구결과 총 180편의 문헌이 검색되었으며, 선택배제기준에 따라 최종적으로는 clinical trials 16편을 분석하였다. 분석에 포함된 개별문헌은 Scottish Intercollegiate Guideline Network (SIGN)의 checklist를 통해 비뚤림 위험을 평가하였으며, 대체로 비뚤림 위험은 낮았다. 연구결과 본 연구에서 중재의 산전우울에 대한 효과크기는 Hedges' g=-0.55(95% CI: -0.76~-0.33)로 통계적으로 유의하게 낮았으며, 불안에 대한 효과크기는 Hedges' g=-0.20(95% CI: -0.48~-0.08)이었으나, 통계적으로 유의한 차이는 없었다. 문헌의 이질성, 출판오류의 위험성 등은 낮았다. 본 메타분석결과에 의하면 인지행동치료는 임신부의 산전우울 증세 완화에 보통 정도의 효과가 있음이 밝혀졌다.

• Journal of Preventive Medicine and Public Health
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• 제49권6호
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• pp.367-375
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• 2016

Objectives: The established theory that breast density is an independent predictor of breast cancer risk is based on studies targeting white women in the West. More Asian women than Western women have dense breasts, but the incidence of breast cancer is lower among Asian women. This meta-analysis investigated the association between breast density in mammography and breast cancer risk in Asian women. Methods: PubMed and Scopus were searched, and the final date of publication was set as December 31, 2015. The effect size in each article was calculated using the interval-collapse method. Summary effect sizes (sESs) and 95% confidence intervals (CIs) were calculated by conducting a meta-analysis applying a random effect model. To investigate the dose-response relationship, random effect dose-response meta-regression (RE-DRMR) was conducted. Results: Six analytical epidemiology studies in total were selected, including one cohort study and five case-control studies. A total of 17 datasets were constructed by type of breast density index and menopausal status. In analyzing the subgroups of premenopausal vs. postmenopausal women, the percent density (PD) index was confirmed to be associated with a significantly elevated risk for breast cancer (sES, 2.21; 95% CI, 1.52 to 3.21; $I^2=50.0%$). The RE-DRMR results showed that the risk of breast cancer increased 1.73 times for each 25% increase in PD in postmenopausal women (95% CI, 1.20 to 2.47). Conclusions: In Asian women, breast cancer risk increased with breast density measured using the PD index, regardless of menopausal status. We propose the further development of a breast cancer risk prediction model based on the application of PD in Asian women.