• 대한건축학회논문집:계획계
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• 제35권9호
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• pp.101-108
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• 2019

Chinese ethnic minorities are inheriting their own traditions based on thousands of years of community life. Yunnan province in china is a castle in which many ethnic minorities have been living on the basis of various natural environments. Their traditional village can be regarded as a place reflecting minorities' thousands year of history and culture, and elements of positive social spaces are seen from the old village. Streets and places of the village are accumulated as images for residents. Based on their imagination-concept, sketch maps, reflecting residents' cognitive perception were collected. Analysis of 21 sketch maps shows that architectural elements, forming a unique landscape and community life contribute to establish a unity of one nation. the oldest tree in the village has a strong specificity as a place with the belief that the tree protects all residents in the village. Space in the head of the residents and Social spaces, embedded in the memories of the residents living in the community continued organically and the roads of the village showed clear recognition. Following this, the analysis methodology of social spaces and sketch will be examined in depth.

• Asian-Australasian Journal of Animal Sciences
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• 제33권4호
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• pp.531-538
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• 2020

Objective: Evidence from previous reports indicates that pig domestication in East Asia mainly occurred in the Mekong region and the middle and downstream regions of the Yangtze River. Further research identified two new origin centers for domestic pigs in the Tibetan Plateau and the islands of Southeast Asia. However, due to the small sample size of Tibetan pigs, details of the origin and spread of Tibetan pigs has not yet been established. Methods: We analyzed mitochondrial DNA control region (D-loop) variation in 1,201 individuals from nine Tibetan pig populations across five provinces. Comprehensive Tibetan pig samples were taken to perform the most detailed analysis of Tibetan pigs to date. Results: The result indicate that Rkaze pigs had the lowest level of diversity, while Changdu pigs had the highest diversity. Interestingly, these two populations were both in the Tibetan Plateau area. If we calculate diversity in terms of each province, the Tibetan Plateau area had the lowest diversity, while the Chinese province of Gansu had the highest diversity. Diversity gradient analysis of major haplotypes suggested three domestication centers of Tibetan pigs in the Tibetan Plateau and the Chinese provinces of Gansu and Yunnan. Conclusion: We found two new domestication centers for Tibetan pigs. One is in the Chinese province of Gansu, which lies in the upstream region of the Yellow River, and the other is in the Chinese province of Yunnan.

• 한국산업정보학회:학술대회논문집
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• 한국산업정보학회 2007년도 춘계학술대회
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• pp.181-188
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• 2007

In this paper, the management thoughts of The network-manufacture based on virtual-agile organization is Brief summarized, then an explanation had been made about the virtual circulation economy patterns paradigm, which is integrated the virtual-agile manufacture and circulation economy theory, the critical content of this paradigm, at last we recognized the virtual-agile organization pattern circulation economy is one important trend of the network-manufacture development in the future.

• Journal of Microbiology
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• 제45권2호
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• pp.105-112
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• 2007

The objective of this study was to analyze the phylogenetic composition of bacterial community in the soil of an earth-cave (Niu Cave) using a culture-independent molecular approach. 16S rRNA genes were amplified directly from soil DNA with universally conserved and Bacteria-specific rRNA gene primers and cloned. The clone library was screened by restriction fragment length polymorphism (RFLP), and representative rRNA gene sequences were determined. A total of 115 bacterial sequence types were found in 190 analyzed clones. Phylogenetic sequence analyses revealed novel 16S rRNA gene sequence types and a high diversity of putative bacterial community. Members of these bacteria included Proteobacteria (42.6%), Acidobacteria (18.6%), Planctomycetes (9.0 %), Chloroflexi (Green nonsulfur bacteria, 7.5%), Bacteroidetes (2.1%), Gemmatimonadetes (2.7%), Nitrospirae (8.0%), Actinobacteria (High G+C Gram-positive bacteria, 6.4%) and candidate divisions (including the OP3, GN08, and SBR1093, 3.2%). Thirty-five clones were affiliated with bacteria that were related to nitrogen, sulfur, iron or manganese cycles. The comparison of the present data with the data obtained previously from caves based on 16S rRNA gene analysis revealed similarities in the bacterial community components, especially in the high abundance of Proteobacteria and Acidobacteria. Furthermore, this study provided the novel evidence for presence of Gemmatimonadetes, Nitrosomonadales, Oceanospirillales, and Rubrobacterales in a karstic hypogean environment.

• Asian Pacific Journal of Cancer Prevention
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• 제14권11호
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• pp.6649-6651
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• 2013

Background: Mdm2 binds to the amino-terminus of p53 to induce its degradation and a single nucleotide polymorphism in the MDM2 promoter region (T309G) has been reported to increase the risk of several carcinomas, such as gastric cancer. However, the results of published studies to analyze the association between MDM2 T309G and gastric cancer havve often conflicted. Methods: To better illustrate the filiation between MDM2 T309G and gastric cancer, we performed a meta-analysis. Odds ratios (ORs) and 95% confidence intervals (CIs) were used to evaluate the strength of the relationship. The pooled ORs were performed for 4 models, additive, recessive, co-dominant model, and dominant. Results: Nine published case-control studies including 3,225 gastric cancer cases and 4,118 controls were identified. The MDM2 T309G polymorphism was associated with a significantly increased risk of gastric cancer risk when all studies were pooled into the meta-analysis (GG versus TT, OR=1.57; 95%CI=1.57-2.12; p=0.003) and GG versus GT/TT, OR=1.52; 95%CI=1.217-1.90; p<0.001). Furthermore, Egger's test did not show any evidence of publication bias (P = 0.608 for GG versus TT). Conclusion: Our results suggest that the MDM2 T309G polymorphism is indeed associated with a significantly increased risk of gastric cancer.

• Animal Systematics, Evolution and Diversity
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• 제29권2호
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• pp.179-183
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• 2013

The perlid stonefly Brahmana flavomarginata Wu, originally described from China from the male adult, is described using reared male and female adults and nymphs from Vietnam. The male adult of B. flavomarginata is distinguished from its congeners by the blackish-brown body color and distinct head marking, hemitergal triangular chitin plates, and a median semicircular smooth subgenital plate (hammer) on the abdominal sternum IX. The female adult has a large and round subgenital plate which extends to the posterior margin of the abdominal sternum X. The nymph can be distinguished by the relatively small compound eyes and the body covered by many long stout setae and short golden brown hair-like setae. This species is known in southwestern China (Yunnan Province) and northern Vietnam (Lao Cai Province, Cao Bang Province).

• Asian Pacific Journal of Cancer Prevention
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• 제15권15호
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• pp.6009-6014
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• 2014

Aims: To investigate changes in cellular immune function of patients with lung cancer before and after cytokine-induced killer (CIK) cell therapy and to identify variation effects on overall survival (OS) and progression-free survival (PFS). Materials and Methods:A total of 943 lung cancer patients with immune dysfunction were recruited from January 2002 to January 2010, 532 being allocated to conventional therapy and 411 to CIK therapy after a standard treatment according to the NCCN Clinical Practice Guidelines. All the patients were investigated for cellular immune function before and after therapy every three months. and clinical prognostic outcomes were analyzed. Results: After six courses of treatment, immune function was much improved in patients receiving CIK cells therapy as compared to controls. The percentages of recurrence and/or metastases for patients undergoing CIK cell therapy was 56.2% and 49.1% respectively but 78.6% and 70.3% among controls (p<0.001). The median OS times for CIK cell therapy and control groups were 48 and 36 months respectively. The OS rates at 12, 36, 60, 84 months in CIK treated patients were 97.8%, 66.9%, 27.7%, and 4.1% while they were 92.3%, 44.5%, 9.2%, and 1.5% in controls. OS and PFS were significantly different by log rank test between the two groups and across the three immune improvement classes. Conclusions: The immune function of lung cancer patients was improved by CIK cell therapy, associated with an increase in the OS rate and extension of the time to recurrence and/or metastasis.

• Animal cells and systems
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• 제2권4호
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• pp.411-414
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• 1998

One novel species, Phaeacius yunnanensis n. sp. and three species new to China, Brettus albolimbattus, Hyllus lacertosus and Ptocasius kinhi of the jumping spider.belonging to the family Salticidae, are described based on the materials collected from Yunnan Province, China. The new species is similar to Phaecius lancerarius, but can be distinguished by secondary conductor covers on the emblus. That of the latter below the emblous, retro1aterial tibial apophysis, is much more slender and with an abdominal pattern.

• Entomological Research
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• 제48권5호
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• pp.348-353
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• 2018

A new whitefly species, Pealius yunnanensissp. nov., collected from Mengzi, Caoba village (Yunnan, China) on Ficus microcarpa Linn. f. (Urticales: Moraceae), is described with morphology, line illustrations, photographs and scanning electron microscope images. In addition, a checklist of Chinese species of Pealius is provided and all Pealius species recorded from Ficus around the world are listed. Specimens have been deposited in the Insect Collection of Zhejiang Agriculture & Forestry University (ZAFU), Lin'an, China.

• The Korean Journal of Physiology and Pharmacology
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• 제25권2호
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• pp.97-109
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• 2021

Neonatal hypoxia/ischemia (H/I), injures white matter, results in neuronal loss, disturbs myelin formation, and neural network development. Neuroinflammation and oxidative stress have been reported in neonatal hypoxic brain injuries. We investigated whether Paeoniflorin treatment reduced H/I-induced inflammation and oxidative stress and improved white matter integrity in a neonatal rodent model. Seven-day old Sprague-Dawley pups were exposed to H/I. Paeoniflorin (6.25, 12.5, or 25 mg/kg body weight) was administered every day via oral gavage from postpartum day 3 (P3) to P14, and an hour before induction of H/I. Pups were sacrificed 24 h (P8) and 72 h (P10) following H/I. Paeoniflorin reduced the apoptosis of neurons and attenuated cerebral infarct volume. Elevated expression of cleaved caspase-3 and Bad were regulated. Paeoniflorin decreased oxidative stress by lowering levels of malondialdehyde and reactive oxygen species generation and while, and it enhanced glutathione content. Microglial activation and the TLR4/NF-κB signaling were significantly down-regulated. The degree of inflammatory mediators (interleukin 1β and tumor necrosis factor-α) were reduced. Paeoniflorin markedly prevented white matter injury via improving expression of myelin binding protein and increasing O1-positive olidgodendrocyte and O4-positive oligodendrocyte counts. The present investigation demonstrates the potent protective efficiency of paeoniflorin supplementation against H/I-induced brain injury by effectually preventing neuronal loss, microglial activation, and white matter injury via reducing oxidative stress and inflammatory pathways.