• Title/Summary/Keyword: Young patients

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Comparison of Presentation and Clinical Outcome between Children and Young Adults with Differentiated Thyroid Cancer

  • Wang, Jian-Tao;Huang, Rui;Kuang, An-Ren
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.17
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    • pp.7271-7275
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    • 2014
  • Background: The aim of the present study was to evaluate the presentation, clinical course and outcome between children and young adults with differentiated thyroid cancer (DTC) treated in our hospital. Materials and Methods: The medical records of 145 patients with DTC who underwent surgery followed by radioiodine and thyroid hormone (TSH) suppression were retrospectively reviewed. The follow up was between January 2006 and June 2012. These patients consisted of 38 children (age${\leq}18y$) and 107 young adult patients (age${\leq}30y$). The clinical characteristics and outcome were analyzed and compared, and the progression-free survival (PFS) was evaluated using the Kaplan-Meier method. Results: At initial diagnosis, a greater degree of extra thyroidal extension was found in children than adults patients (p<0.001). However, there was no significant difference between the two groups with regard to the tumor size and the presence of lymph node or distant metastasis (p=0.172, p=0.050 and p=0.068, respectively). The extent of surgery and the cumulative or mean dose of radioiodine were similar in both groups. During the follow up, the overall survival rate was 100% for both groups, and the PFS rate was similar in children and in young adults group (log rank test, ${\chi}^2$=0.126, p=0.723). Conclusions: In comparison to the young adult patients, DTC in children presents with more aggressive behavior, but outcomes are similar between the two groups after the intensive management of surgery followed by radioiodine and TSH suppression therapy.

Study on Cerebral Blood Flow in In-Young(ST9) after Treatment on Chronic Daily Headache Patients (만성두통 환자에서 한방 치료 후 인영혈 부위의 뇌혈류에 대한 연구)

  • Lee, Chung-Sik;Park, Bo-Ra;Park, In-Suk;Kim, Ji-Hwon;Lee, Sang-Eon;Lim, Jin-Young;Lyu, Yeoung-Su;Kang, Hyung-Won;Kim, Tae-Heon
    • Journal of Oriental Neuropsychiatry
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    • v.20 no.1
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    • pp.199-214
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    • 2009
  • Objectives : This study was performed to change of blood flow in In-Young(ST9) after treatment on chronic daily headache patients. Methods : Monitoring of TCD was examined in 10' s chronic daily headache patients before and after treatment. Mean velocity flow, systolic velocity and pulsatility index were analyzed from TCD at In-Young(ST9). The patients was laid for 20 minutes before treatment and also for treatment. Results : The results showed a significant(p<0.05: Paired T-test) decrease in mean velocity flow and systolic velocity. but there were no significant differences in pulsatility index. Conclusions : These results suggest that there were significant change on blood flow in In-young of chronic daily headache patients.

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Clinical Aanalysis of Airway Trauma (외상성 기도 손상의 임상적 고찰)

  • Cho, Hyun-Min;Kim, Young-Jin;Ryu, Han-Young;Hwang, Jung-Joo
    • Journal of Trauma and Injury
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    • v.24 no.1
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    • pp.7-11
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    • 2011
  • Purpose: Traumatic airway injuries have high rates of mortality and morbidity. Thus, we evaluated the clinical results of trauma-related airway-injury patients. Methods: A clinical analysis was performed for patients with airway trauma who were admitted and treated at the Department of Thoracic and Cardiovascular Surgery, Konyang University Hospital from Dec. 2002 to Dec. 2009. Results: Sixteen patients were admitted and treated. Fourteen patients were male, and the ages of the patients ranged from 16 to 75 years. Six cases were penetrating injuries, 4 were traffic-accident injuries. 3 were fall injuries, and. 3 were other blunt trauma injuries. Anato- mic injuries included 14 trachea cases (87.5%), 1 Rt. main bronchus (6.25%), and 1 Lt. main bronchus cases (6.25%). Diagnosis was made by using computed tomography and bronchoscopy. Five patients were treated with an explothoracotomy, and 7 underwent neck exploration with primary repair. Three patients simply needed conservative management, and 1 patient was treated with a closed thoracostomy. The post-operative mortality rate was 6.25 % (1 patient). Conclusion: Airway trauma is dangerous and should be treated as an emergency, so a high index of suspicion is essential for rapid diagnosis and successful surgical intervention in patients with airway injuries.

Rotavirus Gastroenteritis (Rotavirus성 위장염)

  • Kang, Jeong-Oak;Park, Seung-Hahm;Kim, Ki-Hong;Lee, Keun-Soo
    • The Journal of the Korean Society for Microbiology
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    • v.17 no.1
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    • pp.15-19
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    • 1982
  • Fifty two infants and young children hospitalized in the pediatric department of Hanyang University Hospital with acute gastroenteritis from February through April 1982 were examined for the evidence of infection with rotavirus by electron microscopic technique and enzyme-linked immunosorbent assay(ELISA). Of 52 patients examined, rotaviruses were detected in stools of 11 patients(21%) by EM technique and 16 patients(31%) by ELISA. But there was no significant statistical difference between the two methods(Z=1.2<2). During the study period, rotaviruses were detected in stools of 6(38%) of 16 patients in February, 10(30%) of 33 patients in March, and none of 3 patients in April. The age of the 16 patients who shed the rotaviruses in their stools ranged from 3 months to 6 years, and 12 patients(75%) were between 6 and 24 months. Our study suggests that the rotaviral gastroenteritis of infants and young children in Korea might have similar frequency, seasonal variation, and age distribution with other countries in temperate zone.

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Clinical Evaluation of Patients Intoxicated by a Gas Leak at an Underground Shopping Center - Carbon Monoxide Poisoning - (지하상가 가스누출 사고 환자들에 대한 임상적 고찰 - 일산화탄소 중독 -)

  • Ahn, Ji-Young;Ko, Young-Gil
    • Journal of The Korean Society of Clinical Toxicology
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    • v.4 no.2
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    • pp.122-127
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    • 2006
  • Purpose: It is not easy to detect carbon monoxide (CO) leakage, and CO-intoxicated patients do not show a specific set of symptoms. The aims of this study are to clinically evaluate patients with CO gas intoxication from a CO leak at an underground shopping center, and to discuss the establishment of a disaster prevention plan. Methods: A total of 51 patients intoxicated by CO gas exposure in a gas disaster at a underground shopping center in Seoul on September 8, 2006 were enrolled in this study, and the patients' medical records were retrospectively reviewed. Results: The mean patient age was $29.4{\pm}6.3$. The initial mean COHb level was $14.98{\pm}6.97%$. The number of patients with COHb greater than 25% was three, and six patients experienced a syncopal attack. Only one patient-was treated with hyperbaric oxygen therapy. However, none of the patients complained of severe neurologic or cardiovascular symptoms. Conclusion: The symptoms of CO intoxication are non-specific and difficult to define, and the detection of CO leak-age is difficult. Thus, workplaces should be equipped with leakage sensors and automatic alarm systems and should have develop disaster prevention plans.

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The Surgical Treatment of Three Young Chronic Subdural Hematoma Patients with Different Causes

  • Hou, Kun;Li, Chen G.;Zhang, Yang;Zhu, Bo X.
    • Journal of Korean Neurosurgical Society
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    • v.55 no.4
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    • pp.218-221
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    • 2014
  • Chronic subdural hematoma (CSDH), which rarely happens in the young, is thought to be a disease of the elderly. Whereas unspecific symptoms and insidious onset in juveniles and young adults, as a result of its relative low morbidity, CSDH is usually neglected even undertreated in the young. Through the three cases and review of the current literature on this subject, we tried to illustrate the clinical and etiopathological characteristics of this entity and find out the most appropriate treatment strategy. We report three young CSDH patients with different but similar symptoms. The present histories, tests and examinations revealed different predisposing factors accounting for the genesis of CSDH. Their preoperative symptoms were all resolved with burr hole and drainage operation. Juveniles and young adults suffering from CSDH differ from that of their elderly counterparts in their clinical and etiopathological characteristics. Although trauma is the most important risk factor in young and old CSDH patients, some other predisposing factors may exist. Burr hole and drainage surgery could resolve the problem most of the time. But further tests and examinations even specific management should be made in some cases.

Use of Midazolam Intranasal Spray for Dental Treatment of Autism Patients (자폐증 환자의 행동조절을 위한 Midazolam Intranasal Spray 사용사례)

  • Song, Young-Gyun;Lee, Suk Young;Kim, Seung-Oh
    • Journal of The Korean Dental Society of Anesthesiology
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    • v.12 no.4
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    • pp.223-227
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    • 2012
  • Autism patients in general have bad oral hygiene. It is hard for autism patients to get dental treatment as poor communication. Therefore, they may have to be treated by deep sedation or general anesthesia in numerous cases. However, this process requires induction with mask, so it is not easy to do for disobliging autism patient. Midazolam is a water-soluble benzodiazepine, has been used in pediatric dentistry or dentistry for the handicapped because of rapid onset. Midazolam can be administered through oral, rectal, intramuscular,intravenous, and intranasal (IN) routes. IN route of midazolam may be considered as effective way to allay for uncooperative autism patients before general anesthesia. In this case report, two autism patients required dental treatment. Intranasal spray of midazolam before general anesthesia was safe and effective procedure of behavioral management.

A modified method for corner mouth lift in scarprone patients

  • Min, Kyung Hee;Lee, Hyun Jic;Jeong, Chang Ho;Jeong, Tae Kwang
    • Archives of Plastic Surgery
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    • v.47 no.6
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    • pp.622-625
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    • 2020
  • Corner mouth lift is in increasing demand among young patients in East Asia. Although various surgical methods exist for corner mouth lift, many patients are reluctant to undergo surgery due to fears of postsurgical scarring. We present a new technique aimed at reducing postoperative scarring. The technique involves triangular excision of the corner of the mouth and incision of the commissure with transposition of a lateral vermilion flap to lift the corner of the mouth. The muscle around the corner of the mouth is dissected to release tension. The corner mouth lift was successfully performed in all patients. It can be effectively used even in patients, such as young Asian women, who are susceptible to hypertrophic scars.

Treatment of 43 Patients with Buerger's Disease (Buerger환자 43명의 치료 경험)

  • Cheun, Jae-Kyu;Jang, Young-Ho;Chung, Jung-Kil
    • The Korean Journal of Pain
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    • v.9 no.1
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    • pp.114-119
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    • 1996
  • Buerger's disease is a nonatherosclerogic occlusive inflammatory disease of medium and small arteries, and veins, of unknown cause. It occurs predominantly in young males who are habitual tabacco users. These patients often complain of painful ulcerations of their digits. The care of this disease is very difficult when the treatment is delayed. Consequently, early treatments are most important to patients with Buerger's disease. This disease can be treated with sympathetic block such as stellate ganglion block for upper extremities and lumbar epidural block, and lumbar sympathetic block for lower extremities. Intravascular regional sympathetic block can be another method of treatment. However, discontinuation of smoking is the most basic and essential treatment for Buerger's disease. We treated 43 Buerger's disease patients with stellate ganglion block and laser therapy. The treatment was not effective for three patients who definitely required amputation.

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Isolation of Dermatophytes from Domestic Animals and Bed Room Dust of Tinea Patients (백선 환자가 사육하고 있는 애완동물 및 침실먼지에서 피부사상균의 분리)

  • Bang, Young-Jun;Kim, Ssang-Young
    • Korean Journal of Clinical Laboratory Science
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    • v.38 no.2
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    • pp.94-98
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    • 2006
  • The mattresses and dust in the bed rooms of nine dermatophytes infected patients and nine domestic animals were examined by the KOH method. Microsporum canis species and Trichophyton mentagrophytes were isolated from cats and rabbits, respectively. The sources of infection of three patients were the M. canis infected cats raised by them and the four other patient's sources of infection were not confirmed. The sites of infection of the nine patients were their heads and those of the domestic animals were their heads and bodies. M. canis species were isolated from the infection sites of three cats and specimens collected by hair brush from the nine domestic animals. T. mentagrophytes species were also isolated from the infection sites of two rabbits. The seven patients had mattresses and bed room dust contaminated with M. canis.

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