• Journal of Nutrition and Health
• /
• v.36 no.5
• /
• pp.491-499
• /
• 2003

Selenium is a strong antioxidant trace mineral, scavenging free radicals. The prevalence of chronic degenerative diseases is increasing in Korean adults with increasing age. The increased cell damage from free radicals has been implicated in the etiology of these diseases, and evidence is accumulating that the low selenium status that comes with advanced aged is involved in the prevalence of age-associated diseases. However, little is known about the selenium status of Koreans, its age-related change and its relationship to dietary nutrient intake. In this study, the serum selenium levels of healthy adult females according to life cycle and its association with blood albumin levels and nutrient intake were examined. Serum selenium level was measured with the Huwo research reactor using the neutron activation analysis method (NAA). The overall proportion of women with selenium deficiency, serum selenium concentrations below 7.0 $\mu\textrm{g}$/dl, was 9.4%. The average serum selenium levels were 12.39 $\mu\textrm{g}$/dl, 9.45 $\mu\textrm{g}$/dl and 9.16 $\mu\textrm{g}$/dl in the young adult, middle-aged and elderly groups, respectively, showing a reduction of selenium status with advancing age. Selenium deficiency was seen only in the elderly group. Generally, serum selenium levels positively or negatively correlated with nutrient intake, but these association patterns differed depending on the age. The nutrients that showed positive correlations with selenium levels were proteins and phosphate in the young adult group (p < 0.05, p < 0.05), and total calcium, potassium and vegetable-origin calcium in the middle-aged group. Vitamin C and fiber were the negative correlated nutrients with serum selenium levels in the elderly group (p < 0.05, p < 0.05). Multiple stepwise regression analysis of the determining factors responsible for selenium status showed that age and serum albumin levels were important factors which explained up to 26.9% variances in serum selenium levels. The average selenium concentrations of Korean adult female subjects were above the deficiency levels in all three age groups. There was a tendency toward decreasing selenium levels as the age of the subjects increased. The factors with the strongest in-fluence on selenium status in healthy adult Korean females were age and serum protein status. (Korean J Nutrition 36(5): 491~499, 2003)

• Korean Journal of Adult Nursing
• /
• v.24 no.1
• /
• pp.85-97
• /
• 2012

Purpose: The aims of this study were to examine the trend of quantitative study in Korean Journal of Adult Nursing published between 1989-2011 and to provide future directions for nursing research in adult health nursing. Methods: A total of 883 published articles were reviewed, and main subject and the methodology were analyzed using descriptive statistics. Results: The most frequently cited keywords were elderly, quality of life, depression, knowledge, stress and anxiety. The survey study was the most popular research design (67.6%) followed by experimental (26.5%), and methodological study (5.5%) design. Over 80% of studies with translated or developed instruments reported reliability for psychometric analysis, while only 18% of the studies reported validity of the instruments they used. In the periods of 2006~2011, significantly more studies utilized experimental design, obtained IRB approval and written consent, and included power analysis for sample size calculation. In recent experimental study, educational program and complimentary therapy were the two most frequently used interventions. Conclusion: Through the analysis of nursing studies published in Korean Journal of Adult Nursing, we found the number of experimental studies has increased and methodological rigor has improved in recent years.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
• /
• v.34 no.4
• /
• pp.275-282
• /
• 2023

Objectives: This study aimed to identify the psychiatric comorbidity status of adult patients diagnosed with attention-deficit hyperactivity disorder (ADHD) and determine the impact of comorbidities on neuropsychological outcomes in ADHD. Methods: The study participants were 124 adult patients with ADHD. Clinical psychiatric assessments were performed by two board-certified psychiatrists in accordance with the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition. All participants were assessed using the Mini-International Neuropsychiatric Interview Plus version 5.0.0 to evaluate comorbidities. After screening, neuropsychological outcomes were assessed using the Comprehensive Attention Test (CAT) and the Korean version of the Wechsler Adult Intelligence Scale, Fourth Edition (K-WAIS-IV). Results: Mood disorders (38.7%) were the most common comorbidity of ADHD, followed by anxiety (18.5%) and substance use disorders (13.7%). The ADHD with comorbidities group showed worse results on the Perceptual Organization Index and Working Memory Index sections of the K-WAIS than the ADHD-alone group (p=0.015 and p=0.024, respectively). In addition, the presence of comorbidities was associated with worse performance on simple visual commission errors in the CAT tests (p=0.024). Conclusion: These findings suggest that psychiatric comorbidities are associated with poor neuropsychological outcomes in adult patients with ADHD, highlighting the need to identify comorbidities in these patients.

• Journal of the Korea Safety Management & Science
• /
• v.8 no.5
• /
• pp.181-191
• /
• 2006

The main objective of this study is to analyze characteristics on the somatotype of modern adult women In order to standardize of products. The sample for this work chosen from data which were collected and measured by Size Korea during two years($2003{\sim}2004$). In order to analyze feature of the somatotype of modern adult women, analysis was peformed in 1,371 subjects(645 twenties women, 725 thirties women) about 21 body parts such as height(4 parts), width(3 parts), thickness(3 parts), circumference(7 parts), length(3 parts) and body weight. According to the result of analysis, it was found that the twenties group was near in slender somatotype, whereas the thirties group was near in fat somatotype compared to standard somatotype.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
• /
• v.29 no.1
• /
• pp.1-4
• /
• 2003

In this study, we showed that neurons could be generated from adult canine bone marrow stem cells by culturing with $DMSO/BHA/FeCl_2$. These neurons differentiated from the bone marrow stem cells formed neurites, expressed neuron-specific markers. This differentiation was enhanced by $FeCl_2$. These results suggest that iron can effectively initiate differentiation of adult bone marrow stem cells into neurons.

• YAKHAK HOEJI
• /
• v.59 no.1
• /
• pp.29-39
• /
• 2015

In recent years, physiologically based pharmacokinetic (PBPK) modeling has been widely used in pharmaceutical industries as well as regulatory health authorities for drug discovery and development. Several application areas of PBPK have been introduced so far including drug-drug interaction prediction, transporter-mediated interaction prediction, and pediatric PK prediction. The purpose of this review is to introduce PBPK and illustrates one of its application areas, particularly pediatric PK prediction by utilizing existing adult PK data and in vitro data. The evaluation of the initial PBPK for adult was done by comparing with experimental PK profiles and the scaling from adult to pediatric was conducted using age-related changes in size such as tissue compartments, and protein binding etc. Sotalol and lorazepam were selected in this review as model drugs for this purpose and were re-evaluated using the PBPK models by GastroPlus$^{(R)}$. The challenges and strategies of PBPK models using adult PK data as well as appropriate in vitro assay data for extrapolating pediatric PK at various ages were also discussed in this paper.

• Journal of the Ergonomics Society of Korea
• /
• v.14 no.2
• /
• pp.51-61
• /
• 1995

The purpose of the study was to provide good fitting of ready-to-wear pants for adult women. To pursue this purpose, the anthropometric data of Korean in 1992 (ADaM(R) 1.0) were analyze. The subjects were 1,580 women aged from 18 to 50 years. The body measurements of six age groups were compared. The results of data analysis showed that the height measurements( waist height, trochanter height, glutial height, perinneum height) of the late 40's were about 3cm shorter than those of the early 20's. The waist circumference of old subject group was 14.1cm larger than those of the young subject group. With rapid growing of waist circumference, the difference of hip and waist circumference was getting smaller with aging. The average difference between hip and waist circumferences of young adult group (18 to 24 yrs) was 24.3cm (SD 3.6cm) and the meaurement of old adult group (45 to 50 yrs) was 15.0cm (SD 5.6cm). The size of the women's pants which were manufactured by the top 50 manufacturers in Korea were compared. The difference between hip circumference and waist circumference listed on the size tag ranged from 12cm to 32cm. The body measurements of subjects and the standard size categories for pants were compared. The results showed that larger size categorise needed to be added to give better fits for older adult group.

• The Korean Journal of Community Living Science
• /
• v.25 no.4
• /
• pp.495-510
• /
• 2014

This study examines the relationship between social support with adult children and neighbors on the life satisfaction of elderly individuals in rural areas. The analysis employed a sample of 764 elderly individuals residing in rural area. Data were analyzed through descriptive statistics, a chi-square test, a t-test, and a multiple regression analysis. First, the respondents reported moderate life satisfaction. Those respondents living alone were less likely to report life satisfaction than those with a spouse. Second, the respondents were more likely to be in contact with their neighbors than their adult children. Third, the respondents were more likely to receive social support from adult children than provide it to them. By contrast, the respondents were more likely to provide social support to neighbors than receive it from them. Fourth, economic status and contact with adult children and neighbors had signigicant effects on the life satisfaction of the respondents. Gender, religion, economic status, health status, increased contact with adult children, and instrumental support to neighbors had positive effects on the life satisfaction of elderly two-person household.

• Journal of Fashion Business
• /
• v.10 no.1
• /
• pp.132-147
• /
• 2006

The purpose of this study is to provide for the basic data useful to the effective production and marketing of the foundation garment befitting adult women's shapes and preferences, and thereby, help them improve their apparel life. For this purpose, 563 Korean women aged between 20-59 were sampled to survey their recognition and actual wearing condition of foundation garments and positively identify the factors affecting the practices and thereupon, determine the correlations among them by age group. The raw data of this study is processed by SPSS Win(10.1) and analyzed by using frequency, percentage, $x^2$-test, ANOVA, Duncan-test. The most of adult women were aware of their foundation size and the absolute majority of them wore brassieres, while a half of them used the girdles. The adult women had 5.7 Brassieres and 2.2 Girdles. The use of the foundation depended much on user's age or seasons. They had begun to wear Brassieres at their age of 15 on an average and Girdle around their age of 19 depending their individual needs. It has been found through this study that adult women's is actual wearing condition of foundation garments differ by age group, which may well suggest that foundation production need to consideration this age-wise practices when setting up their foundation production and marketing strategies.

• Childhood Kidney Diseases
• /
• v.22 no.1
• /
• pp.7-11
• /
• 2018

Significant advances in the diagnosis and medical care of children with chronic kidney disease (CKD) are major reasons for the better survival rates of children and adolescents with CKD than the survival rates reported in previous decades. These patients are reaching adulthood, and therefore require a transition to adult medical care. This transition phase is well-recognized to be associated with considerably increased morbidities and medical problems, such as non-adherence, graft loss after transplantation, and loss to follow-up. Low adherence increases morbidity and medical complications and contributes to poorer qualities of life and an overuse of the health care system. However, these tragic outcomes may be avoidable through a structured and well-defined transition program. In the last decade, there has been increasing interest to resolve these medical and psychological problems that occur during the transfer of young adult patients from pediatric to adult renal units. The aims of a successful transition from pediatric to adult medical care include enhancing the individual development of better health-competence and stabilizing, or even improving, the state of health. This review will focus on various aspects of the transition phase of adolescents who have CKD or who underwent kidney transplantation from pediatric to adult nephrology care.