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DIFFERENTIATION OF ADULT CANINE BONE MARROW STEM CELLS INTO NEURONS  

Choi, Byung-Ho (Department of Oral & Maxillofacial Surgery, College of Dentistry, Yonsei University)
Huh, Jin-Young (Department of Dentistry, Kangnung Asan Hospital)
Park, Dong-Joon (Department of Otolaryngology, Wonju College of Medicine, Yonsei University)
Kim, Byoung-Yong (Me-Plus dental clinic)
Lee, Seoung-Ho Robert (Korean Baylor Academy and KIDA)
Park, Sun-Young (Department of Oral & Maxillofacial Surgery, College of Dentistry, Yonsei University)
Publication Information
Journal of the Korean Association of Oral and Maxillofacial Surgeons / v.29, no.1, 2003 , pp. 1-4 More about this Journal
Abstract
In this study, we showed that neurons could be generated from adult canine bone marrow stem cells by culturing with $DMSO/BHA/FeCl_2$. These neurons differentiated from the bone marrow stem cells formed neurites, expressed neuron-specific markers. This differentiation was enhanced by $FeCl_2$. These results suggest that iron can effectively initiate differentiation of adult bone marrow stem cells into neurons.
Keywords
Neuronal differentiation; Tissue engineering; Cell culture; Stem cells;
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