• 동아시아식생활학회지
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• 제1권1호
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• pp.17-29
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• 1991

The Hong's-Zu-Bang-Moon, although it is not know when and by whom it was written, is estimated to have written in the middle of 1800, but has not been published yet. In general, other cooking books in Yi's Dynasty were on the cooking methods of a variety of foods. But the book deals solely with brewing, which is the trait of it. The book comprises a total of 36 items, among which So-Gog-Ju wine was excluded because only a part of it was recorded. Another item deleted, written vaguely and difficult to understand was, on a closer analysis of its content, 'Song-Soon-Ju wine'. According to the analysis of this book, the cereals used for brewing were 59 percent of regular rice and 41 percent of sticky rice including other 12 kinds of special materials. As for the processes, the precesses using Jee-Ae-Bop was dominant. The processing technique whose special words and expressions were analyzed in this study, were divided into 18 preparation methods, 45 processing ones, and 7 heating ones. The temperature processing whose expressions were analyzed here were divided into 6 cooking processes, 7 medium ones and 3 heating ones. The measurement unit of 'Doe' was most often used. It tried to show relatively accurate measurements but showed just approximate ones. There were 19 kinds of brewing utensis. Urns were most often used, but it was impossible to discern and kind. As for the tast of the wines, the writer showed his subjective expressions. The margianal point in this study is that it was very difficult to interpret the book. The closing up of twings of on azaled over the urn had no scientific base but said something of korean folkways at that times.

• 한국의사학회지
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• 제14권2호
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• pp.109-152
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• 2001

Throughout this paper, I adjusted the study of 'Qian Yi'(錢乙)'s Medical Thought, and the following is the summary. 1. 'Qian Yi' wrote 'Xiao Er Yao Zheng Zhi Jue'("小兒藥證直訣", edited by 誾季忠), and there were 'Shang Han Lun Zhi Wei'("傷寒論指微"), 'Ying Ru Lun', however those are loss of the record. 2. Qian Yi's 'Zhi Jue'("直訣") was influenced by 'Lu Xin Jing', yet if we compare the quality of 'Sheng Li, Byeng Li, Bang Jae'(生理, 病理, 方劑), 'Lu Xin Jing' cannot be the foundation of 'Zhi Jue'. He took over 'Nei Jing, Shang Han Lun, Jin Gui Yao Lue, Shen Long Ben Cao Jing, Tai Ping Sheng Hui Fang'("內經", "傷寒論", "金?要略", "神膿本草經", "太平聖惠方") and put them together to the direct clinical experiences of pediatrics. 3. There is no reference regarding the difficulties of pediatric diagnosis and diseases in 'Huang Di Nei Jing'("黃帝內經") Before 'Bei Song'(北宋), regardless of the lack of data related to pediatric diseases, 'Qian Yi' established the pediatric system in 'Xiao Er Yao Zheng Zhi Jue' for the first time. 4. In his diagnosis of the pediatric diseases, he 'Si Zhen He Can'(四診合參), also considered in the eye exam seriously. In addition, he closely combined 'Wu Zang Bian Zheng'(五臟辨證), and diagnosis the pediatric diseases. 5. 'Wu Zang Bian Zheng', what Qian established method was based on 'Zheng Ti Guan'(整體觀) in 'Huang Di Nei Jing'. It was based on clinical experiences and established the perspectives of 'Tian Ren Xiang Ying'(天人相應). First of all, he pinpointed 'Zhu Zheng'(主證) clearly. Secondly, he pinpointed the relationships to symptoms and then, he distinguished a generic character of 'Xu, Shi, Han, Re'(虛, 實, 寒, 熱). Finally, he made an induction from genealogical pediatric physiology. 6. 'Qian Yi' took a serious view of 'Ban Zhen'(斑疹), the inadequate field in those days. At that time, he criticized on the habituation of the misuse of medication. He treated separately which 'Ji Jing'(急驚) as 'Liang Xie'(凉瀉) and 'Man Jing'(慢驚) as 'Wen Bu'(溫補). He proposed 'Cong Gan Zhu Feng, Xin Zhu Jing'(從肝主風, 心主驚) theory and formulated 'Jing Feng'(驚風) theory as well. 7. As an opponent of a tendency to misusage of medicine, 'Qian Yi' made out a prescription with pliant medicine. He emphasized on the treatment to 'Gong Bu Shang Zheng, Bu Bu Zhi Xie, Xiao Bu Jian Shi'(攻不傷正, 補不滯邪, 消補兼施) because he had so lucid demonstration to 'Xu Shi Han Re'(虛實寒熱) of the five viscera in the field of 'Bang Yak'(方藥). 8. There were no pediatrics schools at that time, however, the pediatrics was being made up gradually by 'Jin Yuan Si Da Jia'(金元四大家) who was influenced by 'Qian Yi'. He raised an objection to medical treatment using pliant medicine. 'Qian Yi' applied 'Qu Xia'(驅下) treatment using 'Han Liang'(寒凉) medicine. 'Han Liang Pai'(寒凉派) is greatly influenced by Qian. 'Chen Wen Zhong'(陳文中) had a great impact on 'Han Liang Pai' who used a 'Zao Shu Wen Bu'(燥熟溫補) medicine for treatment. Since 'Song Jin'(宋金), he had a tremendous influence on pediatrics treating patients in both 'Han Wen'(寒溫) ways. 9. 'Qian Yi' had an influence on his medical thoughts on future generations, especially to 'Wan Quan'(萬全) of 'Ming Dai', 'Wu Tang'(吳塘) of 'Qing Dai'(淸代) and 'Yun Shu Jie'(?樹珏) of 'Min Guo'(民國). 'Wan Quan' is an advocate of 'You Yu, Bu Zu Zhi Shuo'(有餘, 不足之說)of 'Xiao Er Wu Zang'(小兒五臟) that he revealed Qian's 'Wu Zang Bian Zheng'(五臟辨證). 'Wu Tang' disclosed Qian's 'Xiao Er Ti Zhi Shuo'(小兒體質說) and 'Xiao Er Ke'(小兒科)'s 'Yong Yao Lun'(用藥論), therefore, he uncovered pediatric physiological characteristics through the advocate of Qian's 'Zang Fu Rou Ruo, Ji Gu Nen Qie, Yi Xu Yi Shi, Yi Han Yi Re' (臟腑柔弱, 肌骨嫩怯, 易虛易實, 易寒易熱). 'Yun Shu Jie' developed intrinsic relationships among time, symptom and 'Tian Ren Xiang Ying Guan'(天人相應觀), What 'Qian Yi' stated about them. And also, he developed Qian's 'Di Huang Wan'(地黃丸), 'Xie Qing Wan'(瀉靑丸), 'Yi Huang San'(益黃散) clinical usages as well. 10. Regarding Qian's 'Wu Zang Xu Shi'(五臟虛實), it has an influence on 'Zhang Yuan Su'(張元素)'s 'Zang Fu Bing Ji Bian Zheng'(臟腑病機辨證). 'Di Huang Wan', 'Xie Qing Wan', 'Xie Xin Tang'(瀉心湯), 'Yi Huang San', 'Xie Huang San'(瀉黃散) are the standard prescription of 'Wu Zang Bu Xie'(五臟補瀉). It is under the influence of Qian's treatment. Besides, 'Qian Yi' took a serious view of 'Xiao Er'(小兒)'s 'Pi Wei'(脾胃). 'Qian Yi' had an impact on 'Li Dong Yuan'(李東垣) one of the member of 'Bu Tu Pai'(補土派). 'Di Huang Wan', which placed great importance on 'Bu Yi Shen Yin'(補益腎陰), had a great impact on 'Da Bu Yin Wan'(大補陰丸) and 'Jin Yuan Si Da Jia' as well. 11. In a theory of Qian's 'Wu Zang Bian Zheng', though it had been stated clearly in 'Wu Zang Bian Zheng', but he neglected in 'Liu Fu Bian Zheng'(六腑辨證). In prescription field, The problem with the medicine is that it is either toxic or mineral, therefore, we are not able to use those medicine in a clinical testing at the present time.

• 대한의료기공학회지
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• 제2권2호
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• pp.185-199
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• 1998

Going back to long chinese medical history, there were many different methods of treatment according to the origin of local chinese areas, such as Bian-Shi(?石) from east, herbal therapy from west, acupuncturing from south, moxibustion from north, and mainpulating therapy from middle china. In the midst of these therapies, acupuncture needling had developed very much both in theories, shapes, usages and also in theraputic boundray. Historical books dealing with acupuncture had introduced and used Jiu-Zhen as a tool for acupuncture needling in common. But there are some differences between each texts about in shape, use, and there are also another different point of view about the interrelationship between Bian-Shi and Ji-Zhen. So the author, in this research, tried to look for how Jiu-Zhen had took on its real kinds, adaptive usages, theraputic boundaries, many different skills of needing. By researching over ${\ulcorner}$ Ling-Shu, Jiu-Zhen(靈樞,九鍼)${\lrcorner}$, ${\ulcorner}$ Ling-Shu, Jiu-Zhen-Shi- Yi-Yuan(靈樞,九鍼十二原)${\lrcorner}$, ${\ulcorner}$ Ling-Shu, Guan-Zhen(靈樞,官鍼)${\lrcorner}$, and by compar- ing them with the contents of Jiu-Zhen in ${\ulcorner}$ Zhen-Jiu-Yi-Jing(鍼灸甲乙經)${\lrcorner}$ ${\ulcorner}$Zhen-Jiu-Da-Cheng (鍼灸大成)${\lrcorner}$, the author discovered small conclusions such as following. 1. Taking Jiu-Zhen in a narrow sense, it only repesents nine different needle used in different cases. But in large sense, this means nine different deedling methods using each different needles which is represented in the form of Wu-Ci ( 五剌 ), Shi-Yi-Ci ( 十二剌 ) in ${\ulcorner}$ Ling-Shu, Guan-Zhen ${\lrcorner}$ 2. Jin-Zhen has been first originated from stone age as a substitute for Bian-Shi and through bronze and iron age, it followed a process of it's own shape and applicating functions. As an example, the moxibustional therapies shown in ${\ulcorner}$ Zu-Bi-Shi-Yi-Mai- Jiu-Jing ( 足臂十一脈灸經 )${\lrcorner}$ ${\ulcorner}$ Yin-Yang-Shi-Yi-Mai-Jiu-Jing ( 陰陽十一脈灸經)${\lrcorner}$ in ahead of ${\ulcorner}$ Nei-Jing ( 內經 )${\lrcorner}$ era, was relationship in acupuncturing skills and shape. So Jiu-Zhen had been originated on the base of Bian-Shi in ancient times to develop into delicate shape, skill, and theraputic foundation of modern oriental medicine.

• 한국항해항만학회:학술대회논문집
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• 한국항해항만학회 2001년도 Proceeding of KIN-CIN Joint Symposium 2001 on Satellite Navigation/AIS, lntelligence , Computer Based Marine Simulation System and VDR
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• pp.177-186
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• 2001

Based upon the previous experiences and typical oases of typhoon evasion fur ships as well as tile achievement in scientific research in this detrain, we developed the Intelligent Typhoon Evasion System for Ships. It consists of five subsystems, including electronic charts, ship movement management, typhoon information query and automatic plotting, real-time calculation of ship-typhoon situation, intelligent typhoon evasion decision making. With the synthetical application of analogy theory, synoptic chart, satellite cloud picture analysis, typhoon digital forecast and other relevant technologies, we leave established the typhoon evasion data bases. model bases and knowledge bases, which make it possible to automatically track the ships and typhoon paths. The system can realize ship-typhoon situation analysis, risk levee assessment, typhoon paths correction and course synoptic forecast, and intelligent typhoon evasion decision making.

• 한국독어학회지:독어학
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• 제8집
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• pp.123-142
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• 2003

Diese Arbeit hat sich zur Aufgabe gestellt, eine Bedeutungsstruktur der deutschen faktitiven Verben mit der koreanischen faktitiven Verben zu vergleichen. Da vergleichende Untersuchung der faktitiven Verben im Deutschen und Koreanischen einem Vergleich einer sprachlicher Seite von beiden Sprachen entspicht, ist die Aufgabe dieser Arbeit eine Aufstellung des Unterschiedes der Bedeutungsstruktur im Bereich der Worbildungen der faktitiven Verben. Als Worbildungsmittel der deutschen faktitiven Verben gibt es $\~(e)n,{\;}ab{\~},{\;}an{\~},{\;}auf{\~},{\;} aus{\~},{\;}be{\~},{\;}durch{\~},{\;}ein{\~},{\;}ent{\~},{\;}er{\~},{\;}{\~}igen,{\;}{\~}ieren,{\;}uber{\~},{\;}ver{\~}und zer{\~}$, Als Worbildungsmittedl der koreanischen faktitiven Verben gibt es ${\~}i{\~},{\;}{\~}hi{\~},{\;}{\~}ri{\~},{\;} {\~}gi{\~},{\;}{\~}u{\~},{\;}{\~}gu{\~},{\;}{\~}chu{\~},{\;}{\~}ge{\;}ha{\~}und{\;}{\~}siki{\~}$. Deutsche faktitive Verben lassen sich folgende gliedrn : 1. Faktitive Verben, die im Bereich der $\"{a}u{\ss}erlichen$ Handlungen Zustand oder Eigenschaft direkt bewirken. 2. Faktitive Verben, die im Bereich der innerlich-geistigen Handlungen indirekt bewirken. 3. Faktitive Verben, die $Gegenst\"{a}nde$ versinnbildlichen. Koreanisch faktitive Verben lassen sich folgende gliedern : 1. Verben, bei denen Objekte Subjekte der defensiven Handlungen nach den faktitiven Handlungen werden, 2. Verben, die den Zustand der Sachen nach den faktitiven Handlungen $ver\"{a}ndern$. 3. Verben, die Eigenschaft der Sache nach den faktitiven Handlungen $ver\"{a}ndern$

• Asian Pacific Journal of Cancer Prevention
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• 제13권9호
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• pp.4295-4300
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• 2012

Objective: To investigate the therapeutic potential of human embryonic stem cells (hESCs) as a vaccine to induce an immune response and provide antitumor protection in a rat model. Methods: Cross-reactivity of antigens between hESCs and tumour cells was screened by immunohistochemistry. Fischer 344 rats were divided into 7 groups, with 6 rats in each, immunized with: Group 1, hESC; Group 2, pre-inactivated mitotic NuTu-19; Group 3 PBS; Group 4, hESC; Group 5, pre-inactivated mitotic NuTu-19; Group 6, PBS; Group 7, hESC only. At 1 (Groups 1-3) or 4 weeks (Groups 4-6) after the last vaccination, each rat was challenged intraperitoneally with NuTu-19. Tumor growth and animal survival were closely monitored. Rats immunized with H9 and NuTu-19 were tested by Western blot analysis of rat orbital venous blood for cytokines produced by Th1 and Th2 cells. Results: hESCs presented tumour antigens, markers, and genes related to tumour growth, metastasis, and signal pathway interactions. The vaccine administered to rats in Group 1 led to significant antitumor responses and enhanced tumor rejection in rats with intraperitoneal inoculation of NuTu-19 cells compared to control groups. In contrast, rats in Group 4 did not display any elevation of antitumour responses. Western blot analysis found cross-reactivity among antibodies generated between H9 and NuTu-19. However, the cytokines did not show significant differences, and no side effects were detected. Conclusion: hESC-based vaccination is a promising modality for immunotherapy of ovarian cancer.

• Asian Pacific Journal of Cancer Prevention
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• 제16권8호
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• pp.3233-3239
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• 2015

Background: Whether depression causes increased risk of the development of breast cancer has long been debated. We conducted an updated meta-analysis of cohort studies to assess the association between depression and risk of breast cancer. Materials and Methods: Relevant literature was searched from Medline, Embase, Web of Science (up to April 2014) as well as manual searches of reference lists of selected publications. Cohort studies on the association between depression and breast cancer were included. Data abstraction and quality assessment were conducted independently by two authors. Random-effect model was used to compute the pooled risk estimate. Visual inspection of a funnel plot, Begg rank correlation test and Egger linear regression test were used to evaluate the publication bias. Results: We identified eleven cohort studies (182,241 participants, 2,353 cases) with a follow-up duration ranging from 5 to 38 years. The pooled adjusted RR was 1.13(95% CI: 0.94 to 1.36; $I^2=67.2%$, p=0.001). The association between the risk of breast cancer and depression was consistent across subgroups. Visual inspection of funnel plot and Begg's and Egger's tests indicated no evidence of publication bias. Regarding limitations, a one-time assessment of depression with no measure of duration weakens the test of hypothesis. In addition, 8 different scales were used for the measurement of depression, potentially adding to the multiple conceptual problems concerned with the definition of depression. Conclusions: Available epidemiological evidence is insufficient to support a positive association between depression and breast cancer.

• Journal of Acupuncture Research
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• 제22권1호
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• pp.29-39
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• 2005

십이경근(十二經筋)의 침구학적(鍼灸學的) 응용(應用)을 위하여 경사(經篩)의 형성과정(形成過程)과 그 본래의 의미에 대한 이해가 필요 할 것으로 사료되어 <<경근(經筋)>>에 기재된 십이경근(十二經筋)에 대한 분석(分析)을 통하여 다음과 같은 결론을 얻었다. 1. <<내경(內經)>>에 수록된 "근"(筋)의 의미는 근육(筋肉), 건,(腱) 표재정맥(表在靜脈), 신경(神經) 등의 개염(槪念)을 포괄하고 있으며, <<경근(經筋)>>에서는 근육(筋肉)과 건을(腱) 의미를 내포하고 있다. 2. 경근(經筋)의 순행노선(循行路線)은 사지말단(四肢末端)에서 두신(頭身)으로 향하는 향심주(向心注) 노선(路線)을 보이고 있으며, 경근(經筋)의 병후(病候)는 대부분 순행부위에 따른 전근(轉筋)이나 동통(疼痛)으로 이러한 병후(病候)는 <<족비(足臂)>>의 경맥병후(經脈病候)의 특징과 같은 것으로 "소생병(所生病)"의미를 내포하고 있다. 3. 십이경근(十二經筋)은 해부학적(解剖學的) 관찰에 의해 형성된 것이 아니라 십이경맥(十二經脈)의 순행노선(循行路線)을 참조로 전신의 근육(筋肉)을 십이구역(十二區域)으로 분류(分類)하여 형성된 것으로 "근"(筋)을 통하여 인체(人體)를 상하로 연계시키는 규율에 대해 또 다른 가설을 제시한 것으로 사료된다.

• Applied Biological Chemistry
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• 제41권6호
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• pp.465-470
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• 1998

미생물이 생산하는 유기폐수처리용 생물응집제를 개발하기 위하여 보관균주 및 자연계로부터 100 units/ml 이상의 응집활성을 나타내는 응집제 생산균주를 1차로 분리하고 돈분폐수에서 가장 높은 제거율을 보인 KH-54를 최종 선별하였다. 선별된 균주는 Aeromonas hydrophila로 동정되었으며 응집제 생산을 위한 최적 배양조건은 2.0% mannitol, 0.05% ammonium chloride, 0.02% $KH_2PO_4$, 0.01% $MgSO_4{\cdot}7H_2O$, 0.05% yeast extract 조성의 배지와 초기 pH 7.0, 배양온도 $25^{\circ}C$ 및 교반속도 150 rpm 의 환경인자들이었다. 상기의 조건으로 4일 배양하였을 때 770 units/ml의 응집활성과 81%의 높은 nephelometer turbidity unit(NTU) 제거율을 나타내었으며 이 응집물질은 돈분폐수 이외 두부공업폐수 92%, 제당폐수 78%, 주정공업폐수 68% 및 항생물질 발효공업폐수 36%의 NTU 제거율을 각각 나타내었다.

• 철학연구
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• 제116권
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• pp.281-312
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• 2010

이 글은 '언어적 패러다임 전환'을 겪은 이후 오늘날의 철학적 문제 상황에서 시도되는 모든 탈선험화의 과정이 이미 '냉소적' 단초에 도달함으로써 상대주의 특수주의 회의주의가 강화되고, 그 결과 이성과 진리의 이념에 대한 비판, 거부 그리고 무관심이 확산되고 있는 시대적 징후를 문제삼는다. 때문에 필자는 역설적으로 바로 이 지점에서 '도덕적 이성의 현실성' 회복의 긴급성과 절박성을 생각한다. 따라서 이 글의 목적은 도덕적 이성의 현실성 회복과 관련해서 실제로 어떤 이론적 인식 및 도덕적 인식이 참된 것, 즉 '객관적으로 타당한 것'으로 '증명'된 논증이 존재한다는 것을 보여 주는 것이다. 필자는 이를 위해서 먼저 철학적으로 상대주의적 회의주의적 단초들의 문제를 짚고(2), 이 단초의 극복을 위한 합리적 도덕적인 근거의 정당화 작업을 시도할 것이다(3). 이어서 이 정당화 작업이 궁극적으로는 현대의 최종근거지음의 문제와 밀접한 연관을 맺고 있음을 살펴보고(4), 이것은 결국 오류주의테제와의 대결을 통해서 인식이론적인 객관적 타당성을 획득하게 됨을 짚은 뒤에(5) 이 글을 마무리할 것이다(6).