• Herbal Formula Science
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• v.29 no.4
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• pp.331-331
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• 2021

• Proceedings of the Korean Environmental Sciences Society Conference
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• 2020.10a
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• pp.94-94
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• 2020

• Toxicological Research
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• v.29 no.3
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• pp.173-179
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• 2013

In-utero exposure to valproic acid (VPA) has been known as a potent inducer of autism spectrum disorder (ASD), not only in humans, but also in animals. In addition to the defects in communication and social interaction as well as repetitive behaviors, ASD patients usually suffer from gastrointestinal (GI) problems. However, the exact mechanism underlying these disorders is not known. In this study, we examined the gross GI tract structure and GI motility in a VPA animal model of ASD. On embryonic day 12 (E12), 4 pregnant Sprague-Dawley (SD) rats were subcutaneously injected with VPA (400 mg/kg) in the treatment group, and with phosphate buffered saline (PBS) in the control group; the resulting male offspring were analyzed at 4 weeks of age. VPA exposure decreased the thickness of tunica mucosa and tunica muscularis in the stomach and ileum. Other regions such as duodenum, jejunum, and colon did not show a significant difference. In high-resolution microscopic observation, atrophy of the parietal and chief cells in the stomach and absorptive cells in the ileum was observed. In addition, decreased staining of the epithelial cells was observed in the hematoxylin and eosin (H&E)-stained ileum section. Furthermore, decreased motility in GI tract was also observed in rat offspring prenatally exposed to VPA. However, the mechanism underlying GI tract defects in VPA animal model as well as the association between abnormal GI structure and function with ASD is yet to be clearly understood. Nevertheless, the results from the present study suggest that this VPA ASD model undergoes abnormal changes in the GI structure and function, which in turn could provide beneficial clues pertaining to the pathophysiological relevance of GI complications and ASD phenotypes.

• Journal of Physiology & Pathology in Korean Medicine
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• v.16 no.3
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• pp.424-434
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• 2002

In Jang-Sang theory, ‘Sang’ indicates ‘Hyung Sang’. The internal organs appear it's shapes(Hyung Sang) outward. ‘Hyung Sang’ is concept that was used on 「the book of changes」(周易) and 「Nei Ching」(內經) to means a thing's shapes and conditions. ‘Hyung’ is the shape, an organization composing a thing and ‘Sang’ is the symptom, an essence(a seed) immanenting a thing. To observe Hyung Sang, it have to apply the principle that ‘the sky and man correspond each other(天人相應)’. Usually ‘Hyung’ appears as shapes and ‘Sang’ appears as colors and conditions. Diagnosis on the basis of Hyung Sang put first the external expression of the five Jang six Bu organs and Jung-Ki-Shin-Hyul(精氣神血). So a doctor has to unite shapes, colors, pulse and symptoms(形, 色, 脈, 症) when diagnosis a patient. The theory of Hyung Sang includes the basic theories of the oriental medicine, the theory for Yin-Yang and the five element(陰陽五行論), organ picture(Jang-Sang), meridians(經絡學說), the five circuit phases and the six atmospheric influences(運氣學說), physical constitution(體質學說). I think that treatment based on Hyung Sang is shown the essence of the oriental medicine well. In the future, I think, we need to study more about the theory of Hyung Sang.

• Journal of Physiology & Pathology in Korean Medicine
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• v.17 no.2
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• pp.275-292
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• 2003

In terms of Yin and Yang theory, Dam represents excessive Yang and deficient Yin, and Bangkwang means excessive Yin and deficient Yang. In terms of Ki and Hyung, Dam is vigorous Ki and flabby Hyung, and Bangwang is strong Hyung and weak Ki. In terms of the balance of Ki and Blood, Dam is more Ki and less Blood and Bangkwang is the opposite. In terms of meridians concerned, Dam belongs to Joksoyangdam meridian(足少陽膽經) and Bangkwang belongs to Joktayangbangwang meridian(足太膀胱經), Mr. Jeesan saw that the person having vigorous Ki and flabby Hyung tends to be dynamic and the person having strong Hyung and weak Ki tends to be static and designated both as Dam and Bangkwang, respectively, Meridians are the route of Ki and Blood in the body and since their titles are thought to imply basic oriental medical theories, they are better choices to be comprehensive and systematic than other terms. In the 12 meridians, the 6 foot meridians are more important than the other hand meridians because human beings adapt themselves to the earth. Among the 6 foot meridians, the 3 Yang foot meridians are more representative of the body since they cover more of the body. Joksoyangdam meridian(足少陽膽經) is related to more Ki and less Blood and thus is a relevant term to describe Dam. Likewise Joktaeyangbangkwang meridian(足太膀胱經) is related to more Blood and less Ki and thus can correspond to the term 'Bangkwang'. In addition, the Dam organ and Dam meridians meet the condition of excessive Yang and deficient Yin, vigorous Ki and flabby Hyung, more Ki and less Blood, on the other hand, the BangKwang organ and Bangkwang meridians meet the condition of excessive Yin and deficient Yang, strong Hyung and weak Ki, more Blood and less Ki. Thus the terms of Dam and Bangkwang satisfy the basic concepts Mr. Jeesan established.

• Journal of the Korean Society of Industry Convergence
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• v.21 no.1
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• pp.17-27
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• 2018

We propose a new approach to control a biped robot motion based on iterative learning of voice command for the implementation of smart factory. The real-time processing of speech signal is very important for high-speed and precise automatic voice recognition technology. Recently, voice recognition is being used for intelligent robot control, artificial life, wireless communication and IoT application. In order to extract valuable information from the speech signal, make decisions on the process, and obtain results, the data needs to be manipulated and analyzed. Basic method used for extracting the features of the voice signal is to find the Mel frequency cepstral coefficients. Mel-frequency cepstral coefficients are the coefficients that collectively represent the short-term power spectrum of a sound, based on a linear cosine transform of a log power spectrum on a nonlinear mel scale of frequency. The reliability of voice command to control of the biped robot's motion is illustrated by computer simulation and experiment for biped walking robot with 24 joint.

• The Journal of Internal Korean Medicine
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• v.24 no.4_2
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• pp.1007-1013
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• 2003

Ramsay Hunt Syndrome is caused by infection of herpes zoster and associated with otalgia, herpetic eruptions, facial palsy, trigerminal pain and cochleovestibular dysfunction such as deafness, tinnitus, vertigo and so on. A 60-year old female, who has tinnitus, peripheral facial palsy, deafness, vertigo, postauricular pain and herpetic eschar, had been admitted to Wonkwang University Oriental Jeonju Medicine Hospital. We treated this patient with Daehwangchijahwangbaeg-byung and Yongdamsagantang-gami, and the patients showed improvement in the symptoms. So we describe the process and contents about the way the patient was cured.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.24 no.1
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• pp.171-180
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• 2011

Objective : The efficacy of auricular acupuncture for the treatment of allergic rhinitis has been reported. Methods : Twelve rhinitis patients patients were enrolled in this study. Every patient received auricular acupuncture 2 times a week during 4 weeks. Auricular acupuncture points used were M101(肺), M13(副腎), M16(內鼻), M22(內分泌), M33(額), M55(神門). Patients nasal symptoms and QOL were assessed before and after 4 weeks treatment by total nasal symptom score(TNSS), total non nasal symptom score(TNNSS) and Rhinoconjuctivitis quality of life questionnaires(RQLQ). Results : 1. Among items of TNSS, nasal congestion-sneezing were significantly improved. and Total TNSS Scores were significantly improved.(p<0.05) 2. TNNSS were no significant difference. 3. Among items of RQLQ, nasal&eye problem&nasal symptom were significantly improved.

• The Journal of Internal Korean Medicine
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• v.12 no.2
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• pp.129-137
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• 1991

This study has been carried out to investigate the cause symptom and treatment of wind-coughing ( 風嗽 ) by referring to 38 literatures. The results were obtained as follows; 1. The factors causing wind-coughing ( 風嗽 ) is wind-air. The 1st factors are mistaking of transport lung-air ( 肺氣不宣 ) and cleaning lung (肺失淸肅). 2. The symptom of wind-coughing ( 風嗽 ) is as follows. Bi Saek Sung Jung ( 鼻塞聲重 ), Gu Gun Hu Yang ( 口乾喉痒 ), A Mi Kung I Hae ( 語未竟而咳 ), Maek Bu ( 脈浮 ), Jeang Han Jang Yul ( 憎寒壯熱 ), Ja Han OU Pung ( 自汗惡風 ), Bun Jo ( 煩躁 ), Bi Ryu Chung Chae ( 鼻流淸?), Ya Jung 11 Jyung ( 夜重日輕 ). 3. The treatment-method of wind-coughing ( 風嗽 ) is as follow. Bal San Bul Ga Ha ( 發散 不可下 ), So Pung San Han ( 疏風散寒 ), Chung Yul ( 淸熱 ), Sun Pae Ji Hae ( 宣肺止咳 ). 4. The treatment-herbs of wind-coughing ( 風嗽 ) is as follow. Kwan Dong Hwa San ( 款冬花散 ), Gun Bi Cho San ( 金沸草散 ), Sam Yo Tang ( 三拗湯 ), Ji Hae San ( 止嗽散 ), Hang So San ( 杏蘇散), Sang Kuk Yeam ( 桑菊飮).

• 한국HCI학회:학술대회논문집
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• 2008.02b
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• pp.614-623
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• 2008

본 연구는 사용자 만족 중심의 기존 사용자 경험 관련 연구들이 가지고 있는 한계를 보완하기 위하여 감정적 애착이라는 새로운 개념을 도입함으로써 사용자 경험 연구의 새로운 시각을 제공하고자 하는 목적으로 진행되었다. 이를 의하여 [연구 1]에서는 감정적 애착과 관련된 기존 이론들에 대한 조사를 통하여 사용자들의 디지털 기기에 대한 감정적 애착 형성에 영향을 미칠 수 있는 이론적 경험 요소로서 지각된 자아 일치감과 지각된 사회적 고양감이라는 개념들을 도출하였으며, 이를 기반으로 사용자 경험의 관점에서 새로운 이론적 모형을 개발하고, 한국의 핸드폰 사용자들을 대상으로 한 설문을 통하여 개방된 감정적 애착 형성 모형의 타당성을 실증적으로 검증하였다. 또한 [연구 2]에서는 5 개국 (한국, 미국, 독일, 러시아, 인도)에서 4 개의 디지털 기기 (핸드폰, MP3 플레이어, LCD TV, 냉장고) 사용자들을 대상으로 한 Contextual Interview 를 실시하여 실제 디지털 기기의 개발 및 디자인에 구체적인 시사점을 제공할 수 있는 경험 요소들을 추가적으로 도출하였다. 마지막으로 [연구 3]에서는 [연구 2]를 통하여 도출된 구체적인 사용자 경험 요소들을 [연구 1]에서 개방된 이론적 모형에 반영하여 구체화된 감정적 애착 형성 모형을 개방하고, 구체화된 모형의 타당성을 미국 핸드폰 사용자들을 대상으로 한 설문을 통하여 추가적으로 검증하였다.