• 한국수정란이식학회지
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• 제13권2호
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• pp.191-197
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• 1998

Immature nocytes and in VitrO matured Oocytes collected from the slaughtered Korean cattle were frozen slowly with 10% ethylene glycol+5% polyvinyl pyrolidine+0.05M trehalose (l0EPT), 10% ethylene glycol+5% ficoll+0.05M sucrose (1OEFS), or 10% ethylene glycol+5% ficoll+0.05M trehalose (l0EFT) by cell freezer (experiment 1). And also,They were ultra-rapidly frozen with 30% ethylene glycol+10% polyvinyl pyrolidine+0.5M trehalose (3OEPT) or 30% ethylene glycol+18% ficoll+0.5M sucrose (3OEFS) using electron microscope grid (experiment 2). In experiment 1, the cleavage rate was 23.0% when immature oocytes were frozen slowly using various cryoprotectants descrihed above, and 5.1% of cleaved oocytes developed to over morula stage after in Vitro fertilization (IVF). There were no significant differences among these groups. When matured oocytes were frozen slowly, the total cleavage rate was 19.7%, and over morula stage was 3.2%. lOEPT (4.8%) and EFS (4.4%) were slightly more effective than l0EFT (0.0%) for development in vitro. Only in l0EFT treated group, immature oocytes have higher developmental capacity than matured ones, when they were frozen slowly and IVF after thawing. In experiment 2, oocytes were ultra-rapidly frozen using the electron microscope grid with two kind of cryoprotectants described above. In immature oocyte group, the cleavage rate was 13.9% and 5.8% of cleaved oocytes developed to over morula stage after IVF, and in matured group, 25.7 and 7.6%, respectively. There were no significant differences between two kind of cryoprotectants, but in ultra-rapid freezing using electron microscope grid, the efficiency is slightly higher in matured oocyte group.

• 한국콘텐츠학회논문지
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• 제13권3호
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• pp.184-197
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• 2013

본 연구는 대학원 이상의 고학력부모를 둔 자녀들이 그렇지 않은 집단 보다 게임중독성향을 더 높게 나타내는 이유를 탐색해 보기 위해 고학력이라는 부모의 속성에 직접 관련될 것으로 여겨지는 가족기능 및 의사소통 등 가족관련 심리사회적 변인들과 부모의 컴퓨터에 대한 효율적 통제와 관련된 맞벌이 여부, 컴퓨터설치장소, 여가활동을 주로 혼자 하는지 여부 등의 변인들이 게임중독에 미치는 영향을 알아보았다. 아버지가 고학력자인 자녀들의 경우는 일반가정에 비해 가족기능 등 각 변인들의 평균점수가 일반가정에 비해 대체로 양호함에도 불구하고 게임중독성향이 높게 나타난다. 집단별로 회귀분석을 실시한 결과 이 집단에서는 어머니의 문제형 의사소통과 컴퓨터가 자기방에 있는지 여부가 게임중독성향에 유의미한 영향을 미치는 것으로 나타났다. 반면 아버지가 고학력이 아닌 일반집단에서는 심리사회적 변수들과 맞벌이 여부, 주로 혼자 여가를 보내는지 여부, 성적, 성별 등이 모두 유의미한 것으로 나타나 아버지가 고학력인 상층에서는 이들 변수들을 해결하고 통제하는 능력이 일반적인 집단에 비해 큰 것으로 짐작된다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권2호
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• pp.793-796
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• 2015

Background: Chronic lymphoid leukemia (CLL) is not an uncommon hematological malignancy which primarily affects elderly individuals. It is more common in developed world than in developing countries. The rational of this study was to determine the clinico-hematological profile in Pakistan. Materials and Methods: In this prospective cross sectional study, sixty patients with CLL were enrolled from January 2011 to June 2013. Data were analyzed with SPSS version 21. Results: The mean age was $59.0{\pm}9.2years$ (range 40-82) and the male to female ratio was 2.1:1. Peak age group was 60-70 years (38.3%) and 18.3% were under 50 years old. Major complaints were weakness (51.7%), fever (18.3%) and abdominal discomfort (13.3%). Main clinical findings were splenomegaly (46.6%), lymphadenopathy (36.6%) and pallor (26.7%). Some 16.7% were diagnosed incidentally. The mean hemoglobin was $10.8{\pm}2.4g/dl$, with a total leukocyte count of $91.5{\pm}87.8{\times}10^9/l$ and platelets $197.8{\pm}103.2{\times}10^9/l$. Anemia and thrombocytopenia were seen in 26.7% and 21.7% of cases, respectively. High LDH and hyperuricemia were detected in 15% each and elevated serum creatinine was seen in 11.6%. According to Rai staging 11.6% were in stage 0, 13.3% stage 1, 26.7% each for stage II and stage III while 21.7% patients were in stage IV. Conclusions: CLL in our patients in Pakistan, unlike in the West, is seen in a relatively young population with male predominance. Primarily disease is of B-cell origin and about 2/3 of the patients present at advanced stage.

• Journal of Magnetics
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• 제13권2호
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• pp.37-42
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• 2008

In this paper, design parameters of high Q (> 50), high current inductor for on-chip power module were optimized by 4 Xs 3 Ys DOE (Design of Experiment). Coil spacing, coil thickness, ferrite thickness, and permeability were assigned to Xs, and inductance (L) and Q factor at 10 MHz, and resonance frequency ($f_r$) were determined Ys. Effects of each X on the Ys were demonstrated and explained using known inductor theory. Multiple response optimizations were accomplished by three derived regression equations on the Ys. As a result, L of 125 nH, Q factor of 197.5, and $f_r$ of 316.3 MHz were obtained with coil space of $127\;{\mu}m$, Cu thickness of $67.8\;{\mu}m$, ferrite thickness of $130.3\;{\mu}m$, and permeability 156.5. Loss tan ${\delta}=0$ was assumed for the estimation. Accordingly, Q factor of about 60 is expected at tan ${\delta}=0.02$.

• 한국융합학회논문지
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• 제9권1호
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• pp.189-197
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• 2018

본 연구는 다문화 가정 청소년의 정신건강 중 우울과 사회부적응에 미치는 영향요인을 규명하여 건강증진 프로그램개발 및 정책개발의 기초자료를 제공하고자 시도되었다. 연구대상은 211명의 다문화 가정 청소년으로 자기보고식 질문지 방법으로 수집되었으며 자료분석은 SPSS 23. 프로그램에 의해 위계적 회귀분석을 사용하였다. 연구결과를 보면 스트레스, 진로성숙도와 부모의 권위주의적 양육태도가 우울에 중요한 영향력을 보여주었다. 또한 사회적 부적응에는 스트레스, 권위주의적인 양육태도가 부정적 영향을, 탄력성, 진로성숙도와 문화다양성 태도, 개방적 의사소통과 부모의 지지가 긍정적 영향을 주었다. 본 연구는 다문화 가정 청소년에 대한 이해와 우울과 사회부적응 등 정신건강을 위한 개입프로그램 개발에 대한 기초자료를 제공할 수 있다.

• Asian Pacific Journal of Cancer Prevention
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• 제13권7호
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• pp.3319-3323
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• 2012

Objective: The results from the published studies on the association between prohibitin 3' untranslated region C > T gene polymorphism and cancer risk are conflicting. This meta-analysis was performed to evaluate the relationship with cancer susceptibility overall, and to explore whether the T allele or TT genotype could become a predictive marker for cancer risk. Methods: Association studies were identified from the databases of PubMed, Embase, and Cochrane Library as of March 1, 2012, and eligible investigations were synthesized using the meta-analysis method. Results were expressed with odds ratios (OR) for dichotomous data, and 95% confidence intervals (CI) were also calculated. Results: Six investigations were identified for the analysis of association between the prohibitin 3' untranslated region C > T gene polymorphism and cancer risk, covering of 1,461 patients with cancer and 1,197 controls. There was a positive association between the T allele and cancer susceptibility (OR=1.20, 95% CI: 1.03-1.39, P=0.02), and CC homozygous might play a protective role (OR=0.80, 95% CI: 0.68-6.11, P=0.95). In the sub-group analysis, prohibitin 3' untranslated region C > T gene polymorphism and cancer risk appeared associated with the risk of breast cancer, but not ovarian cancer. Conclusions: Our results indicate that T allele is a significant genetic molecular marker to predict cancer susceptibility and CC genotype is protective, especially for breast cancer. However, more investigations are required to further clarify the association of the prohibitin 3' untranslated region C > T gene polymorphism with cancer susceptibility.

• Asian Pacific Journal of Cancer Prevention
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• 제13권5호
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• pp.2171-2174
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• 2012

Background: Pancreatic cancer is a distressing disease with a miserable prospects and early recognition remains a challenge due to ubiquitous symptomatic presentation, deep anatomical location, and aggressive etiology. False positives and problems in distinguishing pancreatitis from adenocarcinoma limit the use of CA 19-9 as both disorders can present with similar symptoms and share radiographic physiognomies. This study aimed to assess the relative increase in accuracy of diagnosing the patients with chronic pancreatitis, benign neoplasm of pancreas and adenocarcinomas with CA 19-9, haptoglobin, and serum amyloid A in comparison to CA 19-9 alone. Materials and Methods: This hospital based case control study was carried out in the Departments of Medicine and Biochemistry of Manipal Teaching Hospital, Pokhara, Nepal, between $1^{st}$ January 2010 and $31^{st}$ December 2011. The variables assessed were age, gender, serum CA19-9, serum haptoglobulin, serum Amyloid A. The data were analyzed using Excel 2003, R 2.8.0 Statistical Package for the Social Sciences (SPSS) for Windows Version 16.0 (SPSS Inc; Chicago, IL, USA) and the EPI Info 3.5.1 Windows Version. Results: Out of 197 cases of pancreatic disease, maximum number of assumed cases were of adenocarcinoma of pancreas (95). Number of males (59) were more than females (36) in assumed cases of adenocarcinoma of pancreas. The mean values of CA19-9 raised considerably in cases of chronic pancreatitis, benign neoplasm and adenocarcinoma of pancreas when compared to controls. The highest augmention in CA19-9 values were in cases of adenocarcinoma of pancreas. The p-value indicates that in cases of chronic pancreatitis, there was not significant increase in precision of diagnosis. Conclusions: These statistics established that haptoglobin and SAA are useful in discriminating cancer from benign conditions as well as healthy controls.

• 한국습지학회지
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• 제13권2호
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• pp.189-197
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• 2011

본 논문에서는 지상강우의 결측치를 추정하는 방법들 중 역거리 가중치법(IDWM), 역지수 가중치법(IEWM), 상관계수가중치법(CCWM), 인공신경망(ANN)기법, 레이더 자료를 이용한 결측치 추정 방법을 비교하여 각각의 적용성을 검토하였다. 임진강 유역을 대상지역으로 하여 각 방법을 적용한 결과, 강우의 결측치 추정에 있어서 기존의 방법 중 상관계수 가중치법(CCWM)과 인공신경망(ANN)기법에 의한 RMSE가 0.46~1.79의 범위를 보였고, 레이더자료를 이용하여 강우의 결측치를 추정한 경우 RMSE가 0.05~2.26의 범위를 보였다. 레이더 강우자료가 지점 강우자료와 달리 강우의 공간상관성을 반영하고 있음을 볼 때, 지점강우 자료를 이용한 결측치 추정 기법보다 레이더자료를 이용한 결측치의 추정기법이 그 적용성에서 우수하다고 판단되어진다.

• 전기화학회지
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• 제13권3호
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• pp.193-197
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• 2010

In terms of the system efficiency, it is very useful to apply the ejector into the fuel recirculation system of a fuel cell system since the ejector needs no parasitic power to operate. Since the conventional automotive fuel cell use hydrogen and air as their fuel, the only hydrogen is needed to be recirculated for the better fuel efficiency. On the other hand, the submarine fuel cell needs both hydrogen and oxygen recirculation systems because the submarine drives under the sea. In particular, the cathodic recirculation has to meet the tougher target since the oxygen based pressurized stack generally used in the submarine applications generates the significant amount of the water in the stack during the operation. Namely, the oxygen utilization has designed less than 50% in the whole operating range for the better exhausting of the generated waters. And thereby in terms of the oxygen utilization, the entrainment ratio of the ejector should be more than 1 within the whole operating range. However, the conventional ejector using a constant nozzle can not afford to satisfy the mentioned critical requirement. To overcome the problem, the dual-ejector and its control strategy are designed. The performance of the proposed dual-ejector is verified by the experiments based on the real operating conditions of the target submarine system. Furthermore, the proposed design method can be used for the other fuel recirculation system of a large-scale fuel cell system with the critical requirement of the fuel utilization.

• 품질경영학회지
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• 제48권1호
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• pp.13-27
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• 2020

Purpose: The purpose of this study is to present a recoil measurement and analysis of K2 rifle for the development of a virtual reality marksmanship training in the Republic of Korea Army. Methods: For the recoil measurement, a test-bed is built by a barrel that has exact dimensions of K2 rifle and three piezoelectric pressure sensors mounted on the barrel. Data of over 200 rounds of 5.56mm M193 and K100 bullets are collected and analyzed from live fire experiments. For the recoil analysis, both the free recoil method and the gas exhaust aftereffect method are used to calculate a recoil velocity, momentum and kinetic energy of K2 rifle by applying the law of conservation of momentum. In addition, a new method is proposed that uses the third law of motion and the chamber pressure model for the recoil measurement Results: The results show how different between the previous and proposed methods with respect to M193 and K100 bullets of K2 rifle. In M193, the free recoil method demonstrates 1.113, 4.197, and 2.335, the gas exhaust aftereffect method computes 1.698, 6.407, and 5.441, and the proposed method calculates 0.990, 3.734, and 1.848 in recoil velocity, momentum and kinetic energy, respectively. In K100, the free recoil method demonstrates 1.190, 4.487, and 2.669, the gas exhaust aftereffect method computes 1.776, 6.699, and 5.949, and the proposed method calculates 1.060, 3.998, and 2.119 in recoil velocity, momentum and kinetic energy, respectively. Conclusion: This study implements live fire experiments to provide recoil velocity, momentum, and kinetic energy of K2 rifle using both M193 and K100 bullets. For the development of the army virtual reality marksmanship, the results in this paper would be useful to design and produce a gun and/or a rifle of virtual reality.