• Title/Summary/Keyword: Y197-13

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In Vitro Fertilization and Development of Frozen-thawed Bovine Follicular Oocytes (동결융해 소 난포란의 체외발생에 관한 연구)

  • 윤종택;이호준;한기영
    • Journal of Embryo Transfer
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    • v.13 no.2
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    • pp.191-197
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    • 1998
  • Immature nocytes and in VitrO matured Oocytes collected from the slaughtered Korean cattle were frozen slowly with 10% ethylene glycol+5% polyvinyl pyrolidine+0.05M trehalose (l0EPT), 10% ethylene glycol+5% ficoll+0.05M sucrose (1OEFS), or 10% ethylene glycol+5% ficoll+0.05M trehalose (l0EFT) by cell freezer (experiment 1). And also,They were ultra-rapidly frozen with 30% ethylene glycol+10% polyvinyl pyrolidine+0.5M trehalose (3OEPT) or 30% ethylene glycol+18% ficoll+0.5M sucrose (3OEFS) using electron microscope grid (experiment 2). In experiment 1, the cleavage rate was 23.0% when immature oocytes were frozen slowly using various cryoprotectants descrihed above, and 5.1% of cleaved oocytes developed to over morula stage after in Vitro fertilization (IVF). There were no significant differences among these groups. When matured oocytes were frozen slowly, the total cleavage rate was 19.7%, and over morula stage was 3.2%. lOEPT (4.8%) and EFS (4.4%) were slightly more effective than l0EFT (0.0%) for development in vitro. Only in l0EFT treated group, immature oocytes have higher developmental capacity than matured ones, when they were frozen slowly and IVF after thawing. In experiment 2, oocytes were ultra-rapidly frozen using the electron microscope grid with two kind of cryoprotectants described above. In immature oocyte group, the cleavage rate was 13.9% and 5.8% of cleaved oocytes developed to over morula stage after IVF, and in matured group, 25.7 and 7.6%, respectively. There were no significant differences between two kind of cryoprotectants, but in ultra-rapid freezing using electron microscope grid, the efficiency is slightly higher in matured oocyte group.

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Tendencies toward Game Addiction in the Group of Adolescents with Highly-educated Parents (고학력부모를 둔 청소년의 게임중독 성향)

  • Kim, Hee-Ja
    • The Journal of the Korea Contents Association
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    • v.13 no.3
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    • pp.184-197
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    • 2013
  • The purpose of this study is to research the reason of higher tendencies toward game addiction in the group of adolescents with highly educated parents than the group of adolescents with non-highly educated parents. The results show that the variables affecting adolescents' game addiction in the group of adolescents with highly educated parents are very different with those in the group of adolescents with non-highly educated parents. In the group of adolescents with highly educated parents, most of variables related to family function and communication types are not significantly affecting game addiction, while they are affecting in the group of adolescents with non-highly educated parents. This indicates that highly educated families might have particular family system related to stratification culture.

Clinico-Hematological Profile of Patients with B-Chronic Lymphoid Leukemia in Pakistan

  • Zeeshan, Rozina;Sultan, Sadia;Irfan, Syed Muhammad;Kakar, Jamaludin;Hameed, Muhammad Asif
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.2
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    • pp.793-796
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    • 2015
  • Background: Chronic lymphoid leukemia (CLL) is not an uncommon hematological malignancy which primarily affects elderly individuals. It is more common in developed world than in developing countries. The rational of this study was to determine the clinico-hematological profile in Pakistan. Materials and Methods: In this prospective cross sectional study, sixty patients with CLL were enrolled from January 2011 to June 2013. Data were analyzed with SPSS version 21. Results: The mean age was $59.0{\pm}9.2years$ (range 40-82) and the male to female ratio was 2.1:1. Peak age group was 60-70 years (38.3%) and 18.3% were under 50 years old. Major complaints were weakness (51.7%), fever (18.3%) and abdominal discomfort (13.3%). Main clinical findings were splenomegaly (46.6%), lymphadenopathy (36.6%) and pallor (26.7%). Some 16.7% were diagnosed incidentally. The mean hemoglobin was $10.8{\pm}2.4g/dl$, with a total leukocyte count of $91.5{\pm}87.8{\times}10^9/l$ and platelets $197.8{\pm}103.2{\times}10^9/l$. Anemia and thrombocytopenia were seen in 26.7% and 21.7% of cases, respectively. High LDH and hyperuricemia were detected in 15% each and elevated serum creatinine was seen in 11.6%. According to Rai staging 11.6% were in stage 0, 13.3% stage 1, 26.7% each for stage II and stage III while 21.7% patients were in stage IV. Conclusions: CLL in our patients in Pakistan, unlike in the West, is seen in a relatively young population with male predominance. Primarily disease is of B-cell origin and about 2/3 of the patients present at advanced stage.

Optimized Design of Low Voltage High Current Ferrite Planar Inductor for 10 MHz On-chip Power Module

  • Bae, Seok;Hong, Yang-Ki;Lee, Jae-Jin;Abo, Gavin;Jalli, Jeevan;Lyle, Andrew;Han, Hong-Mei;Donohoe, Gregory W.
    • Journal of Magnetics
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    • v.13 no.2
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    • pp.37-42
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    • 2008
  • In this paper, design parameters of high Q (> 50), high current inductor for on-chip power module were optimized by 4 Xs 3 Ys DOE (Design of Experiment). Coil spacing, coil thickness, ferrite thickness, and permeability were assigned to Xs, and inductance (L) and Q factor at 10 MHz, and resonance frequency ($f_r$) were determined Ys. Effects of each X on the Ys were demonstrated and explained using known inductor theory. Multiple response optimizations were accomplished by three derived regression equations on the Ys. As a result, L of 125 nH, Q factor of 197.5, and $f_r$ of 316.3 MHz were obtained with coil space of $127\;{\mu}m$, Cu thickness of $67.8\;{\mu}m$, ferrite thickness of $130.3\;{\mu}m$, and permeability 156.5. Loss tan ${\delta}=0$ was assumed for the estimation. Accordingly, Q factor of about 60 is expected at tan ${\delta}=0.02$.

A Convergent Study on Factors Influencing Adolescents' Mental Health of Multicultural Family (다문화가정 청소년의 정신건강에 영향을 미치는 요인에 대한 융합연구)

  • Kim, Min-Kyeong
    • Journal of the Korea Convergence Society
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    • v.9 no.1
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    • pp.189-197
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    • 2018
  • The purpose of this study was to identify the influence the depression and social maladjustment in adolescence of multi_cultural families. The participants were 211 adolescents in multicultural family. The data were collected using a self-report questionnaire. Data analysis was performed using hierarchical regression with the SPSS 23.0 program. The stress, career maturity and authoritarian caring attitude had a significant impact on depression(F=13.77, p<.001). The stress, authoritarian caring attitude, negative impact and resilience, career maturity, cultural diversity attitude, open communication, parents' support showed positive impact on social maladaptation(F=13.77, p<.001). This study contributes an integrated understanding of adolescents in multicultural family. And the findings was provided basic data for the development of intervention program on depression and social maladjustment for adolescents in multicultural family.

Relationship Between the Prohibitin 3' Untranslated Region C > T Gene Polymorphism and Cancer Susceptibility - Results of a Meta-analysis

  • Zhou, Tian-Biao;Yin, Sheng-Sheng;Huang, Jian-Jian;Ou, Chao
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.7
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    • pp.3319-3323
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    • 2012
  • Objective: The results from the published studies on the association between prohibitin 3' untranslated region C > T gene polymorphism and cancer risk are conflicting. This meta-analysis was performed to evaluate the relationship with cancer susceptibility overall, and to explore whether the T allele or TT genotype could become a predictive marker for cancer risk. Methods: Association studies were identified from the databases of PubMed, Embase, and Cochrane Library as of March 1, 2012, and eligible investigations were synthesized using the meta-analysis method. Results were expressed with odds ratios (OR) for dichotomous data, and 95% confidence intervals (CI) were also calculated. Results: Six investigations were identified for the analysis of association between the prohibitin 3' untranslated region C > T gene polymorphism and cancer risk, covering of 1,461 patients with cancer and 1,197 controls. There was a positive association between the T allele and cancer susceptibility (OR=1.20, 95% CI: 1.03-1.39, P=0.02), and CC homozygous might play a protective role (OR=0.80, 95% CI: 0.68-6.11, P=0.95). In the sub-group analysis, prohibitin 3' untranslated region C > T gene polymorphism and cancer risk appeared associated with the risk of breast cancer, but not ovarian cancer. Conclusions: Our results indicate that T allele is a significant genetic molecular marker to predict cancer susceptibility and CC genotype is protective, especially for breast cancer. However, more investigations are required to further clarify the association of the prohibitin 3' untranslated region C > T gene polymorphism with cancer susceptibility.

Improved Diagnostic Accuracy of Pancreatic Diseases with a Combination of Various Novel Serum Biomarkers - Case Control Study from Manipal Teaching Hospital, Pokhara, Nepal

  • Farooqui, Mohammad Shamim;Mittal, Ankush;Poudel, Bibek;Mall, Suhas Kumar;Sathian, Brijesh;Tarique, Mohammad;Farooqui, Mohammad Hibban
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.5
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    • pp.2171-2174
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    • 2012
  • Background: Pancreatic cancer is a distressing disease with a miserable prospects and early recognition remains a challenge due to ubiquitous symptomatic presentation, deep anatomical location, and aggressive etiology. False positives and problems in distinguishing pancreatitis from adenocarcinoma limit the use of CA 19-9 as both disorders can present with similar symptoms and share radiographic physiognomies. This study aimed to assess the relative increase in accuracy of diagnosing the patients with chronic pancreatitis, benign neoplasm of pancreas and adenocarcinomas with CA 19-9, haptoglobin, and serum amyloid A in comparison to CA 19-9 alone. Materials and Methods: This hospital based case control study was carried out in the Departments of Medicine and Biochemistry of Manipal Teaching Hospital, Pokhara, Nepal, between $1^{st}$ January 2010 and $31^{st}$ December 2011. The variables assessed were age, gender, serum CA19-9, serum haptoglobulin, serum Amyloid A. The data were analyzed using Excel 2003, R 2.8.0 Statistical Package for the Social Sciences (SPSS) for Windows Version 16.0 (SPSS Inc; Chicago, IL, USA) and the EPI Info 3.5.1 Windows Version. Results: Out of 197 cases of pancreatic disease, maximum number of assumed cases were of adenocarcinoma of pancreas (95). Number of males (59) were more than females (36) in assumed cases of adenocarcinoma of pancreas. The mean values of CA19-9 raised considerably in cases of chronic pancreatitis, benign neoplasm and adenocarcinoma of pancreas when compared to controls. The highest augmention in CA19-9 values were in cases of adenocarcinoma of pancreas. The p-value indicates that in cases of chronic pancreatitis, there was not significant increase in precision of diagnosis. Conclusions: These statistics established that haptoglobin and SAA are useful in discriminating cancer from benign conditions as well as healthy controls.

The Comparison of Estimation Methods for the Missing Rainfall Data with spatio-temporal Variability (시공간적 변동성을 고려한 강우의 결측치 추정 방법의 비교)

  • Kim, Byung-Sik;Noh, Hui-Seong;Kim, Hung-Soo
    • Journal of Wetlands Research
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    • v.13 no.2
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    • pp.189-197
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    • 2011
  • This paper reviewed application of data-driven method, distance-weighted method(IDWM, IEWM, CCWM, ANN), and radar data method estimated of missing raifall data. To evaluate these methods, statistics was compared using radar and station rainfall data from Imjin-river basin. The range of RMSE values calculated for CCWM, ANN was 1.4 to 1.79mm, and the range of RMSE values estimated data used for radar rainfall data was 0.05 to 2.26mm. Spatial characteristics is considered to Radar rainfall data rather than station rainfall data. Result suggest that estimated data used for radar data can impove estimation of missing raifall data.

Cathodic Recirculation System Using a Dual-ejector to Improve Oxygen Utilization of a Submarine Fuel Cell

  • Kim, Min-Jin;Sohn, Young-Jun;Lee, Won-Yong
    • Journal of the Korean Electrochemical Society
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    • v.13 no.3
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    • pp.193-197
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    • 2010
  • In terms of the system efficiency, it is very useful to apply the ejector into the fuel recirculation system of a fuel cell system since the ejector needs no parasitic power to operate. Since the conventional automotive fuel cell use hydrogen and air as their fuel, the only hydrogen is needed to be recirculated for the better fuel efficiency. On the other hand, the submarine fuel cell needs both hydrogen and oxygen recirculation systems because the submarine drives under the sea. In particular, the cathodic recirculation has to meet the tougher target since the oxygen based pressurized stack generally used in the submarine applications generates the significant amount of the water in the stack during the operation. Namely, the oxygen utilization has designed less than 50% in the whole operating range for the better exhausting of the generated waters. And thereby in terms of the oxygen utilization, the entrainment ratio of the ejector should be more than 1 within the whole operating range. However, the conventional ejector using a constant nozzle can not afford to satisfy the mentioned critical requirement. To overcome the problem, the dual-ejector and its control strategy are designed. The performance of the proposed dual-ejector is verified by the experiments based on the real operating conditions of the target submarine system. Furthermore, the proposed design method can be used for the other fuel recirculation system of a large-scale fuel cell system with the critical requirement of the fuel utilization.

A Study on K2 Rifle Recoil Measurement and Analysis for Virtual Reality Marksmanship (가상현실 사격훈련을 위한 탄종별 K2 소화기의 주퇴산출 및 분석 연구)

  • Kim, Jong-Hwan;Jin, Youngho;Kwak, Yunki
    • Journal of Korean Society for Quality Management
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    • v.48 no.1
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    • pp.13-27
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    • 2020
  • Purpose: The purpose of this study is to present a recoil measurement and analysis of K2 rifle for the development of a virtual reality marksmanship training in the Republic of Korea Army. Methods: For the recoil measurement, a test-bed is built by a barrel that has exact dimensions of K2 rifle and three piezoelectric pressure sensors mounted on the barrel. Data of over 200 rounds of 5.56mm M193 and K100 bullets are collected and analyzed from live fire experiments. For the recoil analysis, both the free recoil method and the gas exhaust aftereffect method are used to calculate a recoil velocity, momentum and kinetic energy of K2 rifle by applying the law of conservation of momentum. In addition, a new method is proposed that uses the third law of motion and the chamber pressure model for the recoil measurement Results: The results show how different between the previous and proposed methods with respect to M193 and K100 bullets of K2 rifle. In M193, the free recoil method demonstrates 1.113, 4.197, and 2.335, the gas exhaust aftereffect method computes 1.698, 6.407, and 5.441, and the proposed method calculates 0.990, 3.734, and 1.848 in recoil velocity, momentum and kinetic energy, respectively. In K100, the free recoil method demonstrates 1.190, 4.487, and 2.669, the gas exhaust aftereffect method computes 1.776, 6.699, and 5.949, and the proposed method calculates 1.060, 3.998, and 2.119 in recoil velocity, momentum and kinetic energy, respectively. Conclusion: This study implements live fire experiments to provide recoil velocity, momentum, and kinetic energy of K2 rifle using both M193 and K100 bullets. For the development of the army virtual reality marksmanship, the results in this paper would be useful to design and produce a gun and/or a rifle of virtual reality.