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Radiation Absorbed Dose Measurement after I-131 Metaiodobenzylguanidine Treatment in a patient with Pheochromycytoma (갈색세포종 환자에서 Medical Internal Radiation Dose법을 이용한 I-131 Metaiodobenzylguanidine 치료 후 흡수선량 평가)

  • Yang, Weon-Il;Kim, Byeung-Il;Lee, Jae-Sung;Lee, Jung-Rim;Choi, Chang-Woon;Lim, Sang-Moo;Hong, Sung-Woon
    • The Korean Journal of Nuclear Medicine
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    • v.33 no.4
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    • pp.422-429
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    • 1999
  • Purpose: The measurement of radiation absorbed dose is useful to predict the response after I-131 labeled metaiodobenzylguanidine (MIBG) therapy and determine therapy dose in patients with unresectable or malignant pheochromocytoma. We estimated the absorbed dose in tumor tissue after high dose I-131 MIBG in a patient with pheochromocytoma using a gamma camera and Medical Internal Radiation Dose (MIRD) formula. Materials and Methods: A 64-year old female patient with pheochromocytoma who had multiple metastases of mediastinum, right kidney and periaortic lymph nodes, received 74 GBq (200 mCi) of I-131 MIBG. We obtained anterior and posterior images at 0.5, 16, 24, 64 and 145 hours after treatment. Two standard sources of 37 and 74 MBq of I-131 were imaged simultaneously. Cummulated I-131 MIBG uptake in tumor tissue was calculated after the correction of background activity, attenuation, system sensitivity and count loss at a high count rate. Results: The calculated absorbed radiation dose was 32-63 Gy/ 74 GBq, which was lower than the known dose for tumor remission (150-200 Gy). follow-up studies at 1 month showed minimally reduced tumor size on computed tomography, and mildly reduced I-131 MIBG uptake. Conclusion: We estimated radiation absorbed dose after therapeutic I-131 MIBG using a gamma camera and MIRD formula, which can be peformed in a clinical nuclear medicine laboratory. Our results suggest that the measurement of radiation absorbed dose in I-131 MIBG therapy is feasible as a routine clinical practice that can guide further treatment plan. The accuracy of dose measurement and correlation with clinical outcome should be evaluated further.

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Can We Hear the Shape of a Noise Source\ulcorner (소음원의 모양을 들어서 상상할 수 있을까\ulcorner)

  • Kim, Yang-Hann
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.14 no.7
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    • pp.586-603
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    • 2004
  • One of the subtle problems that make noise control difficult for engineers is “the invisibility of noise or sound.” The visual image of noise often helps to determine an appropriate means for noise control. There have been many attempts to fulfill this rather challenging objective. Theoretical or numerical means to visualize the sound field have been attempted and as a result, a great deal of progress has been accomplished, for example in the field of visualization of turbulent noise. However, most of the numerical methods are not quite ready to be applied practically to noise control issues. In the meantime, fast progress has made it possible instrumentally by using multiple microphones and fast signal processing systems, although these systems are not perfect but are useful. The state of the art system is recently available but still has many problematic issues : for example, how we can implement the visualized noise field. The constructed noise or sound picture always consists of bias and random errors, and consequently it is often difficult to determine the origin of the noise and the spatial shape of noise, as highlighted in the title. The first part of this paper introduces a brief history, which is associated with “sound visualization,” from Leonardo da Vinci's famous drawing on vortex street (Fig. 1) to modern acoustic holography and what has been accomplished by a line or surface array. The second part introduces the difficulties and the recent studies. These include de-Dopplerization and do-reverberation methods. The former is essential for visualizing a moving noise source, such as cars or trains. The latter relates to what produces noise in a room or closed space. Another mar issue associated this sound/noise visualization is whether or not Ivecan distinguish mutual dependence of noise in space : for example, we are asked to answer the question, “Can we see two birds singing or one bird with two beaks?"

Impacts of Green Manure Crop and Charcoal Applications on Ginger Growth and Soil Properties (녹비작물 및 Charcoal 처리가 생강 생육 및 토양 특성에 미치는 영향)

  • Yang, Hong-Seok;Kim, Dong-Jin;Ahn, Byung-Koo;Lee, Jin-Ho
    • Korean Journal of Organic Agriculture
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    • v.22 no.3
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    • pp.503-519
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    • 2014
  • This study was conducted to investigate ginger growth and its nutrient uptake depending on changes of soil properties as affected by applications of green manure crop and/or charcoal in continuous cropping system. The green manure crops applied were barley and hairy vetch, and charcoal was additionally treated in selected plots as a soil conditioner. Experimental plots were prepared as Plot 1 (control), Plot 2 (barley of 8kg $10a^{-1}$), Plot 3 (hairy vetch of 12kg $10a^{-1}$), Plot 4 (charcoal of 1,000kg $10a^{-1}$ and barley 8kg $10a^{-1}$), and Plot 5 (charcoal of 1,000kg $10a^{-1}$ and hairy vetch of 12kg $10a^{-1}$) with two different soil conditions (high clay content, HCC and low clay content, LCC). When comparing selected chemical properties of soils before and after cultivating ginger plant, soil pH decreased from 6.9~8.1 to 6.8~7.6, and electrical conductivity (EC) also declined from $0.45{\sim}1.25dSm^{-1}$ to $0.30{\sim}0.61dSm^{-1}$. However, the content of soil organic matter (SOM) and total nitrogen (T-N) increased. Thus, the soil chemical properties were improved with the applications of green manures and charcoal. Also, macro- and micro-nutrient contents of ginger plants in the different plots were various between normal and diseased plants grown in soils with HCC and LCC. In particular, the concentration of manganese (Mn) was 3~4 folds higher in the diseased plant than in the normal plants. Ginger growth status and yield was relatively improved with the applications of green manures and charcoal as comparing with control plot. Especially in the Plot 4 with LCC, the ginger plant was not infected by root-rot disease.

Food Sources of the Ascidian Styela clava Cultured in Suspension in Jindong Bay of Korea as Determined by C and N Stable Isotopes (탄소 및 질소안정동위원소 조성에 의한 남해안 진동만 양식 미더덕의 먹이원 평가)

  • Moon, Changho;Park, Hyun Je;Yun, Sung Gyu;Kwak, Jung Hyun
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.19 no.4
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    • pp.302-307
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    • 2014
  • To examine the trophic ecology of the ascidian Styela clava in an aquaculture system of Korea, stable carbon and nitrogen isotopes were analyzed monthly in S. clava, coarse ($>20{\mu}m$, CPOM) and fine particulate organic matters ($0.7<<20{\mu}m$, FPOM). CPOM (means: $-18.5{\pm}1.2$‰, $9.3{\pm}0.7$‰) were significantly higher ${\delta}^{13}C$ and ${\delta}^{15}N$ values than those ($-20.5{\pm}1.5$‰, $8.4{\pm}0.5$‰) of FPOM. S. clava had mean ${\delta}^{13}C$ and ${\delta}^{15}N$ values of $-18.9({\pm}1.7)$‰ and $11.6({\pm}0.7)$‰, respectively. S. clava were more similar to seasonal variations in ${\delta}^{13}C$ and ${\delta}^{15}N$ values of FPOM than those of CPOM, suggesting that they rely largely on the FPOM as a dietary source. In addition, our results displayed that the relative importance between CPOM and FPOM as dietary source for the ascidians can be changed according to the availability of each component in ambient environment, probably reflecting their feeding plasticity due to non-selective feeding irrespective of particle size. Finally, our results suggest that dynamics of pico- and nano-size plankton (i.e., FPOM) as an available nutritional source to S. clava should be effectively assessed to maintain and manage their sustainable aquaculture production.

Effect of an Offshore Fish Culture System on the Benthic Polychaete Community (외해가두리 양식이 저서다모류군집에 미치는 영향)

  • Jung, Rae-Hong;Yoon, Sang-Pil;Kim, Youn-Jung;Lee, Won-Chan;Hong, Sok Jin;Park, Sung-Eun;Oh, Hyung Taik
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.18 no.4
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    • pp.195-205
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    • 2013
  • Excessive input of organic matters from fish cage farming has been considered as one of the major factors disturbing benthic ecosystem, especially in semi-enclosed coastal waters. Recently offshore aquaculture in the vicinity of Jeju-do has been introduced to minimize that kind of negative impact. This study was conducted to investigate the ecological impacts of offshore aquaculture on the macrobenthic polychaete communities. A total of ten sampling works were carried out for 28 months, spanning from 10 days after starting giving feed to 3 months after stopping giving feed. During the study period, mean current velocity was quite strong with the range of 50 cm/s to 70 cm/s. TOC of surface sediment was constantly low. Significant changes in polychaete community were detected just three months after starting giving feed, which were the increase of the number of species and density at all stations. Up to 18 months after the start of farming, the amount of feed provided played an important role in the fluctuation of the number of species and density, especially at 0 m and 10 m stations. After reducing the amount of feed provided, dominance of some opportunistic species within 10 m distance from fish cages still lasted to the end of aquaculture. However, opportunistic species disappeared 3 months after the end of farming, which indicated the sign of recovery from the disturbance. From these results, the amount of food input and the period of cultivation were critical factors disturbing polychaete community and ensuing changes in this offshore and oligotrophic waters as well. In addition, study on the changes of polychaete community structure before and after fish farming showed more detailed changes in benthic ecological state than geochemical approach did.

Long-term Changes of Bathymetry and Surface Sediments in the dammed Yeongsan River Estuary, Korea, and Their Depositional Implication (영산강 하구의 수심 및 표층 퇴적물 특성의 변화와 퇴적환경)

  • KIM, YOUNG-GIL;CHANG, JIN HO
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.22 no.3
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    • pp.88-102
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    • 2017
  • Long-term changes in bathymetry and grain size of surface sediments were investigated for understanding depositional sedimentary environments in the channelized Yeongsan River Estuary, Korea. The results revealed that an average depth of the estuary had decreased up to 2.1 m from 1982 to 2006, while it had increased to 0.3 m from 2006 to 2012. The rapid decrease of the water depth from 1982 to 2006 was due to the vast deposition of mud caused by the change of water course and flow velocity after the estuary was dammed. Meanwhile the increase of the water depth from 2006 to 2012 may be associated with multiple erosional processes, including a dredging at the southern part of the estuary and other erosions from the dike sluice expansion work. Considering the water-depth change and tidal-level variation in the study area, an depositional rate in the estuary is estimated to be 8~9 cm/yr for the last 2 decades (1982~2006). The sediments of Yeongsan River Estuary are largely composed of silt-clay mixtures: overall, silt is distributed mainly in the shallow area of the estuary edge, while clay is confined to the deep area of the estuary center. Mean grain size of the sediments is 6.0 Ø on average in 1997, 7.8 Ø on average in 2005 and 7.7 Ø on average in 2012, respectively, suggesting that the sediments became finer due to the increase of silt and clay contents in 1997~2005. Furthermore, several lines of evidences, including the comparison between the amounts of the sediment influx discharged from the Yeongsan River and the sediments in the estuary, and the changes in distribution pattern of silt and clay contents implying that they moved from offshore to estuary dike, indicate that the mud sediments are originated mainly from the offshore, not from the river.

The Impact of monsoon Rainfall (Changma) on the Changes of Water Quality in the Lower Nakdong River (Mulgeum) (장마기의 강우가 낙동강 하류 (물금) 수질에 미치는 영향)

  • Park, Sung-Bae;Lee, Sang-Kyun;Chang, Kwang-Hyeon;Jeong, Kwang-Suek;Joo, Gea-Jae
    • Korean Journal of Ecology and Environment
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    • v.35 no.3 s.99
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    • pp.160-171
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    • 2002
  • The impact of summer monsoon on water quality of the lower Nakdong River was evaluated during the summer (June-August) in 1997. Several limnological variables were measured in the interval of $1{\sim}3$ day using an automatic monitoring system (Hydrolab $Recorder^{TM}$) to detect water quality changes caused by rainfall on onehour basis. During the monsoon period (from late June to mid July), 5 times of major rainfall events of >50 mm were recorded in the river basin. Dynamic changes of water quality were observed during the monsoon, and the first rainfall event (June$25{\sim}27$) had a significant influence on the water quality at the lower part of the river. All Parameters were largely changed due to the first rain event, and the changed level was maintained until the end of monsoon period. Nutrient concentrations and turbidity increased and values of the other parameters were declined as a result of water dilution. This rainfall event, Changma, is a meteorological phenomenon caused by the East-Asian monsoon climate. The magnitude and frequency of the rainfall during the early monsoon play an important role in change of water quality and ecosystem characteristics of large river systems.

Hydro-meteorological Effects on Water Quality Variability in Paldang Reservoir, Confluent Area of the South-Han River-North-Han River-Gyeongan Stream, Korea (남·북한강과 경안천 합류 수역 팔당호의 수질 변동성에 대한 기상·수문학적 영향)

  • Hwang, Soon-Jin;Kim, Keonhee;Park, Chaehong;Seo, Wanbum;Choi, Bong-Geun;Eum, Hyun Soo;Park, Myung-Hwan;Noh, Hye Ran;Sim, Yeon Bo;Shin, Jae-Ki
    • Korean Journal of Ecology and Environment
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    • v.49 no.4
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    • pp.354-374
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    • 2016
  • This study explored spatiotemporal variability of water quality in correspondence with hydrometeorological factors in the five stations of Paldang Reservoir located in the Han River during 4 years from May 2012 to December 2015. Variability of basic water quality factors were largely related with seasonal fluctuations of hydrology. Temperature stratification occurred in the deep dam station, and prolonged hypoxia was observed during the draught year. Nitrogen nutrients were increased with decreasing inflow in which changing pattern of $NH_4$ reversed to $NO_3$ by the effect of treated wastewater effluent. Phosphorus increase was manifest during the period of high inflow or severe drought. Chl-a variation was reversely related with both flow change and AGP(algal growth potential) variations. Our study demonstrated that water quality variability in Paldang Reservoir was largely attributed to both natural and operational changes of inflow and outflow (including water intake) based on major pollution source of the treated wastewater (total amount of $472{\times}10^3m^3d^{-1}$) entering to the water system from watershed. In the process of water quality variability, meteorological (e.g., flood, typhoon, abnormal rainfall, scorching heat of summer) and hydrological factors (inflow and discharge) were likely to work dynamically with nutrients pulse, dilution, absorption, concentration and sedimentation. We underline comprehensive limnological study related to hydro-meteorolology to understand short- and long-term water quality variability in river-type large reservoir and suggest the necessity of P-free wastewater treatment for the effective measure of reducing pollution level of Paldang drinking water resource.

Development of an Automatic Liquid Feeder for Early Weaned Piglets (조기이유 자돈용 액상사료 자동급이기 개발)

  • 유용희;정일병;안정대;이덕수;강희설;최희철;전병수;박홍석
    • Journal of Animal Environmental Science
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    • v.7 no.1
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    • pp.1-12
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    • 2001
  • This study was conducted to develope an automatic liquid feeder for early weaning piglets and to test the efficacy of the system. The liquid feeder consists of water heating and discharge unit, dry diet storing and discharge unit, mixing and discharge unit, mixed liquid feed-delivering unit, and the central control part which control each unit, feeding frequency and the amount of feeding. For investigating the possibility of practical use, a feeding trial was carried out using eighteen three way crossbred piglets weaned on 19 days of age for the experimental period of six weeks. Experimental diet was provided in liquid form using the automatic liquid feeder for the first three weeks and in dry form for the later three weeks. The water heating and discharge unit exactly supplied warm water by 27 $m\ell$/s, into the mixing unit. The dry diet storing and discharge unit supplied dry feed by 3.7g/s, into the mixing unit. Being compared with the standard growth rate suggested by NRC, average daily gain of the piglets during the first three weeks of liquid feeding was lower by 10%, while it was higher during three weeks of dry feeding and over the whole experimental period by 24 and 17%, respectively. Feed/gain was 1.09, 2.14 and 1.89 for the first 3 weeks, later 3 weeks, and whole period, respectively. Diarrhea was observed for three days from day 3 to day 7 after feeding liquid diet, but no pig died of it. In conclusion, a preliminary test for the newly developed an automatic liquid feeder using 19 days of age weaning piglets showed that the unit was successfully operated without any major problems. Piglets raised on a liquid diet through the unit developed grew less during the first three weeks, but their growth and feed intake were greatly improved thereafter, indicating the developed automatic liquid feeder may be practically used in swine industry.

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Transfer and Validation of NIRS Calibration Models for Evaluating Forage Quality in Italian Ryegrass Silages (이탈리안 라이그라스 사일리지의 품질평가를 위한 근적외선분광 (NIRS) 검량식의 이설 및 검증)

  • Cho, Kyu Chae;Park, Hyung Soo;Lee, Sang Hoon;Choi, Jin Hyeok;Seo, Sung;Choi, Gi Jun
    • Journal of Animal Environmental Science
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    • v.18 no.sup
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    • pp.81-90
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    • 2012
  • This study was evaluated high end research grade Near infrared spectrophotometer (NIRS) to low end popular field grade multiple Near infrared spectrophotometer (NIRS) for rapid analysis at forage quality at sight with 241 samples of Italian ryegrass silage during 3 years collected whole country for evaluate accuracy and precision between instruments. Firstly collected and build database high end research grade NIRS using with Unity Scientific Model 2500X (650 nm~2,500 nm) then trim and fit to low end popular field grade NIRS with Unity Scientific Model 1400 (1,400 nm~2,400 nm) then build and create calibration, transfer calibration with special transfer algorithm. The result between instruments was 0.000%~0.343% differences, rapidly analysis for chemical constituents, NDF, ADF, and crude protein, crude ash and fermentation parameter such as moisture, pH and lactic acid, finally forage quality parameter, TDN, DMI, RFV within 5 minutes at sight and the result equivalent with laboratory data. Nevertheless during 3 years collected samples for build calibration was organic samples that make differentiate by local or yearly bases etc. This strongly suggest population evaluation technique needed and constantly update calibration and maintenance calibration to proper handling database accumulation and spread out by knowledgable control laboratory analysis and reflect calibration update such as powerful control center needed for long lasting usage of forage analysis with NIRS at sight. Especially the agriculture products such as forage will continuously changes that made easily find out the changes and update routinely, if not near future NIRS was worthless due to those changes. Many research related NIRS was shortly study not long term study that made not well using NIRS, so the system needed check simple and instantly using with local language supported signal methods Global Distance (GD) and Neighbour Distance (ND) algorithm. Finally the multiple popular field grades instruments should be the same results not only between research grade instruments but also between multiple popular field grade instruments that needed easily transfer calibration and maintenance between instruments via internet networking techniques.