• Parasites, Hosts and Diseases
• /
• 제41권2호
• /
• pp.81-87
• /
• 2003

The effects of anti-allergic drugs on intestinal mastocytosis and the expulsion of Neodiplostomum seoulense were observed in Sprague-Dawley rats, after oral infection with 500 metacercariae. The drugs used were hydroxyzine (a histamine receptor H$_1$ blocker), cimetidine (a H$_2$ blocker), cyclosporin-A (a helper T-cell suppressant), and prednisolone (a T- and B-cell suppressant). Infected, but untreated controls, and uninfected controls, were prepared. Worm recovery rate and intestinal mastocytosis were measured on weeks 1, 2, 3, 5, and 7 post-infection. Compared with the infected controls, worm expulsion was significantly (P < 0.05) delayed in hydroxyzine- and cimetidine-treated rats, despite mastocytosis being equally marked in the duodenum of all three groups. In the cyclosporin-A- and prednisolone-treated groups, mastocytosis was suppressed, but worm expulsion was only slightly delayed, without statistical significance. Our results suggest that binding of histamine to its receptors on intestinal smooth muscles is more important in terms of the expulsion of N. seoulense from rats than the levels of histamine alone, or mastocytosis.

• Parasites, Hosts and Diseases
• /
• 제38권2호
• /
• pp.51-57
• /
• 2000

Follow-up studies have been conducted every three years on the endemicity of Gymnophalloides seoi infection in a small coastal village of Chollanam-do (Province), Korea, since it was first known as an endemic area in 1994. Special attention was given to its egg laying capacity in the human host. In fecal examinations, the overall helminth egg and/or cyst positive rate was 78.7% (74/94) in 1997 and 76.6% (82/107) in 2000. Among them G. seoi eggs showed the highest rate; 71.3% (67/94) in 1997 and 72.0% (77/107) in 2000. The average number of eggs per gram of feces (EPG) was 1,015 in 1997, while a reduced rate of 353 was observed in 2000. In 1997, total of 320,677 adult flukes of G. seoi (av. 10,344/person, 94-69,125 in range) were collected from the diarrheic stools of 31 treated patients. The EPG/worm obtained from 21 cases ranged from 0.04 to 0.77 (av. 0.23), suggesting density-dependent constraints on the worm fecundity. The relationship between the worm burden (X) and EPG/worm (Y) can be expressed as $Y=0.42{\cdot}e{\cdot}^{-l.2x}(r=0.49)$. The results showed that G. seoi infection is persistently endemic in this village.

• Parasites, Hosts and Diseases
• /
• 제45권1호
• /
• pp.27-32
• /
• 2007

The status of Dirofilaria immitis infection was assessed in pet dogs of Busan, Korea, and chemoprophylactic effects of microfilaricidal medication were evaluated. A total of 294 pet dogs older than 6 mo were examined, 217 of which had been maintained indoors, and 77 had been kept outdoors. The $Snap^R$ kit and direct microscopic examinations of the peripheral blood were used. The mean overall parasite positive rates were 10.2% and 6.5%, respectively. Outdoor dogs evidenced adult worm infection rate of 31.2% and microfilaria infection rate of 18.2%. The indoor dogs, however, evidenced adult worm infection rate of 2.8% and microfilaria infection rate of 2.3%. The prevalence in males was more than 2 times that of females. The changing pattern of infection rates by age evidenced a gradual increase, from 2- to 6-year-old dogs, after which, a decrease in infection rates was noted. With regard to chemoprophylaxis, the infection rates of complete and incomplete chemoprophylaxis groups were found to be 2-3 times lower than that of the non-chemoprophylaxis group. The results of the present study indicate that the risk of exposure to D. immitis in pet dogs is quite high, particularly in male outdoor dogs, and chemoprophylactic measures were quite effective.

• Asian-Australasian Journal of Animal Sciences
• /
• 제10권6호
• /
• pp.679-682
• /
• 1997

A uniform group of 12 upgraded growing goats aged between 6.0 and 7.5 months were used in this study. They were divided into three groups of $T_1$, $T_2$ and $T_3$. Four animals were randomly allocated to each group. They were infected orally with three levels (0 larva, 5,000 larvae and 10,000 larvae) of infective Haemonchus contortus larvae. Before infection, all animals were housed in individual pens with concrete floors. They were provided with a uniform management. Total red blood cells (RBC) and total white blood cells (WBC) were measured by hemacytometric method. Results showed significant interaction effect of H. contortus infection and duration of infection on red blood cell counts. The RBC counts of animals in treatment groups 2 and 3 showed significantly lower values over the control group from the second fortnight to the end of the study. The overall mean RBC values of groups 1, 2 and 3 were 11.73, 9.70 and $9.12million/mm^3$ blood, respectively. H. contortus infection did not significantly influence the total leukocyte counts. Worm infection and duration of infection interaction was also absent on WBC counts. However, the time or duration of infection significantly influenced the WBC counts. Fecal egg counts showed patent infections in the infected animals which also indicated by postmortem worm counts.

• Parasites, Hosts and Diseases
• /
• 제50권2호
• /
• pp.143-146
• /
• 2012

Diphyllobothrium latum infections in 4 young Korean men detected from 2008 to 2012 are presented. Three were diagnosed based on spontaneously discharged strobila of the adult worm in their feces, and 1 case was diagnosed by finding the worm at colonoscopy examination in a local clinic. The morphologic characteristics of the gravid proglottid and eggs were consistent with D. latum. All patients were treated with praziquantel 15 mg/kg, and follow-up stool examinations were done at 2 months after the medication. The main clinical complaints were intermittent gastrointestinal troubles such as indigestion, abdominal distension, and spontaneous discharge of tapeworm's segments in their feces. The most probable source of infection was the flesh of salmon or trout according to a patient's past history. These are the 45th to 48th recorded cases diagnosed by the adult worm in the Republic of Korea since 1971.

• Parasites, Hosts and Diseases
• /
• 제22권2호
• /
• pp.181-189
• /
• 1984

우리나라산(전남 강진 및 경남 금해시)미꾸리에서 이전고무극구흡충(Echinostoma cinetorchis)의 피낭유충을 처음으로 검출하고 횐쥐에 감염시킨 후 성충을 얻어 종을 확인하였다. 또, 미꾸리의 피낭유충 감염상황과 횐쥐에서의 간단한 발육과정을 관찰하였다. 결과를 요약하면 다음과 같다. 1. 미꾸리 46마리중 5마리 (10.9%)에서 담낭유충이 검출되었고 감염된 미꾸리당 감염대은 평균 34.4개이었다. 피낭유충은 미꾸리의 후복벽에서만 발견되었다. 2. 실험감염 횐쥐에서 감염 6∼28일까지 총 충체회수률은 24.6%이었으며 감염기간이 길어짐에 따라 회수률은 감소되었다. 3. 충체는 두증과 두련(37∼38개)이 뚜렷하고 고환이 이전하거나 소실되는 점으로 보아 E. sinetorchis Ando et Ozaki, 1923로 동정되었다. 4. 충체의 발육은 감염6일부터 10일 사이에 가장현저하였으며 이 기간중 특히 생식기관의 발육이 비생식기관에 비해 빠르고 현저하였다. 이상의 결과로 볼 때 우리나라에서 미꾸리가 이전고구극구흡충의 제이중간숙주 역할을 하고 있음이 입증되었고 실험적으로 얻은 성충의 형태에서 고구의 이전 또는 소실이 종의 특성임이 재확인되었다.

• Parasites, Hosts and Diseases
• /
• 제51권1호
• /
• pp.37-42
• /
• 2013

Taeniasis is prevalent in all regions of Thailand, except the South. Infections were more frequently found in males than females of any age from 7-83 years. Taenia saginata is the most common species throughout the country. Taenia asiatica was reported only in the province of Kanchanaburi in the Central region. Co-infections, with Taenia solium and T. asiatica or T. solium and T. saginata, were found. Hybridization between T. asiatica and T. saginata is evidence that co-infection is never found between these 2 species. Finding more than 1 worm in a single patient was not entirely rare. Genetic variation was found without correlation to its geographic distribution in T. saginata, whereas no variation was found in T. asiatica.

• Parasites, Hosts and Diseases
• /
• 제53권6호
• /
• pp.725-730
• /
• 2015

We report here an ectopic case of Fasciola hepatica infection confirmed by recovery of an adult worm in the mesocolon. A 56-year-old female was admitted to our hospital with discomfort and pain in the left lower quadrant of the abdomen. Abdominal CT showed 3 abscesses in the left upper quadrant, mesentery, and pelvic cavity. On surgical exploration, abscess pockets were found in the mesocolon of the sigmoid colon and transverse colon. A leaf-like worm found in the abscess pocket of the mesocolon of the left colon was diagnosed as an adult fluke of F. hepatica. Histologically, numerous eggs of F. hepatica were noted with acute and chronic granulomatous inflammations in the subserosa and pericolic adipose tissues. Conclusively, a rare case of ectopic fascioliasis has been confirmed in this study by the adult worm recovery of F. hepatica in the mesocolon.

• 한국동물위생학회지
• /
• 제30권3호
• /
• pp.415-419
• /
• 2007

This study was carried out to investigate the prevalence of Ascaris suum infection of slaughtered pigs in Chungju and Eumseong area from January to June in 2007. The percentage of pigs and farms detected milk spot, adult worm, and adult worm in detected milk spot were 4.2% and 23.8%, 0.2% and 9.3%, and 4.9% and 39%, respectively. The prevalence of A suum infection from April to June 2007 was lower than that of January to March 2007. There is not enough of difference in farms' infection rate based on their breeding type.

• Parasites, Hosts and Diseases
• /
• 제36권2호
• /
• pp.109-120
• /
• 1998

서울주걱흡충 (Weodiplostomum seoulense)에 감염된 BALB/c 및 C3H 마우스의 소장에서 비만 세포 및 배세포 반응 양상을 관찰하고, 이들 반응이 숙주 방어기전 및 충체 배출에 영향을 줄 수 있는지 알아보았다. 마우스 1마리당 피낭유충 200개씩을 감염시킨 후 28일까지 충체회수율을 관 찰한 바 BALB/c 마우스가 C3H 마우스에 비해 월등히 높은 충체회수율을 보였다 그러나, 마우스 주에 관계없이 충체의 주 기생부위인 십이지장에서 감염 7일에 비만세포수가 최고에 달하였고 곧 바로 감소하였다. 이러한 비만세포수의 반응 양상은 공장 및 회장에서도 비슷하게 나타났으며, 반응의 강도는 십이지장이나 공장이 회장에 비해 높았다. 또한, 비만세포수의 최고치는 BALB/c 마우스에서 C3H 마우스보다 오히려 높게 나타났다. 배세포 증식은 BALB/c 마우스의 경우 감염 14 일을 제외하고는 십이지장에서 뚜렷이 관찰되었고, C3H 마우스의 경우에는 감염 7일에 공장 및 회장에서 관찰되었다. 배세포의 점액 (mucin) 활성은 BAkBlc 및 C3H 마우스 모두에서 인정되었으나, 그 강도는 BALBlc 마우스에서 더욱 뚜렷하였다. 이상의 결과를 종합할 때, 이들 마우스의 장점막 비만세포 및 배세포 반응은 서울주걱흡충 감염에 대한 국소적인 면역반응으로 나타나지만 숙주 방어나 충체 배출에의 관여도는 낮을 것으로 추측되었다.