• Title/Summary/Keyword: WindPRO

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Euphorbiae Humifusae Inhibits Egr-1, $NF{-\kappa}B$ and COX-2 Activity Stimulated by Phorbol 12-myristate-13-acetate (PMA에 의해 유도된 Egr-1, $NF{-\kappa}B$ 및 COX-2의 활성에 미치는 지금초 추출물의 영향)

  • Kim, Tae-Hwan;Jin, Cheng-Yun;Park, Sang-Eun;Kim, Won-Il;Park, Dong-Il;Kim, Gi-Young;Kim, Nam-Deuk;Hong, Sang-Hoon;Choi, Yung-Hyun
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.22 no.2
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    • pp.415-421
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    • 2008
  • Pro-inflammatory mediators, such as prostaglandin $E_2$ (PGE2), nitric oxide (NO), and cyclooxygenases-2 (COX-2), play pivotal roles in normal as well as transformed cells. Previous studies have shown that Euphorbiae humifusae Wind exhibits anti-proliferative and antioxidant activities. However, the it's anti-inflammatory properties are unclear. In this study, we examine the effects of water extract of E. humifusae (WEEH) on the expression of COX-2 and the production of $PGE_2$ in human lymphatic U937 cells. Treatment of phorbol 12-myristate-13-acetate (PMA) significantly induced COX-2 expression and $PGE_2$ production in U937 cells. However, pretreatment WEEH markedly inhibited the PMA-induced COX-2 expression and $PGE_2$ production in a dose-dependent manner. Moreover, WEEH prevented the elevated early growth response gene-1 (Egr-1) expression and nuclear factor-kappaB ($NF{-\kappa}B\; p65$) nuclear translocation stimulated by PMA treatment. Taken together, the present data indicate that WEEH exhibits anti-inflammatory properties by suppressing the transcription of pro-inflammatory cytokine genes through the $NF{-\kappa}B$ and Egr-1 signaling pathway.

Technical Status of Microwave Remote Sensing of Tropical Cyclones (열대저기압 마이크로파 원격탐사의 기술 현황)

  • Choi, Geun-Chul;Yang, Chan-Su;Pack, Han-Il
    • Proceedings of KOSOMES biannual meeting
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    • 2006.11a
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    • pp.193-199
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    • 2006
  • This article reviews several microwave instruments employed in observation and analysis of tropical cyclones (TCs), typhoon, and hurricanes. Microwave signals are useful for observing tropical cyclones with severe storms since it isn't severely absorbed by the clouds and rain in the storm. The instruments discussed include scatterometers, microwave radiometers, synthetic aperture radars (SARs), and rain radar from space. The date such as winds, rainfall and cloud-distribution in the TCs obtained by microwave instruments provide important informations for forecasting the intensity and path of the typhoon. For example, there're wind-distribution provided by SSM/I which has a wide swath, detailed wind fields from ERS-1, 2 scatterometers and RADARSAT-1 SAR and TRMM's rain radar pro 떠 ding high resolution. Operational satellite instruments lunched recently have improved upon the problems of low resolution and narrow swath indicated at the beginning microwave remote sensing. Understanding and practical using sufficiently about the microwave instruments will serve for searching the features such as generation and development of the TCs.

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Development of The Bean Threshing System using Independent Driving (독립구동방식의 콩 탈곡기 시스템 개발)

  • Jang, BongChoon;Kim, Sung-Chul
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.14 no.9
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    • pp.4124-4129
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    • 2013
  • This purpose of this research is to build up a prototype of bean threshing machine after three dimensional design which can be driven independently by engine and hydraulic equipments and wheels. To accomplish the functionality of bean threshing machine the cutters are placed in a swirl type on a threshing drum the thresing capability would be improved. Also a exit pipe was designed to clear the remains to solve the past problems that the normal machines had. A fan was designed to blow to send the waste only to the outside. Only clean beans will be transferred through a blowing fan wind power to exit pipe and the system was designed to help the worker to collect the beans in front of the machine. This threshing machine using independent driving engine which can provide the power to drive the system and do the threshing is the first developed technology in domestic area through the University and Industry cooperation.