• Communications for Statistical Applications and Methods
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• v.17 no.5
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• pp.689-696
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• 2010

Interval-censored data are commonly found in studies of diseases that progress without symptoms, which require clinical evaluation for detection. Several techniques have been suggested with independent assumption. However, the assumption will not be valid if observations come from clusters. Furthermore, when the cluster size relates to response variables, commonly used methods can bring biased results. For example, in a study on lymphatic filariasis, a parasitic disease where worms make several nests in the infected person's lymphatic vessels and reside until adulthood, the response variable of interest is the nest-extinction times. Since the extinction times of nests are checked by repeated ultrasound examinations, exact extinction times are not observed. Instead, data are composed of two examination points: the last examination time with living worms and the first examination time with dead worms. Furthermore, as Williamson et al. (2008) pointed out, larger nests show a tendency for low clearance rates. This association has been denoted as an informative cluster size. To analyze the relationship between the numbers of nests and interval-censored nest-extinction times, this study proposes a joint model for the relationship between cluster size and clustered interval-censored failure data.

• 한국방재학회:학술대회논문집
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• 2011.02a
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• pp.69-69
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• 2011

본 논문에서는 비정상 상태의 비압축성 유동장을 해석하기 위하여 물체맞춤격자방법이 아닌 가상경계법을 사용하였다. 가상경계법은 구조격자를 사용하여 구조물 경계면에서 Momentum Forceing을 사용하여 가상의 경계를 만들어 유동장을 해석하는 방법이다. Navier-Stoke 방정식의 수치 이산화 방법으로 Kim et al(1985)이 사용한 Fractional Step Method(FSM)을 사용하였다. 시간에 대하여 semi-implicit FSM를 사용하였고, 확산항에 대해서는 2차 정확도의 Crank-Nicolson Method를 대류항은 3차 정확도의 Runge-Kutta Method를 사용 하였다. 본 연구에서는 가상경계법을 이용한 유동장 해석이 교량 단면에 대하여 수치해석이 가능한지 검토하였다. 가상경계법은 현재 많은 연구가 유선형의 구조물에 대하여 수행되어 오고 있다. 교량 단면과 같은 각 진 구조물에 대한 검토는 아직 미비한 실정이다. 가상경계법에서 다루고 있는 구조물 경계면에서의 Momentum Forcing 방법이 유선형의 구조물에 맞추어 연구가 진행되었기 때문이다. 먼저 본 연구의 프로그램을 검증하기 위하여 원형 실린더에 대하여 가상경계법을 적용한 결과 Re 수 200에서 Strouhal Number, 양력계수, 항력계수를 이전 연구 결과와 비교하였다. Williamson(1988)과 Zhang(1995)의 연구결과와 유사한 결과를 얻을 수 있다. 그리고 교량의 단면과 같은 각진 구조물(Bluff Body)에 대하여 가상경계법 적용하였다. 본 논문의 연구에서 평가 대상으로 하고 있는 2차원 교량 단면에 대하여 유동장 해석을 하였다. 본 논문에서 정량적인 유체력과 유동장에 대한 비교 및 검토가 이루어지지 못했지만 압력장과 유선의 형태가 이론적인 값을 벗어나지 않고 있는 것으로 확인 되었다. Re 수 2700에서 전산 해석을 수행하였으며, 교량 단면 주위의 압력계수와 박리현상 그리고 후류에서의 Vortex shedding 현상이 모두 적절한 분포가 나타나는 것을 확인할 수 있었다. 따라서 가상경계법을 이용하여 각진 구조물에 대한 주위 유동장해석에 대한 가능성을 확인하였으며, 풍동실험과의 결과비교를 통하여 가상경계법을 이용하여 교량 단면 주위의 유동장 해석 결과를 정량적으로 비교할 것이다.

• Asian-Australasian Journal of Animal Sciences
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• v.2 no.2
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• pp.77-84
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• 1989

Twenty-four Hereford steers, 22 months old and a mean liveweight (${\pm}\;s.e.$) of $250\;{\pm}\;7\;kg$ were used in an experiment to evaluate over 42 days two rates of copra meal supplementation to cattle on a low N ($8.6\;{\pm}\;0.9$ g N/kg dry matter (DM)), low digestible ($45\;{\pm}\;5.2%$ DM) native pasture hay. Steers given the two rates (500, 1000 g/steer/day; i.e. 500C, 1000C) were compared to steers on a non-supplemental diet and to the effects on steers of supplemental urea (30g/steer/day; 30U) or with copra meal (500 g/steer/day; 500C.U), or of cottonseed meal (500 g/steer/day; 500S). Liveweight change was increased (P<0.01) by all of the supplements except by supplemental urea. The most effective treatment, 1000C, increased significantly (P<0.01) liveweight change (946 g/day) in steers above all supplements except those steers given 500C.U (718 g/day). Hay intake per unit liveweight was increased (P<0.05) by 7% by the 30U and 500C.U treatment, and by 9% by 500C; this group having the highest supplements, being greatest (P<0.05) for the 1000C group (6.0 g feed intake/g gain) and least for the 500S supplemented group (11.5 g/g gain). Efficiency was lowest (18.6 g/g gain) for the non-supplemented steers on the basal hay diet. Copra meal N was less degradable (i.e. 29%) in nylon bags over 15 hours in the rumen than was cottonseed meal N (37%), and rumen ammonia concentrations were lower (P<0.05) in cattle supplemented with copra meal (25, 27 mg N/L) than in cattle given urea (36 mg N/L) or cottonseed meal (39 mg N/L). It is concluded that copra meal at a daily rate of 500 g/head, and with rumen soluble nitrogen from urea, is an effective supplement for improving growth of cattle on a low quality forage.

• Asian-Australasian Journal of Animal Sciences
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• v.1 no.2
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• pp.107-114
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• 1988

Six steers of each breed type, Hereford ($H{\times}H$), Brahman ($B{\times}B$) and Brahman $\times$ Hereford ($B{\times}H$) were ranked on liveweight and allocated to three treatments, basal hay diet (Basal), Basal plus 1 kg/head/day of cottonseed meal (Basal + CSM) and Basal plus 1 kg/head/day of formaldehyde-treated sunflower meal, $Norpro^{(R)}$ (Basal + NPO). The hay was made from a pasture based predominantly on carpet grass (Axonopus affinus) growing in subtropical New South Wales, and had an estimated organic matter digestibility of 52% and a nitrogen (N) content of 7.8 g/kg dry matter (DM). The steers were accustomed to the Basal diet over 15 days and supplements offered over 42 days. Intake of the basal hay diet by steers was not increased by supplementation. When intakes were adjusted for differences between breed types in liveweight the $B{\times}H$ steers ate 25% (P<0.01) more hay than $H{\times}H$ steers (6.3 V 5.0 kg/head/d) and $B{\times}B$ steers ate 8% less hay than $H{\times}H$ steers. Supplementation significantly (P<0.01) increased liveweight gain during the experiment, being ($g/head/d\;{\pm}\;s.e.d.$) 290, 770 and $795{\pm}118$ respectively for Basal, Basal + NPO and Basal + CSM. There was no difference between supplements in the liveweight gain of steers nor between steers of different genotypes. However, there was a significant interaction (P<0.01) between breeds and treatments such that $B{\times}B$ steers gained most on the basal diet but least of the breed types when supplemented. The estimated non-degradeable fraction of N in the protein meals was 58.5 and 44.5%, respectively for NPO and CSM. Both meals increased (P<0.01) plasma urea N and rumen ammonia N concentrations.

• Journal of Distribution Research
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• v.12 no.1
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• pp.105-123
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• 2007

Recently, the beauty service industry in Korea is growing rapidly as women have increased role in society and consumers have more diversified desire for beauty. In that sense, studies on the environment of transaction is necessary to maintain the customers who use beauty service which Is one of the most prominent services in Korea. However, there is a lack of systematic investigation on that. Under those circumstances, this study tries to propose strategies by shedding light on the reasons of store loyalty based on empirical study. Furthermore, securing regular customers is deemed to be the most important thing as the competition among stores are getting fiercer in the wake of increase in the number of beauty salons. In that light, this study tries to shed light on the transaction cost clearly which affects the store loyalty, and focuses on the development of integrated research model for the transaction cost related to the environmental characteristics of beauty service industry and for the store loyalty.

• Tribology and Lubricants
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• v.34 no.1
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• pp.23-32
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• 2018

Coupling is a mechanical component that transmits rotational force by connecting two shafts. Curvic coupling is widely used in high-performance systems because of its excellent power transmission efficiency and easy machining. However, coupling applications change dynamic behavior by reducing the stiffness of an entire system. Contact surface stiffness is an important parameter that determines the dynamic behavior of a system. In addition, the roughness profile of a contact surface is the most important parameter for obtaining contact stiffness. In this study, we theoretically establish the process of contact and bending stiffness analysis by considering the rough surface contact at Curvic coupling. Surface roughness parameters are obtained from Nayak's random process, and the normal contact stiffness of a contact surface is calculated using the Greenwood and Williamson model in the elastic region and the Jackson and Green model in the elastic-plastic region. The shape of the Curvic coupling contact surface is obtained by modeling a machined shape through an actual machining tool. Based on this modeling, we find the maximum number of gear teeth that can be machined according to the contact angle. Curvic coupling stiffness is calculated by considering the contact angle, and the calculation process is divided into stick and slip conditions. Based on this process, we investigate the stiffness characteristics according to the contact angle.

• Radiation Oncology Journal
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• v.37 no.1
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• pp.13-21
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• 2019

Purpose: Glioblastoma (GBM) carries a high propensity for in-field failure despite trimodality management. Past studies have failed to show outcome improvements with dose-escalation. Herein, we examined trends and outcomes associated with dose-escalation for GBM. Materials and Methods: The National Cancer Database was queried for GBM patients who underwent surgical resection and external-beam radiation with chemotherapy. Patients were excluded if doses were less than 59.4 Gy; dose-escalation referred to doses ≥66 Gy. Odds ratios identified predictors of dose-escalation. Univariable and multivariable Cox regressions determined potential predictors of overall survival (OS). Propensity-adjusted multivariable analysis better accounted for indication biases. Results: Of 33,991 patients, 1,223 patients received dose-escalation. Median dose in the escalation group was 70 Gy (range, 66 to 89.4 Gy). The use of dose-escalation decreased from 8% in 2004 to 2% in 2014. Predictors of escalated dose were African American race, lower comorbidity score, treatment at community centers, decreased income, and more remote treatment year. Median OS was 16.2 months and 15.8 months for the standard and dose-escalated cohorts, respectively (p = 0.35). On multivariable analysis, age >60 years, higher comorbidity score, treatment at community centers, decreased education, lower income, government insurance, Caucasian race, male gender, and more remote year of treatment predicted for worse OS. On propensity-adjusted multivariable analysis, age >60 years, distance from center >12 miles, decreased education, government insurance, and male gender predicted for worse outcome. Conclusion: Dose-escalated radiotherapy for GBM has decreased over time across the United States, in concordance with guidelines and the available evidence. Similarly, this large study did not discern survival improvements with dose-escalation.

• Clinics in Shoulder and Elbow
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• v.26 no.2
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• pp.109-116
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• 2023

Background: Golf is a popular sport involving overhead activity and engagement of the rotator cuff (RC). This study aimed to determine to what level golfers were able to return to golf following RC repair, the barriers to them returning to golf and factors associated with their failure to return to golf. Methods: Patients preoperatively identifying as golfers undergoing RC repair at the study centre from 2012 to 2020 were retrospectively followed up with to assess their golf-playing status, performance and frequency of play and functional and quality of life (QoL) outcomes. Results: Forty-seven golfers (40 men [85.1%] and 7 women [14.9%]) with a mean age of 56.8 years met the inclusion criteria, and 80.1% were followed up with at a mean of 27.1 months postoperatively. Twenty-nine patients (76.3%) had returned to golf with a mean handicap change of +1.0 (P=0.291). Golf frequency decreased from a mean of 1.8 rounds per week preinjury to 1.5 rounds per week postoperatively (P=0.052). The EuroQol 5-dimension 5-level (EQ-5D-5L) index and visual analog scale (EQ-VAS) score were significantly greater in those returning to golf (P=0.024 and P=0.002), although functional outcome measures were not significantly different. The primary barriers to return were ipsilateral shoulder dysfunction (78%) and loss of the habit of play (22%). Conclusions: Golfers were likely (76%) to return to golf following RC repair, including mostly to their premorbid performance level with little residual symptomatology. Return to golf was associated with a greater QoL. Persistent subjective shoulder dysfunction (78%) was the most common barrier to returning to golf.

• Tribology and Lubricants
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• v.40 no.1
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• pp.8-16
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• 2024

This study conducts numerical modeling and eigen-analysis of a rod-fastened rotor, which is mainly used in aircraft gas turbine engines in which multiple disks are in contact through curvic coupling. Nayak's theory is adopted to calculate surface parameters measured from the tooth profile of the curvic coupling gear. Surface parameters are important design parameters for predicting the stiffness between contact surfaces. Based on the calculated surface parameters, elastoplastic contact analysis is performed according to the interference between two surfaces based on the Greenwood-Williamson model. The equivalent bending stiffness is predicted based on the shape and elastoplastic contact stiffness of the curvic coupling. An equation of motion of the rod-fastened rotor, including the bending stiffness of the curvic coupling, is developed. Methods for applying the bending stiffness of a curvic coupling to the equation of motion and for modeling the equation of motion of a rotor that includes both inner and outer rotors are introduced. Rotordynamic analysis is performed through one-dimensional finite element analysis, and each element is modeled based on Timoshenko beam theory. Changes in bending stiffness and the resultant critical speed change in accordance with the rod fastening force are predicted, and the corresponding mode shapes are analyzed.

• Journal of Radiation Protection and Research
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• v.23 no.4
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• pp.259-266
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• 1998

There are three different types of gynecological applicator sets available in microSelectron-high dose-rate(HDR) System by Nucletron; standard applicator set(SAS), standard shielded applicator set(SSAS), and Fletcher-Williamson applicator set(FWAS). Shielding effect of a SAS without shielding material was compared with that of a SSAS with shielding material made of stainless steel(density ${\varrho}=8,000kg/m^3$) at the top and bottom of each ovoid, and of a FWAS with shielding material made of tungsten alloy(density ${\varrho}=14,000kg/m^3$ at the top and bottom of each ovoid. The shielding effects to the rectum and bladder of these two shielded applicator sets were to be measured at reference points with an ion chamber and specially designed supporting system for applicator ovoids inside of the computerized 3-dimensional water phantom. To determine the middle point of two ovoids the measurement was performed with the reference tip of ion chamber placed at the same level and at the middle point from the two ovoids, while scanning the dose with the ion chamber on each side of ovoids. The doses to the reference points of rectum were measured at 20(Rl), 25(R2), 30(R3), 40(R4), 50(R5), and 60(R6) mm located posteriorly on the vertical line drawn from M5(the middle dwell position of ovoid), and the doses to the bladder were measured at 20(Bl), 30(B2), 40(B3), 50(B4), and 60(B5) mm located anteriorly on the vertical line drawn from M5. The same technique was employed to measure the doses on each reference point of both SSAS and FWAS. The differences of measured rectal doses at 25 mm(R2) and 30 mm(R3) between SAS and SSAS were 8.0 % and 6.0 %: 25.0% and 23.0 % between SAS and FWAS. The differences of measured bladder doses at 20 mm(Bl) and 30 mm(B2) between SAS and SSAS were 8.0 % and 3.0 %: 23.0 % and 17.0 % between SAS and FWAS. The maximum shielding effects to the rectum and bladder of SSAS were 8.0 % and 8.0 %, whereas those of FWAS were 26.0 % and 23.0 %, respectively. These results led to the conclusion that FWAS has much better shielding effect than SSAS does, and when SSAS and FWAS were used for gynecological intracavitary brachytherapy in microSelectron-HDR system, the dose to the rectum and bladder was significantly reduced to optimize the treatment outcome and to lower the complication rates in the rectum and bladder.