• Korean Journal of Construction Engineering and Management
• /
• v.13 no.5
• /
• pp.135-143
• /
• 2012

Constructing super-tall buildings is significantly different from constructing general ones in every technological and managerial aspects. Especially lift-car operations planning and management is one of core parts among various management techniques required during the course of the whole construction process of the super-tall buildings because vertical movements of physical resources enormously affect the efficiency of the construction processes. However, discrepancy between lifting plans and actual lifting operations causes serious efficiency problems. As an effort to solve the problem, this research suggests an improved method of estimating resource-based lifting load. The computing model developed as a result of this research facilitates more accurate computation of the total operation time and the maximum lifting capacity of the lift-cars. Further, this research can be developed as a decision support system for the total lift-car operations management.

• Korean Journal of Biological Psychiatry
• /
• v.25 no.2
• /
• pp.38-43
• /
• 2018

Objectives Dopamine dysregulation has been regarded as one of the core pathologies in patients with schizophrenia. Since dopamine synthesis capacity has found to be inconsistent in patients with schizophrenia, current classification of patients based on clinical symptoms cannot reflect the neurochemical heterogeneity of the disease. Here we performed new subtyping of patients with first-episode psychosis (FEP) through biotype-based cluster analysis. We specifically suggested basal ganglia structural changes as a biotype, which deeply involves in the dopaminergic circuit. Methods Forty FEP and 40 demographically matched healthy participants underwent 3T T1 MRI. Whole brain parcellation was conducted, and volumes of total 6 regions of basal ganglia have been extracted as features for cluster analysis. We used K-means clustering, and external validation was conducted with Positive and Negative Syndrome Scale (PANSS). Results K-means clustering divided 40 FEP subjects into 2 clusters. Cluster 1 (n = 25) showed substantial volume decrease in 4 regions of basal ganglia compared to Cluster 2 (n = 15). Cluster 1 showed higher positive scales of PANSS compared with Cluster 2 (F = 2.333, p = 0.025). Compared to healthy controls, Cluster 1 showed smaller volumes in 4 regions, whereas Cluster 2 showed larger volumes in 3 regions. Conclusions Two subgroups have been found by cluster analysis, which showed a distinct difference in volume patterns of basal ganglia structures and positive symptom severity. The result possibly reflects the neurobiological heterogeneity of schizophrenia. Thus, the current study supports the importance of paradigm shift toward biotype-based diagnosis, instead of phenotype, for future precision psychiatry.

• Journal of Korean Society of Industrial and Systems Engineering
• /
• v.38 no.1
• /
• pp.170-181
• /
• 2015

Generally, because individual agricultural product possesses its own distinctive characteristics and shows different characteristics at each stage of the agricultural supply chain, it is necessary to develop a proper enterprise architecture for managing information system. In this paper, we propose an enterprise architecture based on RFID/USN technology that can be used as a reference enterprise architecture for u-IT application in the agriculture sectors, which is called the u-Farm enterprise architecture with taking heterogeneous characteristics of agricultural products into account for. In addition, we also developed the RFID/USN middleware platform as a core infrastructure technology. Fo evaluation of the performance of the proposed u-Farm architecture and the RFID/USN middleware platform, the field-trial evaluation at the apple Agricultural Processing Center (APC) has been executed and the results shows that the proposed architecture and platform perform well in terms of information integration over the whole SCM process from the farming stage to delivering statge to the customers. It is expected that the proposed u-Farm enterprise architecture can be utilized as a standard information architecture, and the RFID/USN middleware platform can be a infrastructure platform for future u-IT based information technology applications and services in the agricultural environment.

• Nuclear Engineering and Technology
• /
• v.5 no.4
• /
• pp.291-309
• /
• 1973

Exposure rates due to leakage gamma-rays from operating reactors TRIGA Mark II and III were measured in a horizontal plane by means of scintillation spectrometry using a 3"$\times$3" cylindrical Nal(T1) detector associated with a 400 channel pulse height analyzer under varied conditions of reactor operation. In determining exposure rate due to the leakage gamma-rays at each point of measurement, Moriuchi's spectrum-exposure rate conversion theory was applied instead of using conventional responce matrix method which necessitates very complicated procedures to convert a spectrum into exposure rate. The results show that a basic pattern of "typical" spectrum of the reactor leakage gamma-rays is neither affected by thermal output of the reactor, nor influenced by overall attenuation in radiation intensity. It was indicated that he attenuation of the leakage gamma-rays in air in terms of exposure rate as a whole follows an exponential law, and the total exposure rate due to the leakage gamma-rays at a certain point is nearly proportional to thermal output of the reactor. The complexity in spectrum measured for a movable core reactor, TRIGA Mark III, was analyzed through spectrum resolution, and proper judgement of the leakage gamma-rays in a complex spectrum was discussed.ctrum was discussed.

• Journal of Korean Society of Industrial and Systems Engineering
• /
• v.34 no.4
• /
• pp.49-56
• /
• 2011

The Project of Jordan Research and Training Reactor (JRTR) officially launched in Aug. 2010. JRTR is the first made-in-Korea nuclear system to be built abroad by year 2015, and Korea Atomic Energy Research Institute (KAERI) is responsible for the design of major systems including the reactor core. While the PDCS (Project Document Control System) being operated by EPC company controls all the documents of the whole Project, KAERI is supposed to have its own system for KAERI documents. Meeting such a need; KAERI has implemented a document control for the JRTR Project into already existing ANSIM (KAERI Advanced Nuclear Safety Information Management) system. The documents of JRTR project to be controlled are defined in the PPM (Project Procedures Manual), QAP (Quality Assurance Procedure) and PEP (Project Execution Program). The ANSIM consists of the document management holder, document container holder and organization management holder. The document management holder, which is the most important part of ANSIM-JRTR, consists of the DDA (Document Distribution for Agreement), IOC (Inter-office Correspondence), PM Memo. (Project Manager Memorandum) and cover sheets of design documents. Other materials such as meeting minutes, sub-department materials and design information materials are stored in an independent COP (Community of Practice). This established computerized document control system, ANSIM, could lessen a burden for project management team and enhance the productivity as well.

• Journal of the Korea Safety Management & Science
• /
• v.19 no.1
• /
• pp.63-71
• /
• 2017

As the demand for automation (or autonmation) or clean workplace has grown, the interest in the knowledge and skill regarding safety is rising in manager duty. Moreover, the importance of severity rate of injury has increased due to the enlargement of industry scale, even safety management area has developed. Thus, it is important that production managers, the core of the line process, realize the safety in their production line, even if a safety manager acts as a staff. However, in the duty oriented National Competency Standard (NCS), the education about the safety duty of production management part is insufficient. According to NCS, it is calculated production managers receive only 6.7% of whole safety education regarding the duty related the safety management for production manager in mechanical industry. However, the ability in safety is more demanded from production managers as the concept of "production and safety" turns into the concept of "production with safety". And then in this paper, we will compare and analyze the safety management duty in Korean NCS and the safety management duty in State Leaders Connecting Learning to Work in US manufacturing industry, in terms of the duty of the production manage in mechanical industry (05). And, we will develop the safety duty education system for production manager, by classifying the safety education in domestic mechanical industry into knowledge education, skill education, and attitude education with using AHP(Analytic Hierarchy Process).

• Molecules and Cells
• /
• v.27 no.2
• /
• pp.251-255
• /
• 2009

Sepsis is the leading cause of death in critically ill patients. Today, around 60% of all cases of sepsis are caused by Gram-negative bacteria. The cell wall component lipopolysaccharide (LPS) is the main initiator of the cascade of cellular reactions in Gram-negative infections. The core receptors for LPS are toll-like receptor 4 (TLR4), MD-2 and CD14. Attempts have been made to antagonize the toxic effect of endotoxin using monoclonal antibodies against CD14 and synthetic lipopolysaccharides but there is as yet no effective treatment for septic syndrome. Here, we describe an inhibitory effect of a phosphatidylethanolamine derivative, PE-DTPA (phosphatidylethanolamine diethylenetriaminepentaacetate) on LPS recognition. PE-DTPA bound strongly to CD14 ($K_d$, $9.52{\times}10^{-8}M$). It dose dependently inhibited LPS-mediated activation of human myeloid cells, mouse macrophage cells and human whole blood as measured by the production of tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$) and nitric oxide, whereas other phospho-lipids including phosphatidylserine and phosphatidylethanolamine had little effect. PE-DTPA also inhibited transcription dependent on $NF-{\kappa}B$ activation when it was added together with LPS, and it rescued LPS-primed mice from septic death. These results suggest that PE-DTPA is a potent antagonist of LPS, and that it acts by competing for binding to CD14.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.8 no.5
• /
• pp.1201-1210
• /
• 2007

The urban streets as a featured and well performing public space for people should be organized in a way that can work as a whole system through network as well as that can provide amenities fur pedestrian. This is a study on Seattle's 'Blue Ring' project for an analysis focused on how its street weaving system organized and what are the design characteristics of the streets. The results are as followings. (1)Pedestrian oriented design, (2)Urban street as a part of open space that can accommodate human activities, (3)Integrated, not isolated with outer/ other open space, (4)Organically networked in a hierarchical manner that can promote pedestrian movement, (5)Utilization of regionally identical design elements. And Smart Growth concept lies in the core of 'Blue Ring' project.

• Proceedings of the Technology Innovation Conference
• /
• 2002.02a
• /
• pp.133-149
• /
• 2002

This study aims to investigate the impact of wide use of digital technology, in particular, the Internet, on innovation process and corporate strategy in electronics industry. The introduction of digital technology has changed innovation process, business model and organizational structure of the electronics companies. With the introduction of digital technology, the entire value chain of electronics industry from procurement, sales, and marketing to R&D and manufacturing has been restructured. E-commerce has been a major agenda for e-business. Recently, collaboration among electronics companies through e-marketplace has emerged as an important issue. A web-based e-commerce standard, so called RosettaNet, has been developed for facilitating e-transactions of electronics firms. The development of digital technology has dramatically increased the processing speed and sophisticated the virtual reality technology. As simulation becomes easier and more effective, the uncertainty and risk involved in R&D has decreased significantly. Another positive impact is closer cooperation between R&D and manufacturing functions. Taking advantage of automated and flexible production technology, has a new type of firm, so called, EMS (Electronics Manufacturing Services) emerged, whose strategic focus is on manufacturing only. The EMS can be seen as a kind of innovative organization, that is, a modular organization for production function. Digital technology has made convergence of computer and communication possible at early years but right now the convergence has been accelerated in extensive areas of communication, broadcasting, information appliances, software, contents, and services. Firms' effort for an innovative product and service has been intensified and the competition for a new standard product and service has become severe in electronics industry. Business activities are always realized in a specific organizational context. Accordingly building up innovation-friendly organization has emerged as a critical concern. Due to the striking decrease of transaction cost, a network type of organization has proliferated, and a business function turns into a modular organization. As a whole, digital technology has pushed electronics firms into developing their own business model, which takes consideration of standardization of business platform and their core competency.

• Journal of KIISE:Information Networking
• /
• v.29 no.2
• /
• pp.156-164
• /
• 2002

IPSec is a protocol which provides data encryption, message authentication and data integrity on public and open network transmission. In IPSec, ESP protocol is used when it needs to provide data encryption, authentication and Integrity In real transmission packets. ESP protocol uses DES-CBC encryption mode when sender encrypts packets and receiver decrypts data through this mode IV is used at that time. This value has many tasks of attack during transmission by attacker because it is transferred clean and opened. If IV value is modified, then decryption of ESP data is impossible and higher level information is changed. In this paper we propose a new algorithm that it encrypts IV values using DES-ECB mode for preventing IV attack and checks integrity of whole ESP data using message authentication function. Therefore, we will protect attacks of IV and data, and guarantee core safe transmission on the public network.