• 한국엔터테인먼트산업학회논문지
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• 제13권8호
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• pp.231-242
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• 2019

영국 태생의 이란인 2세 애나 릴리 아미푸르 감독의 뱀파이어 영화 <밤을 걷는 뱀파이어 소녀 A Girl Walks Home Alone at Night>(2014)는 이란인들이 사는 유령마을(Iranian ghost-town) '배드 시티'를 배경으로 스트라이프 티셔츠를 입고 검은 차도르를 두른 채 스케이트보드를 타는 여성 뱀파이어를 등장시켜 여러 문화의 재조합이 어떻게 문화·정치적으로 흥미로운 해석을 만들어내는지 시도하고 있다. 전통적인 호러 영화에서 흡혈귀 서사의 중심에는 주로 타자로서의 드라큘라-남성이 있었으나 포스트모더니즘 이후의 영화들은 희생자 캐릭터에 머물러 있던 여성을 뱀파이어 주체로 자리를 옮기는 시도를 한다. 본 영화의 주인공 소녀는 보수적인 가부장 사회의 여성-무슬림-뱀파이어로 여성을 향해 폭력을 행사하는 남성을 처단한다. 흑백으로 촬영한 영상은 스토리보다는 이미지를 앞세우며 이란계 배우들이 등장해 페르시아어로 대화한다. 또한, 이란의 저항적인 록음악과 영국 스타일의 테크노 팝이 어우러져 이란의 정치학과 미국-유럽의 팝 컬처를 크로스 오버한다. 본 연구는 뱀파이어 영화의 전통적인 관습을 따르지 않으면서 장르 혼성과 여러 문화적 도상을 내세우며 뱀파이어의 소재의 이야기를 동시대의 문제의식으로 전환하고 이식해내는 데 성공한 <밤을 걷는 뱀파이어 소녀>에 특징적으로 나타난 스타일에 주목해 분석해보고자 한다.

• Asian Pacific Journal of Cancer Prevention
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• 제13권9호
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• pp.4827-4834
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• 2012

Tumor suppressor genes have received much attention for their roles in the development of human malignancies. Gelsolin has been found to be down-regulated in several types of human cancers, including leukemias. It is, however, expressed in macrophages, which are the final differentiation derivatives for the monocytic myeloid lineage, implicating this protein in the differentiation process of such cells. In order to investigate the role of gelsolin in leukaemic cell differentiation, stable clones over-expressing ectopic gelsolin, and a control clone were established from U937 leukaemia cells. Unlike the control cells, both gelsolin-overexpressing clones displayed retarded growth, improved monocytic morphology, increased NADPH and NSE activities, and enhanced surface expression of the ${\beta}$-integrin receptor, CD11b, when compared with the parental U937 cells. Interestingly, RT-PCR and western blot analysis also revealed that gelsolin enhanced p21CIP1 mRNA and protein expression in the overexpressing clones. Moreover, transient transfection with siRNA silencing P21CIP1, but not the control siRNA, resulted in a reduction in monocytic differentiation, accompanied by an increase in proliferation. In conclusion, our work demonstrates that gelsolin, by itself, is capable of inducing monocytic differentiation in U937 leukaemia cells, most probably through p21CIP1 activation.

• The Korean Journal of Pain
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• 제30권4호
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• pp.265-271
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• 2017

Background: Health care services effort to provide alternative cardiac rehabilitation (CR) models to serve patients according to their preferences and needs. So, the present study aimed to assess and compare the effects of hospital-based and hybrid CR programs on chest pain intensity and discomfort in cardiac surgery patients. Methods: In this prospective study, 110 cardiac surgery patients were invited to the CR department of a hospital in the western part of Iran between March and July 2016. Patients were divided into two groups: hospital-based and hybrid CR. The hospital-based program included 26 sessions, and the hybrid program included 10 training sessions and exercise. The Brief Pain Inventory and Pain Discomfort Scale were used as research instrument, and data were analyzed using the paired t-test and ANCOVA. Results: The results indicated that both hospital-based and hybrid CR are effective in reducing the chest pain intensity and discomfort of cardiac surgery patients (P < 0.05). In addition, the comparison of scores before and after treatment using ANCOVA shows that no significant differences were observed between the two programs (P > 0.05). Conclusions: Traditional hospital-based CR delivery is still the first choice for treatment in developing countries. However, hybrid CR is as effective as a hospital-based program in reducing pain components and it includes only 38% of the total cost in comparison to hospital-based delivery. So, we recommend using hybrid CR according with the recommendations of American Heart Association about using CR for the management of angina symptoms.

• Advances in Energy Research
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• 제5권2호
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• pp.107-128
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• 2017

Energy is a major component of almost all economic, production, and service activities, and rapid population growth, urbanization and industrialization have led to ever growing demand for energy. Limited energy resources and increasingly evident environmental effects of fossil fuel consumption has led to a growing awareness about the importance of further use of renewable energy sources in the countries energy portfolio. Renewable hydrogen production is a convenient method for storage of unstable renewable energy sources such as wind and solar energy for use in other place or time. In this study, suitability of 25 cities located in Iran's western region for renewable hydrogen production are evaluated by multi-criteria decision making techniques including TOPSIS, VIKOR, ELECTRE, SAW, Fuzzy TOPSIS, and also hybrid ranking techniques. The choice of suitable location for the centralized renewable hydrogen production is associated with various technical, economic, social, geographic, and political criteria. This paper describes the criteria affecting the hydrogen production potential in the study region. Determined criteria are weighted with Shannon entropy method, and Angstrom model and wind power model are used to estimate respectively the solar and wind energy production potential in each city and each month. Assuming the use of proton exchange membrane electrolyzer for hydrogen production, the renewable hydrogen production potential of each city is then estimated based on the obtained wind and solar energy generation potentials. The rankings obtained with MCDMs show that Kermanshah is the best option for renewable hydrogen production, and evaluation of renewable hydrogen production capacities show that Gilangharb has the highest capacity among the studied cities.

• Geomechanics and Engineering
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• 제16권1호
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• pp.21-34
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• 2018

Discontinuities considerably affect the mechanical and hydraulic properties of rock mass. These properties of the rock mass are influenced by the geometry of the discontinuities to a great extent. This paper aims to render an account of the geometrical parameters of several discontinuity sets related to the surrounding rock mass of Rudbar Lorestan Pumped Storage Power Plant powerhouse cavern making use of the linear and areal (circular and rectangular) sampling methods. Taking into consideration quite a large quantity of scanline and the window samplings used in this research, it was realized that the areal sampling methods are more time consuming and cost-effective than the linear methods. Having corrected the biases of the geometrical properties of the discontinuities, density (areal and volumetric) as well as the linear, areal and volumetric intensity accompanied by the other properties related to four sets of discontinuities were computed. There is an acceptable difference among the mean trace lengths measured using two linear and areal methods for the two joint sets. A 3D discrete fracture network generation code (3DFAM) has been developed to model the fracture network based on the mapped data. The code has been validated on the basis of numerous geometrical characteristics computed by use of the linear, areal sampling methods and volumetric method. Results of the linear sampling method have significant variations. So, the areal and volumetric methods are more efficient than the linear method and they are more appropriate for validation of 3D DFN (Discrete Fracture Network) codes.

• Asian Pacific Journal of Cancer Prevention
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• 제14권3호
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• pp.1813-1817
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• 2013

Background: Multiple etiologic factors are suspected to cause gastric cancer, the most important of which is infection with virulent types of Helicobacter pylori. Materials and Methods: We have compared 102 gastric cancer patients with 122 non-ulcer, non-cancer dyspeptic patients. Gastric specimens were evaluated for H. pylori infection by tissue-based detection methods. Patient sera underwent antigen-specific ELISA and western blotting using a Helicoblot 2.1 kit and antibody responses to various H. pylori antigens were assessed. Results: The absolute majority (97-100%) of both groups were H. pylori seropositive. Multivariate regression analysis demonstrated serum antibodies to the low molecular weight 35kDa protein to be protective and reduce the risk of gastric cancer by 60% (OR:0.4; 95%CI:0.1-0.9). Conversely, seroreactivity to the 89kDa (VacA) protein was significantly higher in gastric cancer patients (OR:2.7; 95%CI:1.0-7.1). There was a highly significant association (p<0.001) between seroreactivity to the 116kDa (CagA) and 89kDa (VacA) proteins, and double positive subjects were found at nearly five fold (OR:4.9; 95%CI:1.0-24.4) enhanced risk of gastric cancer as compared to double negative subjects. Conclusions: Seroreactivity to H. pylori low (35kDa) and high (116kDa/89kDa) molecular weight antigens were respectively revealed as protective and risk indicators for gastric cancer.

• Advances in Traditional Medicine
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• 제10권4호
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• pp.304-309
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• 2010

Scutellaria pinnatifida A. Hamilt. (Lamiaceae) is an endemic Turkish herb. This plant is also endemic to Iran, and grows abundantly in other central and western Asian countries. Several species of the Scutellaria are known for their traditional uses in the treatment of hypertension, arteriosclerosis, inflammatory diseases, hepatitis, allergy, cancer and diarrhoea. Free-radical-scavenging property, antibacterial activity and brine shrimp toxicity of the n-hexane, dichloromethane (DCM) and methanol (MeOH) extracts of S. pinnatifida were assessed using the 2,2-diphenyl-1-picryl-hydrazyl (DPPH) assay, the resazurin microtitre plate based assay, and the brine shrimp lethality assay, respectively. The DCM and MeOH extracts exhibited free-radical-scavenging property, with the $RC_{50}$ values of 0.362 and 0.127 mg/ml, respectively. Among the solid-phase extraction fractions of the MeOH extract, the 50% aqueous-MeOH fraction showed the highest level of free-radicalscavenging activity ($RC_{50}$ = 0.039 mg/ml). While the DCM extract showed low level of antibacterial activity against Bacillus subtilis and ampicillin-resistant Escherichia coli, the MeOH extract was active against B. cereus, B. subtilis, E. coli and ampicillin-resistant E. coli. However, the minimum inhibitory concentrations (MIC) of the MeOH extract against these bacterial strains were >10 mg/ml. None of the extracts showed any significant toxicity towards brine shrimps ($LD_{50}$ = > 1.00 mg/ml).

• Asian Pacific Journal of Cancer Prevention
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• 제16권14호
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• pp.6155-6158
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• 2015

Background: The human leukocyte antigen-G (HLA-G) gene is highly expressed in cancer pathologies and is one strategy used by tumor cells to escape immune surveillance. A 14-bp insertion/deletion (InDel) polymorphism of the HLA-G gene has been suggested to be associated with HLA-G mRNA stability and the expression of HLA-G. The aim of present study was to assess any genetic association between this polymorphism and breast cancer among Iranian-Azeri women. Materials and Methods: In this study 227 women affected with breast cancer, in addition to 255 age-sex and ethnically matched healthy individuals as the control group, participated. Genotyping was performed using polymerase chain reaction and electrophoresis assays. The data were compiled according to the genotype and allele frequencies, compared using the Chi-square test. Statistical significance was set at P<0.05. Results: In this case-control study, no significant difference was found between the case and control groups at allelic and genotype levels, although there is a slightly higher allele frequency of HLA-G 14bp deletion in breast cancer affected group. However,when the stage I subgroup was compared with stage II plus stage III subgroup of affected breast cancer, a significant difference was seen with the 14 bp deletion allele frequency. The stage II-III subgroup patients had higher frequency of deletion allele (57.4% vs 45.8%) than stage I cases (${\chi}^2=4.16$, p-value=0.041). Conclusions: Our data support a possible action of HLA-G 14bp InDel polymorphism as a potential genetic risk factor for progression of breast cancer. This finding highlights the necessity of future studies of this gene to establish the exact role of HLA-G in progression steps of breast cancer.

• Smart Structures and Systems
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• 제26권3호
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• pp.277-290
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• 2020

Disasters, including earthquakes and landslides, have enormous economic and social losses besides their impact on environmental disruption. Iran, and particularly its Western part, is known as an earthquake susceptible area due to numerous strong ground motions. Studying ecological changes due to climate change can improve the public and expert sector's awareness and response to future disastrous events. Synthetic Aperture Radar (SAR) data and Interferometric Synthetic Aperture Radar (InSAR) technologies are appropriate tools for modeling and surface deformation modeling. This paper proposes an efficient approach to detect ground deformation changes using Sentinel-1A. The focal point of this research is to map the ground surface deformation modeling is presented using InSAR technology over Sarpol-e Zahab on 25^th November 2018 as a study case. For surface deformation modeling and detection of the ground movement due to earthquake SARPROZ in MATLAB programming language is used and discussed. Results show that there is a general ground movement due to the Sarpol-e Zahab earthquake between -7 millimeter to +18 millimeter in the study area. This research verified previous researches on the advanced image analysis techniques employed for mapping ground movement, where InSAR provides a reliable tool for assisting engineers and the decision-maker in choosing proper policies in a time of disasters. Based on the result, 574 out of 682 damaged buildings and infrastructures due to the 2017 Sarpol-e Zahab earthquake have moved from -2 to +17 mm due to the 2018 earthquake with a magnitude of 6.3 Richter. Results show that mountainous areas have suffered land subsidence, where urban areas had land uplift.

• Geomechanics and Engineering
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• 제34권3호
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• pp.267-284
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• 2023

Landslides are one of the most dangerous phenomena and natural disasters. Landslides cause many human and financial losses in most parts of the world, especially in mountainous areas. Due to the climatic conditions and topography, people in the northern and western regions of Iran live with the risk of landslides. One of the measures that can effectively reduce the possible risks of landslides and their crisis management is to identify potential areas prone to landslides through multi-criteria modeling approach. This research aims to model landslide potential area in the Oshvand watershed using a support vector machine algorithm. For this purpose, evidence maps of seven effective factors in the occurrence of landslides namely slope, slope direction, height, distance from the fault, the density of waterways, rainfall, and geology, were prepared. The maps were generated and weighted using the continuous fuzzification method and logistic functions, resulting values in zero and one range as weights. The weighted maps were then combined using the support vector machine algorithm. For the training and testing of the machine, 81 slippery ground points and 81 non-sliding points were used. Modeling procedure was done using four linear, polynomial, Gaussian, and sigmoid kernels. The efficiency of each model was compared using the area under the receiver operating characteristic curve; the root means square error, and the correlation coefficient . Finally, the landslide potential model that was obtained using Gaussian's kernel was selected as the best one for susceptibility of landslides in the Oshvand watershed.