• Title/Summary/Keyword: West End

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Effects of Scutellariae Radix on Neuronal Apoptosis of Spinal Cord Contusion Injury in Rats (황금(黃芩)이 척수압박손상 흰쥐의 척수신경세포 자연사에 미치는 영향)

  • Bahn, Hyo-Jung;Jo, Jong-Jin;Kim, Bum-Hoi;Park, Seong-Ha;Shin, Jung-Won;Kim, Seong-Joon;Sohn, Nak-Won
    • Journal of Korean Medicine Rehabilitation
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    • v.21 no.4
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    • pp.13-22
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    • 2011
  • Objectives : This Study was performed to evaluate the effects of Scutellariae Radix(SR) water-extract on the tissue and neuronal apoptosis of the spinal cord injury(SCI). Methods: SCI was induced by mechanical contusion following laminectomy of 10th thoracic vertebra in Sprague-Dawley rats. SR was orally given once a day for 7 days after SCI. Neuronal apoptosis was examined with terminal deoxynucleotidyl transferase-mediated dUTPnick-end labeling(TUNEL) assay. Bax (Bcl-2-asociated X protein), Bcl-2(B-cell blastoma 2), c-Fos(FBJ osteosarcoma oncogene) expressions were examined using immuno-histochemistry. Individual TUNEL and immuno-labeled cells expressing Bax, Bcl-2 and c-Fos were counted on the same level in peri-damaged region and in ventral horn. Results: 1. SR significantly reduced number of TUNEL labeled apoptotic cells induced by the spinal cord contusion injury. 2. SR significantly reduced Bax positive cells expression on the motor neuron in the ventral horn induced by the spinal cord contusion injury. 3. SR strengthened Bcl-2 expression on the motor neuron in the ventral horn induced by the spinal cord contusion injury. 4. SR reduced c-Fos expression on the motor neuron in the ventral horn induced by the spinal cord contusion injury. Conclusions : These results suggest that SR plays an inhibitory role against neuronal apoptosis and has significant effects for locomotor disfunction induced by SCI.

Experimental Analysis of Kinematic Network-Based GPS Positioning Technique for River Bathymetric Survey

  • Lee, Hungkyu;Lee, Jae-One;Kim, Hyundo
    • Journal of Positioning, Navigation, and Timing
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    • v.5 no.4
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    • pp.221-233
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    • 2016
  • This paper deals with performance assessment of the kinematic network-based GPS positioning technique with a view to using it for ellipsoidally referenced bathymetric surveys. To this end, two field trials were carried out on a land vehicle and a surveying vessel. Single-frequency GPS data acquired from these tests were processed by an in-house software which equips the network modeling algorithm with instantaneous ambiguity resolution procedure. The results reveals that ambiguity success rate based on the network model is mostly higher than 99.0%, which is superior to that of the single-baseline model. In addition, achievable accuracy of the technique was accessed at ${\pm}1.6cm$ and 2.7 cm with 95% confidence level in horizontal and vertical component respectively. From bathymetric survey at the West Nakdong River in Busan, Korea, 3-D coordinates of 2,011 points on its bed were computed by using GPS-derived coordinates, attitude, measured depth and geoid undulation. Note that their vertical coordinates are aligned to the geoid, the so-called orthometric height which is widely adopted in river engineering. Bathymetry was constructed by interpolating the coordinate set, and some discussion on its benefit was given at the end.

THE DEVELOPMENT OF THE SILK ROAD: THE POSTAL RELAY ROUTE OF MONGOL AND GORYEO

  • KIM, TSCHUNG-SUN
    • Acta Via Serica
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    • v.1 no.1
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    • pp.105-117
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    • 2016
  • The Silk Road named by Ferdinand von Richthofen was not designated as a specific route. A lot of East-West trade routes had already existed across the continent and the geographical scope and definition of the Silk Road is still expanding. In particular, the claim that the Eastern end of the Silk Road reaches Gyeongju is an example of this expansion. Burial treasures from tombs on the Korean Peninsula have already been identified as products from the Sassanian Dynasty of Persia, and various archaeological and epical evidences support this finding. However, the specific route where these exchanges were made, around the 6th-8th centuries, has yet to be identified. Maritime as well as inland routes can easily be hypothesized. The Silk Road was largely activated by the Yam postal system with the expansion of the Mongol Empire. It not only served as an effective pathway for the Yuan to rule over the Goryeo, but also connected the Eastern end of the Silk Road to Gyeongju. This can explain the situation since the 13th century. Therefore, this paper claims that the Yeokcham system had been operating on the Korean Peninsula since the Unified Silla Kingdom, the previous period of Goryeo, or perhaps even before then. The Yeokcham should thus be regarded as a prototype of the Mongolian Yam, and the Korean peninsula should be recognized as another route which contributed specifically to the development of the Silk Road, not just as a user or a beneficiary.

Trade Routes, Trading Centers and the Emergence of the Domestic Market in Azerbaijan in the Period of Arab-Khazar Domination on the Silk Road

  • ASADOV, FARDA
    • Acta Via Serica
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    • v.4 no.1
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    • pp.1-24
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    • 2019
  • Bloody wars between Arab Muslims and Khazar Turks in the Caucasus continued for a more than a hundred years from the mid $7^{th}$ century to the end of the $8^{th}$ century CE. The Khazar state survived but had to withdraw from Caucasian Albania, the present territory of the Republic of Azerbaijan. However, the Khazars managed to expand their political control over the trade routes north-east and north-west of the Caucasian ridge. A trade partnership was established between former rival powers in the region that allows us to call the period after the end of the Arab-Khazar wars up to the time of the collapse of the Khazar state in the middle of the 10th century an era of Arab-Khazar partnership and domination of the Silk Road. This article highlights the impact made by geopolitical shifts in the regions of the time upon international trade tracks and particularly on the development of trade facilities, infrastructure, and local production in Azerbaijan, which became a major transit country of goods from the north to markets in the Muslim Near East.

Environmental and Ecological Characteristics of Ilex crenata var. microphylla Max. Subpopulations Habitats in the East-West Slopes in Mt. Halla National Park (한라산 동.서사면 좀꽝꽝나무 아개체군 자생지의 환경 및 생태적 특성)

  • Lee, Dong-Gon;Kim, Yong-Shik;Shin, Hyun-Tak
    • Korean Journal of Environment and Ecology
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    • v.25 no.4
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    • pp.562-572
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    • 2011
  • This study is to examine the environmental characteristics of subpopulations of Ilex crenata var. microphyllla Max. distributed in the east-west slopes of Mt. Halla National Park based on analyzing the factors of environment, vegetation and soil. The result of the TWINSAPN analysis conducted on 56 study plots between the altitudes of 500 m and 1600 m of east-west slopes of Mt. Halla National Park can be divided into five communities-Prunus maximowiczii Rupr., Manshurian fullmoon Maple, Carpinus tschonoskii Max., Daphniphyllum macropodum Miq., Quercus serrata Thunb. ex Murray and Pinus thunbergil Parl. Among these communities, the plot with high importance percentage of the subpopulation of Ilex crenata var. microphyllla Max., is the Carpinus tschonoskii Max.-Daphniphyllum macropodum Miq. included in the altitude of 600m~1200m radius. The dominant species of the upper shrub layer was Carpinus tschonoskii Max.(I.P.: 29.82%) while the dominant species of the canopy layer was Daphniphyllum macropodum Miq.(I.P.: 26.76%). For the understory layer the dominant species was Ilex crenata var. microphyllla Max.. Species diversity index was on the low end with 0.7424, indicating the stably formed climax community of Carpinus tschonoskii Max.. The analysis of soil properties showed high concentrations of organic matters, available phosphate and Ca, Mg, the high importance percentage of the of Ilex crenata var. microphyllla Max. is found in altitude of 600m~800m on the eastern slope and the altitude of 800m~1,000m radius on the west slope. This region is included in the southern part of the cold/hot forest zone, its high importance percentage of Carpinus tschonoskii Max. and low in the species diversity index of 0.7424, and has formed stable climax community of Carpinus tschonoskii Max. in Mt. Halla.

The Transition of the Historical Landscape in Hangzhou, China - Focus on the Landscape of West Lake - (중국 항주(杭州)의 역사경관 변천과정 - 서호(西湖) 경관을 중심으로 -)

  • Pan, Xiang;Xu, Huan;Kang, Tai-Ho
    • Journal of the Korean Institute of Traditional Landscape Architecture
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    • v.30 no.4
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    • pp.32-43
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    • 2012
  • Hangzhou, in China, is a city that has a history as long as 2,300 years and is renowned due to its natural scenery of a beautiful lake surrounded by gentle green hills. This world wide famous scenery, known as West Lake(西湖), in 2011, was included in the World Heritage Landscape List. Though this place experienced enormous development and changes during thousands of years, historic sceneries did not disappear with the passage of time. In contrary, they are refined and increased attributing to protection efforts from past dynasties. Therefore, research in landscape transition is significant for building livable environment and preserving historical landscape. This paper mainly focuses on history transition of city Hangzhou. First of all, its urban construction and guiding ideology is analyzed. Then, deep meticulous research is carried out on development and preservation achievements for dynasty Tang, Song, Yuan, Ming and Qing. In the end, from a historical point of view, this paper will provide a new perspective which would contribute to sustainable preservation of historical landscape. From the Song Dynasty to the Qing Dynasty, the West Lake through several times of the rectification and construction, the present landscape was completed during thousand years several times through the construction.

Effect of nutrition education and traditional game-based physical activity interventions, on lipid profile improvement in overweight and obese children in West Java Indonesia

  • Yulia, Cica;Khomsan, Ali;Sukandar, Dadang;Riyadi, Hadi
    • Nutrition Research and Practice
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    • v.15 no.4
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    • pp.479-491
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    • 2021
  • BACKGROUND/OBJECTIVES: One ongoing effort to curtail dyslipidemia in school children is through lifestyle intervention. This study analyzes outcomes of the intervention of nutrition education and Javanese traditional game-based physical activity, on lipid profiles of overweight and obese children. SUBJECTS/METHODS: The experimental study consisted of three steps: data collection (October to December 2016), intervention processes (January to March 2017), and final report preparation (April to May 2017). This was a split-plot block study, enrolling a total of 72 subjects. Traditional game intervention (12 meetings) and nutrition education (9 meetings) was carried out within 3 months with material related to obesity. RESULTS: Our results showed no decrease in the levels of total cholesterol in the group receiving nutrition education (rise by 1.56 mg/dL), but when compared to subjects without intervention, total cholesterol levels experienced was increased. The group which did not receive physical activity showed increase in the total cholesterol, whereas the traditional game intervention group showed a decrease of 0.05 mg/dL total cholesterol at the end of the intervention. Nutrition education and physical activity interventions did not influence any reduction in the low-density lipoprotein cholesterol (LDL-C) levels, but rather showed a tendency to increase at the end of the intervention. However, the increase in LDL-c levels in the traditional game group was lower than in other intervention groups. Duncan's test indicated that the effect of nutrition education and physical activity interventions did not differ from the cut-off values of LDL-C and high-density lipoprotein cholesterol. CONCLUSIONS: Total cholesterol and triglyceride levels in the traditional game group tended to decrease at the end of the intervention, but the results did not differ much from other intervention groups. We deduce that nutrition education and traditional game-based physical activity interventions are not capable of improving blood lipid profiles in overweight and obese children within 3 months. It is necessary to increase the time of physical activity intervention to maintain the lipid profile in another study.

THE EFFECT OF SEVERAL ROOT-END FILLING MATERIALS ON MG63 OSTEOBLAST-LIKE CELLS (수종의 치근단역충전 재료가 MG63 osteoblast-like cells에 미치는 영향)

  • Lee, Jeong-Ho;Shon, Won-Jun;Lee, Woo-Cheol;Baek, Seung-Ho
    • Restorative Dentistry and Endodontics
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    • v.35 no.3
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    • pp.222-228
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    • 2010
  • The purpose of this study was to compare mineral trioxide aggregate (MTA; Dentsply, Tulsa Dental, Tulsa, OK, USA), which is widely used as root-end filling material, with DiaRoot BioAggregate (DB; Innovative BioCaramix Inc, Vancouver, BC, Canada), newly developed product, by using MG63 osteoblast-like cells. MTA, DB, and Intermediate Restorative Material (IRM; Dentsply Caulk, Milford, DE, USA) were used for root-end filling material while tissue culture plastic was used for control group. Each material was mixed and, the mixtures were left to set for 24 hours. MG63 cells were seeded to each group and then they were cultured for attachment for 4 hours. Following the attachment of cells to the root-end filling material, early cellular response was observed. After another 12 hours'culture, the level of attachment between cells and material was observed and in order to identify the effect of each material to bone formation, transforming growth factor beta1 ($TGF{\beta}1$) and osteocalin (OC) were estimated by using enzyme-linked immunosorbent assay (ELISA), and the amount of alkaline phosphatase (ALP) was also measured. The data were analyzed using one-way ANOVA. As a result, only at OC and the number of cells which were attached to materials, there was no statistical difference between MTA and DB. At other items, there was statistically significant difference in all groups. Although DB has not shown exactly the same cellular response like that of MTA, the number of attached cells shows that biocompatibility of the material and OC indicates bone formation rate. Therefore, if DB is used for root end filling material, it is expected to lead to similar results to MTA.

A Study on the Characteristics of the Heavy Rainfall Events in Honam District along the Border of mT Airmass

  • Yang, Se-Hwan;Ryu, Chan-Su
    • Journal of Integrative Natural Science
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    • v.5 no.4
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    • pp.220-228
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    • 2012
  • District of Korea affected by westerly wind and heavy rainfall is predominantly distributed in the west and south of Honam district. So, this study is becoming a necessity. In this study, it is investigated that the characteristics of heavy rainfall occurred frequently in Honam district along the border of mT airmass after the end of rainy season due to atmospheric instability, lower (850 hPa) convergence and topographic effect. Our results show that heavy rainfall occurred in Honam district along the border of mT airmass results from the appropriate mechanism of the unstable vertical structure and moisture flux in the expansion and contraction of the border of mT airmass. All things considered, the improvement of the predictability of heavy rainfall occurred in Honam district along the border of mT airmass could be possible by the generalization of the results of this study.

Evaluation of methods for estimating the pulse reflection site with cardiovascular simulator (심혈관계 시뮬레이터를 이용한 맥파 반사지점 추정방법들의 비교)

  • Lee, Ju-Yeon;Shin, Sang-Hoon
    • The Journal of the Society of Korean Medicine Diagnostics
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    • v.19 no.1
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    • pp.47-54
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    • 2015
  • Objective Wave reflection is an important factor that determines the shape of the pulse wave. The purpose of this study is to compare the conventional method used for estimating the reflection site of pulse with a cardiovascular simulator. Methods: In this study, cardiovascular simulator with one elastic tube was used. The pressure and flow was measured simultaneously at three different points. The measured data were used to the conventional methods to estimate the pulse wave reflection site. The results were compared with the known length which were the distances from the measured points to the end of tube. Results & Conclusions: There is a significant error with the time domain method. While, the reflection site with the frequency domain method was similar to the actual reflection site.