• 제목/요약/키워드: West End

검색결과 197건 처리시간 0.033초

황금(黃芩)이 척수압박손상 흰쥐의 척수신경세포 자연사에 미치는 영향 (Effects of Scutellariae Radix on Neuronal Apoptosis of Spinal Cord Contusion Injury in Rats)

  • 반효정;조종진;김범회;박성하;신정원;김성준;손낙원
    • 한방재활의학과학회지
    • /
    • 제21권4호
    • /
    • pp.13-22
    • /
    • 2011
  • Objectives : This Study was performed to evaluate the effects of Scutellariae Radix(SR) water-extract on the tissue and neuronal apoptosis of the spinal cord injury(SCI). Methods: SCI was induced by mechanical contusion following laminectomy of 10th thoracic vertebra in Sprague-Dawley rats. SR was orally given once a day for 7 days after SCI. Neuronal apoptosis was examined with terminal deoxynucleotidyl transferase-mediated dUTPnick-end labeling(TUNEL) assay. Bax (Bcl-2-asociated X protein), Bcl-2(B-cell blastoma 2), c-Fos(FBJ osteosarcoma oncogene) expressions were examined using immuno-histochemistry. Individual TUNEL and immuno-labeled cells expressing Bax, Bcl-2 and c-Fos were counted on the same level in peri-damaged region and in ventral horn. Results: 1. SR significantly reduced number of TUNEL labeled apoptotic cells induced by the spinal cord contusion injury. 2. SR significantly reduced Bax positive cells expression on the motor neuron in the ventral horn induced by the spinal cord contusion injury. 3. SR strengthened Bcl-2 expression on the motor neuron in the ventral horn induced by the spinal cord contusion injury. 4. SR reduced c-Fos expression on the motor neuron in the ventral horn induced by the spinal cord contusion injury. Conclusions : These results suggest that SR plays an inhibitory role against neuronal apoptosis and has significant effects for locomotor disfunction induced by SCI.

Experimental Analysis of Kinematic Network-Based GPS Positioning Technique for River Bathymetric Survey

  • Lee, Hungkyu;Lee, Jae-One;Kim, Hyundo
    • Journal of Positioning, Navigation, and Timing
    • /
    • 제5권4호
    • /
    • pp.221-233
    • /
    • 2016
  • This paper deals with performance assessment of the kinematic network-based GPS positioning technique with a view to using it for ellipsoidally referenced bathymetric surveys. To this end, two field trials were carried out on a land vehicle and a surveying vessel. Single-frequency GPS data acquired from these tests were processed by an in-house software which equips the network modeling algorithm with instantaneous ambiguity resolution procedure. The results reveals that ambiguity success rate based on the network model is mostly higher than 99.0%, which is superior to that of the single-baseline model. In addition, achievable accuracy of the technique was accessed at ${\pm}1.6cm$ and 2.7 cm with 95% confidence level in horizontal and vertical component respectively. From bathymetric survey at the West Nakdong River in Busan, Korea, 3-D coordinates of 2,011 points on its bed were computed by using GPS-derived coordinates, attitude, measured depth and geoid undulation. Note that their vertical coordinates are aligned to the geoid, the so-called orthometric height which is widely adopted in river engineering. Bathymetry was constructed by interpolating the coordinate set, and some discussion on its benefit was given at the end.

THE DEVELOPMENT OF THE SILK ROAD: THE POSTAL RELAY ROUTE OF MONGOL AND GORYEO

  • KIM, TSCHUNG-SUN
    • Acta Via Serica
    • /
    • 제1권1호
    • /
    • pp.105-117
    • /
    • 2016
  • The Silk Road named by Ferdinand von Richthofen was not designated as a specific route. A lot of East-West trade routes had already existed across the continent and the geographical scope and definition of the Silk Road is still expanding. In particular, the claim that the Eastern end of the Silk Road reaches Gyeongju is an example of this expansion. Burial treasures from tombs on the Korean Peninsula have already been identified as products from the Sassanian Dynasty of Persia, and various archaeological and epical evidences support this finding. However, the specific route where these exchanges were made, around the 6th-8th centuries, has yet to be identified. Maritime as well as inland routes can easily be hypothesized. The Silk Road was largely activated by the Yam postal system with the expansion of the Mongol Empire. It not only served as an effective pathway for the Yuan to rule over the Goryeo, but also connected the Eastern end of the Silk Road to Gyeongju. This can explain the situation since the 13th century. Therefore, this paper claims that the Yeokcham system had been operating on the Korean Peninsula since the Unified Silla Kingdom, the previous period of Goryeo, or perhaps even before then. The Yeokcham should thus be regarded as a prototype of the Mongolian Yam, and the Korean peninsula should be recognized as another route which contributed specifically to the development of the Silk Road, not just as a user or a beneficiary.

Trade Routes, Trading Centers and the Emergence of the Domestic Market in Azerbaijan in the Period of Arab-Khazar Domination on the Silk Road

  • ASADOV, FARDA
    • Acta Via Serica
    • /
    • 제4권1호
    • /
    • pp.1-24
    • /
    • 2019
  • Bloody wars between Arab Muslims and Khazar Turks in the Caucasus continued for a more than a hundred years from the mid $7^{th}$ century to the end of the $8^{th}$ century CE. The Khazar state survived but had to withdraw from Caucasian Albania, the present territory of the Republic of Azerbaijan. However, the Khazars managed to expand their political control over the trade routes north-east and north-west of the Caucasian ridge. A trade partnership was established between former rival powers in the region that allows us to call the period after the end of the Arab-Khazar wars up to the time of the collapse of the Khazar state in the middle of the 10th century an era of Arab-Khazar partnership and domination of the Silk Road. This article highlights the impact made by geopolitical shifts in the regions of the time upon international trade tracks and particularly on the development of trade facilities, infrastructure, and local production in Azerbaijan, which became a major transit country of goods from the north to markets in the Muslim Near East.

한라산 동.서사면 좀꽝꽝나무 아개체군 자생지의 환경 및 생태적 특성 (Environmental and Ecological Characteristics of Ilex crenata var. microphylla Max. Subpopulations Habitats in the East-West Slopes in Mt. Halla National Park)

  • 이동곤;김용식;신현탁
    • 한국환경생태학회지
    • /
    • 제25권4호
    • /
    • pp.562-572
    • /
    • 2011
  • 본 연구는 한라산국립공원의 동 서사면에 자생하는 좀꽝꽝나무 아개체군의 환경특성을 파악하기 위하여 환경요인, 식생 및 토양분석을 실시하였다. 한라산국립공원의 동 서사면 해발고 500m~1600m 내에 설정한 56개 조사지를 대상으로 TWINSPAN 분석결과 주목-산개벚지나무군집, 당단풍나무군집, 개서어나무-굴거리나무군집, 졸참나무군집, 곰솔군집 등 5개의 유형으로 구분되었다. 이 중 좀꽝꽝나무 아개체군의 우점치가 높은 군집은 개서어나무-굴거리나 무군집으로 해발고 600m~1200m 지점에 포함되며, 교목상층의 우점종은 개서어나무(I.P.: 29.82%)이고 아교목층의 우점종은 굴거리나무(I.P.: 26.76%), 관목층은 좀꽝꽝나무(I.P.: 33.08%)이었다. 이곳의 토양은 유기물함량, 유효인산 및 Ca, Mg의 양료가 많은 곳이다. 좀꽝꽝나무 아개체군의 우점치가 높은 곳은 동쪽사면 해발고 600m~800m, 서쪽사면 해발고 800m~1,000m 부근으로 이곳은 냉온삼림대 남부에 해당되는 곳으로 개서어나무의 우점치가 높고 종다양도지수도 0.7427로 낮은 편으로 개서어나무의 극상림을 형성한 안정된 상태로 보인다.

중국 항주(杭州)의 역사경관 변천과정 - 서호(西湖) 경관을 중심으로 - (The Transition of the Historical Landscape in Hangzhou, China - Focus on the Landscape of West Lake -)

  • 반상;서환;강태호
    • 한국전통조경학회지
    • /
    • 제30권4호
    • /
    • pp.32-43
    • /
    • 2012
  • 항주는 중국에서 2,300년의 역사를 지니고 있으며, 자연풍광이 아름답기로 유명한 역사문화도시이다. 특히 서호는 세계적으로 유명한 경치 좋은 호수로서, 2011년에 유네스코 세계문화경관유산으로 등재되었다. 서호는 변천과정을 거치면서도 역사경관은 사라지지 않고, 각 시기별 지속적인 보호와 관리로 현재까지 최적화를 유지할 수 있었다. 따라서 쾌적한 주거환경을 개발하면서 지속가능한 역사경관의 보존을 위해 서호 경관의 변천과정에 대한 연구는 매우 중요하다. 이 연구에서는 항주 서호 경관의 변천과정을 중심으로 먼저 고대 항주의 도성구조와 사상적 배경을 사료와 문헌을 통해 서호 경관의 당, 송, 원, 명, 청 각 시기의 특징과 변천과정 및 역사적 경험을 분석하였다. 연구결과, 항주는 도성계획에 있어 역(易)과 풍수사상 및 "관자(管子)" 사상에서 영향을 받아 입지선정과 주변의 자연환경과의 고려를 중요시하였다. 따라서 항주 서호 경관의 특징은 산수풍경을 그림처럼 표현하고 지형과 주변 환경에 조성되었다. 서호는 송대 이후, 청대까지의 역대 조정은 천 년 동안 지속적으로 여러 번의 정비와 건설을 통해, 현재의 경관이 완성되었다.

Effect of nutrition education and traditional game-based physical activity interventions, on lipid profile improvement in overweight and obese children in West Java Indonesia

  • Yulia, Cica;Khomsan, Ali;Sukandar, Dadang;Riyadi, Hadi
    • Nutrition Research and Practice
    • /
    • 제15권4호
    • /
    • pp.479-491
    • /
    • 2021
  • BACKGROUND/OBJECTIVES: One ongoing effort to curtail dyslipidemia in school children is through lifestyle intervention. This study analyzes outcomes of the intervention of nutrition education and Javanese traditional game-based physical activity, on lipid profiles of overweight and obese children. SUBJECTS/METHODS: The experimental study consisted of three steps: data collection (October to December 2016), intervention processes (January to March 2017), and final report preparation (April to May 2017). This was a split-plot block study, enrolling a total of 72 subjects. Traditional game intervention (12 meetings) and nutrition education (9 meetings) was carried out within 3 months with material related to obesity. RESULTS: Our results showed no decrease in the levels of total cholesterol in the group receiving nutrition education (rise by 1.56 mg/dL), but when compared to subjects without intervention, total cholesterol levels experienced was increased. The group which did not receive physical activity showed increase in the total cholesterol, whereas the traditional game intervention group showed a decrease of 0.05 mg/dL total cholesterol at the end of the intervention. Nutrition education and physical activity interventions did not influence any reduction in the low-density lipoprotein cholesterol (LDL-C) levels, but rather showed a tendency to increase at the end of the intervention. However, the increase in LDL-c levels in the traditional game group was lower than in other intervention groups. Duncan's test indicated that the effect of nutrition education and physical activity interventions did not differ from the cut-off values of LDL-C and high-density lipoprotein cholesterol. CONCLUSIONS: Total cholesterol and triglyceride levels in the traditional game group tended to decrease at the end of the intervention, but the results did not differ much from other intervention groups. We deduce that nutrition education and traditional game-based physical activity interventions are not capable of improving blood lipid profiles in overweight and obese children within 3 months. It is necessary to increase the time of physical activity intervention to maintain the lipid profile in another study.

수종의 치근단역충전 재료가 MG63 osteoblast-like cells에 미치는 영향 (THE EFFECT OF SEVERAL ROOT-END FILLING MATERIALS ON MG63 OSTEOBLAST-LIKE CELLS)

  • 이정호;손원준;이원철;백성호
    • Restorative Dentistry and Endodontics
    • /
    • 제35권3호
    • /
    • pp.222-228
    • /
    • 2010
  • 본 연구의 목적은 현재 치근단 역충전재로 널리 사용되고 있는 MTA와 새롭게 개발된 제품인 DB를 MG63 세포를 사용하여 비교하는 것이다. 치근단 역충전재료로는 MTA, DB, IRM을 사용하였고 대조군으로는 tissue culture plastic을 사용하였다. 각 재료를 혼합하고 혼합물의 경화가 일어나도록 24시간 동안 놓아두었다. MG63 세포를 각 군에 뿌려준 후 세포가 재료에 부착될 수 있도록 4시간 배양하였다. 치근단 역충전재를 세포에 접촉시킨 후 세포수준의 초기 반응을 관찰하였다. 12시간 더 배양한 후 세포가 각 재료에 붙어 있는 정도를 관찰하고, 각 재료가 골형성에 미치는 영향을 알아보기 위해 ELISA를 이용하여 $TGF{\beta}1$, OC를 측정하였고 ALP의 양도 측정하였다. 결과는 일원배치분산분석법으로 통계처리하였다. 그 결과, 재료에 부착이 일어난 세포의 수 항목과 OC 항목에서만 MTA와 DB간에 통계적으로 차이가 없었다. 다른 항목들에서는 모든 군 간에 통계적으로 유의한 차이가 있었다. DB가 MTA와 완전히 같은 세포반응을 보이지는 않았지만 부착이 일어난 세포의 수는 재료의 생체적합성을 나타내며 OC는 골형성 정도를 나타내므로 DB가 역충전 재료로 사용된다면 MTA와 유사한 결과를 보일 것으로 예측된다.

A Study on the Characteristics of the Heavy Rainfall Events in Honam District along the Border of mT Airmass

  • Yang, Se-Hwan;Ryu, Chan-Su
    • 통합자연과학논문집
    • /
    • 제5권4호
    • /
    • pp.220-228
    • /
    • 2012
  • District of Korea affected by westerly wind and heavy rainfall is predominantly distributed in the west and south of Honam district. So, this study is becoming a necessity. In this study, it is investigated that the characteristics of heavy rainfall occurred frequently in Honam district along the border of mT airmass after the end of rainy season due to atmospheric instability, lower (850 hPa) convergence and topographic effect. Our results show that heavy rainfall occurred in Honam district along the border of mT airmass results from the appropriate mechanism of the unstable vertical structure and moisture flux in the expansion and contraction of the border of mT airmass. All things considered, the improvement of the predictability of heavy rainfall occurred in Honam district along the border of mT airmass could be possible by the generalization of the results of this study.

심혈관계 시뮬레이터를 이용한 맥파 반사지점 추정방법들의 비교 (Evaluation of methods for estimating the pulse reflection site with cardiovascular simulator)

  • 이주연;신상훈
    • 대한한의진단학회지
    • /
    • 제19권1호
    • /
    • pp.47-54
    • /
    • 2015
  • Objective Wave reflection is an important factor that determines the shape of the pulse wave. The purpose of this study is to compare the conventional method used for estimating the reflection site of pulse with a cardiovascular simulator. Methods: In this study, cardiovascular simulator with one elastic tube was used. The pressure and flow was measured simultaneously at three different points. The measured data were used to the conventional methods to estimate the pulse wave reflection site. The results were compared with the known length which were the distances from the measured points to the end of tube. Results & Conclusions: There is a significant error with the time domain method. While, the reflection site with the frequency domain method was similar to the actual reflection site.