Objective: In the present study, we investigated the protective effects of low-intensity treadmill training in doxorubicin-induced cardiotoxicity rat models. Design: Randomized controlled trial. Methods: In this study, we randomly divided them into four groups. The normal group included non-cardiotoxicity normal control (n=10), the control group included non-treadmill training after doxorubicin-induced cardiotoxicity (n=10), the experimental group I included low-intensity treadmill training (3 m/min) after doxorubicin-induced cardiotoxicity (n=10), and the experimental group II included low-intensity treadmill training (8 m/min) after doxorubicin-induced cardiotoxicity (n=10). Rats in the treadmill training group underwent treadmill training, which began at 2 weeks after first intraperitoneal injection. We determined the body weight change for each rat on days 1 and 21. Biochemical markers (lactate dehydrogenase [LDH], creatine kinase [CK], glutathion, aspartate transaminase [AST], and alanine transaminase [ALT]) concentration in the serum change of rats from all four groups was examined at the end of the experiment. Results: The results showed that the experimental group I and II showed a significant increase in body weight as compared with that of the control group (p<0.05). We observed that the biochemical markers (LDH, CK, glutathion, AST, and ALT) were improved in the experimental group I than the experimental group II (p<0.05). There was no difference between the experimental groups. Conclusions: In conclusion, our data suggest that low-intensity treadmill training applied after doxorubicin treatment protects against cardiotoxicity following treatment, possibly by enhancing antioxidant defenses and inhibiting cardiac muscle cell apoptosis.
The purpose of this study was to examine the most effective weight training (WT) intensity for the improvement of metabolic syndrome factors in overweight high school students. Sixty overweight high school students were randomly divided into 4 groups (15 subjects/group) according to WT intensity: A group - control group, B group - 40-55% repetition maximum (RM) group, C group - 60-75% RM group, and D group - 80-90% RM group. They exercised between 60-70 minutes a day, three times a week, for eight weeks. In order to determine the most effective WT intensity, five metabolic syndrome factors--waist size, fasting glucose, triglyceride (TG), high-density lipoprotein-cholesterol (HDL-C) and blood pressure--were measured for each subject prior to and after the experiment. Waist size decreased in all exercise groups, but the results were more prominent in the 40-55% RM and 60-75% RM groups. TG levels also decreased in all groups but results were more prominent in the 40-55% RM group. HDL-C levels in the 80-90% RM group were significantly higher than the control group. Groups did not show any significant difference in the diastolic blood pressure, but the 40-55% RM group's systolic blood pressure significantly decreased compared to other groups. Groups did not show significant difference in the fasting glucose level. These results indicate that lower-intensity weight training is generally more effective than the higher-intensity weight training in improving metabolic syndrome factors in overweight high school students and that the most effective WT intensity is 40-55% RM.
Journal of Fisheries and Marine Sciences Education
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v.16
no.2
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pp.156-162
/
2004
This study aimed to know the effects of three marine training items, swimming, rowing and yachting on pulse, lung capacity and weight. The experiment subjects were composed of ten each item and were tested for six days. The experiment groups were strictly controlled in eating time, food amount, sleeping time and training intensity. The level of training intensity was 70~80% of maximal pulse rate. In the training intensity of each item the speed was decided after examination in advance, and the trainees kept the speed during training. The contents of training were made up through enough examination. The conclusions were as follows. 1. The effect on pulse in average value showed the decrease of 1.80round/min swimming, 1.51round/min rowing, and 0.11round/min yachting, but it was not admitted as significant difference. And in average value, swimming showed the decrease of 0.26round/m than rowing and 1.69round/m than yachting. 2. The effect on lung capacity showed the increase of 66.66cc swimming, 42.97cc rowing, and 4.22cc yachting, but there was no significant difference. And the average value of swimming showed the increase of 23.66cc than rowing, and 62.44cc than yachting. 3. The effect on weight showed decrease of 3.45g in swimming, 3.24g in rowing, and 2.07g in yachting. Swimming and rowing proved to have significant difference (p<.05). And in average value, swimming showed the decrease of 1.175g than rowing, and 1.38g than yachting. On the whole, in all experiment items, pulse, lung capacity and weight, the change was in the order of swimming, rowing and yachting after experiments.
PURPOSE: This study investigated the protective role of high-intensity interval training against acute liver injury induced by D-galactosamine (D-Gal)/lipopolysaccharide (LPS). METHODS: A total of 30 male BALB/c mice aged 5-week were randomly assigned to high-intensity, interval training group (EX, n=10) or control group in cage (Non-EX, n=20) for 10 weeks. Peritoneal injection of D-Gal (700 mg/kg body weight) and LPS ($10{\mu}g/kg$ body weight) was applied to induce acute liver injury, and liver tissue was harvested 6 hours after the injection. Hematoxylin and Eosin (H&E) staining was used for liver histology. Real-time PCR was used to quantify expression of pro-inflammatory and anti-inflammatory genes in the liver. RESULTS: The liver histology showed that D-Gal/LPS treatment resulted in hepatic damage and increased number of neutrophils in conjunction with upregulation of hepatic IL-6 and $TNF-{\alpha}$ mRNAs and downregulation of hepatic $PPAR{\alpha}$ and SIRT1 mRNAs. On the other hand, the 10-week interval training resulted in a significant improvement in cardiorespiratory fitness assessed as run time to exhaustion on a treadmill. In addition, the interval training attenuated the D-Gal/LPS-induced liver damage and increased number of neutrophil in conjunction with downregulation of hepatic IL-6 and $TNF-{\alpha}$ mRNAs and upregulation of hepatic $PPAR{\alpha}$ and SIRT1 mRNAs. CONCLUSIONS: This study suggests that high-intensity interval training suppresses the D-Gal and LPS-induced acute liver damage and inflammatory responses.
Objectives: The purpose of this study is to investigate the effect of the aerobic exercise and weight training combined with VLCD(very low calorie diet) and chegameuyiin-tang(體減薏苡仁湯) on the change of the body composition during 15 days of hospitalization treatment. Methods: Twenty four female obese patients were observed. Exercise regimen was composed with aerobic exercise and weight training program, and the intensity of aerobic exercise were 50% HRmax(maximal heart rate) twice time a day and weight training were 50% 1RM(one repetition maximum) a day. All subjects diet regimen was VLCD of 600kcal/day. Results & Conclusions. 1. There was no significant difference between the aerobic exercise and the weight training groups in the change of body weight, fat mass, and percent body fat, waist-hip ratio, body mass index and resting metabolic rate. 2. In the comparison of the change rate of FFM(fat free mass), weight training group preserved FFM better than aerobic-exercise-only-group with no statistical significance.
Purpose: The purpose of this study was to investigate the exercise effect of two types of training with a recumbent cycle ergometer on ankle muscle strength (dorsiflexor strength, DFS; dorsiflexor strength/weight, DFS/kg; plantar flexor strength, PFS; and plantar flexor strength/weight, PFS/kg) in healthy male subjects. Methods: Twenty-three healthy males (27.91±8.66 yr) were randomly allocated into two groups (high-intensity interval training (HIIT), and aerobic exercise training (AET) after the first measurement. The subjects were trained for 24 sessions (40 min/rep, three times/week) and ankle strength was measured for a second time. Two-way mixed model analysis of variance (ANOVA) was used to identify significant differences between changes in ankle muscle strength between before and after training (within factors) in the HIIT and AET groups (between factors). The statistical significance level was set at α=0.05. Results: In both HIIT and AET groups, all variables of ankle muscle strength were significantly increased after training compared to before training (p=0.001). However, there were no differences in all variables of ankle strength between the HIIT and AET group (p>0.05). Conclusion: Both types (HIIT and AET) of recumbent cycle exercise training could be effective training methods to increase ankle muscle strength in healthy individuals, and the HIIT type with high intensity and low frequency pedaling could be recommended more to strengthen ankle muscles.
Matsui, A.;Katsuki, R.;Fujikawa, H.;Kai, M.;Kubo, K.;Hiraga, A.;Asai, Y.
Asian-Australasian Journal of Animal Sciences
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v.17
no.7
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pp.973-979
/
2004
The objectives of this study were to evaluate the digestible energy intake and energy expenditure in yearling horses on different training protocols (uphill- and level-track exercise training protocols). Twenty-four thoroughbred yearlings (12 males and 12 females, aged 27.0$\pm$0.9 months) were divided into two groups based on their training on two different tracks: the uphill (with a gradient of about 3%) training group (uphill training) and the level training group (level training). The digestible energy (DE) intake and energy expenditure (EE) during exercise were measured in both the groups. It was found that the DE intake in the uphill training and the level training groups was 5.1$\pm$3.1 and 36.9$\pm$4.8 Mcal/day, respectively. The EE during exercise in the two groups was 3.05$\pm$0.51 and 2.07 $\pm$0.56 Mcal, respectively. Thus, there was a significant difference in the EE (p<0.05), but not in the DE intake between the animals of the two training groups. The EE for a given intensity of exercise was greater in the uphill training group than in the level training group, but the DE intake was not affected by the exercise intensity. The DE intake was not generally affected by the intensity of exercise in this study, but a daily negative gain of body weight was observed in the uphill training group, particularly in the females. Thus, the energy requirement may be higher in yearlings undergoing uphill training than in those undergoing level training.
The purpose of this study was to investigate the effect of bicarbonate intake on blood variables during high-intensity training of sprinters. 30 male/female elites with more than 3 years of experience that are registered to S city as a sprinter was categorized into three groups: control group, training group, and HCO3- and training group. Training group and HCO3- and training group went through a high-intensity exercise program (80-90% HR max) which escalated every 2-3 weeks, for 90 minutes at a time, 5 days a week, 8 weeks in total. HCO3- and Training group took in 300mg of bicarbonate per one kilogram of body weight, in 90 minutes before the start of the high-intensity exercise program, once a day for 8 weeks. As a result of the study, the effect of bicarbonate intake on blood variables during high-intensity training of sprinters showed a positive effect on the increase of pH and the decrease of lactic acid in HCO3- and training group. Also, the increase of Ca2+, Na+, K+ was shown in training group and HCO3- and training group, whereas there were no indications of significant change in Mg2+ in all three groups. It can be confirmed that the intake of bicarbonate during high-intensity training shows effective changes in the increase of pH and the decrease in lactic acid among changes in blood variables. Therefore, it can be seen that the intake of bicarbonate during high-intensity exercise is effective in improving exercise capacity.
Purpose: The purpose of this study is to identify the effect of 24-week sensory integration activity training on fitness of children with intellectual disability. Research design, data, and methodology: The subjects were 10 children with intellectual disability, 60 min training of sensory integration activity for 24 weeks. Obesity, cardiovascular endurance, muscular strength and muscle endurance were measured pre and post training. Frist, characteristics of subjects were measured with age, height, weight, IQ and SQ. Second, the subjects then performed sensory integration activity training for 24 weeks. Last, weight, strength, endurance, cardiovascular endurance and flexibility were measured. Data were calculated for average and standard deviation by SPSS 25.0 statistic program, and dependent sample t-test was processed to analyze the change between pre and post training. All statistical significance level was set to 0.5. Results: The result was shown that weight, strength and endurance changes between pre and post were significant. However, cardiovascular endurance, flexibility changes between pre and post were not significant. Conclusions: The lack of training frequency of 60 minute per week were acknowledged per week from this result. In future research, increased intensity and frequency are need for an in-depth and meaningful study and the measured data can be used basic information for the study.
Six volunteers (mean $age=25.7{\pm}1.7$, $height=173{\pm}1.9$ and $weight=63.4{\pm}2.3{\;}kg$) participated in a graded exercise test and one hour of basic form of ChunDoSunBup (CDSB) Qi-training to investigate the cardiorespiratory responses and exercise intensity of Qi-training, a Korean traditional psychosomatic training. In the maximal exercise, the trainee showed $96.2{\pm}8.89{\;}l/min$ in ventilation (VE), $46.0{\pm}4.4$ in breath frequency (BF), $1.31{\pm}0.05$ in respiratory exchange ratio (RER), $180.7{\pm}3.0$ in heart rate (HR), and $2.6{\pm}1.1{\;}l/min$ or $40.7{\pm}2.3{\;}ml/kg/ml$ in oxygen consumption $(VO_2)$. Qi-training induced significant changes in BF, RER, HR, and $VO_2$. The exercise intensity of Qi-training were 42.3%, 46.9% and 38.7% of $HR_{max}$ during the sound exercise, slow motion (haeng-gong) and meditation respectively and the average was 46.2% of $HR_{max}$. We conclude that Qi-training is an aerobic exercise of a light (mild) intensity exercise, and it leads to decrease the metabolic rate in the trainee by breathing efficiently and relaxing them. In addition, Qi-training may affect cardiorespiratory function of BF, RER, HR and $VO_{2max}$ in trainees.
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