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A Study on Red Cell Protoporphyrin Concentration and Iron Metabolism (적혈구(赤血球) Protoporphyrin과 철분대사(鐵分代謝)에 관(關)한 연구(硏究))

  • Cho, Kyung-Hwan;Tchai, Bum-Suk
    • Journal of Nutrition and Health
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    • v.7 no.3
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    • pp.1-13
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    • 1974
  • The relative state of human iron storage may be ascertained more reliably through determination of the serum iron, iron binding capacity, transferrin saturation and absorption of radioactive iron in conjunction with studies of red cell morphology than from the study of red cell morphology alone. Recent investigations have shown that there is an increase in red cell protoporphyrin concentration in iron deficiency anemia. The significance of the red cell protoporphyrin has been discussed greatly during the years since its discovery. Two of the main factors which appear to influence the amaunt of protoporphyrin are increased erythropoiesis and factors interfering with the utilization of iron in the synthesis of hemoglobin, and iron deficiency. Recently Heller et al. have described a simplified method for blood protoporphyrin assay and this technique could be used assess nutritional iron status, wherein even minor insufficiencies are detectable as increased protoporphyrin concentrations. Based on the evaluation of the relationship between nutritional iron status and red cell protoporphyrin as an index suitable for the detection of the iron deficiency is described in this paper. RESULTS 1. Hemoglobin Concentrations and Anthropometric Measurements. The mean and standard deviations of the various anthropometric measurements of different age and sex groups are shown in table 1. There measurements have been compared with the Korean Standard. In the absence of local standards for arm circumference and skin-fold thickness over triceps, they have been compared with the standard from Jelliffe. Table 2,3, and 4 give anthropometric measurements and frequency (%) of anemia in children surveyed. The mean height of the children studid was 10 to 20 percent; below the Korean Standard. The distribution of height below 80 percent of the Standard was 21.2 percent, however, among anemic group this percentage was 27.7 percent. In general, the mean weight of the children was 10 to 15 percent below the Korean Standard. The percentage of children with weight less than 80 percent of the Standard was about 35 percent. But in the anemic group of the children, this percentage was 44 percent. The mean arm circumference was about 15 percent lower than the Jelliffe's standard. 61.2 percent of the children had values of arm circumference below 80 percent of the standard. Children with low hemoglobin levels, this percentage was 80 percent. The mean skinfold thickness over the triceps of the children studied was about 25 Percent lower than the Jelliffe's standard and 61.2 percent of the children had the value less than 80 percent of the standard. Among anemic children, this percentage was 70.8%. As may be seen from table 5, the mean hemoglobin concentration of the total group was 11.3g/100ml. Hemoglobin concentration was less than 11.0g/100ml. in 65(36.5%) of the 178 children. The degree of anemia in most of these children was mild with a hemoglobin level of less than 8.0g/100ml. found in only one child. In general, the prevalence of anemia was high in female children than male and decreased its frequency with increasing age. Relatively close relationship was observed between hemoglobin level and anthrophometric measurements especially high between arm circumference and skinfold thickness and hemoglobin but very low in height and low in weight and hemoglobin level, estimated by chi-square value. II. Serum iron, Transferrin saturation (1) Serum iron, and transferrin saturation Serum iron, transferrin saturation and red cell protoporphyrin concentrations were estimated in sub-sample of 84 children from 1 to 6 years and 24 older children between 7 and 13 years of age. The findings are presented in table 6. The mean serum iron concentration of the total group was 59ug/100ml. However, the level incrased with age from 36.6ug/100ml. (1-3years) to 80.8ug/100ml. (7-13 years). 60 percent of these children had a serum iron level less than 50ug/10ml. in the 1-3 years age group and 31.4 percent for 4-6 years group. These contrast with the finding of 12.5 percent anemic children in the 7-13 years age group. The mean transferrin saturation for the total group was 18.1 percent and frequency of anemia by transferrin saturation was observed same pattern as serum iron concentration. (2) Red cell protoporphyrin concentrations. (a) Red cell protoporphrin levels of children: Red cell protoporphyrin and other biochemical data are shown in table 4. The mean concentration in red cell of all children was fround 46.3ug/100ml. RBC. and differences with age groups were observed; in the age group 1-3 years, the mean concentration was $59.5{\pm}32.14$ ug/100ml. RBC; 4-6 years $44.1{\pm}22.57$ ug/100ml. RBC. and 7-13 years, $39.0{\pm}13.56$ ug/100ml. RBC. (b) Normal protoporphyrin values in adults: It was observed that in 10 normal adult males studied here the level of protoporphyrin in red cell ranged from 18 to 54 ug/100ml. RBC. and the mean concentration was $47.5{\sim}14.47$ ug/100ml. RBC. Other biochemical determination made on the same subjects are presented in table 8. (c) Red tell protoporphyrin concentration of occupational blood donors: The results of analyses for red cell protoporphyrin as well as serum iron, transferrin saturation and hemoglobin in the 76 blood donors are presented in table 7 and 8. In this experiment, donors were selected at random, however, most of them bled repeatedly because of poor economic situation, I doubt. Table 9 shows the distribution of red cell protoporphyrin concentration and hemoglobin concentration of occupational donors. The mean hemoglobin value for the total was 11.9 g/100 ml. When iron deficiency anemia is defined as a transferrin saturation below 15%, prevalence of anemia was 47.4 percent and the mean serum iron was 27.1ug/100ml. and red cell protoporphyrin, 168.3ug/100ml. RBC. However, mean serum iron and protoporphyrin concentration of above 15% transferrin saturation were 11.6 ug/100 ml. and 58.8 ug/100 ml. RBC. respectively. The mean Protoporphyrin concentration of non-anemic (above 15% transferrin saturation) donors was slightly higher than the results of normal adult males.

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Comparative Anatomic Structures of Nonhuman Primate Lungs 2. Tracheobronchial Geometry and Lung Lobe Weight (영장동물폐(靈長動物肺)의 비교해부학적연구(比較解剖學的硏究) 2. 기관(氣管) 및 기관지(氣管枝)의 기하학적계측(幾何學的計測)과 폐중량(肺重量)에 관(關)한 연구(硏究))

  • Kim, Moo Gang;Kim, James C.S.
    • Korean Journal of Veterinary Research
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    • v.19 no.1
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    • pp.9-15
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    • 1979
  • Anatomical measurements were made at the necoropsy and sacrifice in a group of 41 adult female Rhesus monkey to determine the 34 characteristcs found in tracheas snd bronchus. Table 1, 2, 3, 4, and figure 1 were therefore prepared as a guide in the further use for illustrating monkey lung research. Summary of this report is as follows: 1. Accurate Knowledge of these measurements may have some value in pulmonary dissection and reconstructive procedures. 2. These studies may provide a more accurate determination of the monkey lungs. 3. The right and left bronchus length of the monkey is shorter than fornd in man. 4. The left bronchus length is more longer than the rrght bronchas. 5. There were large variation among the weight of adult female Rhesus monkey.

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The Construction of Earthquake Resistance and Hazardous Reduction Suitability Evaluation Systems for Comprehensive Parks (공원녹지 공간의 지진대피 기능 적절성 평가체계 연구)

  • Cao, Lin-Sen;Zhang, Zhong-Feng;Kang, Tai-Ho
    • Journal of the Korean Institute of Landscape Architecture
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    • v.46 no.1
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    • pp.86-95
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    • 2018
  • The lack of research on the suitability of park green spaces as a form of earthquake shelter leads to difficultiesin highlighting the functions of these shelters. In this study, the weight value and priority of 27 indexes derived from previous studies are calculated by the AHP method and then a score table was established via a transformed score method. The final evaluation grade is divided into five levels: very inadequate, inadequate, general, adequate, highly adequate. Finally, indexes that were difficult to judge were explained. Based on this, the suitability evaluation of park green spaces as a form of earthquake shelter can be performed. The evaluation results can reflect the advantages and disadvantages of park green space as a form of earthquake shelter and indicate directionsfor construction in the future.

Comparison of Robotic Tilt-table Training and Body Weight Support Treadmill Training on Lower Extremity Strength, Balance, Gait, and Satisfaction with Rehabilitation, in Patients with Subacute Stroke (아급성기 뇌졸중 환자의 다리근력, 균형, 보행, 재활만족도에 대한 로봇 보조 기립경사대 훈련과 체중지지 트레드밀 훈련의 효과 비교)

  • Kwon, Seung-Chul;Shin, Won-Seob
    • Journal of the Korean Society of Physical Medicine
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    • v.15 no.4
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    • pp.163-174
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    • 2020
  • PURPOSE: This study examined the effects of Robot Tilt-table Training (RTT) on the lower extremity strength, balance, gait, and satisfaction with rehabilitation, in patients with subacute stroke (less than six months after stroke onset), and requiring intensive rehabilitation. METHODS: A total of 29 subacute stroke patients were divided into an RTT group (n = 14) and a Body Weight Support Treadmill Training (BWSTT) group (n = 15). The mean age of patients was 62 years. RTT and BWSTT were performed for four weeks, three times a week, for 30 minutes. Isometric strength of the lower extremities before and after intervention was compared by measuring the maximal voluntary isometric contraction of the lower extremity muscles. To compare the balance function, the center of pressure (COP) path-length and COP velocity were measured. Timed Up & Go test (TUG) and 10 Meter Walking Test (10 MWT) were evaluated to compare the gait function. A satisfaction with rehabilitation survey was conducted for subjective evaluation of the subject's satisfaction with the rehabilitation training imparted. RESULTS: In the intra-group comparison, both groups showed significant improvement in lower extremity strength, balance, gait, and satisfaction with rehabilitation, by comparing the parameters before and after the intervention (p < .05). Comparison of the amount of change between groups revealed significant improvement for all parameters in the RTT group, except for the 10 MWT (p < .05). CONCLUSION: Both groups are effective for all variables, but the RTT group showed enhanced efficacy for variables such as lower extremity strength, balance, gait, and satisfaction with rehabilitation, as compared to the BWSTT group.

Improvements in e-Food Exchange of commonly used Foods and search System (ENECC/E-Food Exchange) based on Internet (인터넷 기반의 일상식품의 e-식품교환량(ENECC/E-Food Exchange)과 검색 시스템 개선)

  • Hong, Sun-Myeong;Jo, Hui-Seon;Kim, Gon
    • Journal of the Korean Dietetic Association
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    • v.10 no.2
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    • pp.129-142
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    • 2004
  • The food exchanges are frequently used to nutrition education and counseling for diabetes, weight control, hyperlipidema and etc. But it is difficult to find out food exchange lists with food exchange groups in the food composition table. This study was conducted to select e-food exchange of commonly used foods(456 foods) and improve search system based on internet. Also, the e-food exchange database was developed as having the proximate composition, mineral and vitamin content such as energy, moisture, protein, fat, carbohydrate, ash, calcium, phosphorus, iron, sodium, potassium, retinol equivalent, retinol, a-carotene, thiamin, riboflavin, niacin, ascorbic acid, refuse per 100g of each food. The e-food exchange database developed is basically based on the 6th food composition table(2001) of the National Rural Living Science Institution in Rural Development Administration, Korea. The 456 commonly used foods or 2,262, all foods can be searched easily in a new system. A specific food of e-food exchange can be searched by a given set of food groups or food name and can give information about food one exchange lists, weight and nutrient value per 100g of each food user-friendly on internet. It can be used to make a nutritionally balanced meal plan, nutrition education and counseling.

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Variation of Dynamic Earth Pressure Due to Sliding of Retaining Walls (옹벽의 활동에 따른 배면 동적토압의 변화)

  • Yoon Suk-Jae;Kim Sung-Ryul;Hwang Jae-Ik;Kim Myoung-Mo
    • Journal of the Korean Geotechnical Society
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    • v.21 no.8
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    • pp.55-61
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    • 2005
  • Mononobe-Okabe method is generally used to evaluate dynamic earth pressure for the seismic design of retaining walls. However, Mononobe-Okabe method does not consider the effects of dynamic interactions between backfill soil and walls. In this research, shaking table tests on retaining walls were performed to analyze the phase and magnitude of dynamic earth pressure. The unit weight of walls, the amplitude of input acceleration and the base friction coefficient of walls were varied to analyze the influence of these factors on the dynamic earth pressure. Test results showed that the dynamic earth pressure was 180 degrees out of phase with the wall inertia force for the low sliding velocity of the wall, whereas small peaks of the dynamic earth pressure, which are in phase with the wall inertia force, were developed for the high sliding velocity of the wall. The amplitude of dynamic earth pressure was proportional to that of wall acceleration and the unit weight of the wall. In addition, the dynamic earth forces calculated by the Mononobe-Okabe method were the upper limit of the dynamic earth pressures.

The Long Term Effects of Fairly Low-level of Supplemental Fat on the Productive Performance of Commercial Layers

  • Bozkurt, Mehmet;Kucukyilmaz, Kamil;Cabuk, Metin;Catli, Abdullah Ugur
    • Asian-Australasian Journal of Animal Sciences
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    • v.25 no.4
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    • pp.524-530
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    • 2012
  • Laying hens were fed commercial diets added with supplemented fat (SFAT) at 0.6, 1.2, and 1.8% in order to study the long term dietary effects - on - their productive performance from 22 to 75 wk of age. Five hundred and seventy six Single Comb White Leghorn hens were assigned to one of the four dietary treatments. The experimental phase consisted of three periods of 18 wk each. The final body weight and gain of hens fed on diets with SFAT at 1.2% and 1.8% were lower (p<0.05) than those hens given no SFAT. The SFAT at the 1.2% and 1.8% levels improved egg production rate, egg weight and mass, as well as FCR. Mortality and feed consumption were not affected by dietary SFAT. Administration of a diet with SFAT significantly decreased the cracked-broken egg ratio (p<0.01). The beneficial effects of SFAT on egg production performance were particularly more pronounced at intermediate and later ages. Hence, SFAT by period interactions were significant for all traits studied except feed intake. Hens fed SFAT deposited significantly higher abdominal fat than those on the no-SFAT diet. As a result, SFAT at 1.2% and 1.8% inclusion levels provided benefits in terms of efficient table egg production.

A Study on Side Slope Determination of Earth Dam (EARTH DAM의 비탈면 기울기 결정에 관한 연구)

  • 이원희;김시원
    • Magazine of the Korean Society of Agricultural Engineers
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    • v.23 no.1
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    • pp.86-102
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    • 1981
  • The soil test data of 28 earth dams, scheduled to be constructed in Kore3, were selected for this study. The safety factors of their side slops were computed using Fellenius' "slice Method" by computer. The results summarized in this study are as follows; 1. Dam sections can be easily determined by fig.10 without a time consuming trial and error calculations of assumed sections. 2. For the economical design of earth dam sections, it was found that more cohesive soil was suitable for lower dams(dam height less than 25m) and soils with a higher friction angle was better for higher dams 3. In the case that used soil materials have the same Internal friction angle, side slope increase was almost same. 4. The relationship between side slope and friction angle was found as log.S=a tan ø+b (Fig. 7) 5. The relationship between side slope and cohesion (c) was also found as log. S=a c+b (Fig. 8) 6. The change of safety factors due to the change of central core materials was very little (Table-2) 7. The decrease of safety factors according to the unit weight increase of embankment materials was negligible. 8. In general the relationship between the wet unit weight and the saturated unit weight was r sat = (rt)$^2$+0. 140. This study will contribute to the determination of economic and safe planning and designing of earth dams, embankments and cutting side slopes.

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Optimum Design of the Friction Stir Welding Process on A6005 Extruded Alloy for Railway Vehicles to Improve Mechanical Properties (마찰 교반 용접된 철도 차량용 A6005 압출재의 기계적 성능 향상을 위한 최적 공법 설계)

  • Won, Si-Tea;Kim, Weon-Kyong
    • Journal of Welding and Joining
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    • v.27 no.5
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    • pp.81-87
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    • 2009
  • Recently, extruded aluminium-alloy panels have been used in the car bodies for the purpose of the light-weight of railway vehicles and FSW(Friction Stir Welding), which is superior to the arc weldings, has been applied in the railway vehicles. This paper presents the optimum design of the FSW process on A6005 extruded alloy for railway vehicles to improve its mechanical properties. Rotational speed, welding speed and tilting angle of the tool tip were chosen as design parameters. Three objective functions were determined; maximizing the tensile strength, minimizing the hardness and maximizing the difference between the normalized tensile strength and hardness. The tensile tests and the hardness tests for fifteen FSW experiments were carried out according to the central composite design table. Recursive model functions on three characteristic values, such as the tensile strength, the hardness difference(${\Delta}Hv$) and the difference of normalized tensile strength and ${\Delta}Hv$, were estimated according to the classical response surface analysis methodology. The reliability of each recursive function was verified by F-test using the analysis of variance table. Sensitivity analysis on each characteristic value was done. Finally, the optimum values of three design parameters were found using Sequential Quadratic Programming algorithm.

Development of Laminar Box Manufacturing Technique for Earthquake Engineering (내진 연구를 위한 전단상자 제작기술 개발)

  • 이용재
    • Proceedings of the Earthquake Engineering Society of Korea Conference
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    • 2001.04a
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    • pp.100-107
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    • 2001
  • One major problem in the model testing is the boundary effect and size effect caused by the limit in the size of the container. To overcome this problem, various types of laminar boxes are gradually manufactured and used in the shaking table test, which ideally has zero stiffness to horizontal shear. In this study, a small-scale laminar box is manufactured, which is composed of 6 thin aluminum rectangular hollow plates, and its inside dimensions are 300 mm length by 200 mm width by 350 mm depth. Shaking table tests are performed both with the laminar box and the rigid box under the same conditions, where displacements and accelerations are measured at various points of the box and model ground. As result of analyzing the measured data, during the propagation of input seismic motion from the bottom to the ground surface, the relative displacement of the model ground and the amplification of acceleration is hardly amplified in the rigid box. Because of the effect of stress waves reflecting from the rigid wall, the acceleration is slightly decreased at the edge in the rigid box. The laminar box, manufactured in this study, has a problem in that the soil behavior at the edge of ground surface is affected by the inertia force of the top layer due to its excessive self-weight.

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