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Application of Off-axis Correction Method for EPID Based IMRT QA (EPID를 사용한 세기조절방사선치료의 정도관리에 있어 축이탈 보정(Off-axis Correction)의 적용)

  • Cho, Ilsung;Kwark, Jungwon;Park, Sung Ho;Ahn, Seung Do;Jeong, Dong Hyeok;Cho, Byungchul
    • Progress in Medical Physics
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    • v.23 no.4
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    • pp.317-325
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    • 2012
  • The Varian PORTALVISION (Varian Medical Systems, US) shows significant overresponses as the off-center distance increases compared to the predicted dose. In order to correct the dose discrepancy, the off-axis correction is applied to VARIAN iX linear accelerators. The portal dose for $38{\times}28cm^2$ open field is acquired for 6 MV, 15 MV photon beams and also are predicted by PDIP algorithm under the same condition of the portal dose acquisition. The off-axis correction is applied by modifying the $40{\times}40cm^2$ diagonal beam profile data which is used for the beam profile calibration. The ratios between predicted dose and measured dose is modeled as a function of off-axis distance with the $4^{th}$ polynomial and is applied to the $40{\times}40cm^2$ diagonal beam profile data as the weight to correct measured dose by EPID detector. The discrepancy between measured dose and predicted dose is reduced from $4.17{\pm}2.76$ CU to $0.18{\pm}0.8$ CU for 6 MV photon beam and from $3.23{\pm}2.59$ CU to $0.04{\pm}0.85$ CU for 15 MV photon beam. The passing rate of gamma analysis for the pyramid fluence patten with the 4%, 4 mm criteria is improved from 98.7% to 99.1% for 6 MV photon beam, from 99.8% to 99.9% for 15 MV photon beam. IMRT QA is also performed for randomly selected Head and Neck and Prostate IMRT plans after applying the off-axis correction. The gamma passing rare is improved by 3% on average, for Head and Neck cases: $94.7{\pm}3.2%$ to $98.2{\pm}1.4%$, for Prostate cases: $95.5{\pm}2.6%$, $98.4{\pm}1.8%$. The gamma analysis criteria is 3%, 3 mm with 10% threshold. It is considered that the off-axis correction might be an effective and easily adaptable means for correcting the discrepancy between measured dose and predicted dose for IMRT QA using EPID in clinic.

Evaluation of horticultural traits and genetic relationship in melon germplasm (멜론 유전자원의 원예형질 특성 및 유연관계 분석)

  • Jung, Jaemin;Choi, Sunghwan;Oh, Juyeol;Kim, Nahui;Kim, Daeun;Son, Beunggu;Park, Younghoon
    • Journal of Plant Biotechnology
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    • v.42 no.4
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    • pp.401-408
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    • 2015
  • Horticultural traits and genetic relationship were evaluated for 83 melon (Cucumis melo L.) cultivars. Survey of a total of 36 characteristics for seedling, leaf, stem, flower, fruit, and seed and subsequent multiple analysis of variance (MANOVA) were conducted. Principal component analysis (PCA) showed that 8 principle components including fruit weight, fruit length, fruit diameter, cotyledon length, seed diameter, and seed length accounted for 76.3% of the total variance. Cluster analysis of the 83 melon cultivars using average linkage method resulted in 5 clusters at coefficient of 0.7. Cluster I consisted of cultivars with high values for fruit-related traits, Cluster II for soluble solid content, and Cluster V for high ripening rate. Genotyping of the 83 cultivars was conducted using 15 expressed-sequence tagged-simple sequence repeat (EST-SSR) from the Cucurbit Genomics Initiative (ICuGI) database. Analysis of genetic relatedness by UPGMA resulted in 6 clusters. Mantel test indicated that correlation between morphological and genetic distance was very low (r = -0.11).

Enhancement of the Chaperone Activity of Alkyl Hydroperoxide Reductase C from Pseudomonas aeruginosa PAO1 Resulting from a Point-Specific Mutation Confers Heat Tolerance in Escherichia coli

  • Lee, Jae Taek;Lee, Seung Sik;Mondal, Suvendu;Tripathi, Bhumi Nath;Kim, Siu;Lee, Keun Woo;Hong, Sung Hyun;Bai, Hyoung-Woo;Cho, Jae-Young;Chung, Byung Yeoup
    • Molecules and Cells
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    • v.39 no.8
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    • pp.594-602
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    • 2016
  • Alkyl hydroperoxide reductase subunit C from Pseudomonas aeruginosa PAO1 (PaAhpC) is a member of the 2-Cys peroxiredoxin family. Here, we examined the peroxidase and molecular chaperone functions of PaAhpC using a site-directed mutagenesis approach by substitution of Ser and Thr residues with Cys at positions 78 and 105 located between two catalytic cysteines. Substitution of Ser with Cys at position 78 enhanced the chaperone activity of the mutant (S78C-PaAhpC) by approximately 9-fold compared with that of the wild-type protein (WT-PaAhpC). This increased activity may have been associated with the proportionate increase in the high-molecular-weight (HMW) fraction and enhanced hydrophobicity of S78C-PaAhpC. Homology modeling revealed that mutation of $Ser^{78}$ to $Cys^{78}$ resulted in a more compact decameric structure than that observed in WT-PaAhpC and decreased the atomic distance between the two neighboring sulfur atoms of $Cys^{78}$ in the dimer-dimer interface of S78C-PaAhpC, which could be responsible for the enhanced hydrophobic interaction at the dimer-dimer interface. Furthermore, complementation assays showed that S78C-PaAhpC exhibited greatly improved the heat tolerance, resulting in enhanced1 survival under thermal stress. Thus, addition of Cys at position 78 in PaAhpC modulated the functional shifting of this protein from a peroxidase to a chaperone.

The Analysis of Chloride Ion of Ground Water in the West Coast District of Jeollabuk-Do using Spatial Interpolation (공간보간법을 이용한 전라북도 서해안 지역의 지하수 염소이온 분석)

  • Lee, Geun-Sang;Im, Dong-Gil;Choi, Yun-Woong;Cho, Gi-Sung
    • Journal of Korean Society for Geospatial Information Science
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    • v.19 no.4
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    • pp.23-33
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    • 2011
  • In this study, the data that examined the chloride ion concentration of ground water wells in the west coast of Jeollabukdo applying the GIS spatial estimation method were analyzed. In particular, through the designation of a validation point among ground water wells and then the analysis of error characteristics of the chloride ion concentration by each method of IDW (Inverse Distance Weight), Spline, and Kriging Interpolation method which is proper for estimating salt water intrusion was selected. The main conclusion from this study is as follows. First, as a result of analyzing the error characteristics of various spatial estimation methods by using the data from the chloride ion concentration of 485 ground water wells, the IDW method was found to be the most appropriate for estimating chloride ion concentration by salt water intrusion. Second, analyzing the average chloride ion concentration of the targeted regions has revealed that Gunsan-si with the record of $541mg/{\ell}$ did not meet water quality standards even for industrial use. Both Gimje-si and Gochang-gun satisfied drinking water quality standards and Buan-gun with $272mg/{\ell}$ was slightly below the standards for drinking water. Third, concerning the results of analysis according to administrative districts, as the areas adjacent to the west coast such as Daemyeong-dong, Joong-dong, Jangjae-dong and Guemam-dong in Gunsan-si are found to have very high chloride ion concentration, and both Hoehyeon-myeon and Daeya-myeon bounded by the Mankeong river did not meet water quality standards even for industrial use. From these facts, it is concluded that salt water intrusion has a great effect on Gunsan-si generally.

An Exploratory Study of Searching Human Body Segments for Motion Sensors of Smart Sportswear: Focusing on Rowing Motion (동작에 따른 피부변화 분석을 통한 동작센서 부착의 최적위치 탐색: 조정 동작을 중심으로)

  • Han, Bo-Ram;Park, Seonhyung;Cho, Hyun-Seung;Kang, Bokku;Kim, Jin-Sun;Lee, Joohyeon;Kim, Han Sung;Lee, Hae-Dong
    • Science of Emotion and Sensibility
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    • v.20 no.1
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    • pp.17-30
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    • 2017
  • Lots of interdisciplinary studies for fusion of high technologes and the other areas of research had been tried in these days. In sports training area, high technologies like a vital sign sensor or an accelerometer were adopted as training tools to improve the performance of the sports players. The purpose of this study is finding the proper locations on the human body for attaching the motion sensors in order to develop a smart sportswear which could be helpful in training players. The rowing was selected as a subject sport as lots of movements of the joint on human body could be seen in rowing motions. The players of rowing could be devided into two weight divisions, the lightweight and the heavyweight. In this study, the change rates of distance between markers on human skin as the players moved were took on the back, the elbow, the hip and the knee area on human body by 3D motion capturing system. The distances between markers and the differences between the lightweight and heavyweight were analyzed. Finally, this study provided the guide lines for designing a motion sensing smart sportswear.

Evaluation of Cable Impact Factor by Moving Vehicle Load Analysis in Steel Composite Cable-Stayed Bridges (차량 이동하중 해석에 의한 강합성 사장교 케이블의 충격계수 평가)

  • Park, Yong-Myung;Park, Jae-Bong;Kim, Dong-Hyun;Choi, Byung-Ho
    • Journal of Korean Society of Steel Construction
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    • v.23 no.2
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    • pp.199-210
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    • 2011
  • The cables in cable-stayed bridges are under high stress and are very sensitive to vibration due to their small section areas compared with other members. Therefore, it is reasonable to evaluate the cable impact factor by taking into account the dynamic effect due to moving-vehicle motion. In this study, the cable impact factors were evaluated via moving-vehicle-load analysis, considering the design parameters, i.e., vehicle weight, cable model, road surface roughness, vehicle speed, longitudinal distance between vehicles. For this purpose, two steel composite cable-stayed bridges with 230- and 540-m main spans were selected. The results of the analysis were then compared with those of the influence line method that is currently being used in design practice. The road surface roughness was randomly generated based on ISO 8608, and the convergence of impact factors according to the number of generated road surfaces was evaluated to improve the reliability of the results. A9-d.o.f. tractor-trailer vehicle was used, and the vehicle motion was derived from Lagrange's equation. 3D finite element models for the selected cable-stayed bridges were constructed with truss elements having equivalent moduli for the cables, and with beam elements for the girders and the pylons. The direct integration method was used for the analysis of the bridge-vehicle interaction, and the analysis was conducted iteratively until the displacement error rate of the bridge was within the specified tolerance. It was acknowledged that the influence line method, which cannot consider the dynamic effect due to moving-vehicle motion, could underestimate the impact factors of the end-cables at the side spans, unlike moving-vehicle-load analysis.

Prediction of Battery Performance of Electric Propulsion Lightweight Airplane for Flight Profiles (비행프로파일에 대한 전기추진 경량비행기의 배터리 성능 예측)

  • Kim, Hyun-Gi;Kim, Sungchan
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.5
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    • pp.15-21
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    • 2021
  • Electrically powered airplanes can reduce CO2 emissions from fossil fuel use and reduce airplane costs in the long run through efficient energy use. For this reason, advanced aviation countries such as the United States and the European Union are leading the development of innovative technologies to implement the full-electric airplane in the future. Currently, the research and development to convert existing two-seater engine airplanes to electric-powered airplanes are underway domestically. The airplane converted to electric propulsion is the KLA-100, which aims to carry out a 30-minute flight test with a battery pack installed using the engine mounting space and copilot space. The lithium-ion battery installed on the airplane converted to electric propulsion was designed with a specific power of 150Wh/kg, weight of 200kg, and a C-rate 3~4. This study confirmed the possibility of a 30-minute flight with a designed battery pack before conducting a flight test of a modified electrically propelled airplane. The battery performance was verified by dividing the 30-minute flight profile into start/run stage, take-off stage, climbing stage, cruise stage, descending stage, and landing/run stage. The final target of the 30-minute flight was evaluated by calculating the battery capacity required for each stage. Furthermore, the flight performance of the electrically propelled airplane was determined by calculating the flight availability time and navigation distance according to the flight speed.

Estimation of Illuminant Chromaticity by Equivalent Distance Reference Illumination Map and Color Correlation (균등거리 기준 조명 맵과 색 상관성을 이용한 조명 색도 추정)

  • Kim Jeong Yeop
    • KIPS Transactions on Software and Data Engineering
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    • v.12 no.6
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    • pp.267-274
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    • 2023
  • In this paper, a method for estimating the illuminant chromaticity of a scene for an input image is proposed. The illuminant chromaticity is estimated using the illuminant reference region. The conventional method uses a certain number of reference lighting information. By comparing the chromaticity distribution of pixels from the input image with the chromaticity set prepared in advance for the reference illuminant, the reference illuminant with the largest overlapping area is regarded as the scene illuminant for the corresponding input image. In the process of calculating the overlapping area, the weights for each reference light were applied in the form of a Gaussian distribution, but a clear standard for the variance value could not be presented. The proposed method extracts an independent reference chromaticity region from a given reference illuminant, calculates the characteristic values in the r-g chromaticity plane of the RGB color coordinate system for all pixels of the input image, and then calculates the independent chromaticity region and features from the input image. The similarity is evaluated and the illuminant with the highest similarity was estimated as the illuminant chromaticity component of the image. The performance of the proposed method was evaluated using the database image and showed an average of about 60% improvement compared to the conventional basic method and showed an improvement performance of around 53% compared to the conventional Gaussian weight of 0.1.

Development of Music Recommendation System based on Customer Sentiment Analysis (소비자 감성 분석 기반의 음악 추천 알고리즘 개발)

  • Lee, Seung Jun;Seo, Bong-Goon;Park, Do-Hyung
    • Journal of Intelligence and Information Systems
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    • v.24 no.4
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    • pp.197-217
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    • 2018
  • Music is one of the most creative act that can express human sentiment with sound. Also, since music invoke people's sentiment to get empathized with it easily, it can either encourage or discourage people's sentiment with music what they are listening. Thus, sentiment is the primary factor when it comes to searching or recommending music to people. Regard to the music recommendation system, there are still lack of recommendation systems that are based on customer sentiment. An algorithm's that were used in previous music recommendation systems are mostly user based, for example, user's play history and playlists etc. Based on play history or playlists between multiple users, distance between music were calculated refer to basic information such as genre, singer, beat etc. It can filter out similar music to the users as a recommendation system. However those methodology have limitations like filter bubble. For example, if user listen to rock music only, it would be hard to get hip-hop or R&B music which have similar sentiment as a recommendation. In this study, we have focused on sentiment of music itself, and finally developed methodology of defining new index for music recommendation system. Concretely, we are proposing "SWEMS" index and using this index, we also extracted "Sentiment Pattern" for each music which was used for this research. Using this "SWEMS" index and "Sentiment Pattern", we expect that it can be used for a variety of purposes not only the music recommendation system but also as an algorithm which used for buildup predicting model etc. In this study, we had to develop the music recommendation system based on emotional adjectives which people generally feel when they listening to music. For that reason, it was necessary to collect a large amount of emotional adjectives as we can. Emotional adjectives were collected via previous study which is related to them. Also more emotional adjectives has collected via social metrics and qualitative interview. Finally, we could collect 134 individual adjectives. Through several steps, the collected adjectives were selected as the final 60 adjectives. Based on the final adjectives, music survey has taken as each item to evaluated the sentiment of a song. Surveys were taken by expert panels who like to listen to music. During the survey, all survey questions were based on emotional adjectives, no other information were collected. The music which evaluated from the previous step is divided into popular and unpopular songs, and the most relevant variables were derived from the popularity of music. The derived variables were reclassified through factor analysis and assigned a weight to the adjectives which belongs to the factor. We define the extracted factors as "SWEMS" index, which describes sentiment score of music in numeric value. In this study, we attempted to apply Case Based Reasoning method to implement an algorithm. Compare to other methodology, we used Case Based Reasoning because it shows similar problem solving method as what human do. Using "SWEMS" index of each music, an algorithm will be implemented based on the Euclidean distance to recommend a song similar to the emotion value which given by the factor for each music. Also, using "SWEMS" index, we can also draw "Sentiment Pattern" for each song. In this study, we found that the song which gives a similar emotion shows similar "Sentiment Pattern" each other. Through "Sentiment Pattern", we could also suggest a new group of music, which is different from the previous format of genre. This research would help people to quantify qualitative data. Also the algorithms can be used to quantify the content itself, which would help users to search the similar content more quickly.

The Evaluation of TOPLATS Land Surface Model Application for Forecasting Flash Flood in mountainous areas (산지돌발홍수 예측을 위한 TOPLATS 지표해석모델 적용성 평가)

  • Lee, Byong Jua;Choi, Su Mina;Yoon, Seong Sima;Choi, Young Jean
    • Journal of Korea Water Resources Association
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    • v.49 no.1
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    • pp.19-28
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    • 2016
  • The objective of this study is the generation of the gridded flash flood index using the gridded hydrologic components of TOPLATS land surface model and statistic flash flood index model. The accuracy of this method is also examined in this study. The study area is the national capital region of Korea, and 38 flash flood damages had occurred from 2009 to 2012. The spatio-temporal resolutions of land surface model are 1 h and 1 km, respectively. The gridded meteorological data are generated using the inverse distance weight method with automatic weather stations (AWSs) of Korea Meteorological Administration (KMA). The hydrological components (e.g., surface runoff, soil water contents, and water table depth) of cells corresponding to the positions of 38 flood damages reasonably respond to the cell based hourly rainfalls. Under the total rainfall condition, the gridded flash flood index shows 71% to 87% from 4 h to 6 h in the lead time based on the rescue request time and 42% to 52% of accuracy at 0 h which means that the time period of the lead time is in a limited rescue request time. From these results, it is known that the gridded flash flood index using the cell based hydrological components from land surface model and the statistic flash flood index model have a capability to predict flash flood in the mountainous area.