• 제목/요약/키워드: Web searches

검색결과 128건 처리시간 0.021초

Updated Assessment of the Association of the XRCC1 Arg399Gln Polymorphism with Lung Cancer Risk in the Chinese Population

  • Yang, Hai-Yan;Yang, Si-Yu;Shao, Fu-Ye;Wang, Hai-Yu;Wang, Ya-Dong
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권2호
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    • pp.495-500
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    • 2015
  • Background: Published studies have reported relationships between X-ray repair cross-complementing group 1 (XRCC1) Arg399Gln polymorphism and lung cancer risk in Chinese population. However, the epidemiological results remained controversial. The objective of this study was to clarify the association of XRCC1 Arg399Gln polymorphism with lung cancer risk in the Chinese population. Materials and Methods: Systematic searches were performed through the database of Medline/Pubmed, Web of Science, Embase, CNKI and WanFang Medical Online. Odds ratios (ORs) with 95% confidence interval (95%CI) were calculated to estimate the strength of the association. Results: Overall, we observed an increased lung cancer risk among subjects carrying XRCC1 codon 399 Gln/Gln genotype (OR=1.36, 95%CI: 1.09-1.71) in the Chinese population on the basis of 19 studies with 5,416 cases and 5,782 controls. We did not observe any association between XRCC1 codon 399 Arg/Gln and Arg/Gln+Gln/Gln polymorphisms and lung cancer risk (OR=1.00, 95%CI: 0.92-1.08 and OR=1.05, 95%CI: 0.97-1.13, respectively). Limiting the analysis to studies with controls in agreement with Hardy-Weinberg equilibrium (HWE), we observed an increased lung cancer risk among subjects carrying XRCC1 codon 399 Gln/Gln genotype (OR=1.18, 95%CI: 1.01-1.38). When stratified by source of control, we observed an increased lung cancer risk among subjects carrying XRCC1 codon 399 Arg/Gln+Gln/Gln genotype on the basis of hospitalized patient-based controls (OR=1.21, 95%CI: 1.04-1.42) and among subjects carrying XRCC1 codon 399 Gln/Gln genotype on the basis of healthy subject-based controls (OR=1.22, 95%CI: 1.04-1.43). Conclusions: Our findings indicated that certain XRCC1 Arg399Gln variants might affect the susceptibility of lung cancer in Chinese population. Larger sample size studies are required to confirm our findings.

대한한의학회지 및 대한한의학회 산하 정회원 학회의 학술진흥재단 등재지에 대한 비염 임상연구의 체계적 고찰 (A Systematic Review from the Journals under the Korean Oriental Medical Society)

  • 이규선;박동희;김계은;방지현;김재환;최준용;정희재;정승기
    • 대한한의학회지
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    • 제31권5호
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    • pp.1-11
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    • 2010
  • Objectives: This study aimed to evaluate any clinical studies regarding rhinitis published by the Korean Oriental Medical Society and its sub-societies for future rigorous clinical research. Methods: Every article relevant to rhinitis was initially obtained from journals of the Korean Oriental Medical Society and its sub-societies by electronic search at journal web sites or manual searches. Journals were limited to those registered with the Korea Research Foundation. From initial findings, two independent reviewers selected clinical articles and these articles were further analyzed separately by predefined criteria according to prospective and retrospective studies. For prospective studies, quality assessment was also conducted. Results: From 36 initially obtained articles, 17 were finally analyzed. 2 articles were randomized controlled studies, 6 articles were prospective whereas 9 were retrospective. In the prospective articles, there were no randomized controlled trials and the other non-randomized studies had no control group with several problems of quality regarding pre-calculated study size and unbiased assessment. None of the retrospective studies described rhinitis diagnosis objectively and outcome measures were either non-relevant to rhinitis or non-validated. Conclusions: Further well-designed randomized controlled studies for rhinitis are mandatory and more rigorous non-randomized controlled studies should be conducted.

MVCC 지원 스킵 리스트의 범위 탐색 향상 기법 (An Enhancing Technique for Scan Performance of a Skip List with MVCC)

  • 김이주;이은지
    • 한국인터넷방송통신학회논문지
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    • 제20권5호
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    • pp.107-112
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    • 2020
  • 본 논문에서는 LSM-tree 기반 키밸류 스토어에서 인메모리 데이터 관리를 위해 사용되는 스킵 리스트에 대한 연구를 수행하였다. 키밸류 스토어에서 사용되는 스킵 리스트는 덮어쓰기를 허용하지 않고 삽입만으로 모든 변경을 처리하는 삽입 기반 스킵 리스트이다. 이러한 동작 방식은 스냅샷 분리(Snapshot Isolation)을 통해 다중 읽기/쓰기 요청을 동시다발적으로 처리할 수 있는 MVCC(Multi-Version Concurrency Control)을 지원할 수 있다. 그러나 중복된 키가 다수 스킵 리스트에 존재함에 따라 리스트 탐색 시 불필요한 노드 방문으로 성능이 심각하게 저하될 수 있다. 특히 특정 범위의 데이터를 집합적으로 탐색하는 범위 탐색(Range Query)나 스캔(Scan) 연산 발생 시 심각한 오버헤드가 발생한다. 본 논문은 이러한 오버헤드를 줄이기 위해 새롭게 고안된 스트라이드 스킵 리스트(Stride Skip List)를 제안한다. 스트라이드 스킵 리스트는 동일 키의 마지막 노드에 대한 인덱싱 포인터를 추가적으로 유지하여 불필요한 노드 방문을 피할 수 있도록 한다. 제안된 기법은 RocksDB의 인메모리 컴포넌트를 활용하여 구현되었으며 다양한 워크로드에서 SCAN 연산의 성능을 기존 스킵 리스트 대비 최대 350배까지 향상시켰다.

바이오피드백을 이용한 심부목굽힘근운동이 목 질환에 미치는 영향: 메타분석 (Effects of Biofeedback Based Deep Neck Flexion Exercise on Neck Pain: Meta-analysis)

  • 박주희;전혜선;김지현;김예진;문경아;임원빈
    • 한국전문물리치료학회지
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    • 제28권1호
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    • pp.18-26
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    • 2021
  • Previous studies have reported that deep neck flexor (DNF) exercise can improve neck problems, including neck pain, forward head posture, and headache, by targeting the deep and superficial muscles of the neck. Despite the prevailing opinion across studies, the benefits of DNF can vary according to the type of neck problems and the outcome measures adopted, ranging from positive outcomes to non-significant benefits. A meta-analysis was conducted in this study to assess conclusive evidence of the impact of DNF exercise on individuals with neck problems. We used PUBMED, MEDLINE, NDSL, EMBASE, and Web of Science to search for primary studies and the key terms used in these searches were "forward head posture (FHP)," "biofeedback," "pressure biofeedback unit," "stabilizer," "headache," and "neck pain." Twenty-four eligible studies were included in this meta-analysis and were coded according to the type of neck problems and outcome measures described, such as pain, endurance, involvement of neck muscle, craniovertebral angle (CVA), neck disability index (NDI), cervical range of motion (CROM), radiographs of the neck, posture, strength, endurance, and headache disability index. The overall effect size of the DNF exercise was 0.489. The effect sizes of the neck problems were 0.556 (neck pain), -1.278 (FHP), 0.176 (headache), and 1.850 (mix). The effect sizes of outcome measures were 1.045 (pain), 0.966 (endurance), 0.894 (deep neck flexor), 0.608 (superficial neck flexor), 0.487 (CVA), 0.409 (NDI), and 0.252 (CROM). According to the results of this study, DNF exercise can effectively reduce neck pain. Thus, DNF exercise is highly recommend as an effective exercise method for individuals suffering from neck pain.

Influence of the root canal filling technique on the success rate of primary endodontic treatments: a systematic review

  • Daniel Feijolo Marconi ;Giovana Siocheta da Silva ;Theodoro Weissheimer;Isadora Ames Silva ;Gabriel Barcelos So;Leonardo Thomasi Jahnke ;Jovito Adiel Skupien ; Marcus Vinicius Reis So ; Ricardo Abreu da Rosa
    • Restorative Dentistry and Endodontics
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    • 제47권4호
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    • pp.40.1-40.18
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    • 2022
  • Objectives: This study aimed to investigate the influence of different obturation techniques compared to cold lateral compaction on the success rate of primary non-surgical endodontic treatments. Materials and Methods: Systematic searches were performed for studies published up to May 17th, 2022 in MEDLINE/PubMed, Cochrane Library, Web of Science, Scopus, EMBASE, and Grey Literature Reports. Randomized clinical trials and nonrandomized (nonrandomized clinical trials, prospective or retrospective) studies that evaluated the success rate of primary non-surgical endodontic treatments obturated with the cold lateral compaction (control) and other obturation techniques were included. The revised Cochrane risk of bias tools for randomized trials (RoB 2) and nonrandomized studies of interventions (ROBINS-I) were used to evaluate the risk of bias. The Grading of Recommendations Assessment, Development, and Evaluation (GRADE) tool was used to evaluate the certainty of evidence. Results: Eleven studies (4 randomized clinical trials (RCTs), 4 prospective, and 3 retrospectives) were included. Two RCTs were classified as having some concerns risk of bias and 2 as a low risk of bias. Two nonrandomized studies were classified as having a critical risk of bias and 5 as having a moderate risk of bias. The GRADE analysis demonstrated a very low to moderate certainty of evidence. Conclusions: This systematic review generally evidenced no differences in the success rate of primary non-surgical endodontic treatments when the cold lateral compaction technique and other obturation techniques are performed. Further well-designed studies are still necessary.

스마트 TV 환경에서 정보 검색을 위한 사용자 프로파일 기반 필터링 방법 (A User Profile-based Filtering Method for Information Search in Smart TV Environment)

  • 신위살;오경진;조근식
    • 지능정보연구
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    • 제18권3호
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    • pp.97-117
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    • 2012
  • 인터넷 사용자는 비디오를 보면서 소셜 네트워크 서비스를 이용하고 웹 검색을 하고, 비디오에 나타난 상품에 관심이 있을 경우 검색엔진을 통해 정보를 찾는다. 비디오와 사용자의 직접적인 상호작용을 위해 비디오 어노테이션에 대한 연구가 진행되었고, 스마트 TV 환경에서 어노테이션 된 비디오가 활용될 경우 사용자는 객체에 대한 링크를 통해 원하는 상품의 정보를 쉽게 확인할 수 있게 된다. 사용자가 상품에 대한 구매를 원할 경우 상품에 대한 정보검색 이외에 상품평이나 소셜 네트워크 친구의 의견을 통해 구매 결정을 한다. 소셜 네트워크로부터 발생되는 정보는 다른 정보에 비해 신뢰도가 높아 구매 결정에 큰 영향을 미친다. 하지만 현재 소셜 네트워크 서비스는 의견을 얻고자 할 경우 모든 소셜 네트워크 친구들에게 전달되고 많은 의견을 얻게 되어 이들로부터 유용한 정보를 파악하는 것은 쉽지 않다. 본 논문에서는 소셜 네트워크 사용자의 프로파일을 기반으로 상품에 대해 유용한 정보를 제공할 수 있는 친구를 규명하기 위한 필터링 방법을 제안한다. 사용자 프로파일은 페이스북의 사용자 정보와 페이스북 페이지의 'Like' 정보를 이용하여 구성된다. 프로파일의 상품 정보는 GoodRelations 온톨로지와 BestBuy 데이터를 이용하여 의미적으로 표현된다. 사용자가 비디오를 보면서 상품 정보를 얻고자 할 경우 어노테이션된 URI를 이용하여 정보가 전달된다. 시스템은 소셜 네트워크 친구들에 대한 사용자 프로파일과 BestBuy를 기반으로 어노테이션된 상품에 대한 의미적 유사도를 계산하고 유사도 값에 따라 순위가 결정한다. 결정된 순위는 유용한 정보를 제공할 수 있는 소셜 네트워크 상의 친구를 규명하는데 사용된다. 참가자의 동의하에 페이스북 정보를 활용하였고, 시스템에 의해 도출된 결과와 참가자 인터뷰를 통해 평가된 결과를 이용하여 타당성을 검증하였다. 비교 실험의 결과는 제안하는 시스템이 상품 구매결정을 하기 위해 유용한 정보를 획득할 수 있는 방법임을 증명한다.

네트노그라피를 이용한 공개 소프트웨어의 개발 및 확산 패턴 분석에 관한 연구 - 자바스크립트 프레임워크 사례를 중심으로 - (Tracing the Development and Spread Patterns of OSS using the Method of Netnography - The Case of JavaScript Frameworks -)

  • 강희숙;윤인환;이희상
    • 경영과정보연구
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    • 제36권3호
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    • pp.131-150
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    • 2017
  • 본 연구의 목적은 공개 소프트웨어(Open Source Software, 이하 OSS)가 운영 기간 내 주변의 행위자들과 관계를 수립하는 동안 OSS의 개발 및 확산 패턴을 확인하는 것으로, OSS 참여자들의 변화 패턴을 조사하기 위해 OSS 통과시간을 기반으로 그 변화 양상을 추적할 수 있는 온라인 데이터와 네트노그라피 방법을 이용하였다. 이를 위해 대표적인 OSS 자바스크립트 프레임워크인 jQuery, MooTools, YUI 등 이상 세 가지 사례에 대하여 블로그, 웹 서치와 함께 GitHub 공개 API(Application Programming Interface)로 수집된 데이터를 활용하였다. 본 연구에서는 OSS 변형 과정의 변화 패턴을 분류하기 위하여 행위자-네트워크 이론의 전환(translation) 과정을 적용하였으며, 관찰된 OSS 변형 과정을 살펴보면 다음과 같다. 먼저, '프로젝트 개시' 단계에서 소스 코드, 프로젝트 책임자 및 관계자, 내부 참여자 등과 같은 세 가지 유형의 OSS 관련 행위자들을 확인하였고, 그들 사이의 관계성을 개념화 하였다. 이후 프로젝트 책임자가 최초로 프로젝트를 착수하는 '프로젝트 성장' 단계는 관계자들에 의해 소스 코드가 유지 보수되는 과정을 통해 개선된다. 마지막으로 OSS는 홍보 활동을 통해 참여자들의 관찰기를 갖고, 소스 코드 사용을 통해 학습기를 거친 사용자가 본격적으로 등장함으로써 '참여자의 도약' 단계로 진입한다. 이 시기에는 기업과 외부 관계자들도 출현하는 모습도 살펴볼 수 있다. 본 연구결과는 OSS 참여자들이 OSS를 선택하는데 있어 홍보 과정의 중요성을 강조하고, OSS의 급속한 개발속도가 오히려 참여자의 출현을 지연시키는 구축 효과(crowding-out effec)가 발생하는 것을 확인하였다. 본 연구는 행위자-네트워크 이론을 토대로 주요 OSS 사례를 네트노그라피를 활용하여 종단적인 관점에서 분석함으로써 OSS의 발전 과정을 일반화시키기 위한 노력을 시도했다는 점에서 학술적인 의의가 있으며, OSS가 지배적인 위치에 오르기 위한 단계별 영향 요인, 세부적인 변화 양상 등을 확인함으로써 OSS 개발자와 관리자들에게 다양한 시사점을 제공할 것으로 기대된다.

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A Study on the Meaning and Strategy of Keyword Advertising Marketing

  • Park, Nam Goo
    • 유통과학연구
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    • 제8권3호
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    • pp.49-56
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    • 2010
  • At the initial stage of Internet advertising, banner advertising came into fashion. As the Internet developed into a central part of daily lives and the competition in the on-line advertising market was getting fierce, there was not enough space for banner advertising, which rushed to portal sites only. All these factors was responsible for an upsurge in advertising prices. Consequently, the high-cost and low-efficiency problems with banner advertising were raised, which led to an emergence of keyword advertising as a new type of Internet advertising to replace its predecessor. In the beginning of 2000s, when Internet advertising came to be activated, display advertisement including banner advertising dominated the Net. However, display advertising showed signs of gradual decline, and registered minus growth in the year 2009, whereas keyword advertising showed rapid growth and started to outdo display advertising as of the year 2005. Keyword advertising refers to the advertising technique that exposes relevant advertisements on the top of research sites when one searches for a keyword. Instead of exposing advertisements to unspecified individuals like banner advertising, keyword advertising, or targeted advertising technique, shows advertisements only when customers search for a desired keyword so that only highly prospective customers are given a chance to see them. In this context, it is also referred to as search advertising. It is regarded as more aggressive advertising with a high hit rate than previous advertising in that, instead of the seller discovering customers and running an advertisement for them like TV, radios or banner advertising, it exposes advertisements to visiting customers. Keyword advertising makes it possible for a company to seek publicity on line simply by making use of a single word and to achieve a maximum of efficiency at a minimum cost. The strong point of keyword advertising is that customers are allowed to directly contact the products in question through its more efficient advertising when compared to the advertisements of mass media such as TV and radio, etc. The weak point of keyword advertising is that a company should have its advertisement registered on each and every portal site and finds it hard to exercise substantial supervision over its advertisement, there being a possibility of its advertising expenses exceeding its profits. Keyword advertising severs as the most appropriate methods of advertising for the sales and publicity of small and medium enterprises which are in need of a maximum of advertising effect at a low advertising cost. At present, keyword advertising is divided into CPC advertising and CPM advertising. The former is known as the most efficient technique, which is also referred to as advertising based on the meter rate system; A company is supposed to pay for the number of clicks on a searched keyword which users have searched. This is representatively adopted by Overture, Google's Adwords, Naver's Clickchoice, and Daum's Clicks, etc. CPM advertising is dependent upon the flat rate payment system, making a company pay for its advertisement on the basis of the number of exposure, not on the basis of the number of clicks. This method fixes a price for advertisement on the basis of 1,000-time exposure, and is mainly adopted by Naver's Timechoice, Daum's Speciallink, and Nate's Speedup, etc, At present, the CPC method is most frequently adopted. The weak point of the CPC method is that advertising cost can rise through constant clicks from the same IP. If a company makes good use of strategies for maximizing the strong points of keyword advertising and complementing its weak points, it is highly likely to turn its visitors into prospective customers. Accordingly, an advertiser should make an analysis of customers' behavior and approach them in a variety of ways, trying hard to find out what they want. With this in mind, her or she has to put multiple keywords into use when running for ads. When he or she first runs an ad, he or she should first give priority to which keyword to select. The advertiser should consider how many individuals using a search engine will click the keyword in question and how much money he or she has to pay for the advertisement. As the popular keywords that the users of search engines are frequently using are expensive in terms of a unit cost per click, the advertisers without much money for advertising at the initial phrase should pay attention to detailed keywords suitable to their budget. Detailed keywords are also referred to as peripheral keywords or extension keywords, which can be called a combination of major keywords. Most keywords are in the form of texts. The biggest strong point of text-based advertising is that it looks like search results, causing little antipathy to it. But it fails to attract much attention because of the fact that most keyword advertising is in the form of texts. Image-embedded advertising is easy to notice due to images, but it is exposed on the lower part of a web page and regarded as an advertisement, which leads to a low click through rate. However, its strong point is that its prices are lower than those of text-based advertising. If a company owns a logo or a product that is easy enough for people to recognize, the company is well advised to make good use of image-embedded advertising so as to attract Internet users' attention. Advertisers should make an analysis of their logos and examine customers' responses based on the events of sites in question and the composition of products as a vehicle for monitoring their behavior in detail. Besides, keyword advertising allows them to analyze the advertising effects of exposed keywords through the analysis of logos. The logo analysis refers to a close analysis of the current situation of a site by making an analysis of information about visitors on the basis of the analysis of the number of visitors and page view, and that of cookie values. It is in the log files generated through each Web server that a user's IP, used pages, the time when he or she uses it, and cookie values are stored. The log files contain a huge amount of data. As it is almost impossible to make a direct analysis of these log files, one is supposed to make an analysis of them by using solutions for a log analysis. The generic information that can be extracted from tools for each logo analysis includes the number of viewing the total pages, the number of average page view per day, the number of basic page view, the number of page view per visit, the total number of hits, the number of average hits per day, the number of hits per visit, the number of visits, the number of average visits per day, the net number of visitors, average visitors per day, one-time visitors, visitors who have come more than twice, and average using hours, etc. These sites are deemed to be useful for utilizing data for the analysis of the situation and current status of rival companies as well as benchmarking. As keyword advertising exposes advertisements exclusively on search-result pages, competition among advertisers attempting to preoccupy popular keywords is very fierce. Some portal sites keep on giving priority to the existing advertisers, whereas others provide chances to purchase keywords in question to all the advertisers after the advertising contract is over. If an advertiser tries to rely on keywords sensitive to seasons and timeliness in case of sites providing priority to the established advertisers, he or she may as well make a purchase of a vacant place for advertising lest he or she should miss appropriate timing for advertising. However, Naver doesn't provide priority to the existing advertisers as far as all the keyword advertisements are concerned. In this case, one can preoccupy keywords if he or she enters into a contract after confirming the contract period for advertising. This study is designed to take a look at marketing for keyword advertising and to present effective strategies for keyword advertising marketing. At present, the Korean CPC advertising market is virtually monopolized by Overture. Its strong points are that Overture is based on the CPC charging model and that advertisements are registered on the top of the most representative portal sites in Korea. These advantages serve as the most appropriate medium for small and medium enterprises to use. However, the CPC method of Overture has its weak points, too. That is, the CPC method is not the only perfect advertising model among the search advertisements in the on-line market. So it is absolutely necessary that small and medium enterprises including independent shopping malls should complement the weaknesses of the CPC method and make good use of strategies for maximizing its strengths so as to increase their sales and to create a point of contact with customers.

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