• Journal of Korean Society of Industrial and Systems Engineering
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• v.44 no.1
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• pp.26-36
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• 2021

The topic of this study is the field of humanitarian logistics for disaster response. Many existing studies have revealed that compliance with the golden time in response to a disaster determines the success or failure of relief activities, and logistics costs account for 80% of the disaster response cost. Besides, the agility, responsiveness, and effectiveness of the humanitarian logistics system are emphasized in consideration of the disaster situation's characteristics, such as the urgency of life-saving and rapid environmental changes. In other words, they emphasize the importance of logistics activities in disaster response, which includes the effective and efficient distribution of relief supplies. This study proposes a mathematical model for establishing a transport plan to distribute relief supplies in a disaster situation. To determine vehicles' route and the amount of relief for cities suffering a disaster, it mainly considers the urgency, effectiveness (restoration rate), and uncertainty in the logistics system. The model is initially developed as a mixed-integer nonlinear programming (MINLP) model containing some nonlinear functions and transform into a Mixed-integer linear programming (MILP) model using a logarithmic transformation and piecewise linear approximation method. Furthermore, a minimax problem is suggested to search for breakpoints and slopes to define a piecewise linear function that minimizes the linear approximation error. A numerical experiment is performed to verify the MILP model, and linear approximation error is also analyzed in the experiment.

• Journal of Korea Society of Industrial Information Systems
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• v.28 no.6
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• pp.99-105
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• 2023

Submarines, which require a high degree of survivability, are among the most critical combat weapon systems in military strategic assets. Conventional submarines need air to operate their propulsion systems. Exhaust gases released into the water during snorkel navigation heat the surrounding fluid, producing a temperature wake. This wake, in turn, reduces the submarine's survivability. In this study, we conducted a preliminary experiment on the temperature traces formed by an underwater submarine's waste discharge. For this purpose, we collected propulsion system and navigation condition data from domestically introduced submarines and developed an experimental system to measure the temperature traces. As a result, we observed that high-temperature bubbles injected into the tank broke down into smaller sizes, and their temperature dropped to levels similar to the surrounding fluid. This observation was confirmed using a thermocouple sensor. Consequently, the thermal imaging system designed to measure the temperature trace of the water's surface did not detect any significant temperature traces.

• The Journal of the Korea institute of electronic communication sciences
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• v.18 no.6
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• pp.1125-1132
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• 2023

The importance of networks is gradually expanding in the battlefield environment. As time goes by, the types of tactical data links used in the Korean JTDLS are increasing, and the military's weapon systems equipped with tactical data link systems are increasing. Thorough quality verification is required to provide stable software to the wider battlefield. This study examines how to prepare an environment in which various simulation tests to verify the stability of the Korean JTDLS project can be conducted as diverse as possible using minimal physical space and Hardware resources. Through this, it is possible to improve the completeness of the project and secure the stability of the program, and it is intended to contribute to securing higher stability and reliability by securing maximum test capabilities in a limited test environment even in Linux based system project of a similar environment.

• Development and Reproduction
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• v.17 no.4
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• pp.321-327
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• 2013

The innate immune system is the only defense weapon that invertebrates have, and it is the fundamental defense mechanism for fish. The innate immune response is important in newly hatched flounders because it is closely involved in the initial feeding phase, which is why it is essential for survival during the juvenile period. The expression analysis of genes involved in the innate immune response in the olive flounder (Paralichthys olivaceus) in the days after hatching is incomplete. Therefore, we have begun to examine the expression patterns of genes specifically induced during the development of the innate immune system in newly hatched flounders. Microscopic observation showed that pronephron formation corresponded with the expression of perforin-encoding gene. These results suggest that perforin plays a vital role in the innate immunity of the kidney during developmental stages. Perforin expression was strong at the start of the development of the innate immune response, and continued throughout all the development stages. Our findings have important implications with respect to perforin's biological role and the evolution of the first defense mechanisms in olive flounder. Further studies are required to elucidate the perforin-mediated innate immunity response and to decipher the functional role of perforin in developmental stages.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.6
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• pp.70-77
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• 2020

Configuration management is an important project management method. Configuration management is increasing daily and improving defense power as a management tool for technical data of power support systems. Configuration management work must be carried out properly from the beginning of development to acquire an excellent weapon system. In procurement, configuration management is a vital factor that can determine the cost of maintaining operations during the transfer of military supplies and carry out systematic management among operational support. Countries are making changes to policies and systems to manage R&D, standards, and patents in conjunction with each other from the beginning of research and execution, and it is important to establish the concept of managing and controlling the configuration as an efficient means of managing military resources. To identify the activity details during the entire life cycle from the beginning of acquisition to the end of disposal by linking munitions configuration control with the total life cycle, and redefine the appropriate work system, this study investigated and analyzed the U.S. configuration control procedures to identify the activity details and present areas to develop.

• The Plant Pathology Journal
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• v.34 no.1
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• pp.11-22
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• 2018

Type VI secretion system (T6SS) has been discovered in a variety of gram-negative bacteria as a versatile weapon to stimulate the killing of eukaryotic cells or prokaryotic competitors. Type VI secretion effectors (T6SEs) are well known as key virulence factors for important pathogenic bacteria. In many Burkholderia species, T6SS has evolved as the most complicated secretion pathway with distinguished types to translocate diverse T6SEs, suggesting their essential roles in this genus. Here we attempted to detect and characterize T6SSs and potential T6SEs in target genomes of plant-associated and environmental Burkholderia species based on computational analyses. In total, 66 potential functional T6SS clusters were found in 30 target Burkholderia bacterial genomes, of which 33% possess three or four clusters. The core proteins in each cluster were specified and phylogenetic trees of three components (i.e., TssC, TssD, TssL) were constructed to elucidate the relationship among the identified T6SS clusters. Next, we identified 322 potential T6SEs in the target genomes based on homology searches and explored the important domains conserved in effector candidates. In addition, using the screening approach based on the profile hidden Markov model (pHMM) of T6SEs that possess markers for type VI effectors (MIX motif) (MIX T6SEs), 57 revealed proteins that were not included in training datasets were recognized as novel MIX T6SE candidates from the Burkholderia species. This approach could be useful to identify potential T6SEs from other bacterial genomes.

• Journal of Microbiology and Biotechnology
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• v.26 no.3
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• pp.596-602
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• 2016

Staphylococcus aureus, like other gram-positive pathogens, has evolved a large repertoire of virulence factors as a powerful weapon to subvert the host immune system, among which alpha-hemolysin (Hla), a secreted pore-forming cytotoxin, plays a preeminent role. We observed a concentration-dependent reduction in Hla production by S. aureus in the presence of sub-inhibitory concentrations of isorhamnetin, a flavonoid from the fruits of Hippophae rhamnoides L., which has little antibacterial activity. We further evaluate the effect of isorhamnetin on the transcription of the Hla-encoding gene hla and RNAIII, an effector molecule in the agr system. Isorhamnetin significantly down-regulated RNAIII expression and subsequently inhibited hla transcription. In a co-culture of S. aureus and lung cells, topical isorhamnetin treatment protected against S. aureus-induced cell injury. Isorhamnetin may represent a leading compound for the development of anti-virulence drugs against S. aureus infections.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.40 no.1
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• pp.11-21
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• 2017

Artillery fire power due to effectiveness which is hard to predict well-planned and surprising attack can give a fear and shock to the personnel and is a very core weapon system and takes a critical role in wartime. Therefore in order to maximize operational effectiveness, Army required protecting artillery and takes a quick attack action through rapid construction of artillery's positions. The artillery use artillery's position to prevent exposure by moving to other position frequently. They have to move and construct at new artillery's positions quickly against exposing existed place by foe's recognition. These positions should be built by not manpower but engineering construction equipment. Because artillery positions have to protect human and artillery equipment well and build quickly. Military engineering battalion have lots of construction equipment which include excavator, loader, dozer, combat multi-purposed excavator, armored combat earthmover dump truck and so on. So they have to decide to optimal number of Team combining these equipments and determine construction sequence of artillery's position in operational plan. In this research, we propose to decide number of Team efficiently and allocate required construction's positions for each Team under constraints of limited equipments and time. To do so, we develop efficient heuristic method which can give near optimal solution and be applied to various situation including commander's intention, artillery position's priority or grouping etc. This heuristic can support quick and flexible construction plan of artillery positions not only for using various composition's equipment to organize Teams but also for changing quantity of positions.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.42 no.4
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• pp.203-210
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• 2019

Recently, a number of researchers have produced research and reports in order to forecast more exactly air quality such as particulate matter and odor. However, such research mainly focuses on the atmospheric diffusion models that have been used for the air quality prediction in environmental engineering area. Even though it has various merits, it has some limitation in that it uses very limited spatial attributes such as geographical attributes. Thus, we propose the new approach to forecast an air quality using a deep learning based ensemble model combining temporal and spatial predictor. The temporal predictor employs the RNN LSTM and the spatial predictor is based on the geographically weighted regression model. The ensemble model also uses the RNN LSTM that combines two models with stacking structure. The ensemble model is capable of inferring the air quality of the areas without air quality monitoring station, and even forecasting future air quality. We installed the IoT sensors measuring PM2.5, PM10, H2S, NH3, VOC at the 8 stations in Jeonju in order to gather air quality data. The numerical results showed that our new model has very exact prediction capability with comparison to the real measured data. It implies that the spatial attributes should be considered to more exact air quality prediction.

• Journal of the Korea Safety Management & Science
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• v.17 no.1
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• pp.93-101
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• 2015

The demand from customers on better products and systems seems to be ever increasing. To meet the demand, the systems are becoming more and more complicated in terms of both scale and functionality, thereby requiring enormous effort in the development. One bright spot of this trend is that such effort has been the driving forces of the remarkable advancement in modern systems development. On the other hand, safety issues appear to be critical in many large-scale systems such as transportation and weapon systems including high-speed trains, airplanes, ships, missiles/rockets launchers, and so on. Such systems turn out to be prone to a variety of faults and thus the resultant failure can cause disastrous accidents. For the reason, they can be referred to as safety-critical systems. The systems failure can be attributed to either random or systemic factors (or sometimes both). The objective of this paper is on how to reduce potential systemic failure in safety critical systems. To do so, a proper system design is pursued to minimize the risk of systemic failure. A focus is placed on the fact that complex systems have a lot of complicated interfaces among the system elements. To effectively handle the sources of hazards at the complicated interfaces and resultant failure, a method is developed by utilizing a design structure matrix. As a case study, the developed method is applied in the design of train control systems.