• 제목/요약/키워드: Weak D testing

검색결과 26건 처리시간 0.027초

Weak D Testing is not Required for D- Patients With C-E- Phenotype

  • Choi, Sooin;Chun, Sejong;Lee, Hwan Tae;Yu, HongBi;Seo, Ji Young;Cho, Duck
    • Annals of Laboratory Medicine
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    • 제38권6호
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    • pp.585-590
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    • 2018
  • Background: Although testing to detect weak D antigens using the antihuman globulin reagent is not required for D- patients in many countries, it is routinely performed in Korea. However, weak D testing can be omitted in D- patients with a C-E- phenotype as this indicates complete deletion of the RHD gene, except in rare cases. We designed a new algorithm for weak D testing, which consisted of RhCE phenotyping followed by weak D testing in C+ or E+ samples, and compared it with the current algorithm with respect to time and cost-effectiveness. Methods: In this retrospective study, 74,889 test results from January to July 2017 in a tertiary hospital in Korea were analyzed. Agreement between the current and proposed algorithms was evaluated, and total number of tests, time required for testing, and test costs were compared. With both algorithms, RHD genotyping was conducted for samples that were C+ or E+ and negative for weak D testing. Results: The algorithms showed perfect agreement (agreement=100%; ${\kappa}=1.00$). By applying the proposed algorithm, 29.56% (115/389 tests/yr) of tests could be omitted, time required for testing could be reduced by 36% (8,672/24,084 min/yr), and the test cost could be reduced by 16.53% (536.11/3,241.08 USD/yr). Conclusions: Our algorithm omitting weak D testing in D- patients with C-E- phenotype may be a cost-effective testing strategy in Korea.

Cyclic testing of weak-axis steel moment connections

  • Lee, Kangmin;Li, Rui;Jung, Heetaek;Chen, Liuyi;Oh, Kyunghwan
    • Steel and Composite Structures
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    • 제15권5호
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    • pp.507-518
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    • 2013
  • The seismic performance of six types of weak-axis steel moment connections was investigated through cyclic testing of six full-scale specimens. These weak-axis moment connections were the column-tree type, WUF-B type, FF-W type, WFP type, BFP-B type and DST type weak-axis connections. The testing results showed that each of these weak-axis connection types achieved excellent seismic performance, except the WFP and the WUF-B types. The WFP and WUF-B connections displayed poor seismic performance because a fracture appeared prematurely at the weld joint due to stress concentrations. The column-tree type connection showed the best seismic behavior such that the story drift ratio could reach 5%.

Effect of particle size and saturation conditions on the breakage factor of weak rockfill materials under one-dimensional compression testing

  • Rahmani, Hamidreza;Panah, Ali Komak
    • Geomechanics and Engineering
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    • 제21권4호
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    • pp.315-326
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    • 2020
  • The long-term behavior of rockfill material used in the construction of infrastructures such as dams is of great significance. Because of concerns about the application of weak rockfill material in dam construction, further experimental studies on the behavior of these materials are required. In this study, laboratory experiments were performed to investigate the one-dimensional deformation and particle breakage of the weak rockfill material under stress. A one-dimensional compression apparatus was designed and developed for testing of rockfill materials of different maximum particle sizes (MPSs). The compression tests were performed under dry, wet and saturated conditions on samples of rockfill material obtained from a dam construction site in Iran. The results of the experiments conducted at the specimen preparation stage and the 1D compression tests are presented. In weak rockfill, the effect of the addition of water on the behavior of the material was uncertain as there were both an increases and decreases observed in particle breakage. Increasing the MPS of the weak rockfill materials increased particle breakage, which was similar to the behavior of strong rockfill material. In all of the MPSs examined, the settlement of specimens under wet conditions was higher than that observed under dry conditions. Also, the greatest deformation occurred during the first hour of loading.

A Two Sample Test for Functional Data

  • Lee, Jong Soo;Cox, Dennis D.;Follen, Michele
    • Communications for Statistical Applications and Methods
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    • 제22권2호
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    • pp.121-135
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    • 2015
  • We consider testing equality of mean functions from two samples of functional data. A novel test based on the adaptive Neyman methodology applied to the Hotelling's T-squared statistic is proposed. Under the enlarged null hypothesis that the distributions of the two populations are the same, randomization methods are proposed to find a null distribution which gives accurate significance levels. An extensive simulation study is presented which shows that the proposed test works very well in comparison with several other methods under a variety of alternatives and is one of the best methods for all alternatives, whereas the other methods all show weak power at some alternatives. An application to a real-world data set demonstrates the applicability of the method.

아산만 방조제 배수갑문 확장사업에 따른 주변해역 수리현상 변화 검토 (Estimation of Hydraulic States Caused by Gate Expansion in Asan Bay)

  • 박병준;이상화
    • 한국해안·해양공학회논문집
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    • 제20권2호
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    • pp.184-193
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    • 2008
  • 아산호 상류지역의 도시화 진행과 이상 기후 등에 따른 강수량 증가로 아산만 방조제 배수갑문 확장의 필요성이 제기됨에 따라 배수갑문 확장으로 인한 방류량 증가가 아산만 및 주변 해역에 미치는 영향을 수리모형실험과 범용 수치모의 코드인 Delft3D, FLOW-3D를 이용하여 검토하였다. 그 결과 아산만 방조제 배수갑문확장에 의한 영향은 미흡한 것으로 확인되었다.

지하매설 가스관의 검사를 위한 누설자속탐상 PIG 설계에 관한 연구 (Research on MFL PIG Design for the Inspection of Underground Gas Pipeline)

  • 박상호;박관수
    • 비파괴검사학회지
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    • 제22권2호
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    • pp.177-186
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    • 2002
  • 본 논문에서는 3차원 형태의 결함을 가진 지하매설 가스관에서 누설자속(magnetic flux leakage, MFL) 탐상 법을 사용한 결함 검출에 관하여 연구하였다. 영구자석과 요크로 구성된 자기 시스템을 유한요소법을 사용하여 해석하고 동작점을 설정하였다. 가스관이 충분히 포화되지 않은 경우에는 측정이 곤란하며, 과대포화 된 경우에는 결함에 의한 누설자속의 변화량이 적어서 측정이 곤란하므로 적정한 값을 설정하여야 하므로 자기 시스템의 동작점은 결함이 있을 때 누설자속 증가율이 최대가 되도록 설정하여야 한다. 본 논문에서는 3차원 비선형 유한요소법을 사용하여, 가스관에 결함이 있는 경우 결합의 크기, 깊이에 따른 결함신호를 예측하여 그 결과 가스관 포화상태의 적절여부, 홀 센서 range 및 resolution의 적정도 등을 연구하였다. 또한 홀 센서의 민감도 형장을 위하여 back-yoke를 사용하여 측정신호를 향상시키는 방법을 제안하였다.

The fractal analysis of the fracture surface of concretes made from different coarse aggregates

  • Prokopski, Grzegorz;Konkol, Janusz
    • Computers and Concrete
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    • 제2권3호
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    • pp.239-248
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    • 2005
  • The article presents the results of examination of the fractal dimension D of concrete specimen fracture surfaces obtained in fracture toughness tests. The concretes were made from three different types of coarse aggregate: gravel, dolomite and basalt aggregate. Ordinary concretes (C40) and high-performance concretes (HPC) were subjected to testing after 7, 14, 28 and 90 days of curing, respectively. In fracture toughness and compressive tests, different behaviours of concretes were found, depending on the type of aggregate and class of concrete (C40, HPC). A significant increase in the strength parameters tested occurred also after a period of 28 days (up to the $90^{th}$ day of curing) and was particularly large for concretes C40. Fractal examinations performed on fracture replicas showed that the fractal dimension D was diverse, depending on the coarse aggregate type and concrete class being, however, statistically constant after 7 and 14 days for respective concretes during curing. The fractal dimension D was the greater, the worse strength properties were possessed by the concrete. A cross-grain crack propagation occurred in that case, due to weak cohesion forces at the coarse aggregate/mortar interface. A similar effect was observed for C40 and HPC made from the same aggregate. A greater dimension D was exhibited by concretes C40, in which case the fracture was easier to form compared with high-performance concretes, where, as a result of high aggregate/mortar cohesion forces, the crack propagation was of inter-granular type, and the resulted fracture was flatter.

미소신호 검출과 추정에 관한 알고리즘 (The Algorithm for Weak Signal Detection and Estimation)

  • 신승호;진용옥
    • 한국통신학회논문지
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    • 제11권5호
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    • pp.349-359
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    • 1986
  • 본 연구는 3~7MHz 사이의 단파대역에서 200Hz이하의 대역폭을 가지며 출현빈도가 극히 낮은 신호를 자동 식별하기 위한 기본 연구이다. 이를 위하여 1차적으로 100KHz대역에서 0dB정도의 OOK신호에 대하여 그 존재유무를 판단하는 검출과 추정 방법에 대하여 기수한 것이다. 검출과 추정 과정에서 OOK변조 신호에 잡음이 혼입되어 오염된 상태에서 LOD와 E-C는 약 77%를 상관함수 패턴모형 방법은 약90%를 올바르게 판정하였다.

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Eigenspace-based MLLR에 기반한 고속 화자적응 및 환경보상 (Fast Speaker Adaptation and Environment Compensation Based on Eigenspace-based MLLR)

  • 송화전;김형순
    • 대한음성학회지:말소리
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    • 제58호
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    • pp.35-44
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    • 2006
  • Maximum likelihood linear regression (MLLR) adaptation experiences severe performance degradation with very tiny amount of adaptation data. Eigenspace- based MLLR, as an alternative to MLLR for fast speaker adaptation, also has a weak point that it cannot deal with the mismatch between training and testing environments. In this paper, we propose a simultaneous fast speaker and environment adaptation based on eigenspace-based MLLR. We also extend the sub-stream based eigenspace-based MLLR to generalize the eigenspace-based MLLR with bias compensation. A vocabulary-independent word recognition experiment shows the proposed algorithm is superior to eigenspace-based MLLR regardless of the amount of adaptation data in diverse noisy environments. Especially, proposed sub-stream eigenspace-based MLLR with bias compensation yields 67% relative improvement with 10 adaptation words in 10 dB SNR environment, in comparison with the conventional eigenspace-based MLLR.

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FDM 3D프린팅 어닐링 조건에 따른 내부응력 완화에 관한 연구 (Investigation of the Internal Stress Relaxation in FDM 3D Printing : Annealing Conditions)

  • 이선곤;김용래;김수현;김주형
    • 한국기계가공학회지
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    • 제17권4호
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    • pp.130-136
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    • 2018
  • In this paper, the effects of different 3D printing parameters including laminated angle and annealing temperature, were observed for their effects on tensile testing. In 3D printing, a filament is heated quickly, extruded, and then cooled rapidly. Because plastic is a poor heat conductor, it heats and cools unevenly causing the rapid heating and cooling to create internal stress within the printed part. Therefore, internal stress can be removed using annealing and to increase tensile strength and strain. During air cooling at annealing temperature $140^{\circ}C$, the strain of laminated angle $45^{\circ}$ specimens tended to increase by 46% while the tensile stress tended to increase by 7.4%. During oven cooling at annealing temperature $140^{\circ}C$, the strain of laminated angle $45^{\circ}$ specimens tended to increase by 34% while the tensile stress tended to increase by 22.2%. In this study, we found "3D printing with annealing" eliminates internal stress and increases the strength and stiffness of a printed piece. On the microstructural level, annealing reforms the crystalline structures to even out the areas of high and low stress, which created fewer weak areas. These results are very useful for making 3D printed products with a mechanical strength that is suitable for applications.