• Proceedings of the PSK Conference
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• 2002.10a
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• pp.263.2-264
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• 2002

SPH-l is a herbal medicine composing oriental prescription. We have studied the antidiabetic effect and mechanism of SPH-l in insulin-resistant diabetic db/db mice. Mice were grouped and treated for 3 weeks as follows: control group was administrated with tap water orally: treated group was administrated with SPH-l orally at dose of 500 mg/kg. SPH-l lowered plasma glucose level by 67% as compared to the diabetic control (omitted)

• Proceedings of the PSK Conference
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• 2002.10a
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• pp.260.2-260.2
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• 2002

SPH-2 is a herbal medicine composing oriental prescription. We have studied the antidiabetic effect and mechanism of SPH-2 in insulin-resistant diabetic db/db mice. Mice were grouped and treated for 3 weeks as follows: control group was administrated with tap water orally: treated group was administrated with SPH-2 orally at dose of 500 mg/kg. SPH-2 lowered plasma glucose level by 43% as compared to the diabetic control. Total cholesterol. triglyceride and free fatty acid were all reduced in SPH-2 treated group. (omitted)

• Journal of Nutrition and Health
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• v.49 no.6
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• pp.401-410
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• 2016

Purpose: Water is magnetically charged upon contact with a magnet. Although magnetic water products have been promoted since the 1930's, they have not received wide acceptance since their effectiveness is still in question; however, some have reported their therapeutic effects on the body, especially the digestive, nervous, and urinary systems. Methods: In this study, the effect of magnetized water on glycemic control of 14 diabetic mice (CB57BK/KsJ-db/db) in comparison with 10 control mice (CB57BK/KsJ-db/+(db/+)) was investigated. Seven diabetic control (DMC) mice and seven diabetic mice + magnetized water (DM+MW) were kept for 16 weeks, followed by intraperitoneal glucose tolerance test (IPGTT). Weekly blood glucose was measured from tail veins. Blood obtained from heart puncture was used for HbA1c analysis. Results: Blood glucose level showed a significant difference starting from the $10^{th}$ week of study ($496.1{\pm}10.2mg/dl$ in DMC vs. $437.9{\pm}76.9mg/dl$ in DM+MW). Blood glucose followed by IPGTT showed no significant difference between groups at 0, 30, 60, 90, and 120 min, although glucose level at 180 min was significantly reduced in DM+MW mice. Plasma insulin level in DM+MW groups was only 39.5% of that of DMC groups ($5.97{\pm}1.69ng/ml$ in DMC vs. $2.36{\pm}0.94ng/ml$ in DM+MW). Levels of HbA1c were 12.4% and 9.7% in DMC and DM+MW groups, respectively. Conclusion: These results show the promising therapeutic effect of magnetized water in regulating blood glucose homeostasis; however, long-term supplementation or mechanistic study is necessary.

• Food Science and Biotechnology
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• v.18 no.2
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• pp.323-329
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• 2009

The prescriptions (DB-1-DB-5) were prepared with the active herbal medicines, Acanthopanax senticosus, Glycyrrhiza uralensis, Polygonatum odoratum, and Cichorium intybus. The most active crude polysaccharide fraction (DB-2-3), which was isolated through the fractionation of hot-water extract from DB-2, was significantly reduced by periodate oxidation (52.7 and 63.7%) on intestinal immune system modulating and anticancer activity. When DB-2-3 was further fractionated by column chromatographies, DB-2-3IIc-2 showed the most potent activities. In addition, DB-2-3IIc stimulated the proliferation of bone marrow cells via Peyer's patch in dose-dependent pattern by oral administration. The metastasis of colon 26-M3.1 lung carcinoma had significantly inhibited in mice fed DB-2-3IIc at 1 mg/mouse (43.8%). DB-2-3IIc-2 mainly contained uronic acid (46.1%) and 42.5% of neutral sugar with a small amount of protein (7.6%), and component sugar analysis also showed that DB-2-3IIc-2 was composed Ara, Gal, and GalA (molar ratio; 0.50:0.63:1.00). It may be suggested that activities of DB-2-3IIc-2 are resulted from pectic polysaccharides containing a polygalacturonan moiety with side chain of neutral sugars, such as Ara and Gal.

• Journal of Korean Society for Geospatial Information Science
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• v.12 no.3 s.30
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• pp.69-78
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• 2004

Since 1995, One of the NGIS(National Geographic Information System) projects, the underground utilities project, has been finished in 2003. The 19 cities in korea for this project will use underground utilities management system using underground utilities database focusing on water and sewage system. However, special expert, technical and experience problem in computer environment has not been had in working department for water and sewage management and maintenance for each local government. The management and maintenance by underground utilities database by manual method is getting lowered a data qualify of underground utilities database because of the data omitting, error in writing and securing of the lasted database. Therefore, in this study, Application test for field workers using a mobile tool and environment analysis of wireless communication in Korea and application test of GPS receiver for mobile tools had been processed and made a mobile working environment. The efficient management and maintenance method for underground utilities database has been developed an off-line method for modification and update of database about general work which has a high working frequency because of the limitation of wireless communication environment. Also, the emergency working has been applied for on-line method.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2001.11a
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• pp.52-56
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• 2001

Experiments of 2 type on insulating compounds accomplished to change PVC using in URD(Underground) power cable jacketing. one was DB(Dielectric Breakdown) test on the pure base resins and the others were WVT(Water Vapor Transmission) test on the compounds which contained C/B(Carbon Black), anti-oxidant to base resin. a kind of specimens made by pressing to resin of pellet or lump form was HDPE(High Density Polyethylene), MDPE(Medium Density Polyehylene), LDPE(Low Density Polyethylene), LLDPE(Linear Low Density Polyethylene), PVC(Polyvinyl Chloride). As a results of AC DB and WVT test, we saw that strength of Insulation was HDPE> LLDPE = MDP E> LDPE and WVT ratio was HDPE

• Korean Journal of Remote Sensing
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• v.39 no.4
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• pp.425-440
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• 2023

Monitoring water surface has become one of the most prominent areas of research in addressing environmental challenges.Accurate and automated detection of watersurface in remote sensing imagesis crucial for disaster prevention, urban planning, and water resource management, particularly for a country where water plays a vital role in human life. However, achieving precise detection poses challenges. Previous studies have explored different approaches,such as analyzing water indexes, like normalized difference water index (NDWI) derived from satellite imagery's visible or infrared bands and using k-means clustering analysis to identify land cover patterns and segment regions based on similar attributes. Nonetheless, challenges persist, notably distinguishing between waterspectralsignatures and cloud shadow or terrain shadow. In thisstudy, our objective is to enhance the precision of water surface detection by constructing a comprehensive water database (DB) using existing digital and land cover maps. This database serves as an initial assumption for automated water index analysis. We utilized 1:5,000 and 1:25,000 digital maps of Korea to extract water surface, specifically rivers, lakes, and reservoirs. Additionally, the 1:50,000 and 1:5,000 land cover maps of Korea aided in the extraction process. Our research demonstrates the effectiveness of utilizing a water DB product as our first approach for efficient water surface extraction from satellite images, complemented by our second and third approachesinvolving NDWI analysis and k-means analysis. The image segmentation and binary mask methods were employed for image analysis during the water extraction process. To evaluate the accuracy of our approach, we conducted two assessments using reference and ground truth data that we made during this research. Visual interpretation involved comparing our results with the global surface water (GSW) mask 60 m resolution, revealing significant improvements in quality and resolution. Additionally, accuracy assessment measures, including an overall accuracy of 90% and kappa values exceeding 0.8, further support the efficacy of our methodology. In conclusion, thisstudy'sresults demonstrate enhanced extraction quality and resolution. Through comprehensive assessment, our approach proves effective in achieving high accuracy in delineating watersurfaces from satellite images.

• Proceedings of the Korea Water Resources Association Conference
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• 2009.05a
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• pp.1652-1657
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• 2009

종이지도, CAD 도면, 항공사진과 같은 형태로 구축되어 있는 저수지 퇴사자료는 자료의 훼손 변질 등에 대한 문제뿐만 아니라 자료관리를 위한 인력의 업무중복 및 시간부족에 따른 조사자료의 질의 저하 및 부정확성 문제 등 퇴사자료 관리에 있어 해결되어야 할 많은 문제점을 안고 있다. 이러한 문제점을 해결하기 위해 저수지 퇴사자료의 DB구축 및 자료관리방안 수립이 요구된다. 따라서 본 연구에서는 현재 구축되고 있는 항공사진과 같은 3차원 공간정보 DB구축으로 기존 자료와의 상호 활용성 미흡, 관련 사업의 연계성 부족 등의 문제점에 대처할 수 있는 체계적인 사업 추진방향을 제시하여 3차원 공간정보 DB구축 및 관리방안을 제시하였다. 이를 위해 본 연구에서는 저수지 퇴사자료 구축현황을 분석하고, 저수지퇴사 공간정보에 대한 구축방안을 수립하였으며, 구축된 공간정보의 효율적인 관리를 위한 저수지퇴사 공간정보 관리방안을 수립하였다. 이러한 공간정보 DB의 구축과 자료관리방안 수립으로 시 공간적 변화로 인한 저수지 퇴사를 쉽고 신속히 활용할 수 있는 공유기반 및 활용체계를 마련하게 되었으며, 효율적인 댐운영관리 및 수자원기초자료로도 활용할 수 있도록 하였다.

• Proceedings of the KIEE Conference
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• 2006.07d
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• pp.1889-1890
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• 2006

그동안 수처리 분야에서는 자체 DB가 탑재된 DCS 시스템을 통한 운영이 주를 이루었다. 본 사는 최근 수행한 프로젝트를 통해서 상용 DBMS인 Oracle9i를 사용하여 수처리 DB를 구축하였고, 구축된 DB는 현장에서 실제 수처리 시설의 운영에 사용되고 있다. 본 연구는 수처리 분야에서 상용 DBMS를 사용한 DB 구축과 운영 시스템 개발 전반에 관한 내용이다.

• The Journal of Internal Korean Medicine
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• v.37 no.3
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• pp.467-483
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• 2016

Objective: This study was performed to investigate the effect of IUS (Inulsan, an extract of Artemisiae capillaris (茵蔯), Curcumae longae (鬱金), and Crataegi fructus (山査)) on anti-hyperlipidemia, anti-oxidation, and anti-inflammation.Method: We administered water extracts of Artemisiae capillaris, Curcumae longae, and Crataegi fructus for three weeks to db/db mice (C57BL/Ks), animal models induced with type 2 diabetes mellitus. Mice were divided into three groups: normal (C57BL/6J mice group), control group (db/db mice without administration of IUS) and IUS group (db/db mice treated with IUS). Then we measured total cholesterol, LDL cholesterol, HDL cholesterol, and triglyceride in the serum after the oral administration of IUS.Results: 1. IUS did not show any cytotoxicity in RAW 264.7 cells. 2. IUS decreased AST, ALP, and creatinine levelsand did not show any liver or renal toxicity in the db/db mice. 3. IUS increased DPPH and ABTS radical scavenging activity and decreased ROS production in RAW 264.7 cells. 4. IUS significantly decreased IL-1β, IL-6, and TNF-α production in RAW 264.7 cells. 5. IUS increased HDL cholesterol and significantly decreased total cholesterol and triglyceride in db/db mice. 6. IUS significantly decreased the atherogenic index and cardiac risk factor. 7. In contrast with the control group, fat infiltration in the liver and aorta decreased in IUS treated mice. The cell nucleus was located in the central area in H&E staining of liver. And endomembranes also were more thinner than the control group in H&E staining of aorta.Conclusions: These results suggest that IUS might be effective in the prevention and treatment of dyslipidemia.