• Title/Summary/Keyword: Wataru 방법

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(Pattern Search for Transcription Factor Binding Sites in a Promoter Region using Genetic Algorithm) (유전자 알고리즘을 이용한 프로모터 영역의 전사인자 결합부위 패턴 탐색)

  • 김기봉;공은배
    • Journal of KIISE:Software and Applications
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    • v.30 no.5_6
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    • pp.487-496
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    • 2003
  • The promoter that plays a very important role in gene expression as a signal part has various binding sites for transcription factors. These binding sites are located on various parts in promoter region and have highly conserved consensus sequence patterns. This paper presents a new method for the consensus pattern search in promoter regions using genetic algorithm, which adopts the assumption of N-occurrence-per-dataset model of MEME algorithm and employs the advantage of Wataru method in determining the pattern length. Our method will be employed by genome researchers who try to predict the promoter region on anonymous DNA sequence and to find out the binding site for a specific transcription factor.

Search Method for Consensus Pattern of Transcription Factor Binding Sites in Promoter Region (프로모터 영역의 전사인자 결합부위 Consensus 패턴 탐색 방법)

  • Kim, Ki-Bong
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.9 no.5
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    • pp.1218-1224
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    • 2008
  • Located on the upstream of a gene, the promoter region that plays a very important role in the control of gene expression as a signal part has various binding sites for transcription factors. These binding sites are present in various parts of the promoter region and assume an aspect of highly conserved consensus sequence pattern. This paper deals with the introductions of search methods for consensus pattern, including Wataru method, EM algorithm, MEME algorithm, Genetic algorithm and Phylogenetic Footprinting method, and intends to give future prospects of research on this field.

Influence of Mechanical Properties of Painting Layers and Priming Methods to Weathering Resistance of Danchung (도막의 기계적 성질과 포수방법이 단청의 내후성에 미치는 영향)

  • Oh, Joon suk;Kawanobe, Wataru
    • Journal of Conservation Science
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    • v.17 s.17
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    • pp.19-32
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    • 2005
  • The exterior of Korean traditional wooden buildings have been painted with Danchung of painting method using glue and pigments. However because of losing traditional techniques and materials through the period of colonization and industrialization, many problems are occurring today. Especially after several years from painting, occurrence of scalings and flakings in painting layer is a serious problem. To improve weathering resistance of painting layer caused by stress from the difference of swelling and shrinkage between painting layer and wood plate, was examined by weathering tests. The stress is due to the hydrophilic property of wood, mechanical properties(tensile property and stress relaxation) of painting layer, and priming methods by various binders such as glue, acrylic emulsion(Primal AC-3444), acrylic resin(Paraloid B-72). Because stress relaxation of acrylic emulsion of which glasf transition temperature is below room temperature$(7^{\circ}C)$ is high, painting layers with acrylic emulsion generate no scalings and flakings and are in the most durable state in all weathering tests. Priming method which starts from low concentration to high concentration, is more effective to improve durability than other priming methods.

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New Classification Criteria and Database Code of Water Environment for Nature-Friendly River Work and Integrated Management of Watershed (자연친화적 하천사업 및 통합적 유역 관리를 위한 새로운 수환경 분류법 및 자료관리 프로그램의 개발)

  • Noguchi, Masato;Kang, Sang Hyeok;Kim, Joon Hyun;Nishida, Wataru;Fujisaki, Nobuhito
    • Journal of Environmental Impact Assessment
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    • v.7 no.2
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    • pp.103-112
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    • 1998
  • Nature-friendly river project has became common practice in Japan. In order to make it available for the conservation and rehabilitation of desirable water environment, water criteria for water environmental assessment must be established. Especially, the criteria estimating the effects on ecosystem in and around river should be constructed. In this paper, classification method for water quality has been developed using biological indices and applied to observed data in Honmyo River, Nagasaki, Japan. Modified PI method (BI') has been suggested and those of three most abundant species resulted effective estimate for an overall water quality with comparatively simple procedure. Extensive database management code was prepared for the comprehensive ecological monitoring of river basin, which includes various biota. That system enables easy access of all the ecological data for a dissemination of a sound and sustainable water environment. The result of this study could improve knowledge base, serve making consensus for citizens, and help river management plans. In Japan, citizen's realization and action are the most critical factor for nature-friendly river restoration project.

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