• Investigative Magnetic Resonance Imaging
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• 제21권1호
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• pp.20-27
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• 2017

Purpose: To evaluate quantification results of single breath-hold (SBH) magnetic resonance (MR) cine imaging compared to results of conventional multiple breath-hold (MBH) technique for left ventricular (LV) function in patients with cardiac arrhythmia. Materials and Methods: MR images of patients with arrhythmia who underwent MBH and SBH cine imaging at the same time on a 1.5T MR scanner were retrospectively reviewed. Both SBH and MBH cine imaging were performed with balanced steady state free precession. SBH scans were acquired using temporal parallel acquisition technique (TPAT). Fifty patients ($65.4{\pm}12.3years$, 72% men) were included. End-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV), ejection fraction (EF), myocardial mass, and LV regional wall motion were evaluated. Results: EF, myocardial mass, and regional wall motion were not significantly different between SBH and MBH acquisition techniques (all P-values > 0.05). EDV, ESV, and SV were significant difference between the two techniques. These parameters for SBH cine imaging with TPAT tended to lower than those in MBH. EF and myocardial mass of SBH cine imaging with TPAT showed good correlation with values of MBH cine imaging in Passing-Bablok regression charts and Bland-Altman plots. However, SBH imaging required significantly shorter acquisition time than MBH cine imaging ($15{\pm}7sec$ vs. $293{\pm}104sec$, P < 0.001). Conclusion: SBH cine imaging with TPAT permits shorter acquisition time with assessment results of global and regional LV function comparable to those with MBH cine imaging in patients with arrhythmia.

• 한국레이저가공학회지
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• 제14권2호
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• pp.8-12
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• 2011

As the aged population grows around the world, many medical instruments and devices have been developed recently. Among the devices, a drug delivery stent is a medical device which requires precision machining. Conventional drug delivery stent has problems of residual polymer and decoating because the drug is coated on the surface of stent with the polymer. If the drug is impregnated in micro hole array on the surface of the stent, the problem can be solved. Micro sized holes are generally fabricated by laser machining; however, the fabricated holes do not have an enough aspect ratio to contain the drug or a good surface finish to deliver it to blood vessel tissue. To overcome these problems, we propose a vibration-assisted machining mechanism with PZT (Piezoelectric Transducers) for the fabrication of micro sized holes. If the mechanism vibrates the eyepiece of the laser machining head, the laser spot on the workpiece will vibrate vertically because objective lens in the eyepiece shakes by the mechanism's vibration. According to the former researches, the vibrating frequency over 20kHz and amplitude over 500nm are preferable. The vibration mechanism has cylindrical guide, hollowed PZT and supports. In the cylinder, the eyepiece is mounted. The cylindrical guide has upper and low plates and side wall. The shape of plates and side wall are designed to have high resonating frequency and large amplitude of motion. The PZT also is selected to have high actuating force and high speed of motion. The support has symmetrical and rigid characteristics.

• 한국자기학회지
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• 제15권1호
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• pp.12-16
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• 2005

본 연구에서는 비정질 시료 $Fe_{87}Zr_{7}B_{6}$ 에 중성자르 조사시킨 후 자기화의 온도의존성, X-ray 회절과 복소 투자율을 측정하여 중성자 조산 전, 후의 자기적 특성 변화를 보았으며, 다양한 중성자 조사량에 따른 복소 투자율과 자기이력곡선을 측정하여 측정하여 중성자 조사량에 따른 지구벽 운동과 자기화 회전을 보았다. 실험결과 중성자 조사에 의한 지구벽 운동은 감소하였으며, 자기화 회전은 증가 한 것을 볼 수 잇었다. 또한, 자기이완 주파수는 지구벽 운동의 경우 증가하였으며, 자기화 회전에 의한 이완 주파수는 감소하였다. 자기이력곡선의 결과 중성자 조사 후 포화 자기화 값이 감소하는 것을 볼 수 있었는데 이러한 실험 결과로부터 중성자 조사 후 생긴 결함에 의해 지구벽 운동은 억제되었으며, 자기화 회전부분은 증가 한 것을 알 수 있었다.

• 멤브레인
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• 제13권1호
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• pp.37-46
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• 2003

하전된 멤브레인 미세기공으로 유체가 흐르는 경우는 계면동전기 효과가 작용하게 된다. 비선형 Poisson-Boltzmann 전기장과 흐름에 의해 유발되는 전기장 사이의 정전상호작용을 운동방정식의 외부작용 힘으로 고려하였다. 유한차분법으로 정전위 분포를 우선 산출하고, 이어서 Green 함수로 슬릿형 기공에 대한 Navier-Stokes 식의 해석해를 구하였다. 계면동전기적 유동에 의한 흐름전위를 관련된 물리화학적 인자들의 함수로 유도되는 해석적인 명확한 표현으로 제시하였다. 전기이중층, 표면전위, 그리고 기공벽면의 하전조건의 영향에 따른 유속분포와 흐름전위 변화를 고찰하였다 계산결과, 전기이중층 두께나 표면전위가 증가함에 따라 평균유속은 감소하는 반면에 흐름전위는 증가하였다.

• Journal of Cardiovascular Imaging
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• 제30권1호
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• pp.25-34
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• 2022

BACKGROUND: The purpose of this study was to assess the utility of a handheld device (HH) used during common daily practice and its agreement with the results of a standard echocardiography study (STD) performed by experienced sonographers and echocardiographer. METHODS: A prospective follow-up was conducted in an adult outpatient echocardiography clinic. Experienced sonographers performed the STD and an experienced echocardiographer performed the HH. STD included 2-dimensional images, Doppler and hemodynamics analysis. Hemodynamic assessment was not performed with the HH device because the HH does not include such technology. The images were interpreted by blinded echocardiographers, and the agreement between the reports was analyzed. RESULTS: A total of 108 patients were included; and the concordance for left ventricle (LV) ejection fraction (EF), wall motion score index, LV and right ventricle (RV) function, RV size, and mitral and aortic stenosis was excellent with κ values greater than 0.80. Wall motion abnormalities had good concordance (κ value 0.78). The agreement for LV hypertrophy, mitral and aortic regurgitation was moderate, and tricuspid and pulmonary regurgitation agreements were low (κ values of 0.26 and 0.25, respectively). CONCLUSIONS: In a daily practice scenario with experienced hands, HH demonstrated good correlation for most echocardiography indications, such as ventricular size and function assessment and stenosis valve lesion analyses.

• 대한핵의학회지
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• 제37권5호
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• pp.278-287
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• 2003

목적: 생존심근 진단에 있어 니트로글리세린 투여 Tc-99m-MIBI 게이트 심근SPECT의 진단성능을 휴식/지연재분포 Tl-201 심근SPECT와 비교하였다. 대상 및 방법: 22명의 관상동맥질환자에서 Tl-201 휴식/디피리다몰 부하 Tc-99m-MIBI 게이트 지연재분포 Tl-201 심근SPECT를 시행하였다. 이 때 게이트SPECT 시행 후 니트로글리세린 0.6 mg을 설하투여하고 연이어 그 자리에서 게이트SPECT를 1회 더 반복 시행하였다. 환자들에게 관상동맥우회로술을 시행하고 3개월 후 게이트 심근SPECT를 추적검사로 시행하였다. 20 분절 모델을 이용하여 각 분절에서 휴식, 지연재분포, 기저상태와 니트로글리세린투여 후의 심벽운동 및 수축기비후화 등을 정량하였다. 정량화된 생존심근 예측지표들 중, (1) 휴식기 Tl-201 섭취, (2) Tl-201 지연재분포, (3) 기저상태의 수축기비후화, (4) 니트로글리세린 투여 후의 수축 기비후화, 네 가지의 예측성능을 평가하고 비교하였다. 결과: 총 100개의 분절이 분석에 포함되었으며, 이 중 66개(66%)의 분절이 재관류 후 기능 회복을 보였다. 최적 기준점인 50%를 기준으로 하였을 때, ROC 곡선 분석에서 휴식기 Tl-201 섭취와 Tl-201 지연재분포의 민감도, 특이도는 각각 79%와 44%, 그리고 82%와 44%였다. 또한 15%를 기준으로 하여, 기저상태 수축기비후화와 니트로글리세린 투여 후 수축기비후화의 민감도, 특이도는, 각각 49%, 50%와 64%, 65%였다. ROC 곡선의 AUC는 니트로 글리세린 투여 후 수축기비후화가 기저시 수축기비후화에 비하여 유의하게 높았다(p=0.004). 결론: 니트로글리세린 투여 Tc-99m-MIBI 정량적 게이트 심근SPECT는 기능이상 심근에서 기능 회복을 예측하는데 유용한 검사이다.

• Structural Engineering and Mechanics
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• 제23권6호
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• pp.615-634
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• 2006

Seismic response of the liquid storage tanks isolated by the elastomeric bearings and sliding systems is investigated under near-fault earthquake motions. The fault normal and parallel components of near-fault motion are applied in two horizontal directions of the tank. The continuous liquid mass of the tank is modeled as lumped masses known as sloshing mass, impulsive mass and rigid mass. The corresponding stiffness associated with these lumped masses has been worked out depending upon the properties of the tank wall and liquid mass. It is observed that the resultant response of the isolated tank is mainly governed by fault normal component with minor contribution from the fault parallel component. Further, a parametric study is also carried out to study the effects of important system parameters on the effectiveness of seismic isolation for liquid storage tanks. The various important parameters considered are: aspect ratio of tank, the period of isolation and the damping of isolation bearings. There exists an optimum value of isolation damping for which the base shear in the tank attains the minimum value under near-fault motion. The increase of damping beyond the optimum value will reduce the bearing and sloshing displacements but increases the base shear. A comparative performance of five isolation systems for liquid storage tanks is also studied under normal component of near-fault motion and found that the EDF type isolation system may be a better choice for design of isolated tank in near-fault locations. Finally, it is also observed that the satisfactory response can be obtained by analysing the base-isolated tanks under simple cycloidal pulse instead of complete acceleration history.

• 한국유체기계학회 논문집
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• 제17권2호
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• pp.41-47
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• 2014

Experimental results are given for the vertical motion of water in the water chambers for wave energy converter aligned along the wave propagation direction in order to avoid the impulsive wave forces. This paper mainly focuses on the property of the amplitude of the vertical motion of the water surface in the chambers. The amplification has been investigated by dimensionless parameters of wave period to resonance period ratio of the U-shaped oscillation, $T/T_r$, chamber size to wave length ratio, l/L, water depth to wave length ratio, h/L, amplitude of up-down motion of water particles to draft of the front wall ratio, ${\zeta}/D$. It has been shown that l/L should be less than 0.1 and as $T/T_r$ approaches unity the up-down of the water in the chambers is amplified. Also, the structure of the walls which form th water chambers has been examined roughly. It is deduced that the chambers set on both sides of the hull of a single-point moored floating vessel is preferable to those set along a fixed structure such as breakwaters.

• 한국해양학회지
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• 제29권3호
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• pp.296-303
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• 1994

회전하는 원통형 이층 유체에 하층 유체와 동일한 밀도의 유체를 경사진 하층 바 닥의 둘레를 통하여 주입시 하층 내부는 일정한 수직 운동을 하게 되며 이러한 수직운 동은 결국 하층 유체에 Sverdrup type의 운동인 남향의 서안 경계류와 북향의 내부 운 동을 발생시킨다. 이때 $\beta$-효과와 동시에 하층 유체가 상층 경계면과 만나게 하므로써 소위 극전선 효과를 갖고 있는 상층 유체의 운동 특성을 관찰하였다. 서안에서 의 순 압성, 동안에서 의 경압성 운동이 뚜렷하게 나타나고 특히 동안 경계류의 남향과 서안 경계류의 남향은 서안에서 의 이안 현상을 야기시킨다. 상층에 $\beta$-효과를 증가시 서안 경계류의 폭이 감소하는 이안 현상후 내부에 "eddy" 모양의 흐름이 존재한다. 한편 경압성 Rossby wave는 동안 부근에서 뚜렷하게 관측되나 서쪽으로 진행하면서 소멸되 는 현상이 관측되었다. 하층 유체에 국지적 지형 효과서 준 경우 상층수의 서안 경계 류 및 동안 경계류가 민감하게 반응하여 동안에서는 정상파 형태의 운동이 나타나고 서안에서는 이안 현상 없이 경계류의 폭이 증가함을 보인다. 이는 하층의 순압성 운동 이 지형 효과를 느끼는 반면, 그 영향은 상층에 직접전달되지 못하고 있음을 보여주고 있는 것이라 사료된다. 상층의 $\beta$-효과 증가시 internal radius보다 훨씬 큰 규모의 파형이 내부에 존재하는 특성을 보여 주고 있다. 보여 주고 있다.

• Journal of Mechanical Science and Technology
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• 제17권6호
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• pp.844-853
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• 2003

In this paper, a dynamic analysis of the reciprocating compression mechanism of a small refrigeration compressor is performed. In the problem formulation of the mechanism dynamics, the viscous frictional force between the piston and the cylinder wall is considered in order to determine the coupled dynamic behaviors of the piston and the crankshaft. Simultaneous solutions are obtained for the equations of motion of the reciprocating mechanism and the time-dependent Reynolds equations for the lubricating film between the piston and the cylinder wall and for the oil films on the journal bearings. The hydrodynamic forces of the journal bearings are calculated by using a finite bearing model along with the Gumbel boundary condition. A Newton-Raphson procedure is employed in solving the nonlinear equations for the piston and crankshaft. The developed computer program can be used to calculate the complete trajectories of the piston and the crankshaft as functions of the crank angle under compressor-running conditions. The results explored the effects of the radial clearance of the piston, oil viscosity, and mass and mass moment of inertia of the piston and connecting rod on the stability of the compression mechanism.