• 한국컴퓨터그래픽스학회논문지
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• 제24권3호
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• pp.1-10
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• 2018

본 연구는 비대칭 가상현실 환경에 존재하는 HMD 사용자와 Non-HMD 사용자 모두에게 향상된 현존감을 제공하기 위하여 사용자의 체험 환경에 최적화된 몰입형 상호작용을 제안한다. 제안하는 몰입형 상호작용의 핵심은 HMD 사용자와 Non-HMD 사용자 사이의 비대칭 환경의 차이를 구분하여 사용자에게 최적화된 상호작용을 제시하는 것이다. 그리고 사용자 각각에게 주어지는 비대칭 가상현실 환경에서 향상된 몰입을 제공하여 현존감을 높이기 위하여 HMD 사용자에게는 공간의 몰입을 향상시키는 걷기 상호작용을, Non-HMD 사용자에게는 직접적인 조작을 통해 상황을 전체적으로 이해하고 관리함으로써 몰입을 향상시키는 손 기반 인터페이스를 설계한다. 마지막으로 몰입형 상호작용을 통해 모든 사용자가 향상된 현존감을 제공받으면서 동시에 각각의 체험에 환경에 특화된 경험을 하였음을 설문실험을 통해 검증한다. 이러한 과정들을 통하여 제안한 상호작용이 비대칭 가상현실에서 Non-HMD 사용자도 보조자가 아닌 참가자로써 HMD 사용자와 함께 몰입할 수 있음을 확인한다.

• 대한간호학회지
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• 제27권4호
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• pp.807-819
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• 1997

The purpose of the study was to identify the effects of a 12-week low-intensity exercise program on muscle strength, flexibility, balance, and cognitive characteristics related to the performance of activity of daily living(ADL). A total of 16 patients who were admitted to the medical unit of a general hospital in ChoongChung province were recruited, eight for the exercise group and eight for the comparison group. Four levels of low-intensity exercise from 'ROM on bed' to 'exercise while walking' were then applied to the exercise group according to their physical condition. During hospitalization, patients in the exercise group performed each level of the prescribed exercise with the researchers until they felt comfortable doing it independently. The researchers also visited the patients' homes after discharge to make sure they could perform the exercise with Theraband in their living environment. The exercise group was contacted by phone once a week to assess the frequency and intensity in which they performed the exercise as well as their physical condition. The subjects in the comparison group participated in measurements for the study without performing the exercise and were contacted by phone after discharge, in a matched time frame with the exercise group, to assess physical condition. Muscle strength, flexibility, balance, cognitive characteristics, and performance of ADL for the two groups were compared at the pretest and the posttest after the low-intensity exercise program by utilizing SPSSWIN and the results are as follows : 1) At the postest, measurements of muscle strengths showed that the strength of the dorsal flexor in the exercise group was significantly higher than in the comparison group. 2) Objective balance for the exercise group was significantly better than for the comparison group as measured by 'standing on one foot' and Tinetti gait and balance control. 3) The exercise group showed significantly higher task self-efficacy than the comparison group. 4) Perceived exertion for ADL for the exercise group was significantly lower than for the comparison group. 5) Improvement of performance of ADL without assistance was significantly higher for the exercise group than the comparison group. The findings suggest that a low-intensity exercise program would be useful for the elderly who show decline in their physical functioning due to hospitalization by partly improving physical strength, task self-efficacy, and performance of ADL. Directions for further research on issues of motivating people to exercise as well as of standardizing various types of exercise were discussed.

• 가정과삶의질연구
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• 제32권6호
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• pp.125-138
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• 2014

The purpose of this study is to examine the effects a music group therapy program has on cognitive function and life satisfaction. We targeted the elderly who are receiving service at a daycare center. This study monitored seventeen elderly subjects who were available for language communication, walking, and defecation function even if the subject had a slight mind-body function disorder based on using the service of the daycare facilities. The subjects visited each of the welfare centers one week prior to the Korean classical music group therapy program. We conducted a pre-test of MMSE-K(Mini-Mental State Examination, Korean version) modified by Park and Gwon(1989). We also supplemented the MMSE developed by Folstein(1975) and LSI-A(Life Satisfaction Index) for the elderly developed by Neugarten, Havighurst and Tobin(1961). We conducted the Korean classical music group therapy program for 15 sessions at 50 minutes each for 1~2 times a week from July 9 to September 13, 2013 at the daycare center for OO senior welfare center. The welfare center belongs to the experimental group, excluding the OO general welfare center, which is the control group. Finally, we carried out the post-test of the MMSE-K and LSI-A in the same manner as the pre-test. We carried out the post-test on July 17, 2013, 4 days after concluding the Korean classical music group therapy program. A t-test was used in order to analyze the differences in cognitive function and life satisfaction according to each group. We used SPSS/WIN 18.0 program. This study has significance by proving that the use of Korean classical music is conducive in the improvement of cognitive function and life satisfaction of the elderly at the daycare facilities. Also, we presented the actual contents of the study to the clinical field.

• 대한한방내과학회지
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• 제35권1호
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• pp.12-23
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• 2014

Objectives : The purpose of this study was to report possibility of acupuncture or moxibustion for the treatment of Parkinson's disease (PD) by reviewing literature about its effectiveness. Methods : In this review, PubMed, SCOPUS, Science Direct and CINAHL of EBSCOhost were used to search medical journals, using keywords "Parkinson's disease and acupuncture" and "Parkinson's disease and moxibustion". The search range included randomized controlled trials (RCT) about Parkinson's disease combined with another disease and other treatments with acupuncture or moxibustion. Non-randomized controlled trial (nRCT), case study, animal experiment, human experiment, review, survey, essay, letter, and protocol for review were excluded. Results : From 311 studies, 111 were selected during the title and the screening. Finally, 16 RCTs (15 for acupuncture research and one for moxibustion) were included in this review, after scanning and matching the inclusion and exclusion criteria. The number of patients varied between 5 and 88. A total of 12 studies using electroacupuncture (EA) were classified into acupuncture studies. The body acupuncture studies numbered 4, scalp acupuncture 4, body and scarp acupuncture mixed studies 4, and bee venom, ear and abdomen acupuncture were each one study. In evaluation methods, total effective rate method was used in 9 studies, the Unified Parkinson's Disease Rating Scale (UPDRS) was used in 8, and the Webster score in 2. In addition, the Berg balance scale (BBS), 30 m walking time, steps to walk 30 m, PD motor function score, and Motor Performance Series by Schoppe (MLS) method were used for evaluation. In 15 of the 16 studies, the verum acupuncture group showed significant improvement compared with the control. In 9 studies using total effective rate method, the effective rate was reported as 80.0-97.3% in verum acupuncture groups and 52.6-86.4% in controls. Conclusions : Acupuncture may be a plausible alternative method to care for the long term symptoms and treat movement impairment of Parkinson's disease. However, to confirm this result, high quality studies including randomized, placebo-controlled double-blind trials are warranted.

• The Korean Journal of Pain
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• 제14권1호
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• pp.83-92
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• 2001

Background: This study was undertaken to observe the functional changes of the hind limb and histopathological changes in the sciatic nerve after an injection of alcohol or phenol, which are commonly used neurolytic agents, highlighting the time of recovery. Methods: Forty-eight Sprague-Dawley rats weighing 200-300 g were used for the experiment. Histopathological changes under the electron microscope, were observed in the distal part of the sciatic nerve, into which 0.1 ml of alcohol or phenol was injected. This was severed in 3 rats of each group at 10 minutes, 1 hour, 24 hours, 3 days, 1, 2, 4 and 6 weeks later. The functional changes in the hind limbs were observed for 6 weeks by noting their walking pattern. Results: Following the injection of alcohol or phenol into the right sciatic nerve, the right hind limb showed a severe pronounced motor weakness and obvious gait changes. About 2 weeks later, gradual improvement of gait changes began, and after 6 weeks, the motor weakness and gait changes were no longer perceptible in both groups. The findings of any histopathological change were similar in both alcohol or phenol groups. At 10 minutes after injection, destructive lesions were confined to the unmyelinated fibers and the myelin sheath of small the myelinated fibers. On the 3rd day and at 1 week, pathologic changes in axonal fibers and Schwann cells were in being phagocytized in spite of myelin restitution. From 2 to 4 weeks, axonal regeneration and remyelination appeared at the same time a myelin disintegration and axonolysis. At 6 weeks, neural regeneration was similar to that of the contralateral control group. Conclusions: These results suggest that functional and histopathological changes, after injection of neurolytics into the peripheral nerves, are quite similar in both alcohol and phenol groups. The progression of functional and histopathological changes become more obvious according to the time interval following the injection. Consequently, side effects that develop following the use of alcohol or phenol may begin to improve around the time that nerve regeneration occurs, i.e., two to four weeks later.

• 한국산학기술학회논문지
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• 제13권3호
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• pp.1194-1202
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• 2012

최근에 발견된 Adiponectiin과 gut hormone은 지질대사와 인슐린 저항성, 그리고 식욕에 영향을 주는 것으로 보고되고 있다. 이 연구의 목적은 장기간 트레이닝을 한 고등학교 씨름선수 16명(경량급=8, 장사급=8)을 대상으로 일시적 운동을 실시하여, 운동 전 후의 혈중 Adiponectin과 Gut hormones 농도의 변화와 체중차이에 의한 농도에 차이가 있는지를 구명하고 체중의 차이가 운동의 효과에 어떠한 영향을 미치는지를 구명하고자 하였다. 실험방법으로 일시적 운동프로그램은 40분간 걷기를 한 후, 5분간 all-out 달리기를 실시하였으며 운동 전 후에 혈액을 채혈하여 분석하였다. 이 연구의 결과에서 Adiponectin과 Ghrelin의 농도는 경량급선수가 장사급선수보다 유의하게 높은 것으로 나타났으며(p<.05), 인슐린의 농도에서는 반대로 장사급선수가 경량급선수보다 유의하게 높은 것으로 나타났다(p<.01). 또한, 운동 전 후의 유의한 차이는 오직 글루카곤에서 운동 후에 유의하게 증가하였으며(p<.01), 다른 모든 변인에서 운동 전 후의 유의한 차이는 나타나지 않았다. 이 연구의 결과에서는 Adiponectin과 인슐린, Ghrelin 등의 혈중 농도에 대한 일시적인 운동 효과는 없었으며 체중 차이에 의해서 변화를 보였고, 글루카곤의 경우에만 일시적인 운동에 영향을 받아 증가되는 것으로 나타났다. 따라서 Adiponectin과 인슐린, Ghrelin 등의 농도는 지속적인 운동의 효과와 체중 차이에 영향을 받는 것으로 생각되며 글루카곤은 일시적인 운동에도 효과가 있는 것으로 사료된다.

• 한국콘텐츠학회논문지
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• 제20권9호
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• pp.486-493
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• 2020

본 연구는 뇌졸중 환자에게 요추부 안정화 운동프로그램을 적용하여 정적, 동적운동의 균형 및 보행에 어떠한 영향을 미치는지 보고자 하였다. 27명의 뇌졸중 환자 중 실험군 14명과 대조군 13명으로 구분하고 하루 30분 주 4회로 6주간 실시하였다. 변인은 요추부 안정화 운동 전-후로 정적, 동적기립균형 능력과 보행 능력 확인 하였다. 결과는 IBM SPSS(19.0 version)을 이용하여 전-후 차이검증과 집단간 차이 검증을 위해 t검증과 이원량분석을 실시하였다. 유의수준은 α=.05로 설정하고 다음과 같은 결과를 얻었다. 첫째, 요추부 강화 운동 후 정적기립 균형에서 통계적으로 유의한 차이를 보였다(P<.05). 둘째, 요추부 강화 운동 후 동적 기립균형에서 통계적으로 유의한 차이를 보였다(P<.05). 셋째, 요추부 강화 운동 후 보행동작에서 통계적으로 유의한 차이를 보였다(P<.05). 집단 간 상호 작용에서도 유의한 차이를 보였다. 이러한 결과는 뇌졸중 환자에게 다양한 요추부 운동의 필요성이 제기 되고 요추부 안정화 운동을 통해 신체치료 및 건강증진에 도움을 줄 수 있을 것으로 판단된다. 뇌졸중 환자의 삶의 질에서도 긍정적 영향을 미칠 것으로 사료 되며 다양한 요추부 운동 적용 연구가 이루어져야겠다.

• 한국산학기술학회논문지
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• 제18권5호
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• pp.467-474
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• 2017

본 연구의 목적은 만성 뇌졸중 환자 8자 모양 경로 보행 검사(Figure-of-Eight Walk Test, F8WT)의 측정자간 절대적 신뢰도와 타당도를 알아보고자 하였다. 만성 뇌졸중 환자 36명을 대상으로 하였으며 F8WT 소요 시간의 측정자간 신뢰도는 급간내상관계수(Intra Class Coefficient, $ICC_{2,1}$)를 구하였고, 절대적 신뢰도는 측정의 표준 오차값(Standard Error Measurment, SEM)과 최저 실제 차이(Small Real Difference, SRD)를 구하였다. F8WT 소요시간의 타당도는 뇌졸중 자세 평가 척도(Postural Assessment Scale for Stroke, PASS)와 체간 장애 척도(Trunk Impairment Scale, TIS)간의 스피어만 상관 계수(Spearman Correlation Coefficient)를 구하였다. 연구 결과 F8WT 소요 시간의 측정자간 신뢰도 ICC=0.95(0.91~0.97)로 매우 높았고, SEM과 SRD는 각각 1.02점, 2.82점으로 수용할 만 하였다. F8WT 소요 시간은 PASS(r=-0.82), TIS(r=-0.85)와 유의한 상관관계가 있는 것으로 나타났으며, 뇌졸중 환자의 특이성 장애인 자세 및 체간 조절과 유의한 관련성이 있는 것으로 확인되었다. 따라서 F8WT는 만성 뇌졸중 환자의 보행 능력을 평가하는데 유용한 평가 도구로 사용될 수 있을 것이다.

• 디지털융복합연구
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• 제18권2호
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• pp.175-182
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• 2020

본 연구는 배구 프로그램이 중학교 지적장애 학생의 체력과 주의집중력에 미치는 효과를 검증하는데 목적이 있다. 배구 프로그램의 효과성을 검증하기 위해 체력과 주의집중력에 대해 분석하였으며, 배구 프로그램의 실험집단 대상을 주 3회 90분씩 12주간 총 36회 적용하였으며 체력과 주의집중력 효과성을 검증하기 위하여 PAPS-D 지적장애 학생용 검사 및 주의집중력에 효과성을 검증하기 위하여 ATA 주의집중력 검사를 사용하여 분석하였다. 배구 프로그램에 참가한 지적장애 학생이 참여하지 않은 지적장애 학생보다 심폐기능에 6분 걷기의 수치가 향상된 것으로 나타났으며. 참가한 지적장애 학생이 참여하지 않은 지적장애 학생보다 근기능과 관련된 윗몸 말아 올리기, 유연성과 관련된 윗몸 앞으로 굽히기가 향상된 것을 알 수 있으며, 순발력에 관련된 제자리멀리뛰기에서 유의한 차이가가 나타났다. 또한 선택적 주의집중력 향상에서는 긍정적 영향을 주었음을 확인할 수 있으며, 중학교 지적장애 학생의 자기통제력, 지속적 주의력 변화, 선택적 주의력 변화가 향상에 긍정적인 영향을 미쳤음을 확인할 수 있었다.

• Journal of Crop Science and Biotechnology
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• 제10권1호
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• pp.50-56
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• 2007

Barley S-adenosylmethionine synthetase1 gene, which was differentially expressed in seed development of extra early barley, was regulated by the phytohormones and abiotic stresses. In order to identify the regulation regions which were involved in transcriptional control of the phytohormones and abiotic stresses, we isolated 1459 bp fragment of HvSAMS1 gene promoter using genome walking strategy and deletion series were constructed. Deleted upstream fragments(-1459, -1223, -999, -766, -545, -301 bp) were fused to the GUS reporter gene and evaluated via Agrobacterium-mediated transient expression assay. Increased GUS activity of HvSMAS1 promoter -301/GUS construct under each of NaCl, $GA_3$, ABA and ethylene application was found. However, GUS activity was negligible in the leaves transformed with the HvSMAS1 promoter(-1459, -1223, -999, -766 and -545)/GUS constructs. No significant induction of GUS activity was observed for the ethionine and spermidine treatments. In order to locate promoter sequence of the HvSAMS1 gene that was critical for the activation of gene expression, deletion and addition promoter derivatives(+, includes 43 bp of 5' ORF) of the HvSAMS1 gene fused to the GUS reporter gene were applied. The tobacco leaves which harbored the additional HvSAMS1 promoter(-1459+, -1459 to -546, -545+ and -301+)/GUS construct did not significantly induce GUS activity as compared to the HvSAMS1 promoter(-1459, -545 and -301)/GUS constructs under each of NaCl, ABA and $GA_3$ treatment. However, the GUS activity was high in the tobacco leaves which harboring the -211 to -141 regions of the HvSAMS1 promoter. This result suggested that HvSAMS1 gene expression might be regulated by this region(from -211 to -141).