• 대한의용생체공학회:의공학회지
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• 제44권6호
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• pp.377-383
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• 2023

Purpose: There is increasing attention to the application of transcranial direct current stimulation (tDCS) for enhancing cognitive functions in subjects to aging, mild cognitive impairment (MCI), and Alzheimer's disease (AD). Despite varying treatment outcomes in tDCS which depend on the amount of current reaching the brain, there is no general information on the impacts of anatomical features associated with AD on tDCS-induced electric field. Objective: The objective of this study is to examine how AD-related anatomical variation affects the tDCS-induced electric field using computational modeling. Methods: We collected 180 magnetic resonance images (MRI) of AD patients and healthy controls from a publicly available database (Alzheimer's Disease Neuroimaging Initiative; ADNI), and MRIs were divided into female-AD, male-AD, female-normal, and male-normal groups. For each group, segmented brain volumes (cerebrospinal fluid, gray matter, ventricle, rostral middle frontal (RMF), and hippocampus/amygdala complex) using MRI were measured, and tDCS-induced electric fields were simulated, targeting RMF. Results: For segmented brain volumes, significant sex differences were observed in the gray matter and RMF, and considerable disease differences were found in cerebrospinal fluid, ventricle, and hippocampus/amygdala complex. There were no differences in the tDCS-induced electric field among AD and normal groups; however, higher peak values of electric field were observed in the female group than the male group. Conclusions: Our findings demonstrated the presence of sex and disease differences in segmented brain volumes; however, this pattern differed in tDCS-induced electric field, resulting in significant sex differences only. Further studies, we will adjust the brain stimulation conditions to target the deep brain and examine the effects, because of significant differences in the ventricles and deep brain regions between AD and normal groups.

• 보존과학연구
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• 통권25호
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• pp.119-132
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• 2004

Annals of the Joseon Dynasty is the authentic record of the historical facts and events taken place throughout the entire period of 472 years(25 generations, 1392~1863)described in a chronological order. The tremendous volume of the records contains the factual events taken place in almost all the fields of the Joseon Dynasty ranging from politics, economy to history of the dynasty. Not only because of its affluent contents but also with the precision of its records, it was designated as the National Treasure No. 151 in1973 by the Korean government and also registered as the Memory of the World by UNESCO in October 1997.This study is to report a exhaustive investigation results on the conservation state of annals of the Joseon Dynasty, especially Mt. Jeongjoksan edition, under the storage of the Kyujanggak in order to obtain the current condition, and thereby to estimate the any deterioration of the waxed volumes in the future. According to results of the investigation, we are going to verify damage causes of annals of the Joseon Dynasty, and to consider scientific conservation methods for the permanent preservation of invaluable cultural heritage. The major problem with the preservation of annals has arisen particularly from the deterioration of the waxed volumes of the Mt. Jeongjoksan edition. In order to provide for the counter measures for this problem, we have conducted twice investigations(first :1998~1999, second : 2003) to the internal and external conditions of waxed volumes(Annals of King Taejo~Annals of King Myeongjong).The result of the investigation has indicated that the paper quality of the some of the waxed volumes (Annals of King Taejong~Annals of King Sejong) is cracked and folded and the pages are imbedded to each other due to the hardened or congealed wax on the paper. Some of the pages are even getting moldy. And in order to detect as to whether“ there has been any deterioration progressed to the waxed books in the modern storage facility of the Kyujanggak equipped with constant temperature and humidity condition, the first investigation(1998~1999) and the second investigation(2003) have recorded the values of acidity, whiteness and moisture rate of the waxed paper, reporting an observation that there has been no difference on the measuring items. This indicates that no virtual deterioration has been progressed so far to the waxed volumes preserved in the Kyujanggak. Also, except for the causes of deterioration to the paper by insects and microorganisms, the major cause for the paper damage seems to the change of moisture of the paper caused from the alteration of the temperature and humidity of the storage environment. With this understanding in mind, we have conducted an environmental investigation on the three selected points of the storage in the aspects of the temperature, humidity, air current, $CO_2$,HCHO, and $SO_2$.It has been observed that the temperature stood at $16.9^{\circ}C~20.2^{\circ}C$ and the humidity was stable between 53%~56% during the period of the investigation. The concentration of the carbon monoxide and carbon dioxide of the storage were very similar to those in the air. These data lead to presume that there is no problem in the aspect of carbon oxidization. But the concentration of sulfur dioxide, hydrogen sulfide and formaldehyde of the storage were detected a little higher than those of standard. Therefore, we consider that it is necessary to ventilate the internal air of the store room by means of operating air purification devices.

• 한국비블리아학회지
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• 제2권1호
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• pp.178-210
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• 1974

It needs to put into practice the systems analysis in the analysis of some operations and status of library for the purpose of systematizing the work of reforming in the new easier form to process, to storage, to retrieve and to make use of the increasing informations and data of library. In this study, some of systems which are generally using in every library was caught in the case study of K university library. Having analyzed them with the two methods of the flowcharting and mathematical analysis, we found the obstructive factors in operation. As the result of this research, it was gained the new system as the alternative one. A. Alternative System B. Advantages of alternative systems 1. In the reference room When it converts the present system into the new system, it can profit 6.771 won/user (13.815won-7.044won=6.771 won). Therefore, a half the average required cost of the present system can be saved. If this saving would be alloted for the cost 33,000won required to make the cataloging cards, it would be taken for 94 days (33,000 won ${\div}$ 6,771 won/user=4,874users. 4,874users ${\div}$ 52users/day=94days) to get it. The saving cost/year by the new system will be 95,417 won, and in the first year the initial cost (33,000won) reduces the saving cost to 62,417won. 2. In the periodical room The average required time for using the materials of the present system is 17 minutes/user and the average required cost/user is 23.775won, while the average required time of the new system is 4 minutes and the average required cost/user is 5.33won. Therefore, the new system has profit 4 times of the present system. Accordingly, it occurs when the dispersed periodical materials get together. 3. In the classification and cataloging When one processes - the oriental books - by the Linear Programming Technique, the maximum of the process can be increased from 11.6 volumes per librarian of the present system to 12 volumes per librarian of the new system increased 0.4 volume in a day, and cataloging by the manual printer can be shorten from 3 minutes per card of the present system to 1.5 minutes per card of the new system. Consequently, we can complete the other operations (books equipment, updating of cataloging cards, etc.) with 141 minutes which are saved in the course of the afore-mentioned works. 4. In the status of collections The average growth rate of 4 years from 1968 to 1971 is 9.825 %, and that of the purchased materials is 6.2% similar to the advanced nations, but it has the different position from 215,000 volumes by the Standard Degree for Establishment of College and University, and the difference between the total collections 151,671 volumes and Dunns' growth model ($N_t=N_oe^{-at}$) claimed by Leimkuhler 155,297 volumes in 1971 is 3,626 volumes, and for the purpose of compensation the difference, we found the fact that it needs to have the increased budget of 24~30% per year, Thus, if the budget of 24~30 % per year. Thus, if the budget would be increased per year as the rate of the afore-mentioned figure, it would be reached at the Standard Degree for Establishment of College and University in 1975, and thereafter, it can be decreased to the lebel which is able to maintain the growth rate of 5~6% per year.

• 한국지능시스템학회논문지
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• 제24권5호
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• pp.518-528
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• 2014

본 논문에서는 4차원 시공간 (4D-ST, [x,y,z,t]) 특징을 이용하여 행동 방향을 인식하는 방법을 제안한다. 이를 위해 4차원 시공간 특징점 (4D-STIPs, [x,y,z,t])을 제안하였고, 이는 여러 다른 뷰에서 촬영한 이미지들로부터 복원된 3차원 공간 (3D-S, [x,y,z]) 볼륨으로부터 계산된다. 3차원 공간정보를 갖고 있는 3D-S 볼륨과 4D-STIPs는 2차원 공간 (2D-S, [x,y]) 뷰로 사영을 하여 임의의 2D-S 뷰에서의 특징을 생성해 낼 수 있다. 이 때, 사영 방향을 결정 할 수 있으므로, 학습 시 방향에 대한 정보를 포함하여 행동 방향을 인식 할 수 있다. 행동 방향을 인식하는 과정은 두 단계로 나눌 수 있는데, 우선 어떤 행동인지를 인식하고 그 후, 방향 정보를 이용하여 최종적으로 행동 방향을 인식한다. 행동 인식과 방향 인식을 위해, 사영된 3D-S 볼륨과 4D-STIPs은 각각 움직이는 부분과 움직이지 않는 부분에 대한 정보를 담고 있는 motion history images (MHIs)와 non-motion history images (NMHIs)로 구성된다. 이러한 특징들은 행동 인식을 위해, 방향 정보에 상관없이 같은 행동이면 같은 클래스로 분류되어 support vector data description (SVDD) 분류기로 학습되고, support vector domain density description (SVDDD)을 이용하여 인식된다. 인식된 행동에서 최종적으로 방향을 인식하기 위해 각 행동을 방향 클래스로 분류하여 SVDD 분류기로 학습하고 SVDDD로 인식한다. 제안된 방법의 성능을 보이기 위해서 INRIA Xmas Motion Acquisition Sequences (IXMAS) 데이터셋에서 제공하는 3D-S 볼륨을 사용하여 학습을 하고, 행동 방향 인식 실험이 가능한 SNU 데이터셋을 구축하여 인식 실험을 하였다.

• Asia pacific journal of information systems
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• 제24권4호
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• pp.559-575
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• 2014

Individual investors are increasingly flocking to message boards to seek, clarify, and exchange information. Businesses like Seekingalpha.com and business magazines like Fortune are evaluating, synthesizing, and reporting the comments made on message boards or blogs. In March of 2012, Yahoo! Finance Message Boards recorded 45 million unique visitors per month followed by AOL Money and Finance (19.8 million), and Google Finance (1.6 million) [McIntyre, 2012]. Previous studies in the finance literature suggest that online communities often provide more accurate information than analyst forecasts [Bagnoli et al., 1999; Clarkson et al., 2006]. Some studies empirically show that the volume of posts in online communities have a positive relationship with market activities (e.g., trading volumes) [Antweiler and Frank, 2004; Bagnoli et al., 1999; Das and Chen, 2007; Tumarkin and Whitelaw, 2001]. The findings indicate that information in online communities does impact investors' investment decisions and trading behaviors. However, research explicating the correlation between information on online communities and stock market activities (e.g., trading volume) is still evolving. Thus, it is important to ask whether a volume of posts on online communities influences trading volumes and whether trading volumes also influence these communities. Online stock message boards offer two different types of information, which can be explained using an economic and a psychological perspective. From a purely economic perspective, one would expect that stock message boards would have a beneficial effect, since they provide timely information at a much lower cost [Bagnoli et al., 1999; Clarkson et al., 2006; Birchler and Butler, 2007]. This indicates that information in stock message boards may provide valuable information investors can use to predict stock market activities and thus may use to make better investment decisions. On the other hand, psychological studies have shown that stock message boards may not necessarily make investors more informed. The related literature argues that confirmation bias causes investors to seek other investors with the same opinions on these stock message boards [Chen and Gu, 2009; Park et al., 2013]. For example, investors may want to share their painful investment experiences with others on stock message boards and are relieved to find they are not alone. In this case, the information on these stock message boards mainly reflects past experience or past information and not valuable and predictable information for market activities. This study thus investigates the two roles of stock message boards-providing valuable information to make future investment decisions or sharing past experiences that reflect mainly investors' painful or boastful stories. If stock message boards do provide valuable information for stock investment decisions, then investors will use this information and thereby influence stock market activities (e.g., trading volume). On the contrary, if investors made investment decisions and visit stock message boards later, they will mainly share their past experiences with others. In this case, past activities in the stock market will influence the stock message boards. These arguments indicate that there is a correlation between information posted on stock message boards and stock market activities. The previous literature has examined the impact of stock sentiments or the number of posts on stock market activities (e.g., trading volume, volatility, stock prices). However, the studies related to stock sentiments found it difficult to obtain significant results. It is not easy to identify useful information among the millions of posts, many of which can be just noise. As a result, the overall sentiments of stock message boards often carry little information for future stock movements [Das and Chen, 2001; Antweiler and Frank, 2004]. This study notes that as a dependent variable, trading volume is more reliable for capturing the effect of stock message board activities. The finance literature argues that trading volume is an indicator of stock price movements [Das et al., 2005; Das and Chen, 2007]. In this regard, this study investigates the correlation between a number of posts (information on stock message boards) and trading volume (stock market activity). We collected about 100,000 messages of 40 companies at KOSPI (Korea Composite Stock Price Index) from Paxnet, the most popular Korean online stock message board. The messages we collected were divided into in-trading and after-trading hours to examine the correlation between the numbers of posts and trading volumes in detail. Also we collected the volume of the stock of the 40 companies. The vector regression analysis and the granger causality test, 3SLS analysis were performed on our panel data sets. We found that the number of posts on online stock message boards is positively related to prior stock trade volume. Also, we found that the impact of the number of posts on stock trading volumes is not statistically significant. Also, we empirically showed the correlation between stock trading volumes and the number of posts on stock message boards. The results of this study contribute to the IS and finance literature in that we identified online stock message board's two roles. Also, this study suggests that stock trading managers should carefully monitor information on stock message boards to understand stock market activities in advance.

• 한국지리정보학회지
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• 제18권2호
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• pp.149-160
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• 2015

본 연구는 생태계 관리권역 내 남한강 상류지역을 대상으로 제5차 국가산림자원조사의 표본점자료를 기반으로 한 직접추정법과 합성추정법에 의한 층화별(임상 영급) 임목축적을 산출하였으며, 공간단위에 따른 오차검증을 통하여 최적의 추정방법을 비교 분석하였다. 직접추정법은 대상지내의 표본점 자료만을 활용하였으며, 합성추정법은 대상지뿐만 아니라 공간확장지역의 표본점 정보를 활용하여 임목축적을 추정하였고, 공간확장기준은 4가지(권역, 지역, 구역, 거리)를 적용하였다. 직접추정법에 의한 ha당 평균임목축적은 $143.5m^3/ha$이었으며, 합성추정법에 의한 ha당 평균임목축적은 구역, 거리, 지역, 권역기준의 순으로 각각 $146.9m^3/ha$, $144.8m^3/ha$, $139.8m^3/ha$, $138.6m^3/ha$ 추정되었다. 직접추정법에 의한 표준오차는 $1.79m^3/ha$이었으며, 합성추정법에 의한 표준오차는 공간확장기준에 상관없이 $1.83m^3/ha$으로 차이가 없었다. 한편, 임상별 표준오차는 추정방법과 확장지역에 관계없이 활엽수림이 ${\pm}2.3m^3/ha$으로 가장 낮았으며, 혼효림과 침엽수림이 각각 ${\pm}3.3m^3/ha$과 ${\pm}4.8m^3/ha$의 순으로 추정되었다.

• 동의생리병리학회지
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• 제18권6호
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• pp.1580-1584
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• 2004

On the basis of the widely collected fork prescriptions, long clinical practice of himself, together with integration of all the good points of earlier medical specialists, 孫思邈 wrote 『千金方』 of thirty volumes. Among them Volumes 『食治』 (Food Therapy) and 『養性』(Cultivating the Character) are especially meaningful for in gerontology. Thirty years after its completion, as a supplement, he wrote another thirty volumes of 『千金翼方』. Mr. Sun integrated his discoveries in the treatments of the aged patients, and his opinions for longevity into the Volumes 『養性』 (Cultivating the Character), 『?穀』(Fasting), 『退居』(Retirement), 『補益』(Supplementation). Thus he laid down the basic foundation for the gerontology of Chinese medicine. 『千金要方』 and 『千金翼方』 by Mr. Sun discuss mainly the prevention of illness for aged patients. As for the function of food therapy, he explains: 'Food can dispel evil elements of the body and settle down its organs. It can further bring pleasure to man's spirit and help the circulation of blood and breath.' He then propose the major method of food therapy: 'For a medical doctor, he should understand the causes of disease, then treat it with food. Only after the food treatment fails, medicine is employed.' He thinks that medicine does work in treatment, but it also creates imbalance in the body, and makes the latter vulnerable to outside harms. Therefore, a good doctor is the one who cures the disease and bring pleasure to the patient with food. He stresses that food therapy is always a priority. Mr. Sun prefers animal's organs in the food therapy for aged. For example, he uses powder of sheep's kidney to treat the lumbago. He suggests the viewpoint of 'Curing man's organs with animal's organs' and 'Strengthening man's organs with animal's organs,' and sets the theoretical foundation of 'Organic Treatment.' Mr. Sun's gerontology and food therapy received further development latter. The prescriptions contained therein had been widely used in 王懷隱's 『太平聖惠方』 and 陳直's 『養老奉親書』, both in the Song Dynasty. Eventually they had become a science of food therapy for aged patients.

• 한국도서관정보학회지
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• 제24권
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• pp.1-44
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• 1996

This study is to analyze correlations between 10 factors related to university libraries and the number of professional staff, nonprofessional staff, and total library staff of university libraries in Korea and United States of America. The results of this study are summarized as follows: 1. In the case of Korea, there are high positive correlations between the number of total library staff and 7 of 10 variables (coefficient : 0.76-0.99) ; between the number of professional staff and 7 of 10 variables, same as the above (coefficient : 0.76-0.99) ; between the number of nonprofessional staff and 4 of 10 variables (coefficient 0.73-0.93). In the case of America, there are high positive correlations between the number of total library staff and 6 of 10 variables (coefficient : 0.74-0.97) ; between the number of professional staff and 5 of 10 variables (coefficient : 0.78-0.87): between the number of nonprofessional staff and 6 of 10 variables (coefficient : 0.73-0., 96). 2. All the. rank orders of correlation coefficients of two countries show little significant difference, by the results of the Spearman's Rank Order Correlation analysis (coefficient : total staff, 0.9152: professional staff, 0.8667 ; nonprofessional staff, 0.9030) 3. In the case of Korea, among the above factors, correlations of the total university expenditure and the library expenditure show a significant difference more than ones of the other factors. On the other hand, in the case of American professional staff, the correlations of the library expenditure, the library materials expenditure and the volumes in library show a significant difference more than ones of the other factors, while in the case of American nonprofessional staff, only the library expenditure shows a significant difference more than the others. 4. In the results of the correlation analysis between the professional staff and nonprofessional staff in Korea, the number of graduate enrollments, volumes in library, library expenditure and total university expenditure show higher positive correlation to the professional staff than the nonprofessional staff. However, in the case of America, the library expenditure and the library materials expenditure show higher positive correlation to the nonprofessional staff than the professional staff, while the university expenditure per student shows higher positive correlation to the professional staff. 5. In the results of the correlation analysis between Korea and America, in the case of the total library staff, the undergraduate enrollments, the total university expenditure and the library expenditure show higher positive correlation to Korea than America, and in the case of the professional staff, the graduate, enrollments, the volumes in library and the above 3 factors also show higher positive correlation to Korea than America. But in the case of the nonprofessional staff, the graduate enrollments, the volumes in library and library materials expenditure show higher correlation to America than Korea, while the total university expenditure shows the o n.0, pposit phenomenon of the above. And the other factors by the type of staff are little significant difference between two countries.

• 펄프종이기술
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• 제44권5호
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• pp.72-79
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• 2012

In this study, to understand the aging factor and mechanism in different partitions of the beeswax-treated volumes, the duplicated beeswax-treated volume was artificially aged at $80^{\circ}C$ of temperature and 65% of relative humidity and then a physical and optical properties of an aged volumes was analyzed. Also, the degraded components of the beeswax samples isolated from different partitions of aged volumes was measured using a gas chromatography/mass spectroscopy (GC/MS). In results, the surface of beeswax-treated volume which is primarily affected by a main aging factors such as light, oxygen, moisture was more deteriorated than the inside of that volume. However, unlike inside of the book volume which was made from paper, the inside of beeswax-treated volume wax was also considerably deteriorated. The inside of the beeswax-treated volume is largely unaffected by the oxygen and humidity during aging due to the water repellency and the air permeation resistance of beeswax. Therefore, it is confirmed that aging factors and mechanisms in the inside of the volume are different from thats of the outside of the volume. This fact was also verified by the results of GC/MS analysis of an beeswax samples which was sampled from different partitions of aged volumes. As result as GC/MS analysis of the beeswax extracted from the outside of the aged volume, the low molecular compounds with a carbon length of $C_9-C_{20}$ (fatty acid, etc) were increased and the compounds with a carbon length of above $C_{34}$ (ester, etc) were also increased. But the compounds with a chain length of $C_{21}-C_{36}$ (hydrocarbon, alcohol, etc) were decreased. In case of the aged beeswax of inside, the low molecular compounds with a carbon length of $C_9-C_{20}$ (fatty acid, etc) and the compounds with a chain length of $C_{21}-C_{36}$ (hydrocarbon, alcohol, etc) were increased. While, the compounds with a carbon length of above $C_{34}$ (ester, etc) were decreased.

• 한국식품과학회지
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• 제22권2호
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• pp.150-154
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• 1990

취반과 살균을 단일화하는 레토르트 쌀밥 제조방법개발을 위해 원료쌀과 밥짓는 물을 소정량 함께 충전 밀봉한 후 살균온도$(110^{\circ}C,\;120^{\circ}C,\;130^{\circ}C)$ 및 포장재내 공기량(함기 ; 31ml, 반진공, 13ml, 진공; -0.7ml)을 달리하여 시험하였다. 수분 15.8%인 원료 쌀과 물의 비율을 1:1.1로 하여 레토르트 살균한 경우 쌀밥의 수분은 59.0-63.3%이었다. 내용 쌀밥의 층별 수분분포가 가장 균일한 조건은 $130^{\circ}C$ 진공포장이었고, 가열온도가 낮고 함기량이 많을수록 층별 차이는 컸다. 퍼짐도는 일반취반밥에 비하여 켰으며, 층별로는 상층이 낮았고 하층이 컸으며. 파우치내 잔존공기량이 많을수록 퍼짐도가 적었다. 층간의 차이는 가열온도가 높고 잔존공기량이 적을수록 적었다. ${\alpha}$화도는 포장방법에는 영향을 거의 받지 않았으나 살균온도가 높을수록 ${\alpha}$화도가 증가하였다. 색택은 가열온도가 높고 잔존 공기량이 적을수록 백색도가 높았으며, 가장 우수한 것은 $130^{\circ}C$ 진공포장 제품이었다. 밥알의 온전도는 함기포장인 것이 진공포장보다 월등히 높았다. 기호도는 진공포장의 경우가 색택과 퍼짐성에 있어서는 좋은 평가를 받았으나 외관에서는 밥알이 대부분 찌그러지고 떡모양이 되어 좋지 않았다. 함기포장의 정우는 색택에서 다소 불량하나 온전밥알의 유지상태가 좋아 조직감에서 좋은 평가를 받았다. 기호도 검사에서 가장 좋은 평가를 받은 것은 $130^{\circ}C$ 반진공 제품이었다.