Liu, Liufa;Tanaka, Katsumi;Hirose, Akio;Kobayashi, Kojiro F.
Proceedings of the KWS Conference
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2002.10a
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pp.570-576
/
2002
Application of the aged Inconel 718 in hydrogen environment is seriously restraint by its high hydrogen embrittlement (HE) sensitivity. m previous researches, we have suggested the possibility and applicability of the laser surface annealing (LSA) process in improving the HE resistance of this alloy. Sequentially, a study on the effects of the precipitates in the Inconel 718 on its HE sensitivity was conducted in this research. Firstly, flat bar specimens were heat-treated to obtain various kinds of precipitation microstructures concerning the ${\gamma}$" phase and the 6 phase. Hydrogen was charged into the specimen by a cathodic charging process. The loss in reduction of area (RA) caused by hydrogen charging was used to assess the HE sensitivity. The HE sensitivity of the alloy was lowered with decreasing the volume fraction of ${\gamma}$". Moreover, it was possible to increase the HE resistance of the aged alloy by dissolving the $\delta$ phase, keeping the strength at the same level as that of the common aged alloy. Thus, we concluded that both the $\delta$ phase and the ${\gamma}$" phase affected the HE sensitivity of Inconel 718. Next, two kinds of notch tensile specimens were fabricated, one kind having $\delta$ phase and the other having no $\delta$ phase. All these specimens were aged via the same aging heat treatment process. The LSA process annealed a thin layer of the notch bottom of each specimen. One specimen of each kind was charged with hydrogen by the cathodic hydrogen charging process. Loss in the notch tensile strength (NTS) caused by hydrogen was used to evaluate the HE sensitivity. It was found that while the HE sensitivity of conventionally aged Inconel 718 was decreased by the LSA process, the HE sensitivity of the $\delta$-free aged Inconel 718 could further be decreased. Therefore, for applications in hydrogen environments, it is possible to fabricate alloys with both good HE resistance and high strength by controlling the precipitation conditions, and to improve HE resistance further via applying the LSA process.
The present study investigated the effects of aging on Leydig cells of Sprague Dawley rats. Rats of 3, 6, 12 and 18 months of age were used. Testes of rat were fixed by whole body perfusion using a fixative containing 2.5% glutaraldehyde in cacodylate buffer, processed and embedded in epon-araldite. Using $1{\mu}m$ sections stained with methylene blue, qualitative and quantitative morphological studies were performed. Testis incubations were used to determine luteinizing hormone (LH; 100 ng/ml) stimulated testosterone secretory capacity per testis in vitro. Testosterone levels in the incubation medium, and testosterone and luteinizing hormone levels in serum of these four groups of rats were determined by radioimmunoassay. Morphological studies revealed that Leydig cells were more abundant in the testis interstitium at 6, 12 and 18 months when compared with 3 months. The volumes of Leydig cells per testis was significantly higher, at 6, 12 and 18 months of age than those at 3 months. The number of Leydig cells per testis was doubled at 6, 12 and 18 months of age compared with 3 months. The average volume of a Leydig cell was not significantly different between 3 and 6 months of age, however, at 12 and 18 months a significantly lower value was observed. LH-stimulated testosterone production per testis in vitro was reduced by 45% at 6 months of age compared with 3 months; a further significant reduction was observed at 12 and 18 months. Serum testosterone and LH levels were not significantly different between 3 and 6 months of age but at 12 and 18 months a significantly lower value was observed in both groups for these hormones. These results showed that signs of aging are apparent in Leydig cells of Sprague Dawley rats at 12 months of age.
How to stabilize wood against shrinking and swelling in variable atmospheric moisture conditions is important to the wood-using industry and a challenge to research. Polyethylene glycol stabilize wood by bulking the fiber. PEG also serve as a chemical seasoning agent, suppress decay in high concentrations, and have slight effect on physical properties, gluing or finishing. The study designed to determine the effect of PEG-400 on the dimensional stabilization of local hardwoods for wood carvings that could supply a greatly expanding tourist trade and making curved furniture parts, lamp stands and other decorative objects, and possible gunstock. The species examined were 6 species, Seo-Namoo (Carpinus laxiflora), Cheungcheung-Namoo (Cornus controversa), Gorosae-Namoo (Acer mono), Karae-Namoo (Juglans mandshurica), Jolcham-Namoo (Quercusserrata) and Sanbud-Namoo (Prunus sargentii), used as block of 5cm thick radially to the grain, 7cm wide tangentially, and 70cm long parallel to the wood grain. All these test piecies were conditioned above the fiber saturation point before impregnation. The stabilization effects were determined for PEG-400 treated woods in a 50 percent solution for 20 days. The following conclusions were obtained. PEG retentions increased with treating time. It was more effective to treat at 60$^{\circ}C$ than at room temperature. In degree of PEG-400 impregnation on species, Cheungcheung-Namoo havinglow specific gravity had the highest retentions, 68.77% but the lowest, 56.33% was shown in Jolcham-Namoo with high specific gravity. Specific gravity of treated wood increased considerably with effectiveness of polymer loading. The increases in specific gravity were 5.36 to 13.16 percent. The highest was Jolcham-Namoo, the lowest Karae-Namoo. On the dimensional stability, a 40 percent of effectiveness of polymer loading was just as effective as 60 percent in reduction in water absorptivity (RWA), antishrinkage efficiency (ASE) and antiswelling efficiency (AE), and from over 60 percent they increased more rapidly. Also species response varied considerably. ASE was 30.12 to 69.97 percent tangentially and 27.86 to 56.37 percent radially, AE 34.06 to 73.76 percent tangentially and 30.11 to 70.12 percent radially, and RWA 42.31 to 65.32 percent. No differences in volume swelling among the 6 species were observed. Its values were ranged from 14.98 to 19.55 percent and also increased with PEG retentions. On the mechanical properties, the strengths very much decreased with PEG-400 loadings as shown in Figure 12; that were 11.41 to 22.90 percent in compression, 21.61 to 34.35 percent in bending and 22.83 to 36.83 percent in tensile strength. PEG retention in cell wall was less than 1 percent and the most of PEG were immersed in cell lumen. Except for Korae-Namoo, effectivenesses of polymer loading were as much high as 61.58 to 75.02 percent. This is believed to be due to the effect of PEG-400 on excellant dimensional stability of treated woods.
This study was aimed to quantify the amount of carbon dioxide emissions and to suggest suitable plans which consider the carbon emission reduction in the manufacturing process of the domestic structural glued laminated timber. Field investigation on two glued laminated timber manufacturers was conducted to find out material flow input values such as raw materials, transportation, manufacturing process, and energy consumption during manufacturing process. Based on the collected data and the relevant literatures about life cycle inventory (LCI), the amount of carbon dioxide emission per unit volume was quantified. Results show that the carbon dioxide emissions for sawing, drying and laminating process are 31.0, 109.0, 94.2 kg $CO_2eq./m^3$, respectively. These results show 13% lesser amount of total carbon dioxide emissions compared with the imported glued laminated timber in Korea. Furthermore, it was decreased about 37% when the fossil fuel would be replaced with biomass fuel in drying process. Findings from this study is effectively used as the basic data on the life cycle assessment of wooden building.
The riverbed material survey is to investigate the particle size distribution, specific gravity, porosity, etc. as basic data necessary for river channel plan such as calculation of sediment transport and change of river bed. In principle, the survey spots are 1 km interval in the longitudinal direction of the river and 3 points or more in the 1 cross section. Therefore, depending on longitudinal length of the river to be investigated, the number of surveyed sites is very large, and the time and cost for the investigation are correspondingly required. This study is to compare the particle size analysis method with the volumetric method and the image analysis method in work efficiency and cost and to examine the applicability of the image analysis method. It was confirmed that the diameter of the equivalent circle converted by the image analysis method can be applied to the analysis of bed material particle size. In the gravel stream with a particle size of less than 10 cm and a large shape factor, the analytical result of the bed material by the image analysis method is accurate. However, when the shape factor decreases as the particle size increases, the error increases. In addition, analysis results of the work efficiency and cost of the volume method and the image analysis method showed a reduction of about 80%.
Background: To investigate the impact of the breast size, shape, maximum heart depth (MDH), and chest wall hypotenuse (the distance connecting middle point of the sternum and the length of lung draw on the selected transverse CT slice) on the volumetric dose to heart with whole breast irradiation (WBI) of left-sided breast cancer patients. Materials and Methods: Fifty-three patients with left-sided breast cancer undergoing adjuvant intensity-modulated radiotherapy (IMRT) were enrolled in the study. The primary breast size and shape, MHD and DCWH (chest wall hypotenuse) were contoured on radiotherapy (RT) planning CT slices. The dose data of hearts were obtained from the dose-volume histograms (DVHs). Data were analyzed by one-way analysis of variance (ANOVA), Student's t-test and linear regression analysis. Results: Breast size was independent of heart dose, whereas breast shape, MHD and DCWH were correlated with heart dose. The shapes of breasts were divided into four types, as the flap type, hemisphere type, cone type and pendulous type with heart mean dose being $491.8{\pm}234.6cGy$, $752.7{\pm}219.0cGy$, $620.2{\pm}275.7cGy$, and $666.1{\pm}238.0cGy$, respectively. The flap type of breasts shows a strong statistically reduction in heart dose, compared to others (p=0.008 for V30 of heart). DCWH and MHD were found to be the most important parameters correlating with heart dose in WBI. Conclusions: More attention should be paid to the heart dose of non-flap type patients. The MHD was found to be the most important parameter to correlate with heart dose in tangential WBI, closely followed by the DCWH, which could help radiation oncologists and physicsts evaluate heart dose and design RT plan in advance.
Purpose: To investigate the influence of exogenous p53 upregulated modulator of apoptosis (PUMA) expression on cell proliferation and apoptosis in human non-small cell lung cancer A549 cells and transplanted tumor cell growth in nude mice. Materials and Methods: A549 cells were divided into the following groups: control, non-carrier (NC), PUMA (transfected with pCEP4-(HA) 2-PUMA plasmid), DDP ($10{\mu}g/mL$ cisplatin treatment) and PUMA+DDP (transfected with pCEP4-(HA)2-PUMA plasmid and $10{\mu}g/mL$ cisplatin treatment). The MTT method was used to detect the cell survival rate. Cell apoptosis rates were measured by flow cytometry, and PUMA, Bax and Bcl-2 protein expression levels were measured by Western blotting. Results: Compared to the control group, the PUMA, DDP and PUMA+DDP groups all had significantly decreased A549 cell proliferation (p<0.01), with the largest reduction in the PUMA+DDP group. Conversely, the apoptosis rates of the three groups were significantly increased (P<0.01), and the PUMA and DDP treatments were synergistic. Moreover, Bax protein levels significantly increased (p<0.01), while Bcl-2 protein levels significantly decreased (p<0.01). Finally, both the volume and the weights of transplanted tumors were significantly reduced (p<0.01), and the inhibition ratio of the PUMA+DDP group was significantly higher than in the single DDP or PUMA groups. Conclusions: Exogenous PUMA effectively inhibited lung cancer A549 cell proliferation and transplanted tumor growth by increasing Bax protein levels and reducing Bcl-2 protein levels.
Journal of the Institute of Electronics and Information Engineers
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v.51
no.5
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pp.76-87
/
2014
Today the energy consumption of ICT networks is about 10% of the worldwide power consumption and is predicted to increase remarkably in the near future. For this reason, this paper studies energy saving strategies assuring the network-level QoS. In the strategies, the energy consumption of NIC(network interface card) on both endpoint of links decreases by selecting links and making them sleep when the total traffic volume of the IP network is lower than a threshold. In this paper, we propose a heuristic routing algorithm based on so-called delegating/delegated routers, and evaluate its characteristics using computer simulation considering network-level QoS. The selection of sleep links is determined in terms of the number of traffic paths (called min_used path) or the amount of traffics(called min_used traffic) through those kinks. To our experiment, the min_used traffic method shows a little better energy saving but the increased path length compared to the min_used path method. Those two methods have better energy saving characteristics than the random method. This paper confirms that the delegating/delegated router-based routing algorithm results in energy saving effects and sustains network-level QoS in IP networks.
Journal of the Computational Structural Engineering Institute of Korea
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v.19
no.2
s.72
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pp.195-202
/
2006
Thin-walled structures are efficiently utilized an automobiles, aircraft, satellite and ship as well as needed light weight simultaneously. This paper presents new shape of automobile hood reinforcement that rotating parts as engine, transmission are protected by thin-walled structures. The automobile hood is concerned about the resonance occurs due to the frequency of the rotating parts. The hood must be designed by supporting the stiffness of design loads and considering the natural frequencies. Hence, it is sustained the stiffness and considered the vibration by resonance. It is deep related to ride. Therefore, the topology, shape and size optimization methods are used to design the automobile hood. Topology technique is applied to determine the layout of a structural component optimum size with maximized natural frequency by volume reduction. In this research, The optimal structure layout of an inner reinforcement of an automobile hood for the natural frequency of a designated mode is obtained by using topology optimization method. The optimum size and the optimum shape are determined by PLBA(Pshenichny-Lim-Belegundu-Arora) algorithm.
The main reason of the earth global warming is $CO_2$ and the regulation about it in the whole world has been reinforced to reduce $CO_2$ emission. It is needed that we should reduce it in the process at the production of concrete generated much of $CO_2$ emission as the primary material of construction industry recognized unfriendly environment industry. Based on a concrete, this study was constructed the system to evaluate $CO_2$ emission generated in the stage of material production, transportation, manufacture and developed the program to reduce and evaluate it efficiently. As a result, most of $CO_2$ emission is generated in the stage of material and it is quantitatively evaluated $CO_2$ emission generated in the stage of materials, transportation and manufacture. Moreover, the evaluation system of the volume of $CO_2$ emission which has the friendly environment technology about reduction of $CO_2$ emission at each stage is suggested for quantitatively evaluation $CO_2$ emission generated in the process at the production of concrete and remicon production company could use it to evaluation $CO_2$ emission.
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