• Title/Summary/Keyword: Volume of distribution

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Atomization Characteristics for Various Injection Nozzle Type and Property Changes (분사노즐 형상에 따른 유화연료의 분무 미립화 및 물성)

  • Kim, Yong-Guk;Ryu, Jeong-In
    • Transactions of the Korean Society of Automotive Engineers
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    • v.18 no.4
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    • pp.62-67
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    • 2010
  • The objective of this experimental study is to verify atomization characteristics of emulsified fuel. The emulsified fuel made of adding the ultrasonic energy is analyzed with atomization characteristics and chemicophysics. As water contents within emulsified fuel and needle angle increase, SMD, viscosity and surface tension were analyzed. By measuring the distribution percentage of hydrogen volume by $^1H$-NMR spectrum, the proportion of aromatics and paraffins is analyzed and compared each other. The results of study is as follows. First, as water contents within emulsified fuel and needle angle of nozzle increases, SMD increases. Second, for the distribution percentage of hydrogen volume, the distribution percentage of aromatics is about 10% and the rest portion is paraffins.

Effect of ion-pair complexation with bile acids on the bilary excretion and systemic distribution of organic drugs

  • Shim, Chang-Koo
    • Archives of Pharmacal Research
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    • v.9 no.1
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    • pp.49-54
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    • 1986
  • Effect of sodium taurodeoxycholate (TDC) infused intravenously on the pharmacokinetics of methylene blue (MB) was studied in the rat to investigate the role of ion-pair complexation in the body on drug elimination and disposition. Distribution volume (Vd) of MB was increased significantly (p< 0.05) by TDC infusion. Considering together with the fact that apparent partition coefficient (APC) of MB between phosphate buffer (pH 7.4) and n-octanol was increased markedly by TDC, the increase in Vd seemed to be the result of decreased polarity of MB by ion-pair formation with TDC. But total body clearance (CLt) and biliary excretion clearance (CLbil) of MB were not increased significantly by TDC.

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Decrease of Distribution Volume of a Basic Drug in Rats of Experimental Renal Failure (신장해에 의한 염기성약물의 분포용적감소예와 그 기전)

  • 심창구
    • YAKHAK HOEJI
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    • v.27 no.1
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    • pp.21-28
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    • 1983
  • Distribution volume (Vd$_{ss}$ ) of a model basic drug, tetraethylammonium bromide (TEA) at a steady-state decreased sinificantly in glycerol and uranium-renal failure rats. Assuming carrier-mediated transport of TEA into tissues, the theoretical $Vd_{ss}$ of TEA decreases in an exponential way as the plasmal concentration of TEA increases. The relationship between $Vd_{ss}$ and plasma concentration of TEA in the experimental renal failure (ERF)-rats was similar. Therefore, the decrease in $Vd_{ss}$ of TEA in the ERF-rats seemed to be due to the saturation of the carrier system that are responsible for the tissue distribution of TEA, by the elevated plasma concentration of TEA in the ERF-rats. ERF was induced to rats with glycerol, folate, salicylate, uranium and gentamicin, respectively..

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A Study on the Parcel Warehouse & Distribution Center Network (소포물류센터 네트워크 구축에 관한 연구)

  • Noh, Seung-J.;Rim, Suk-Chul;Hong, Min-Sun
    • IE interfaces
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    • v.16 no.4
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    • pp.411-420
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    • 2003
  • This paper deals with how Korea Post establishes a nation wide network of the parcel warehouse & distribution centers(PWDC). The state-of-the-art of the parcel service business in Japan and U.S. are introduced for benchmarking purpose. Potential customers of the PWDC and their major goods are identified. Current major customers of the Korea Post were interviewed to figure out the potential demand of the PWDC service. Five-year volume estimation of the Korea Parcel Service(KPS) is presented based on the past 30-month B-C volume of the four major door-to-door delivery service companies in Korea. Yearly construction plan of the PWDCs is proposed; and the networking strategy of PWDC is discussed.

Volume Transport through the La-Perouse (Soya) Strait between the East Sea (Sea of Japan) and the Sea of Okhotsk

  • Saveliev Aleksandr Vladimirovich;Danchenkov Mikhail Alekseevich;Hong Gi-Hoon
    • Ocean and Polar Research
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    • v.24 no.2
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    • pp.147-152
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    • 2002
  • Seasonal and interannual variation of volume transport through the La-Perouse Strait were estimated using the difference of sea level observed at Krillion of Sakhalin, Russia, and Wakkanai of Hokkaido, Japan, during the period of 1975-1988. Historical sea level measurements between Russian and Japanese tide gauge data were normalized using an independent direct volume transport measurement. Volume transport from the East Sea (Sea of Japan) to the Sea of Okhotsk varied from -0.01 to 1.18 Sv with an annual mean value of 0.61 Sv. Monthly water transport rates showed a unimodal distribution with its maximum occurring in summer (August) and minimum in winter (December-February). The annual mean volume transport varied from 0.2 to 0.8 Sv during the period of 1975-1988 with the maximum variance of 0.6 Sv.

HARMONIC MORPHISMS AND STABLE MINIMAL SUBMANIFOLDS

  • Choi, Gundon;Yun, Gabjin
    • Korean Journal of Mathematics
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    • v.14 no.1
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    • pp.13-33
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    • 2006
  • In this article, we study the relations of horizontally conformal maps and harmonic morphisms with the stability of minimal fibers. Let ${\varphi}:(M^n,g){\rightarrow}(N^m,h)$ be a horizontally conformal submersion. There is a tensor T measuring minimality or totally geodesics of fibers of ${\varphi}$. We prove that if T is parallel and the horizontal distribution is integrable, then any minimal fiber of ${\varphi}$ is volume-stable. As a corollary, we obtain that any fiber of a submersive harmonic morphism whose fibers are totally geodesics and the horizontal distribution is integrable is volume-stable. As a consequence, we obtain if ${\varphi}:(M^n,g){\rightarrow}(N^2,h)$ is a submersive harmonic morphism of minimal fibers from a compact Riemannian manifold M into a surface N, T is parallel and the horizontal distribution is integrable, then ${\varphi}$ is energy-stable.

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Analysis of buckling response of functionally graded sandwich plates using a refined shear deformation theory

  • Abdelhak, Z.;Hadji, L.;Khelifa, Z.;Hassaine Daouadji, T.;Adda Bedia, E.A.
    • Wind and Structures
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    • v.22 no.3
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    • pp.291-305
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    • 2016
  • In this paper, a refined shear deformation plate theory which eliminates the use of a shear correction factor was presented for FG sandwich plates composed of FG face sheets and an isotropic homogeneous core. The theory accounts for parabolic distribution of the transverse shear strains and satisfies the zero traction boundary conditions on the surfaces of the plate. The mechanical properties of the plate are assumed to vary continuously in the thickness direction by a simple power-law distribution in terms of the volume fractions of the constituents. Based on the present refined shear deformation plate theory, the governing equations of equilibrium are derived from the principle of virtual displacements. Numerical illustrations concern buckling behavior of FG sandwiches plates with Metal-Ceramic composition. Parametric studies are performed for varying ceramic volume fraction, volume fraction profiles, Boundary condition, and length to thickness ratios. The accuracy of the present solutions is verified by comparing the obtained results with the existing solutions.

A new hyperbolic shear deformation plate theory for static analysis of FGM plate based on neutral surface position

  • Merazi, M.;Hadji, L.;Daouadji, T.H.;Tounsi, Abdelouahed;Adda Bedia, E.A.
    • Geomechanics and Engineering
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    • v.8 no.3
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    • pp.305-321
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    • 2015
  • In this paper, a new hyperbolic shear deformation plate theory based on neutral surface position is developed for the static analysis of functionally graded plates (FGPs). The theory accounts for hyperbolic distribution of the transverse shear strains and satisfies the zero traction boundary conditions on the surfaces of the beam without using shear correction factors. The neutral surface position for a functionally graded plate which its material properties vary in the thickness direction is determined. The mechanical properties of the plate are assumed to vary continuously in the thickness direction by a simple power-law distribution in terms of the volume fractions of the constituents. Based on the present new hyperbolic shear deformation plate theory and the neutral surface concept, the governing equations of equilibrium are derived from the principle of virtual displacements. Numerical illustrations concern flexural behavior of FG plates with Metal-Ceramic composition. Parametric studies are performed for varying ceramic volume fraction, volume fraction profiles, aspect ratios and length to thickness ratios. The accuracy of the present solutions is verified by comparing the obtained results with the existing solutions.

5% Rule Disclosure and Stock Trading Volume : Evidence from Korea

  • KIM, Eung-Gil;KIM, Sook-Min
    • The Journal of Asian Finance, Economics and Business
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    • v.6 no.4
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    • pp.297-307
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    • 2019
  • Despite the fact that the implementation of 5% rule is widely recognized to enhance the transparency of capital market and fairness of corporate governance market, a few evidences present information effect of 5% rule. Using 7,088 non-financial firm-year observations listed on the Korea Stock Exchange from 2006 to 2012, we analyze the relation between trading volume and 5% rule disclosure. The results show that the daily and abnormal trading volume is increased when 5% rule disclosure is released. Moreover, the trading volume is significantly increased during cooling period. Specifically, trading volume is significantly greater when one day before cooling period or the expiration day of cooling period. We also find the information effect of firms with stable ownership structure before 5% rule disclosure is relatively smaller than the firms with unstable ownership structure with unstable ownership structure. These results imply that capital market participants use the information from 5% rule disclosure and reflect in their real economic decision.

Characteristics of SMD and Volume Flux of Two-phase Jet Injected into Cross-flow with Various Gas-liquid Ratio and Reynolds Number (횡단 유동장의 기액비 및 레이놀즈수 변화에 따른 외부혼합형 이상유체 제트의 액적크기 및 체적유속 특성)

  • Kim, Jong-Hyun;Lee, Bong-Soo;Koo, Ja-Ye
    • Transactions of the Korean Society of Automotive Engineers
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    • v.17 no.2
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    • pp.75-81
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    • 2009
  • A study was performed to investigate the characteristics of two-phase jet injected into subsonic cross-flow using the external mixed gas blast two-phase nozzle. The shadowgraph method was adopted for the cross-flow jet visualization and PDPA system was used to measure droplet size, velocity, and volume flux. The atomization of two-phase jet is initially determined according to gas to liquid mass flow-rate ratio and the Reynolds number of cross-flows. The highest penetration trajectories of two-phase jet injected into cross-flow are governed by the momentum ratio at subsonic cross-flow. As GLR of two-phase jet injected into cross-flow increases, the droplet size decreases and the distribution area of volume flux increases. The distribution of volume flux that influenced by the counter vortex pair at the downstream of cross-flow is symmetric in shape of horseshoe.