• 핵의학기술
• /
• 제19권2호
• /
• pp.68-73
• /
• 2015

PET/CT 검사 시 검사 부위에 따라 적절한 액세서리의 사용이 권고되고 있다. 그 중 brain 검사에서 사용되는 액세서리인 brain holder를 사용하지 않는 경우 CT의 small FOV에 의하여 whole pallet이 AC-CT에 cover되지 않으며, 이에 따른 truncated region에 따라 count loss가 발생된다. 본 논문에서는 brain holder를 사용하지 않았을 경우 발생하는 truncated region에 의한 image quality의 변화를 평가하고자 한다. Siemens사의 biograph truepoint40 장비와 $^{68}Ge$-uniform phantom을 사용하여 $^{68}Ge$ phantom을 pallet위에서 스캔하고 brain holder위에 위치하고 스캔 하였다. brain protocol을 적용하여 holder를 사용하지 않은 경우 pallet이 AC-CT의 FOV에 포함되지 않는 것을 알 수 있었다. 획득된 영상을 FBP, OSEM, TrueX recon method를 이용하여 iteration 4, subsets 21, gaussian 2 mm와 5 mm parameter를 적용하여 재구성 후 Window level : -4200, window width : 1000으로 설정하여 영상의 uniformity를 평가하였으며, vertical profile을 생성하여 count uniformity를 평가하였고, 마지막으로 5장과 20장의 slice를 summation하여 integral uniformity를 평가하였다. AC-CT영상을 통하여 holder를 사용하지 않는 경우 FOV내에 pallet이 모두 포함되지 않는 것을 알 수 있으며, 이에 따른 truncation에 의한 부정확한 attenuation factor가 나타났다 PET corrected sinogram 영상에서 holder를 사용하지 않은 경우 truncated region에 의한 defect 부위를 확인할 수 있으며, holder를 사용한 경우 uniform한 영상을 확인할 수 있었다. Window level : 4200, window width : 1000으로 설정 시 FBP, OSEM, TrueX recon 방법 모두에서 holder를 사용한 경우 uniform한 영상이 획득되었지만, holder를 사용하지 않은 경우 하단에 defect가 관찰되었다. Holder를 사용한 경우와 사용하지 않은 경우의 영상을 각 5장, 20장씩 summation하여 NEMA method에 따라 integral uniformity를 구하였으며, 5장 slice의 summation에서 holder를 사용하지 않은 경우 11.7% holder를 사용한 경우 7.2%로 나타났다. 20장 slice의 summation에서 holder를 사용하지 않은 경우 11.1% holder를 사용한 경우 76.7%로 나타났다. brain 검사 시 holder를 사용하지 않는 경우 truncated region에 따른 phantom 하단부의 count defect가 확인되었으며, 이는 환자 검사 시 occipital lobe의 count loss를 발생하게 되며 research 검사 시 검사 결과의 오차를 발생하게 됨으로 brain PET/CT 검사 시 정확한 검사결과를 위하여 검사 액세서리가 반드시 적용되어야 할 것이다.

• 대한안과학회지
• /
• 제54권9호
• /
• pp.1445-1451
• /
• 2013

목적: 당뇨병유두병증에서 유리체강내 베바시주맙 주입술 후 망막신경섬유층 두께 변화를 장기간 측정한 2예를 보고하고자 한다. 증례요약: 36세 당뇨환자가 우안 시력저하(20/200)로 내원하였고 안저검사상 양안 시신경유두부종이 관찰되었다. 스펙트럼영역 빛간섭단층촬영기로 측정한 우안의 망막신경섬유층 두께 $278{\mu}m$로 증가 소견, 시야검사상 우안 코쪽에 국소적인 협착을 보였다. 우안 베바시주맙 주입술을 하였고 3주 후 두께는 $135{\mu}m$로 감소했으며 시력도 20/25로 호전되었으나, 좌안 시력저하(20/32)와 망막신경섬유층 두께가 $207{\mu}m$로 증가하였다. 좌안 베바시주맙 주입술을 하였고, 3주 후 두께는 $147{\mu}m$로 감소했고 시력도 20/20으로 호전되었다. 이 후 점차적으로 양안 망막신경섬유층 두께는 감소하였고, 1년 후 검사에서 우안 $87{\mu}m$, 좌안 $109{\mu}m$였다. 57세 당뇨환자가 우안 시력저하(20/200)로 내원하였고 우안의 시신경유두부종과 망막신경섬유층의 두께가 $252{\mu}m$로 증가된 소견 및 시야검사상 맹점확대를 보였다. 우안 베바시주맙 주입술 3주 후 두께는 $136{\mu}m$로 감소했고 시력은 20/70으로 호전되었으며, 3개월 후 $104{\mu}m$, 6개월에는 $83{\mu}m$로 감소했다. 결론: 본 증례에서 유리체강내 베바시주맙 주입술 후 3주내 시력의 상승과 스펙트럼영역 빛간섭단층촬영기를 통한 1년간 평균 망막신경섬유층 두께의 감소를 확인할 수 있었다.

• 사상체질의학회지
• /
• 제18권2호
• /
• pp.139-147
• /
• 2006

1. Objectives Creutzfelt Jacob Disease is one of a group of neurodegenerative disorders causing spongiform encephalopathies due to a infection of prion or unconventional slow virus on central nerve system. The diagnosis of this disease is not easy and there is currently no cure. This article is to report our case about a female patient who was not diagnosed as CJD at the early period so that we treated her with Yangkyuksanhwa-tang(凉膈散火湯) and Jihwangbaekho-tang(地黃白虎湯). 2. Methods Magnetic resonance imaging(brain MRI), blood test and computer tomography were performed. The treatment for this patient was clinically based on Sasang Constitutional Medicine. 3. Results and Conclusions (1) Visual field defect, ataxia, myoclonus, sweating and dysuria were the main symptoms of the patient. (2) The pathological change in parenchyme was not revealed during the early periods by MR imaging. So the diagnosing CJD was not possible during the time in this case. (3) Jihwangbaekho-tang(地黃白虎湯) improved her myoclonus and sweating. Bur her mental disorder and the progress of the pathological change in the parenchyme was not able to be treated.

• Journal of Korean Neurosurgical Society
• /
• 제44권4호
• /
• pp.234-239
• /
• 2008

Objective : There are a few reports on the complications of surgery for epilepsy. We surveyed our data to present complications of epilepsy surgeries from the neurosurgeon's point of view and compare our results with other previous reports. Methods : A total of 179 surgical procedures for intractable epilepsy (41 diagnostic, 138 therapeutic) were performed in 92 consecutive patients (10 adults, 82 children) during the last 9.2 years (February. 1997-April. 2006). Their medical records and radiological findings were reviewed to identify and analyze the surgical complications. Results : The diagnostic procedures encompassed various combinations of subdural grid, subdural strips, and depth electrodes. Four minor transient complications developed in 41 diagnostic procedures (4/41=9.8%). A total of 138 therapeutic procedures included 28 anterior temporal lobectomies, 21 other lobectomies, 6 lesionectomies, 21 topectomies, 13 callosotomies, 20 vagus nerve stimulations, 13 multiple subpial transections, and 16 hemispherectomies. Twenty-six complications developed in therapeutic procedures (26/138=18.8%). Out of the 26 complications, 21 complications were transient and reversible (minor; 21/138=15.2%), and 5 were serious complications (major; 5/138=3.6%). Five major complications were one visual field defect, two mortality cases and two vegetative states. There were 2 additional mortality cases which were not related to the surgery itself. Conclusion : Our results indicate that complication rate was higher than previous other reports in minor complications and was comparable in major complications. However, our results show relatively high frequency of mortality cases and severe morbidity case compared to other previous reports. The authors would like to emphasize the importance of acute postoperative care in young pediatric patients as well as meticulous surgical techniques to reduce morbidity and mortality in epilepsy surgery.

• Radiation Oncology Journal
• /
• 제8권2호
• /
• pp.163-167
• /
• 1990

1984년 부터 1989년까지 뇌하수체 선종환자 22명이 수술 및 방사선 치료를 받았다. 11개월에서 98개월간에 걸친 추적관찰 기간동안 22명중 18명($81.8\%$)의 환자에서 증상의 호전, 호르몬 감소, 또는 종양크기의 감소를 보였다. 시력감소를 보였던 환자 11명중 10명($91\%$)이 시력회복을 보였고 시야결손을 보인 12명의 환자에서 11명($92\%$)의 시야가 회복 또는 정상화 되었다. 이상에서 우리는 다음과 같은 결론을 얻었다. (1) 수술후 뇌하수체선종에 의한 증상 및 징후의 조절에 방사선치료가 유효하다. (2) 거대선종에 있어서 터어키안 위로 2 cm 이상인것과 2 cm 이하인 것의 치료효과에 있어서 통계학적 의의는 없었다.

• Structural Monitoring and Maintenance
• /
• 제2권1호
• /
• pp.19-34
• /
• 2015

One of the main causes of a limited use of nondestructive evaluation (NDE) technologies in bridge deck assessment is the speed of data collection and analysis. The paper describes development and implementation of the RABIT (Robotics Assisted Bridge Inspection Tool) for data collection using multiple NDE technologies. The system is designed to characterize three most common deterioration types in concrete bridge decks: rebar corrosion, delamination, and concrete degradation. It implements four NDE technologies: electrical resistivity (ER), impact echo (IE), ground-penetrating radar (GPR), and ultrasonic surface waves (USW) method. The technologies are used in a complementary way to enhance the interpretation. In addition, the system utilizes advanced vision to complement traditional visual inspection. Finally, the RABIT collects data at a significantly higher speed than it is done using traditional NDE equipment. The robotic system is complemented by an advanced data interpretation. The associated platform for the enhanced interpretation of condition assessment in concrete bridge decks utilizes data integration, fusion, and deterioration and defect visualization. This paper concentrates on the validation and field implementation of two NDE technologies. The first one is IE used in the delamination detection and characterization, while the second one is the USW method used in the assessment of concrete quality. The validation of performance of the two methods was conducted on a 9 m long and 3.6 m wide fabricated bridge structure with numerous artificial defects embedded in the deck.

• Journal of Korean Neurosurgical Society
• /
• 제46권4호
• /
• pp.365-369
• /
• 2009

Objective : Susceptibility-weighted image (SWI) is a sensitive magnetic resonance image (MRI) technique to detect cerebral microbleeds (MBLs). which would not be detected by conventional MRI. We performed SWI to detect MBLs and investigated its usefulness in the evaluation of mild traumatic brain injury (MTBI) patients. Methods : From December 2006 to June 2007, twenty-one MTBI patients without any parenchymal hemorrhage on conventional MRI were selected. Forty-two patients without trauma were selected for control group. According to the presence of MBLs, we divided the MTBI group into MBLs positive [SWI (+)] and negative [SWI (-)] group. Regional distribution of MBLs and clinical factors were compared between groups. Results : Fifty-one MBLs appeared in 16 patients of SWI (+) group and 16 MBLs in 10 patients of control group [control (+)], respectively. In SWI (+) group, MBLs were located more frequently in white matters than in deep nucleus different from the control (+) group (p<0.05). Nine patients (56.3%) of SW (+) group had various neurological deficits (disorientation in 4, visual field defect in 2, hearing difficulty in 2 and Parkinson syndrome in 1). Initial Glasgow Coma Scale (GCS)/mean Glasgow Outcome Scale (GOS) were $13.9{\pm}1.5/4.7{\pm}0.8$ and $15.0{\pm}0.0/5.0{\pm}0.0$ in SWI (+) and SWI (-) groups, respectively (p<0.05). Conclusion : Traumatic cerebral MBLs showed characteristic regional distribution, and seemed to have an importance on the initial neurological status and the prognosis. SWI is useful for detection of traumatic cerebral MBLs, and can provide etiologic evidences for some post-traumatic neurologic deficits which were unexplainable with conventional MRI.

• 한국산학기술학회논문지
• /
• 제15권10호
• /
• pp.6282-6288
• /
• 2014

본 논문은 용접 산업현장에서 많이 사용 되는 $CO_2$ 용접에서는 차량내부 및 탱크내부 용접에서 제어 패널을 볼 수 없는 곳, 작업장이 먼 곳 등에서 용접사가 용접을 하면서 용접조건에 맞는 전류와 전압을 조절할 수가 없고, 전류와 전압을 조절하기 위해 용접을 중단하고 잦은 이동으로 용접 구조물의 순간적인 냉각에 의해 용접결함이 발생된다. 본 연구에서는 기존의 $CO_2$ 용접기 3종류를 각각 사용하여 원격제어 토치의 용접에 대해 SS400 용접구조용 압연강재를 사용하여 원격제어 토치와 기존 $CO_2$ 용접 토치를 V형 맞대기 수직자세로 용접실험을 실시하고 용접 부의 표면비드 상태의 형상을 육안검사 관찰하고 또한 이를 침투탐상검사 및 굽힘 시험을 통해 용접부의 외관품질에 대하여 중점적으로 수행하여 용접결함 감소 및 기존 상용용접기에 교체사용에 대한 성능 및 호환성여부에 미치는 영향에 대해 평가하였다.

• 대한한방내과학회지
• /
• 제42권5호
• /
• pp.939-948
• /
• 2021

Objectives: This study considered the effectiveness of Korean medicine for the treatment of eyelid edema post craniotomy. Methods: The patient was diagnosed with Taeumin-one of the four constitution types in Korean medicine-and treated with herbal medicines: Cheongsimyeunja-tang, Chungpyesagan-tang, and Hwangryunhaedok-tang pharmacoacupuncture treatment. The severity of eyelid edema was assessed using Kara and Gokalan's scale, daily imaging of the patient's eyelids, and the ratio of the length of the left eye to that of the right. Results: Following treatment, the Kara and Gokalan score decreased from 3 to 0. The changes in the ratios were 29% and 50%, respectively. The visual field defect due to edema in the left eye was also repaired. Conclusion: This study suggests that Korean medical treatment could be an effective option for treating eyelid edema following craniotomy.

• 대한건축학회논문집:계획계
• /
• 제36권4호
• /
• pp.71-81
• /
• 2020

The purpose of this study is to propose the planning methods for pollution prevention in the initial design stage by identifying the pollution phenomena on the exterior of the building. It is important to catch the problem early on because exterior troubles begin with an initial design defect and causes rapid aging. The scope of this study is seoul public borough offices that should be sustainable for long as landmark located at the center of the district. Field survey was conducted three times in six months. Twenty-six borough offices were diagnosed with three levels of contamination through visual inspection and the contaminated locations, types, materials, and characteristics were checked. Fourteen common contaminated locations were identified in the first and intensively rechecked in the second. Five locations vulnerable to contamination were designated and the contamination and cleanliness situations were checked by location in the third. As a result, main polluted types and locations are sloping wall, upper wall, protruded wall, canopy, and wall under window. The key to avoiding these pollution problems is to minimize the horizontal plane on which dust can be deposited. In other words, it can be considered variously by shape and location, such as the slope of the horizontal plane, the floating of the surface, the installation of the roof surface, and the vertical louvers. And throating plans and material plans suitable for each location are presented. Various methods of the shape and location, material are expected to use as useful basic data for preventing pollutions during the initial design stage.