• Title/Summary/Keyword: Virtual Design Modeling

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Facile Docking and Scoring Studies of Carborane Ligands with Estrogen Receptor

  • Ok, Kiwon;Jung, Yong Woo;Jee, Jun-Goo;Byun, Youngjoo
    • Bulletin of the Korean Chemical Society
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    • v.34 no.4
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    • pp.1051-1054
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    • 2013
  • Closo-carborane has been considered as an efficient boron-carrier for boron neutron capture therapy (BNCT) and an attractive surrogate of lipophilic phenyl or cyclohexyl ring in drug design. Despite a great number of carborane-containing ligands have been synthesized and evaluated, molecular modeling studies of carborane ligands with macromolecules have been rarely reported. We herein describe a facile docking and scoring-function strategy of 16 carborane ligands with an estrogen receptor by using the commercial Gaussian, Chem3D Pro and Discovery Studio (DS) computational programs. Docked poses of the carborane ligands in silico exhibited similar binding modes to that of the crystal ligand in the active site of estrogen receptor. Score analysis of the best docked pose for each ligand indicated that the Ligscore1 and the Dockscore have a moderate correlation with in vitro biological activity. This is the first report on the scoring-correlation studies of carborane ligands with macromolecules. The integrated Gaussian-DS approach has a potential application for virtual screening, De novo design, and optimization of carborane ligands in medicinal chemistry.

Development of virtual upcycling fashion design based on 3-dimensional digital clothing technology (디지털 클로딩 기술 기반 가상착의 업사이클링 패션디자인)

  • Chen, Tianyi;Yang, Eun Kyoung;Lee, Younhee
    • The Research Journal of the Costume Culture
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    • v.29 no.3
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    • pp.374-387
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    • 2021
  • The purpose of this study is to develop up-cycling fashion design methods centered on discarded denim material for the study of original up-cycling design methods. Up-cycling fashion design work was developed using digital clothing technology. This is a recent hot topic among sustainable fashion design methods. Up-cycling fashion design expression methods (categorized as dismantlement, collages, dépaysement, grafting, weaving, and tearing) were centered on design methods. These methods create various three-dimensional modeling effects in planar forms, whereby five pieces can be applied to the fabric and digitally produced. The results are as follows: First, the use of discarded denim fabric for the development of up-cycling fashion design pieces enabled the recycling of existing resources, provided solutions to environmental pollution problems, and provided expansion opportunities for design processes for sustainable fashion products that expand the design value of denim products and their utility. Second, new eco-friendly fashion designs that attempt to achieve diversity in modern fashion trends could be presented through formative contemporary fashion produced by up-cycling work products. Third, up-cycling fashion design work is expected to provide opportunities for eco-friendly fashion design methods. This will expand the value of sustainable fashion design by recycling simple waste materials through the use of three-dimensional digital clothing technology and further through the presentation of expanded life cycles that extend product planning, production, and life cycles.

A Human Sensibility Ergonomics Method for Vehicle Driving Simulator and Verbal Expressions Collected (자동차 주행 시뮬레이터의 운동감 재현 및 감성평가를 위한 감성어휘의 수집)

  • Jeong, Yeong-Hun;Eom, Seong-Suk;Son, Gwon;Choe, Gyeong-Hyeon
    • Journal of the Ergonomics Society of Korea
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    • v.19 no.2
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    • pp.1-14
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    • 2000
  • Driving simulators have been developed for evaluating users' reaction to various driving situations. Dynamic simulators have, however, limitations of the motion feedback in space. Therefore, this paper presents a driving simulator and suggests a human sensibility ergonomics (kansei engineering) method to be used in improving sense of motion through a vehicle simulator. Human sensibility ergonomics(kansei engineering) is defined as translating technology of the customer' feeling about a new product into design elements. Constituents of the simulator were defined and the virtual world was generated by the object modeling technique. Senses perceived were classified into feelings of velocity, acceleration, rotation, and vibration based on the human sensibility associated with driving. And the most frequent verbal expressions were collected from 17 male subjects to define complex human sensibility.

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Evaluation of the Inputs Efficiency for the Interior Noise of the Vehicle using Vector Synthesis Method (벡터합성법을 이용한 차량 실내소음의 입력원 영향도 평가)

  • Yang, In-Hyung;Jeong, Jae-Eun;Oh, Jae-Eung
    • Transactions of the Korean Society for Noise and Vibration Engineering
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    • v.20 no.6
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    • pp.562-567
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    • 2010
  • A passenger vehicle has various and complicated transmission paths of sound and vibration. In order to identify the mechanism of transfer path, estimation of excitation force and exact modeling of transfer path are required. In this paper vector synthesis technique is employed to identify the characteristics of road noise and its transmission to vehicle compartment through noise and vibration analysis. Vibration reduction efficiency of each transfer path is evaluated by comparing individual vector components obtained virtual simulation. The degree of effect is used to estimate the contribution of vibration input components to total output. And in this paper presents a new technique based on simulation studies using vector synthesis diagram and design of experiments, by which the effects of magnitude and phase change of input paths can be predicted.

Design of 3-Dimensional Remote Monitoring System Using Telephone Line and Internet (전화선자 인터텟을 이용한 3차원 원격 모니터링 시스템의 설계)

  • 양필수;김주환;김성호
    • 제어로봇시스템학회:학술대회논문집
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    • 2000.10a
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    • pp.47-47
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    • 2000
  • Most measuring devices are equipped with RS-232 or GPIB interface for communicating data with computers. If the measuring devices can be accessed by a server computer, the valuable information from the devices can be effectively shared with other computers via internet. But, if the measuring devices and the server computer are too far away, it is difficulty to directly connect them by RS232 interface. PSTN(Public Switched Telephone Network) refers to the world's collection of interconnected voice-oriented public telephone networks. Measuring computer system which is equipped with RS232 interface and modem for PSTN can be introduced to overcome the aforementioned distance problem, In this work, an internet based remote monitoring system which utilizes PSTN and VRML for 3-dimensional GUI is proposed.

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Flexible Multibody Dynamic Model of a Maglev Vehicle Bogie (자기부상열차 대차 유연 다물체 모델)

  • Kim, Ki-Jung;Han, Hyung-Suk;Lee, Nam-Jin;Kim, Bong-Sub
    • Proceedings of the KSR Conference
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    • 2009.05a
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    • pp.1207-1212
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    • 2009
  • The flexible multibody dynamic model of an EMS-type Maglev vehicle is necessary in design stage to predict its behavior, load history and levitation performance. Especially in EMS-type Maglev vehicle, the body flexibility of its bogie with electromagnets affects the levitation performance because its feedback control system is more sensitive to vibration of bogie structure. The flexible multibody dynamic model of a 1/2 Maglev vehicle under test is presented. The basic modeling procedure is almost the same as in other applications. However, the feedback control system model unique in EMS-type maglev vehicle must be included in the model. With the model proposed in this study, the dynamic behavior, load history and levitation performance are more precisely predicted. This model could realize the virtual prototyping in EMS-type Maglev vehicle area.

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Design of Cyber World Tour System by VRML & XML (VRML과 XML을 이용한 가상 세계여행 시스템의 설계)

  • 이강현;오영갑;최성
    • Proceedings of the KAIS Fall Conference
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    • 2000.10a
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    • pp.280-284
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    • 2000
  • 최근에 많이 소개되는 인터넷을 이용한 교육, 학습의 대부분은 텍스트를 기반으로 하고 이미지를 삽입하는 방식을 이용하여 이루어지고 있다. 이런 방식은 인문, 사회분야의 과목에는 충분한 효과를 기대할 수 있지만 화학, 물리 등의 자연과학 과목에는 충분한 효과를 기대하기 어렵다. 이제는 통신의 발달로 인해 네트워크 사용이 생활화됨으로써 더 이상 VRML(Virtual Reality Modeling Language)이 넷스케이프 네비게이터나 마이크로소프트 인터넷 익스플로러 같은 인터넷 브라우저상에서 3차원 오브젝트만을 보여주는 시기는 지났다. 가상 세계여행 시스템은 최근 급속도로 확장되고 있는 인터넷과 인터넷 응용기술인 VRML, XML(extensible Makeup Language)을 이용하여 아직까지 사진이나 영상으로만 볼 수 있었던 세계의 도시, 건축물에 대한 정보를 3차원으로 구성된 세계여행을 통해 현실감 있는 정보를 제공하기 위해 설계되었다. 시스템의 특징은 세계의 대도시 및 유명 건축물을 VRML과 XML을 이용하여 가상으로 구성하고, 사용자는 프로그램 내에서 자신이 선택한 아바타를 조종하여 그 도시들을 여행함으로써 가상 공간 내에서 세계여행을 할 수 있다는 것이다. 또한 사용자는 여행중인 다른 아바타와의 채팅이 가능하고 도우미 아바타에게 궁금한 점을 질문할 수도 있다.

An Implementation of Hybrid-Simulation in Manufacturing Environments using Object-Oriented Methodology (객체지향 기법을 이용한 공장운용 환경 하에서의 혼합시뮬레이션 구현)

  • 김성식
    • Journal of the Korea Society for Simulation
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    • v.7 no.1
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    • pp.15-26
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    • 1998
  • In building a shell-based FMS, which is known as one of the top-down approaches in the field of factory automation, we may take a hybrid simulation into consideration. The modeling of a hybrid simulation consists of real physical entities, virtual simulation, and central clock algorithm, etc. to carry out the whole system operation. In this paper, we sow a way to construct a hybrid simulation software system in manufacturing environments. We bring in the object-oriented methodology in system design and it can contribute in dealing with a wide variety of production types and configurations. Some classes such as project, product, process, order, schedule, stage are defined. These are used and tested by implementing a specific LSI circuit assembly line process.

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DEVS-based Digital Twin Simulation Environment Modeling for Alternative Route Selection in Emergency Situations of Unnamed Aerial Vehicles (무인비행체의 유사시 대안 경로 선택을 위한 DEVS 기반 디지털 트윈 시뮬레이션 환경 모델링)

  • Kwon, Bo Seung;Jung, Sang Won;Noh, Young Dan;Lee, Jong Sik;Han, Young Shin
    • Journal of Korea Multimedia Society
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    • v.25 no.8
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    • pp.1007-1021
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    • 2022
  • Autonomous driving of unmanned aerial vehicles may have to pay expensive cost to create and switch new routes if unexpected obstacles exist or local map updates occured by the control system due to incorrect route information. Integrating digital twins into the path-following process requires more computing resources to quickly switch the wrong path to an alternative path, but it can quickly update the path during flight. In this study, we design a DEVS-based simulation environment which can modify optimized paths through short-term simulation of multi-virtual UAVs for applying digital twin concepts to path follow. Through simulation, we confirmed the possibility of increasing the mission stability of UAV.

Analysis of Lateral Behavior of Offshore Wind Turbine Monopile Foundation in Sandy Soil (사질토에 근입된 해상풍력 모노파일 기초의 횡방향 거동 분석)

  • Jang, Hwa Sup;Kim, Ho Sun;Kwak, Yeon Min;Park, Jae Hyun
    • Journal of Korean Society of Steel Construction
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    • v.25 no.4
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    • pp.421-430
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    • 2013
  • To predict behaviors of offshore wind turbines which are highly laterally loaded structures and to design them rationally, evaluating the soil-foundation interaction is important. Nowadays, there are many soil modeling methods for structural analysis of general structures subjected to vertical loads, but using the methods without any consideration for design of a monopile foundation is eschewed because it might cause wrong structural design due to the deferent loading state. In this paper, we identify the differences of the member forces and displacements by design methods. The results show that fixed end method is barely suitable for monopile design in terms of checking the serviceability because it underestimate the lateral displacement. Fixed end method and stiffness matrix method underestimate the member forces, whereas virtual fixed end method overestimates them. The results of p-y curve method and coefficient of subgrade reaction method are similar to the results of 3D soil modeling method, and 2D soil modeling method overestimates the displacement and member forces as compared with other methods.