• Architectural research
• /
• v.18 no.1
• /
• pp.1-12
• /
• 2016

This thesis explores Vitruvius and his impact upon other Renaissance architects who compare a city to a building or a building to a city, who match the city and the building into a human body, and who develop their own works. The objective of this study is to furnish an interpretation of their theory and practice through their literature and designs. In this point of view, this article takes notice of Vitruvius's six concepts coined from venustas and divides them into two parts: i.e. aesthetic quality (ordinatio, dispositio, and distributio) and technical activity (eurythmia, symmetria, and $d{\acute{e}}cor$) each. This thesis indicates that Vitruvius's successive impacts from the concepts bring about concrete design principles through proportional measurements, placing together, and hierarchic values for the former, as well as appropriate use through beautiful look, symmetrical harmony, and appropriate uses for the latter, tracking notions between a city as a house and vice versa, and either the ideas of the house or the city in the synthesis of the human body, which follows the perfect number and module based on the human body. The thesis shows that the representations of architecture and the city take place with the form of a circle and a square that express the religious belief and the cosmos, substantiating the connection between the proportions of the human body and numbers, and ultimately satisfying a concept of centrality, which is slowly extended to the enclosed plaza at the urban level from chambers, atrium, and corridors at the residence level.

• Korean Journal of Veterinary Research
• /
• v.27 no.2
• /
• pp.185-189
• /
• 1987

The number of splenic lymphocyte, serum prostaglandin $E_2$ level and natural killer cell activity were assayed after single whole body irradiation of a sublethal dose of $^{60}Co-{\gamma}$ ray to C57BL/6J mice. With a view to knowing the relationships between radiation induced prostaglandin $E_2$ level and the normal natural killer cell activity after natural killer cell-target cell conjugation, The change of normal natural killer cell activity were measured by administration of prostaglandin $E_2$ containing serum from irradiated mice. The results were summarized as follows; 1. The total number of splenic lymphocyte was significantly decreased by irradiation and the number was not affected by indometacin, prostaglandin synthesis inhibitor, treatment. 2. Serum prostaglandin $E_2$ level was increased in irradiated mice, but indometacin treated mice group showed low level of prostaglandin $E_2$. 3. In the case of irradiated mice, natural killer cell activity was not shown any difference between irradiated group and indometacin combined group. But when natural killer cell-target cell conjugations were exposed to the serum of each group during cytotoxic activity assay, whereas the normal natural killer cell activity was significantly decreased by treatment of serum from irradiated mice, the activity was not changed by treatment of indometacin pretreated mice serum. This result indicated that the prostaglandin $E_2$ induced by the radiation inhibited the post-target binding cytolytic process of natural killer activity.

• Korean Institute of Interior Design Journal
• /
• v.25 no.1
• /
• pp.115-123
• /
• 2016

In the turn of the twentieth century, Vienna emerged as a great cultural centre that stood at the forefront of developments in music, psychology, and the natural sciences. Equally influential, and still tremendously popular today, are the designs of the Wiener $Werkst{\ddot{a}}tte$ a group that was at the heart of the city's cultural scene and whose collaborators included such luminaries as the architect Josef Hoffman and the designer Koloman Moser under the slogan of Gesamtkunstwerk. The term "Gesamtkunstwerk" was introduced in the romantic period. It describes the desire for and practice of combining various art forms into a whole, such as performances that combine text, visual arts, various design and architecture. Richard Wagner was one of the early theorists of the concept, inspiring many modernist artists. As a co-founder of the Wiener $Werkst{\ddot{a}}tte$, Josef Hoffmann had a decisive influence on modern Viennese architecture and Interior design on the basis of the concept of Gesamtkunstwerk. In this view point, this study is to analyze about the generative background and design characteristics of gesamtkunstwerk advocated Wiener $Werkst{\ddot{a}}tte$. Josef Hoffmann was by all accounts a very successful architect and Interior designer in Vienna. His influence would undoubtedly have been felt simply because of his talent and energy. His special ability to range across multiple domains, coupled with a willingness to collaborate with other artists has created a synthesis and synergy that is compelling to this day.

• Korean journal of applied entomology
• /
• v.22 no.2 s.55
• /
• pp.84-97
• /
• 1983

Under the limited arable land, the enhancement of agricultural productivity is indispensable to provide the food demand which is concomitant with the rapid increase in population. From this viewpoint, the upbringing and dissemination of high-yielding varieties has been promoted continuously and several modifications in cultural practices, including heavy fertilization, dense planting, and early transplanting, also have been gradually developed. However these changes in cultivation have led to the increased outbreak of insect pests and diseases. And this unexpected results have accelerated the number and complexity of pesticides employed as well as their consumption. Even though pesticides are essential materials contributing to the steady production of agricultural crops, large scale consumption of them has given rise to several adverse impacts, such as mammalian hazard and/or environmental contamination. In this respect, recent development of new pesticides has been concentrated on 'safe pesticide', as it were, that has the highly selective properties without unfavorable side influences on other ecosystem. According to literature cited up to now, feasibilities of safe pesticide development would be summarized as two categories. One of them is the development of chemical pesticides, which include the molecular structure modification of established pesticides for increased safety and synthesis of new safe chemicals which can attack the vulnerable point of physio-ecological characteristics in insect pests and diseases. The other is the biological pesticides which comprise natural enemies and microorganisms to act selectively on confined insect pests and diseases, In addition, improvement of physico-chemical properties of available pesticide formulations would be one of the desirable means for safe pesticide development in view of efficacy enhancement and minimization of hazardous properties or safe pesticide development, various approaches are feasible and needed to study, however, long period and much financial outlay are necessary to develop a new item. And under the present situation in Korea, there are many difficulties for performing research on all the possible routes. Therefore, combined pesticides by the reasonable combination of already registered resticides evaluated as the fairly safe pesticides and safe formulation based on their physico-chemical properties would be developed primarily. And many efforts would be given gradually for the development of new chemical and biological pesticides.

• YAKHAK HOEJI
• /
• v.40 no.2
• /
• pp.218-224
• /
• 1996

This laboratory has recently reported the synthesis and in vitro antitumor activity of PT(II) complexes containing ethylenediamine and diphosphine. In view of the reports of others, cisplatin is toxic to the kidney since the kidney's vulnerability to PT(II) complexes may originate in its ability to accumulate and retain platinum to a greater degree than other organs. The in vitro cytotoxicity of these synthetic PT(II) complexes on the primary cultured proximal tubular cells of rabbit kidney and renal cortical cells of human kidney was investigated. Three endpoints for cytotoxicity tests were evaluated:3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT), $^3H$-thymidine uptake and the glucose consumption tests. The rank order of sensitivity exhibited $^3H$-thymidine uptake>MTT>glucose consumption test. The agents with diphosphine leaving group were significantly less cytotoxic than cisplatin. Moreover, 1,2-bis(diphenylphosphino)ethane (DPPE) exhibited less cytotoxicity than 1.3-bis (diphenylphosphino)propane (DPPP) against on rabbit and human cultured kidney cells. Based on these results, the decreased nephrotoxicity of these new complexes over cisplatin appeared to be partially attributable to a leaving group of DPPP and DPPE. This novel class of platinum compound represents a valuable lead in the development of a "third-generation" agent.

• Korean Institute of Interior Design Journal
• /
• no.12
• /
• pp.91-99
• /
• 1997

Alvar Aalto has pursued National Romanticism, cultural art movement in scandinavian peninsula, organic concepts of growth and suitability, comprehensive view of nature including a possibility of coexistance of human-being and the nature well harmonized. For instance, his design expressed local features of the nature, human emotions instead of geometical arts and mathematical principles. It is noteworthy today that he built up the identity with satrical architecture vocabularies, different from modern arch-itechtural idiology. The characte-ristics of his design related to interior architecture are collectively as follows; The first, Space discontinuity of the interior and exterior, gradual process by joints which are inclined to collage with many shapes in plan and section of the space and such joints are adjusted by sensual ways and stressed with inner collectivity in his works. The second, He pursued the architectural orderfor modern irreqularity, various changes and sensual harmonies. As result, free curved line, fan shape and irregular modeling were individually expressed by technics of natural features and national characteristics of Finland. The third, Organic synthesis. A harmony through med-ums in its space, materials and space effectiveness relations are made and expressed for mixed design especially harmonized of all the materials he planned, entire harmony with total design, itemized details, materials and furnitures in entire space. The fourth, The interest of the nature based on his sense harmonized with nature made him mainly use native materials, lumbers and red bricks masonry and showed and arranged various interior sky light and grazed in to let natural light in, harmony with garden to sensually cohere to the nature and courtyard, etcetera. His major subject are to direct architectural developments through the nature and human-being in his works. At this point, it is considered that his direction of the locality and independence as a human-being made the concepts of organic space structure possible.

• The Journal of the Korea Contents Association
• /
• v.14 no.12
• /
• pp.555-564
• /
• 2014

The boundary noise in image syntheses using DIBR consists of noisy pixels that are separated from foreground objects into background region. It is generated mainly by edge misalignment between the reference image and depth map or blurred edge in the reference image. Since hole areas are generally filled with neighboring pixels, boundary noise adjacent to the hole is the main cause of quality degradation in synthesized images. To solve this problem, a new boundary noise removal algorithm using a preprocessing of the depth map is proposed in this paper. The most common way to eliminate boundary noise caused by boundary misalignment is to modify depth map so that the boundary of the depth map can be matched to that of the reference image. Most conventional methods, however, show poor performances of boundary detection especially in blurred edge, because they are based on a simple boundary search algorithm which exploits signal gradient. In the proposed method, a two-step hierarchical approach for boundary detection is adopted which enables effective boundary detection between the transition and background regions. Experimental results show that the proposed method outperforms conventional ones subjectively and objectively.

• Journal of architectural history
• /
• v.19 no.2
• /
• pp.67-83
• /
• 2010

The purpose of this research is to rethink Alvar Aalto's architecture on the basis of the aesthetic concept of play. This attempt is valid because he had asserted the importance of play in his design. But more fundamentally, his critical view of the instrumentalised rationalism implied the idea that a human being is "Man the Player" as well as "Man the Thinker", of which theory was elaborated in Johan Huizinga's Homo Ludens (1938). Premised on it, this paper investigated the evolution of the play idea in aesthetics and located Aalto's concept within the map. Summing up, his play was an intuitively grasped desire opposed to a rational requirement, which leads to a dialectical synthesis. This schema is similar to that of Schiller, in which Spiel reconciles the reason and the sense. However, Aalto's play could be differentiated into the "astonishingly rational" and "a jest", each of which roughly corresponds to the Spieltrieb (play impulse) and the sinnliche Trieb (sensuous impulse) in Schiller's thinking. On the other hand, Aalto's architecture illustrates play that could be interpreted as the overflow of surplus energy. This play is the very concept that can bridge the gap in the form-function formula of modern architecture. Aalto's play idea seemed to basically originate from his personality but its value must be confirmed by the Finnish litterateur Yrjo Hirn as Aalto mentioned in his statements (1953 & 1972). It appears that Aalto's play concept was materialised in architecture through his typical design language, such as the undulating wall, the aperspective space, the imitation of nature and the collage of heterogenous elements. However, we should be careful not to reductively analyse the application of play in practise. As Huizinga's comprehensive theory suggests, the play element exists in any cultural areas including any architectural activities. In conclusion, this paper argues that Alvar Aalto the Homo Ludens presented the possibility of critical rationalism in modern architecture by imbuing dry modernism with "the life enhancing charm" of "the art of play".

• Journal of Environmental Science International
• /
• v.10 no.1
• /
• pp.65-71
• /
• 2001

HRP(high rate pond) which had kept the manufactured clay of 3cm-thickness as benthic clay in reactor and the 6 flat-blade turbine as impeller for agitation was named HRASP(high rate algae stabilization pond). And the experiment for treatment of artificial synthesis wastewater containing COD :300mg/$\ell$, NH$_3$-N : 300mg/$\ell$, T-P : 9mg/$\ell$ as nutrients was been performed successfully. This reactor was been operated under conditions : 24hrs.-irradiation and water temperature, $25^{\circ}C$ and pH 7 and agitation velocity, 15, 30, 45rpm and the effect of agitation velocity on algal bioaccumulation of nutrients was been studied with view point of fluid dynamics. The next followings could be obtained as results. 1. The agitation with a turbine impeller blade in HRASP makes clay particle indicate superior suspension effect by means of forming of excellent curl/shear flow in reactor. 2. The excessive suspension of clay particle which is created at 45rpm as rotation velocity of impeller blade of turbine disturbs the light penetration and algal photosynthesis reaction. 3. Efficiencies for removal of nutrients come out as COD : 93.9%~94.3%, ($NH_3-N + NO_3-N$) : 81.9%~99.0%, T-P : 46.8%~53.6%. 4. Kuo values of $K_1$for algal growth come out seperately as 15rpm : $1.876{\times}10^{-2}, 30rpm : 4.618{\times}10^{-3}$. 5. Kuo values of $K_2$for removal of N, P come out seperately as 15rpm : $8.403{\times}10^{-1}$ and $1.397{\times}10^{-1}$, 30rpm : $4.823{\times}10^{-1} and 2.052{\times}10^{-1}$. 6. It can be guessed easily that the excessive agitation can inhibit the algal and bacterial symbiotic reaction if it is considered that micro organism\` sense to preservation of life is relied on natural function of metabolism. Therefore the studies for this matter should be followed continuously.

• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.8
• /
• pp.3463-3471
• /
• 2015

Background: The principal aim of health service providers in the field of breast cancer is to detect and treat lesions at an appropriate time. Therefore, identification of barriers to screening can be very helpful. The present study aimed to systematically review the qualitative studies for extracting and reporting the barriers of screening for breast cancer from the womans perspective. Materials and Methods: In this systematic review; Pubmed, Google Scholar, Ovid Scopus, Cochrane Library, Iranmedex, and SID were searched using the keywords: screening barriers, cancer, qualitative studies, breast and their Persian equivalents, and the needed data were extracted and analyzed using an extraction table. To assess the quality of the studies, the Critical Appraisal Skills Programme (CASP) tool was used. Results: From 2,134 related articles that were found, 21 articles were eventually included in the study. The most important barriers from the point of view of 1,084 women were lack of knowledge, access barriers (financial, geographical, cultural), fear (of results and pain), performance of service providers, women's beliefs, procrastination of screening, embarrassment, long wait for getting an appointment, language problems, and previous negative experiences. Articles' assessment score was 68.9. Conclusions: Increasing women's knowledge, reducing the costs of screening services, cultural promotion for screening, presenting less painful methods, changing beliefs of health service providers, provision of privacy for giving service, decreasing the waiting time, and providing high quality services in a respectful manner can be effective ways to increase breast cancer screening.