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흰눈섭황금새(Muscica narcissina zanthopygia HAY)의 생태-특히 번식경과와 육령기의 식습성 (Ecological Notes on Narcissus Flycatcher, Musciapa narcissina zanthopygia HAY - With special reference to the breeding process and feeding habits of nestlings during their nesting period-)

  • 원병오;이경조
    • 한국동물학회지
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    • 제8권2호
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    • pp.89-127
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    • 1965
  • 1. This report is on the outcome of observation made up the breeding process of Narcissus flycatcher, Muscicapa narcissina zanthopygia, using 15 ness-boxes at Seoul and Kwang Nung Experimental forest in 1964, and the relevant feeding habit was studied by the collar method of wrapping the necks of thenestlings for 50-60 minutes or more in some cases from 1963 to 1964. 2. The Narcissus flycatcheris a common summer resident throughout Korea arriving at the end of April. The earliest data of arrival of this species in Seoul, is April 26, 1964. They migrate southward from the later part of September to early part of October. 3. In a week after their arrival , they start to build nest after a brief courtship. Male and female prepare their nest ina nestboxes in 4 or 5 days. Nests are usually found in the moss, which provide definite frame-work. The inner side of the nest is usually composed of roots of Gramineae or leaves of pine, oak or other broad leave tree. 4. The laying period is generally from the later part of April to the middle of June : and the number of eggs laid is from 3 to 8 , therefore 5 in average : eggs are pink with traces of milky yellow blending of light auburn and orange red spots and chicken-egg-like in shape. 5.The incubation takes place for 7-12 days from the middle part of May to the middle of June, in the order of male and female . The hatching rate tends to increase in proportion to clutch size. 6. The feeding period usually lasts 15 days in average from the early part of June to the middle of July and the feeding urge tends to increase in proportion to brood size. 7. The animals invading into their nest-boxes are red ants, chipmunks, bees , barkbeetles and philippine red-tailed shirkes, etc. 8. On the basis of analysis covering 714 birds in 31 nests, the food they consumed during the nesting period of nestlings were mostly of animal matters composing of : insect larvae form-39. 88% insect adult form 36.26%, insect pupae-0.19%, spider-17.75% and other animal matters 5.92% , Besides a small amount of plant pieces were found . As to the insect larvae, Lepidoptera was the largest in the content followed by Hymenoptera , Orthoptera and Coleoptera. As to the insect adult, Diptera was the largest in the content followed by Coleoptera, and Hymenoptera. In view of forest protection, noxious insect was of 69.38%, useful insect 4.39%, and spider 17.75%. 9. The rich assortment of its food, the ability of acquiring various insect (adults as well as larvae), its destruction of great numbers of harmful insects , and its quick assimilation artificial nesting with the nest-boxes of 2.5-3cm entrance hole employed, allow us to conclude that the flycatcher may be successfully employed in the elimination of fores pests. The above results are only that part obtained near Seoul in the middle of Korea, however, if we would extend the scheme to other broad areas using similar techniques, the nest-boxes could not only be well used by the birds, but also it would help to prevent the increase of harmful. insects.

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Genenation of structural diversity in polyketides by combinatorial biosynthesis of polyketides: Part I. Generation of multiple bioactive macrolides by hybrid modular polyketide synthases in Streptomyces venezuelae, Part II. Production of novel rifamycins by combinatorial biosynthesis

  • Yoon, Yeo-Joon
    • 한국미생물생명공학회:학술대회논문집
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    • 한국미생물생명공학회 2002년도 학술발표대회
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    • pp.18-25
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    • 2002
  • The pikromycin biosynthetic system in Streptomyces venezuleae is unique for its ability to produce two groups of antibiotics that include the 12-membered ring macrolides methymycin and neomethymycin, and the 14-membered ring macrolides narbomycin and pikromycin. The metabolic pathway also contains two post polyketide-modification enzymes, a glycosyltransferase and P450 hydroxylase that have unusually broad substrate specificities. In order to explore further the substrate flexibility of these enzymes a series of hybrid polyketide synthases were constructed and their metabolic products characterized. The plasmid-based replacement of the multifunctional protein subunits of the pikromycin PKS in S. venezuelae by the corresponding subunits from heterologous modular PKSs resulted in recombinant strains that produce both 12- and 14-membered ring macrolactones with predicted structural alterations. In all cases, novel macrolactones were produced and further modified by the DesVII glycosyltransferase and PikC hydroxylase leading to biologically active macrolide structures. These results demonstrate that hybrid PKSs in S. venezuelae can produce a multiplicity of new macrolactones that are modified further by the highly flexible DesVII glycosyltransferase and PikC hydroxylase tailoring enzymes. This work demonstrates the unique capacity of the S. venezuelae pikromycin pathway to expand the toolbox of combinatorial biosynthesis and to accelerate the creation of novel biologically active natural products. The polyketide backbone of rifamycin B is assembled through successive condensation and ${\beta}$-carbonyl processing of the extender units by the modular rifamycin PKS. The eighth module, in the RifD protein, contains nonfunctional DH domain and functional KR domain, which specify the reduction of the ${\beta}$-carbonyl group resulting in the C-21 bydroxyl of rifamycin B. A four amino acid substitution and one amino acid deletion were introduced in the putative NADPH binding motif in the proposed KR domain encoded by rifD. This strategy of mutation was based on the amino acid sequences of the corresponding motif of the KR domain of module 3 in the RifA protein, which is believed dysfunctional, so as to introduce a minimum alteration and retain the reading frame intact, yet ensure loss of function. The resulting strain produces linear polyketides, from tetraketide to octaketide, which are also produced by a rifD disrupted mutant as a consequence of premature termination of polyketide assembly. Much of the structural diversity within the polyketide superfamily of natural products is due to the ability of PKSs to vary the reduction level of every other alternate carbon atom in the backbone. Thus, the ability to introduce heterologous reductive segments such as ketoreductase (KR), dehydratase (DH), and enoylreductase (ER) into modules that naturally lack these activities would increase the power of the combinatorial biosynthetic toolbox. The dehydratase domain of module 7 of the rifamycin PKS, which is predicted to be nonfunctional in view of the sequence of the apparent active site, was replaced with its functional homolog from module 7 of rapamycin-producing polyketide synthase. The resulting mutant strain behaved like a rifC disrupted mutant, i.e., it accumulated the heptaketide intermediate and its precursors. This result points out a major difficulty we have encountered with all the Amycolatopsis mediterranei strain containing hybrid polyketide synthases: all the engineered strains prepared so far accumulate a plethora of products derived from the polyketide chain assembly intermediates as major products instead of just analogs of rifamycin B or its ansamycin precursors.

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서구 종교학의 역사에 대한 지성사적 재조명: 키펜베르크의 논의를 중심으로 (The History of the History of Religions and Intellectual History : Concerning with the Work of Hans G. Kippenberg)

  • 조현범
    • 대순사상논총
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    • 제17권
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    • pp.113-134
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    • 2004
  • According to Hans Kippenberg, the foundation of an academic study of religions coincided with the beginnings of modernization. Since the second half of the nineteenth century most European countries were involved in a process of rapid social change. The repercussions that this had for daily life were momentous. Instead of working for their traditional needs, people now had to produce goods for a market. Old customs ceded to private contracts and political laws. The superior knowledge of science replaced the inherited worldview. This deep changed severed societies from their ties to the past. Many educated people in Europe believed in an imminent end of all religions. Had not the scientific progress superseded the religious worldview? Historians had to come to terms with that expectation when they directed their attention to historical religions. Friedrich Max Muller introduced a new science, so-called Religionswissenschaft through the study of the ancient Vedic sources. He thought that genuine religion was a taste for, and sense of, the infinite. From his point of view, the Indian sources confirm that nature is more than mechanical laws. Thus his interpretation sought to contradict the materialist ideology of his day. Edward Burnett Tylor described religions as a kind of natural philosophy. His notion of 'soul' functioned to explain natural events. This legacy of the past cannot be missed even in modern society. Only the concept of the soul may preserve human dignity in an age of materialism. Gerardus van der Leeuw, also tried to perform the same function of the cultural critique for the renewal of the religious imagination in modern, rationalized Europe imprisoned in the iron-cage. In this respect, we could think that the interpretations of the history of the History of Religions in the light of the intellectual history are very suggestive for the korean student of religion. It helps them to describe the early history of the study of religion in Korea. For example, Yi Neung Wha(李能和) is regarded as 'a father of korean religious studies, but no one could present a proper answer for the question of why and through which connection of his intellectual milieu he was interested in the religious history and the study of religion. We would discover its signification in his confrontation of the prevailing social thought, such as social evolutionism.

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치과기공사의 이직에 관한 연구 (A Study on the Job Transfer of Dental Technicians)

  • 권은자;배상목
    • 대한치과기공학회지
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    • 제25권1호
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    • pp.173-185
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    • 2003
  • This study mainly intends to determine the factors for which dental technicians are satisfied with their jobs and how much the resulting job transfer rate is and thus to identify the correlation between them. For these purpose, 200 subjects were sampled out of dental technicians in Seoul and Incheon, and the survey was performed from July 19, 2002 to August 15 (for 25 days) with self-administered questionnaire. Out of all collected questionnaires, 131 pieces(65.5%) were addressed for this study. As for the tools for this study, the structured questionnaire was used with its proven reliability and feasibility, and the contents of questionnaire consisted of 32 questions on the basis of related references. The contents of questionnaire were categorized into 3 sections: General attribute of subjects; Factors for which dental technicians are satisfied with their jobs; and their intention of job transfer. The questionnaire consisted of total 32 questions which included general attribute of subjects(10 questions), factors of their satisfaction with jobs(17 questions) and intention of job transfer(5 questions). The data analysis was processed by computerized system with SPSS(Statistical Package for Social Sciences). Statistical analysis techniques included frequency, percentage, T-test, F-test analysis and regression analysis. As a result of those analyses, the conclusion can be summarized as follows: 1. As a result of analyzing the factors for which the subjects were satisfied with their jobs, it was found that there were significant differences in career and job title out of question items(P<0.001). It was also shown that the factors of subjects' satisfaction averaged 3.43, which was considerably higher value than I expected. It was found that job and management factors were major job satisfaction factors. 2. As a result of analyzing the intention of subjects to decide their job transfer, it was found that there were significant differences in job title and marital status out of question items(P<0.001). It was shown that the total average of the intention of their job transfer amounted to 3.06. It was shown that dental technicians have relatively higher intention of job transfer from their current work place. 3. It was found that there was inverse correlation between the factors of subjects' satisfaction with their jobs and their intention of job transfer(r=-0.490, P<0.05). Likewise, it was also found that there was inverse correlation mostly between the evaluation value for each independent variable region in term of each factor of job satisfaction and the value for the intention of job transfer. In view of these correlations, it was concluded that higher job satisfaction likely led to lower job transfer. 4. As a result of regression analysis so as to determine the influences of job satisfaction factors on the intention of job transfer, it was found that the highest influential factor was management factor. And it was shown that the test values of model were statistically significant and its explanatory power amounted to 54.6%.

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한의학 교육과정의 인문사회의학 교육필요성에 대한 한의사의 태도 연구 (Attitudinal Study of Korean Oriental Medical Doctors toward the Educational Necessity of Human Social Medical Study in the Curriculum of Korean Oriental Medicine)

  • 이현지;홍진우;홍승표;임영규;김동기;정재걸;이승연;권영규
    • 동의생리병리학회지
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    • 제24권6호
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    • pp.1134-1141
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    • 2010
  • The standardized education for medical college students not only provides the opportunity to get the exclusive knowledge as a professional but also is the basis of strong professional authority. Korean Oriental medicine has pursued to standardize the education system and curricula away from the traditional education system since the modernization started. And this standardization has worked as the basis of the status advancement of Korean Oriental medicine. Through the standardization of education system and curricula, Korean Oriental medicine has been professionalized and its social status has been heightened, stabilizing itself within the establishment of institution. After this, Korean Oriental medicine has kept pursuing standardization and professionalization in the educational area. It has achieved the professionalization of curricula reflecting the specificity of Korean Oriental medicine, following the model of western medical education. This paper investigated the attitude of Korean Oriental medical doctors toward the current Korean Oriental medical education. In the survey conducted in this study, how the Korean Oriental doctors view the education of Korean Oriental college in the areas such as 'standardization', 'specificity', 'Korean Oriental medical philosophy', 'responsibility', and 'professional ethics'. And the relationship between the demographic variables of Korean Oriental medical doctors and the educational contents which should be emphasized in Korean Oriental medical school has been examined. The subjects of this study were Korean Oriental medical doctors who work as professionals after graduation of Koran Oriental Medical School and, thus, this is a meaningful study in that the contents of education which the Korean Oriental medical doctors think are needed in practice are discussed.

저소득 여성가구주의 빈곤화 과정에 대한 연구 (A Study on Pauperization Process of Low-Income Woman Head of Household)

  • 정미숙
    • 한국사회복지학
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    • 제59권4호
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    • pp.191-216
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    • 2007
  • 본 연구는 가족과의 관계 속에서 형성되는 여성 빈곤의 문제, 특히 남성 생계부양자 규범에 의해 여성들이 어떻게 자원배분과 자원통제에서 배제되어 빈곤에 취약해지게 되었는지 살펴보고자 하였다. 이를 위해 이혼경험이 있는 저소득 여성가구주 10명의 생애사를 분석하였다. 저소득 여성가구주들이 빈곤층에 이르게 되기까지 빈곤경로에 있어서 차이가 있는 것으로 나타났다. 여성가구주들이 빈곤에 이르게 되는 경로에 따라서 빈곤의 지속유형과 빈곤으로의 유입유형으로 분류하였다. 여성가구주의 빈곤은 출생 가족과 결혼 후 가족에서 자원형성과 자원배분, 자원통제에서의 차별을 통해서 빈곤에 취약해졌다. 남성 생계부양자 규범은 차별기제로 작동되었으나 빈곤화 경로 유형에 따라서 그것이 작동되는 방식에서 차이가 있음을 드러내었다. 빈곤의 지속 유형 사례 여성들에게 남성 생계부양자 규범은 상징적인 힘으로 작동되면서 이 여성들의 경제활동은 가족을 보살펴야 하는 아내 역할의 차원에서 수행되었다. 반면 빈곤으로의 유입 유형 사례 여성들에게 남성 생계부양자 규범은 피부양자의 위치로 자신을 인식함으로서 직업경력 단절 및 자원통제권을 상실하게 되면서 빈곤에 취약해졌다. 이러한 연구결과는 지금까지 여성가구주로 빈곤 논의에서 전제되고 있는 통념이 허구임을 밝힘으로써, 가족(The Family)만 유지된다면 여성은 빈곤하지 않을 것이라는 기존 시각을 문제화하고 관점 전환의 필요성을 제안하고 있다는 점에서 연구의 의의를 찾을 수 있다.

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Inhalation of Bacterial Cellulose Nanofibrils Triggers an Inflammatory Response and Changes Lung Tissue Morphology of Mice

  • Silva-Carvalho, Ricardo;Silva, Joao P.;Ferreirinha, Pedro;Leitao, Alexandre F.;Andrade, Fabia K.;da Costa, Rui M. Gil;Cristelo, Cecilia;Rosa, Morsyleide F.;Vilanova, Manuel;Gama, F. Miguel
    • Toxicological Research
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    • 제35권1호
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    • pp.45-63
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    • 2019
  • In view of the growing industrial use of Bacterial cellulose (BC), and taking into account that it might become airborne and be inhaled after industrial processing, assessing its potential pulmonary toxic effects assumes high relevance. In this work, the murine model was used to assess the effects of exposure to respirable BC nanofibrils (nBC), obtained by disintegration of BC produced by Komagataeibacter hansenii. Murine bone marrow-derived macrophages ($BMM{\Phi}$) were treated with different doses of nBC (0.02 and 0.2 mg/mL, respectively 1 and $10{\mu}g$ of fibrils) in absence or presence of 0.2% Carboxymethyl Cellulose (nBCMC). Furthermore, mice were instilled intratracheally with nBC or nBCMC at different concentrations and at different time-points and analyzed up to 6 months after treatments. Microcrystaline $Avicel-plus^{(R)}$ CM 2159, a plant-derived cellulose, was used for comparison. Markers of cellular damage (lactate dehydrogenase release and total protein) and oxidative stress (hydrogen peroxidase, reduced glutathione, lipid peroxidation and glutathione peroxidase activity) as well presence of inflammatory cells were evaluated in brochoalveolar lavage (BAL) fluids. Histological analysis of lungs, heart and liver tissues was also performed. BAL analysis showed that exposure to nBCMC or CMC did not induce major alterations in the assessed markers of cell damage, oxidative stress or inflammatory cell numbers in BAL fluid over time, even following cumulative treatments. $Avicel-plus^{(R)}$ CM 2159 significantly increased LDH release, detected 3 months after 4 weekly administrations. However, histological results revealed a chronic inflammatory response and tissue alterations, being hypertrophy of pulmonary arteries (observed 3 months after nBCMC treatment) of particular concern. These histological alterations remained after 6 months in animals treated with nBC, possibly due to foreign body reaction and the organism's inability to remove the fibers. Overall, despite being a safe and biocompatible biomaterial, BC-derived nanofibrils inhalation may lead to lung pathology and pose significant health risks.

위생담당 공무원의 직무실태와 위생업무의 보건소 이관에 대한 태도 (Sanitary Officials' Affairs State and Attitude about Transfer of Sanitary Affairs Control to Health Center)

  • 손성호;감신;박재용;박기수;한창현;차병준
    • 보건행정학회지
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    • 제9권3호
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    • pp.129-148
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    • 1999
  • This study was performed to investigate contents of affairs and job satisfaction of sanitary officials at sanitary department and health center. and to assess attitude about transfer of sanitary affairs control to health center and to devise Improving program of sanitary affairs. Four-hundred and fifty-five sanitary officials were sent a postal questionnaire and eighty-four percent completed and returned the questionnaire (382 persons). The major results are as follows: The major sanitary affairs performed by sanitary officials were permission and filing of restaurant business (15.1%), supervision and regulation of that (14.4%). Sanitary officials answered that supervision and regulation of insanitary and/or subquality foods, planning of food sanitary administration, and permission and filing of restaurant business were their important affairs. They replied that the most serious problem of sanitary affairs was 'lack of contribution to the public health' (40.9%), 'putting first in supervision' (26.4%), and 'lack of personnels' ( 19.1 %), and the most important thing to improve sanitary affairs was the substantial inherent affairs. And they indicated that the agency to be desired for sanitary affairs control was the sanitary department (51.6%), the health center (25.4%), For the degree of satisfaction in affairs, 29.1% of sanitary officials felt proud, 59.6% felt overwork, 59.3% hoped transferring to other worksite and the major reason of transferring was lack of promotion opportunity in officials of sanitary department. disciplinary punishment and social corrupt view in officials at health center. The 41.1 % of sanitary officials at sanitary department didn't know that sanitary affairs had been stated as affairs of the health center in Community Health Act. After transferring affairs control to the health center, 14.4% of them felt more proud of affairs but 20.0% less proud. 23.2% more satisfactory but 22.4% more dissatisfactory. and 64.8% answered that sanitary affairs did not change. The results indicate that sanitary affairs should be changed to supervise and control insanitary and/or subquality foods, so that they play an important role at health promotion, and make sanitary officials feel proud at their own work.

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지식 상호보완성과 PMO수행체계가 IT 프로젝트 성과에 미치는 영향 (The Effect of Knowledge Complementarity and PMO Implementation System on Performance of IT Project)

  • 김충영;장지연;최규진
    • 경영과정보연구
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    • 제37권4호
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    • pp.141-156
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    • 2018
  • PMO(Project Management Office)는 IT 프로젝트의 성공적인 운영을 위한 보편적 접근방법으로 여겨지고 있다. PMO에 관한 선행연구는 PMO의 규범적 역할과 기능을 규명하는 데 집중하는 경향이 있다. 반면 실제 현장에서는 PMO가 발주기업과 전문PMO로 구성되는 조직간 협력체로서 운영되고 있기 때문에 적절한 협력체 (PMO 수행체계)의 수립은 프로젝트 성과에 의미있는 영향을 미칠 것으로 보인다. 본 연구에서는 발주기업과 외부 전문PMO의 역량이 PMO 수행체계의 수립을 통해 프로젝트 성과에 어떠한 영향을 미치는지 살펴보았다. 더불어, 발주자와 전문PMO 간의 지식 상호보완 정도에 따라 각각의 역량이 수행체계에 미치는 영향에 변화가 있는지도 살펴보았다. 연구결과, 발주기업과 외부 전문PMO의 역량이 PMO수행체계의 수립에 긍정적인 영향을 미치며 추진조직과 역할 및 책임에 대한 명확한 정의와 표준화된 프로세스의 확립 등이 IT 프로젝트의 성과에 중요한 요인임이 밝혀졌다. 또한, 발주기업과 전문PMO가 공통지식 기반을 갖고 지식 상호보완성을 확보했을 때 PMO가 더욱 효과적으로 기능을 발휘하는 것으로 밝혀졌다. 종합하면, IT 프로젝트의 성공을 위해서는 PMO 수행체계수립에서 거버넌스 관점의 접근이 중요하며 발주기업과 외부 전문 PMO 간의 지식 상호보완성의 확보가 도움이 되는 것으로 볼 수 있다.

The Knowledge Transfer of Tesco UK into Korea, in Terms of Retailer Brand Development and Handling Processes

  • Cho, Young-Sang
    • 유통과학연구
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    • 제9권2호
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    • pp.13-24
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    • 2011
  • With the increasing market share of retailer brands, many authors have paid considerable attention to retailer brands. Before market liberalisation in 1996 in Korea, retailer brand market was led by the supermarket retailing format, although the first retailer brand product was developed by the department store format. In parallel with the entry of foreign multiple retailers, the retailer brand market has experienced rapid growth. Particularly, the expansion of Tesco UK with well-established retailing know-how into Korea has encouraged Tesco Korea to actively get involved in retailer brand program. As a result, Tesco Korea has led retailer brand market in the Korean marketplace. The research starts with the question of why Tesco Korea has achieved such a higher retailer brand share. Accordingly, this study is to explore how Tesco UK has transferred its own retailing knowledge into Tesco Korea, in terms of retailer brand program development. In order to explore why the retailer brand share of Tesco Korea is higher than that of its counterparts, the author adopted in-depth interview with prepared-questions and store observation as a research methodology. To examine working process as well as information flows within Tesco Korea and from UK to Korea, in-depth interview method is one of the most suitable research methodologies, because of the difficulty of quantifying information or data related to work flows. In addition, to increase the validity of information, the researcher had interviews with Tesco Korea supplier and store personnel. Based on these research techniques, this research explored how Tesco UK has influenced or advised Tesco Korea, particularly, from the point of view of knowledge transfer. Since the entry of Tesco UK into Korea as a joint-venture, the retailer brand market share of Tesco Korea has continuously increased. It would be expected that Tesco UK has helped Tesco Korea to settle down in the Korean market. During interviews with Tesco and a Tesco supplier, the researcher found that Tesco Korea has obviously taken an advantage of retailing know-how created by Tesco UK. Furthermore, the retailer brand development and handling process of Tesco Korea has been operated with the help of Tesco UK. This might mean that Tesco UK has directly or indirectly an impact on the improvement of Korean retailer brand development skills. As a mechanism to transfer retailing knowledge developed in the home market into the host market, one of the international retailers, Tesco UK has adopted many different ways such as annual meeting, trading meeting to import or export own retailer brand products, offering of operation manual developed by Tesco UK and buyer cooperation between Tesco UK and Korea, in order to share information. Through these communication techniques, the knowledge of Tesco UK has been transferred to Tesco Korea. This research accordingly suggests that retailer brand market share is apparently related to how sophisticated or advanced the knowledge of the retailer brand development and handling process of retailers are. It is also demonstrated by this research that advanced development and handling skills make a considerable contribution to increasing retailer brand share in markets with a lower share or no presence of retailer brands.

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