• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1990년도 추계학술대회
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• pp.52-53
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• 1990

• Journal of Chest Surgery
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• 제28권6호
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• pp.630-632
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• 1995

Bichamber cardiac rupture is less frequent compared to unichamber cardiac rupture. We report a patient who was successfully treated after the diagnosis of penetrating stab wound of both ventricles. The key to improved outcome of management of cardiac trauma lies in the rapid transportation to a general hospital where cardiac surgery is available. Aggressive primary intervention and immediate operation are also major factors.

• Journal of Chest Surgery
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• 제48권3호
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• pp.228-230
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• 2015

We report a rare case of an extremely large right ventricular myxoma involving the ventricular side of the tricuspid valve. The tumor was excised along with the entire posterior leaflet and part of the anterior leaflet. The tricuspid valve was repaired by sliding valvuloplasty combined with ring annuloplasty.

• 한국임상수의학회:학술대회논문집
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• 한국임상수의학회 2007년도 추계국제학술대회 및 컨퍼런스
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• pp.556-556
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• 2007

• 한국생물물리학회:학술대회논문집
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• 한국생물물리학회 1999년도 학술발표회 진행표 및 논문초록
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• pp.59-59
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• 1999

Circulating substances can directly access the neurons in circumventricular organ (CVO) located on the border of cerebral ventricles. The neurons in CVO are considered to playa pivotal role in blood-brain communication. In subfonical organ (SFO), a CVO in forebrain, angiotensin II (AII) is mown to reduce A type $K^{＋}$ current and input resistance, but enhance firing rate.(omitted)

• Korean Journal of Radiology
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• 제2권2호
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• pp.105-107
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• 2001

Meningiomas causing intracranial hemorrhage are rare, and hemorrhage from a lateral ventricular meningioma seems to be even rarer. We report a case of trigonal meningioma in a 43-year-old woman who presented with intraventricular hemorrhage, and describe the CT, MRI and angiographic findings.

• Journal of Yeungnam Medical Science
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• 제37권4호
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• pp.345-348
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• 2020

Papillary fibroelastomas are the second most common primary cardiac tumor in adults. Over 80% of fibroelastomas occur on the cardiac valves, usually on the left side of the heart, while the remaining lesions are typically scattered throughout the atria and ventricles. Although the optimal timing for surgery is controversial and depends on tumor size and location, prompt surgical resection is warranted in patients at high risk of embolism. A tumor on the cardiac valve can be removed using the slicing excision technique without leaflet injury. Here we present two cases of papillary fibroelastomas occurring on the ventricular surface of the aortic valve and in the right ventricle.

• 대한의용생체공학회:의공학회지
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• 제22권5호
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• pp.413-418
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• 2001

수두증 환자의 뇌압을 조절하기 위해 사용되는 션트밸브의 개발을 수행하였다. 개발을 목표로 하는 밸브는 실리콘 일래스토머를 주재료로 하는 일정압력형 VP (ventriculoperitoneal) 밸브이다 시제작된 밸브는 In Vitro 실험을 통해 기존의 상용 밸브와 유사한 압력-유량 조절특성을 나타냈으며 IS07197 기준에 따른 28일간의 내구성 테스트에서 뒤지지 않는 결과를 보였다. 제작된 밸브의 치료효과를 실험하기 위해 10kg 개 (beagle dog)에게 인위적으로 수두증을 유발시킨 결과. 뇌실이 크게 팽창하고 행동에 이상을 보였으나 션트밸브를 시술한 결과 수두증에 의해 팽창된 뇌실이 현저하게 줄어들고 정상 크기를 회복하였으며 행동이 정상적으로 돌아왔다 션트밸브의 유동 오리피스의 크기가 동작 중에 10 마이크로미터 이내이며 약간의 오타에 의해서도 압력조절특성이 변화하므로 밸브의 성공적인 동작을 위해서는 정밀한 설계와 제조기술이 요구되었다.

• Journal of Korean Neurosurgical Society
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• 제49권6호
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• pp.334-338
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• 2011

Objective : The incidence of leptomeningeal dissemination from malignant glioma is rare, so the clinical features of this are not well documented yet We attempted to determine the clinical features of leptomeningeal dissemination from malignant gliomas. Methods : We retrospectively analyzed 11 cases of leptomeningeal dissemination of malignant glioma, who were treated at our institution between 2006 and 2009. We investigated the clinical features of these patients by considering the following factors : tumor locations, the events of ventricular opening during surgery and the cerebrospinal fluid (CSF) profiles, including the cytology. Results : The group was composed of 9 males and 2 females. The histological diagnosis of their initial intracranial tumors were 4 primary glioblastoma, 3 anaplastic astrocytoma, 1 anaplastic oligoastrocytoma, 2 ganglioglioma and 1 pleomorphic xanthoastrocyotma with anaplastic features. The mean age of the patients at the time of the initial presentation was $42.8{\pm}10.3$ years. The mean time between surgery and the diagnosis of spinal dissemination was $12.3{\pm}7.9$ (3-28) months. The mean overall survival after dissemination was $2.7{\pm}1.3$ months. All our patients revealed a history of surgical opening of the ventricles. Elevated protein in the CSF was reported for eight patients who had their CSF profiles checked. Conclusion : We propose that in the malignant gliomas, the surgical opening of ventricles can cause the spinal leptomeningeal dissemination and the elevated protein content of CSF may be a candidate marker of leptomeningeal dissemination.

• Biomolecules & Therapeutics
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• 제21권1호
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• pp.84-88
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• 2013

High risk of cardiovascular diseases caused by existing PPAR-${\gamma}$ agonists such as rosiglitazone and pioglitazone has been recently reported. CKD-501 is a novel selective PPAR-${\gamma}$ agonist as a potential target to reduce cardiovascular risk in non-insulin dependent diabetes mellitus (NIDDM). In this study, We investigated potential cardiotoxicity of CKD-501 and compared its toxicity with that of rosiglitazone or pioglitazone using db/db mice. After 12-week repeated administration of CKD-501 at doses of 3, 10 and 30 mg/kg/day or rosiglitazone at doses of 10 and 30 mg/kg/day or pioglitazone at doses of 200 and 540 mg/kg/day, animals were sacrificed for investigation of potential toxicities. Diameters of left ventricles and areas of cardiomyocytes were measured. And lipid accumulation and apoptosis in heart muscle were examined by oil red O staining and TUNEL staining, respectively. Diameters of left ventricles were significantly increased in high dose treatment group of pioglitazone compared to control (p<0.05), while other groups showed a tendency for an increase. All test articles induced significantly the increase of area of cardiomyocytes in heart compared to control (p<0.01), in regular order as pioglitazone > CKD-501 ${\geq}$ rosiglitazone. However, lipid accumulation and apoptotic changes in heart were not observed in all dosing groups. Taken together, the myocardial cell hypertrophy of CKD-501 are relatively lower than that of pioglitazone and similar to rosiglitazone. And it is suggested that the myocardial cell hypertrophy of CKD-501 are less adverse in clinical use for the management of the NIDDM.