• Title/Summary/Keyword: Vehicle domain

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Enhanced Transduction of Cu,Zn-Superoxide Dismutase with HIV-1 Tat Protein Transduction Domains at Both Termini

  • Eum, Won Sik;Jang, Sang Ho;Kim, Dae Won;Choi, Hee Soon;Choi, Soo Hyun;Kim, So Young;An, Jae Jin;Lee, Sun Hwa;Han, Kyuhyung;Kang, Jung Hoon;Kang, Tae-Cheon;Won, Moo Ho;Cho, Yong Joon;Choi, Jin Hi;Kim, Tae Yoon;Park, Jinseu;Choi, Soo Young
    • Molecules and Cells
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    • v.19 no.2
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    • pp.191-197
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    • 2005
  • The human immunodeficiency virus type 1 (HIV-1) Tat protein transduction domain (PTD) is responsible for highly efficient protein transduction across plasma membranes. In a previous study, we showed that Tat-Cu,Zn-superoxide dismutase (Tat-SOD) can be directly transduced into mammalian cells across the lipid membrane barrier. In this study, we fused the human SOD gene with a Tat PTD transduction vector at its N- and/or C-terminus. The fusion proteins (Tat-SOD, SOD-Tat, Tat-SOD-Tat) were purified from Escherichia coli and their ability to enter cells in vitro and in vivo compared by Western blotting and immunohistochemistry. The transduction efficiencies and biological activities of the SOD fusion protein with the Tat PTD at either terminus were equivalent and lower than the fusion protein with the Tat PTD at both termini. The availability of a more efficient SOD fusion protein provides a powerful vehicle for therapy in human diseases related to this anti-oxidant enzyme and to reactive oxygen species.

The Study of Driving Fatigue using HRV Analysis (HRV 분석을 이용한 운전피로도에 관한 연구)

  • 성홍모;차동익;김선웅;박세진;김철중;윤영로
    • Journal of Biomedical Engineering Research
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    • v.24 no.1
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    • pp.1-8
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    • 2003
  • The job of long distance driving is likely to be fatiguing and requires long period alertness and attention, which make considerable demands of the driver. Driving fatigue contributes to driver related with accidents and fatalities. In this study, we investigated the relationship between the number of hours of driving and driving fatigue using heart rate variability(HRV) signal. With a more traditional measure of overall variability (standard deviation, mean, spectral values of heart rate). Nonlinear characteristics of HRV signal were analyzed using Approximate Entropy (ApEn) and Poincare plot. Five subjects drive the four passenger vehicle twice. All experiment number was 40. The test route was about 300Km continuous long highway circuit and driving time was about 3 hours. During the driving, measures of electrocardiogram(ECG) were performed at intervals of 30min. HRV signal, derived from the ECG, was analyzed using time, frequency domain parameters and nonlinear characteristic. The significance of differences on the response to driving fatigue was determined by Student's t-test. Differences were considered significant when a p value < 0.05 was observed. In the results, mean heart rate(HRmean) decreased consistently with driving time, standard deviation of RR intervals(SDRR), standard deviation of the successive difference of the RR intervals(SDSD) increased until 90min. Hereafter, they were almost unchanging until the end of the test. Normalized low frequency component $(LF_{norm})$, ratio of low to high frequency component (LF/HF) increased. We used the Approximate Entropy(ApEn), Poincare plot method to describe the nonlinear characteristics of HRV signal. Nonlinear characteristics of HRV signals decreased with driving time. Statistical significant is appeared after 60 min in all parameters.

A Study on the Iconization of Che Guevara Expressed in Contemporary Fashion (현대 패션에 나타난 체 게바라(Che Guevara)의 아이콘화에 관한 연구)

  • Kim, Hye-Jeong
    • Journal of the Korean Society of Costume
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    • v.56 no.3 s.102
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    • pp.1-11
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    • 2006
  • Che Guevara spearheading the Cuban Revolution was not only the icon as the revolutionary to the New-leftists of the 1960s advocating the ideology of Marxism but, as the cultural revolutionary, had a tremendous influence on the younger generation living in the digital age Che Guevara take on a figure of both the symbol of the Leftist but the romantic revolutionary because he had the external features such as black beret, red stars, military upper jackets and trousers, beard and pipe tobacco. In fact, the symbolic image of Che Guevara was made as the popular image by the avantgarde artists and political vanguard forces of the times under the necessity of Cuban government. Afterwards, the image of Che Guevara has been patronized in making people of aware of the resistant and revolutionary image to capital, power and the power of the media and symbolized as the resistant image to the American capital as well as the revolutionary guerrilla. And his image has continued to be reproduced and symbolized for the commercial and political purposes and as the enthusiastic image of youth culture. This can be seen as having been created as a new image by the popular culture formed by the development of the cyber culture and mass media in the cyberspace shaped by contemporary 'N' generations. The use of Che Guevara's symbolic image was made in the fashion field as well as in the cultural and artistic circles. The borrowing of the icon of Che Guevara represented in a fashion field is attributed to his free spirit, and it can be seen that fashion exists as the vehicle for representing both the symbol system and the sign system containing ideologies and texts as the communicator of resistance to the regime and to social issues. Therefore, this study attempted to investigate the commercial iconization of Che Guevara in the 1990s by comparing the ideology of the symbol in the 1960s and the 1990s and inquire into the borrowing of his image by the fashion domain as well as the fashion worn by him by reference to domestic books and materials on the fashion site. Thereby, this study attempted to make clear that the borrowing of Che Guevara in the realm of fashion since the 1990s not only contained the meaningful interpretation as the symbolic code in the culture of young people living in a digital era but fashion performs an intervening role in the cultural phenomenon.

Numerical Study on the Performance Assessment for Defrost and De-Icing Modes (승용차의 제상 및 성에 제거 성능 평가를 위한 수치해석적 연구)

  • Kim, Yoon-Kee;Yang, Jang-Sik;Kim, Kyung-Chun;Ji, Ho-Seong
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.35 no.2
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    • pp.161-168
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    • 2011
  • The heating, ventilating, air conditioning (HVAC) system is a very important part of an automotive vehicle: it controls the microclimate inside the passenger's compartment and removes the frost or mist that is produced in cold/rainy weather. In this study, the numerical analysis of the defrost duct in an HVAC system and the de-icing pattern is carried out using commercial CFX-code. The mass flow distribution and flow structure at the outlet of the defrost duct satisfied the duct design specification. For analyzing the de-icing pattern, additional grid generation of solid domain of ice and glass is pre-defined for conductive heat transfer. The flow structure near the windshield, streakline, and temperature fields clearly indicate that the de-icing capacity of the given defrost duct configuration is excellent and that it can be operated in a stable manner. In this paper, the unsteady changes in temperature, water volume fraction, and static enthalpy at four monitoring points are discussed.

A Study of Traffic Noise Characteristics on the National Highways (일반국도의 교통소음특성에 관한 연구)

  • Son, Hyeon Jang;An, Deok-Soon;Baek, Cheolmin;Kwon, Soo-Ahn;Lee, Jaejun
    • International Journal of Highway Engineering
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    • v.15 no.2
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    • pp.11-18
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    • 2013
  • PURPOSES : This study presents the noise level and frequency characteristics investigated in the national highways with the consideration of various measuring conditions and/or methods. METHODS : The noise levels on the asphalt concrete pavement(ACP) and the jointed plain concrete pavement(JPCP) of the national highway were measured and analysed with respect to three variables, i.e., pavement type, surface condition, and measurement distance. The PASS-By method is utilized for the noise measurement and then using CPB spectrum analysis method with 1/3 octave bandwidth, the noise levels and frequency characteristics were calculated for two-second periods before and after the peak noise. RESULTS : Depending on the pavement type, the noise level was changed as the average noise levels are 73.3dB(A) and 78.3dB(A) for ACP and JPCP, respectively. With respect to the effect of surface condition, the average noise levels for crack H(high), M(medium), and L (low) sections are 77.4dB(A), 77.4dB(A), and 78.1dB(A), respectively. Regarding the measurement distance, 1.2meter difference in measuring location reduces 1.6dB(A) of noise level; the average noise levels at 5.3m and 7.5m from the centerline of outer lane are 72.8dB(A) and 71.2dB(A), respectively. It should be noted that the noise levels are slightly different as a function of vehicle speed and type. However, the overall trends for each case was similar. It was found that the domain frequency bands for ACP and JPCP were 400Hz~2000Hz and 500Hz~2000Hz, respectively. CONCLUSIONS : Based on the analysis with the measured noise date from national highway, it was concluded that the noise level and frequency band vary depending on the various conditions. It was also found that some variables significantly affect the noise level while others do not. With further systematic investigation, the comprehensive noise characteristics on the national highway can be achieved. Using such database, it is possible to develop the fundamental noise reduction technology.

Calculation of Deflection Using the Acceleration Data for Concrete Bridges (가속도 계측 자료를 이용한 콘크리트 교량의 처짐 산정)

  • Yun, Young Koun;Ryu, Hee Joong
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.15 no.5
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    • pp.92-100
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    • 2011
  • This paper describes a numerical modeling for deflection calculation using the natural frequency response that is measured acceleration response for concrete bridges. In the formulation of the dynamic deflection, the change amounts and the transformed responses about six kinds of free vibration responses are defined totally. The predicted response can be obtained from the measured acceleration data without requiring the knowledge of the initial velocity and displacement information. The relationship between the predicted response and the actual deflection is derived using the mathematical modeling that is induced by the process of a acceleration test data. In this study, in order to apply the proposed response predicted model to the integration scheme of the natural frequency domain, the Fourier Fast Transform of the deflection response is separated into the frequency component of the measured data. The feasibility for field application of the proposed calculation method is tested by the mode superposition method using the PSC-I bridges superstructures under several cases of moving load and results are compared with the actually measured deflections using transducers. It has been observed that the proposed method can asses the deflection responses successfully when the measured acceleration signals include the vehicle loading state and the free vibration behavior.

Development of Autonomous Vehicle Learning Data Generation System (자율주행 차량의 학습 데이터 자동 생성 시스템 개발)

  • Yoon, Seungje;Jung, Jiwon;Hong, June;Lim, Kyungil;Kim, Jaehwan;Kim, Hyungjoo
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.19 no.5
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    • pp.162-177
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    • 2020
  • The perception of traffic environment based on various sensors in autonomous driving system has a direct relationship with driving safety. Recently, as the perception model based on deep neural network is used due to the development of machine learning/in-depth neural network technology, a the perception model training and high quality of a training dataset are required. However, there are several realistic difficulties to collect data on all situations that may occur in self-driving. The performance of the perception model may be deteriorated due to the difference between the overseas and domestic traffic environments, and data on bad weather where the sensors can not operate normally can not guarantee the qualitative part. Therefore, it is necessary to build a virtual road environment in the simulator rather than the actual road to collect the traning data. In this paper, a training dataset collection process is suggested by diversifying the weather, illumination, sensor position, type and counts of vehicles in the simulator environment that simulates the domestic road situation according to the domestic situation. In order to achieve better performance, the authors changed the domain of image to be closer to due diligence and diversified. And the performance evaluation was conducted on the test data collected in the actual road environment, and the performance was similar to that of the model learned only by the actual environmental data.

Spatial Factors' Analysis of Affecting on Automated Driving Safety Using Spatial Information Analysis Based on Level 4 ODD Elements (Level 4 자율주행서비스 ODD 구성요소 기반 공간정보분석을 통한 자율주행의 안전성에 영향을 미치는 공간적 요인 분석)

  • Tagyoung Kim;Jooyoung Maeng;Kyeong-Pyo Kang;SangHoon Bae
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.22 no.5
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    • pp.182-199
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    • 2023
  • Since 2021, government departments have been promoting Automated Driving Technology Development and Innovation Project as national research and development(R&D) project. The automated vehicles and service technologies developed as part of these projects are planned to be subsequently provided to the public at the selected Living Lab City. Therefore, it is important to determine a spatial area and operation section that enables safe and stable automated driving, depending on the purpose and characteristics of the target service. In this study, the static Operational Design Domain(ODD) elements for Level 4 automated driving services were reclassified by reviewing previously published papers and related literature surveys and investigating field data. Spatial analysis techniques were used to consider the reclassified ODD elements for level 4 in the real area of level 3 automated driving services because it is important to reflect the spatial factors affecting safety related to real automated driving technologies and services. Consequently, a total of six driving mode changes(disengagement) were derived through spatial information analysis techniques, and the factors affecting the safety of automated driving were crosswalk, traffic light, intersection, bicycle road, pocket lane, caution sign, and median strip. This spatial factor analysis method is expected to be useful for determining special areas for the automated driving service.

Comparison of Association Rule Learning and Subgroup Discovery for Mining Traffic Accident Data (교통사고 데이터의 마이닝을 위한 연관규칙 학습기법과 서브그룹 발견기법의 비교)

  • Kim, Jeongmin;Ryu, Kwang Ryel
    • Journal of Intelligence and Information Systems
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    • v.21 no.4
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    • pp.1-16
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    • 2015
  • Traffic accident is one of the major cause of death worldwide for the last several decades. According to the statistics of world health organization, approximately 1.24 million deaths occurred on the world's roads in 2010. In order to reduce future traffic accident, multipronged approaches have been adopted including traffic regulations, injury-reducing technologies, driving training program and so on. Records on traffic accidents are generated and maintained for this purpose. To make these records meaningful and effective, it is necessary to analyze relationship between traffic accident and related factors including vehicle design, road design, weather, driver behavior etc. Insight derived from these analysis can be used for accident prevention approaches. Traffic accident data mining is an activity to find useful knowledges about such relationship that is not well-known and user may interested in it. Many studies about mining accident data have been reported over the past two decades. Most of studies mainly focused on predict risk of accident using accident related factors. Supervised learning methods like decision tree, logistic regression, k-nearest neighbor, neural network are used for these prediction. However, derived prediction model from these algorithms are too complex to understand for human itself because the main purpose of these algorithms are prediction, not explanation of the data. Some of studies use unsupervised clustering algorithm to dividing the data into several groups, but derived group itself is still not easy to understand for human, so it is necessary to do some additional analytic works. Rule based learning methods are adequate when we want to derive comprehensive form of knowledge about the target domain. It derives a set of if-then rules that represent relationship between the target feature with other features. Rules are fairly easy for human to understand its meaning therefore it can help provide insight and comprehensible results for human. Association rule learning methods and subgroup discovery methods are representing rule based learning methods for descriptive task. These two algorithms have been used in a wide range of area from transaction analysis, accident data analysis, detection of statistically significant patient risk groups, discovering key person in social communities and so on. We use both the association rule learning method and the subgroup discovery method to discover useful patterns from a traffic accident dataset consisting of many features including profile of driver, location of accident, types of accident, information of vehicle, violation of regulation and so on. The association rule learning method, which is one of the unsupervised learning methods, searches for frequent item sets from the data and translates them into rules. In contrast, the subgroup discovery method is a kind of supervised learning method that discovers rules of user specified concepts satisfying certain degree of generality and unusualness. Depending on what aspect of the data we are focusing our attention to, we may combine different multiple relevant features of interest to make a synthetic target feature, and give it to the rule learning algorithms. After a set of rules is derived, some postprocessing steps are taken to make the ruleset more compact and easier to understand by removing some uninteresting or redundant rules. We conducted a set of experiments of mining our traffic accident data in both unsupervised mode and supervised mode for comparison of these rule based learning algorithms. Experiments with the traffic accident data reveals that the association rule learning, in its pure unsupervised mode, can discover some hidden relationship among the features. Under supervised learning setting with combinatorial target feature, however, the subgroup discovery method finds good rules much more easily than the association rule learning method that requires a lot of efforts to tune the parameters.

Analysis of Micro-Sedimentary Structure Characteristics Using Ultra-High Resolution UAV Imagery: Hwangdo Tidal Flat, South Korea (초고해상도 무인항공기 영상을 이용한 한국 황도 갯벌의 미세 퇴적 구조 특성 분석)

  • Minju Kim;Won-Kyung Baek;Hoi Soo Jung;Joo-Hyung Ryu
    • Korean Journal of Remote Sensing
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    • v.40 no.3
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    • pp.295-305
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    • 2024
  • This study aims to analyze the micro-sedimentary structures of the Hwangdo tidal flats using ultra-high resolution unmanned aerial vehicle (UAV) data. Tidal flats, located in the transitional area between land and sea, constantly change due to tidal activities and provide a unique environment important for understanding sedimentary processes and environmental conditions. Traditional field observation methods are limited in spatial and temporal coverage, and existing satellite imagery does not provide sufficient resolution to study micro-sedimentary structures. To overcome these limitations, high-resolution images of the Hwangdo tidal flats in Chungcheongnam-do were acquired using UAVs. This area has experienced significant changes in its sedimentary environment due to coastal development projects such as sea wall construction. From May 17 to 18, 2022, sediment samples were collected from 91 points during field surveys and 25 in-situ points were intensively analyzed. UAV data with a spatial resolution of approximately 0.9 mm allowed identifying and extracting parameters related to micro-sedimentary structures. For mud cracks, the length of the major axis of the polygons was extracted, and the wavelength and ripple symmetry index were extracted for ripple marks. The results of the study showed that in areas with mud content above 80%, mud cracks formed at an average major axis length of 37.3 cm. In regions with sand content above 60%, ripples with an average wavelength of 8 cm and a ripple symmetry index of 2.0 were formed. This study demonstrated that micro-sedimentary structures of tidal flats can be effectively analyzed using ultra-high resolution UAV data without field surveys. This highlights the potential of UAV technology as an important tool in environmental monitoring and coastal management and shows its usefulness in the study of sedimentary structures. In addition, the results of this study are expected to serve as baseline data for more accurate sedimentary facies classification.