• Journal of Korean Academy of Nursing
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• v.39 no.5
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• pp.632-640
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• 2009

Purpose: The purpose of this study was to examine the effect of DHEA (Dehydroepiandrosterone) on muscle weight and Type I and II fiber cross-sectional area of affected and unaffected hindlimb muscles in rats with neuropathic pain induced by unilateral peripheral nerve injury. Methods: Neuropathic pain was induced by ligation and cutting of the left L5 spinal nerve. Adult male Sprague-Dawley rats were randomly assigned to one of two groups: The DHEA group (n=10) had DHEA injections daily for 14 days, and the Vehicle group (n=10) had vehicle injections daily for 14 days. Withdrawal threshold, body weight, food intake and activity were measured every day. At 15 days all rats were anesthetized and soleus, plantaris and gastrocnemius muscles were dissected from the both hindlimbs. Body weight, food intake, activity, muscle weight and Type I, II fiber cross-sectional area of the dissected muscles were measured. Results: The DHEA group showed significant increases (p<.05), as compared to the vehicle group for muscle weight of the unaffected plantaris, and in Type II fiber cross-sectional area of the gastrocnemius muscle. The DHEA group demonstrated a higher pain threshold than the vehicle group whereas total diet intake and activity score were not significantly different between the two groups. Conclusion: DHEA administration for 14 days attenuates unaffected plantaris and gastrocnemius muscle atrophy.

• Journal of Oriental Neuropsychiatry
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• v.22 no.2
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• pp.129-146
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• 2011

Objectives : The purpose of this study was to characterize the putative antidepressant and antianxiolytic effects of the 70% ethanol extract of Polygala japonica(EEPJ) using animal's behavioral experiment in mice. Methods : The effect of EEPJ on the anxioty and depressive disorder was investigated via mice's behavioral experiment like Elevated plus-maze, Horizontal wire test, Open field test, Forced swimming test, Tail suspension test, and it was happen via any mechanism by WAY 100635, a 5-HT1A receptor antagonist and by Flumazenil, a GABAA antagonist Results : 1. In the EPM, single treatments of the EEPJ(200 and 400mg/kg) had usefully antianxiolytic effects versus vehicle, which was medicated via the serotonergic nervous system. 2. In the HWT, single treatments of the EEPJ were no changes in the myorelaxant effects versus vehicle. 3. In the OFT, single treatments of the EEPJ were no changes in the locomotor activity versus vehicle. 4. In the FST, single treatments of the EEPJ(50mg/kg) significantly reduced the immobility time versus vehicle. 5. In the TST, single treatments of the EEPJ(50mg/kg) significantly reduced the immobility time versus vehicle. Conclusions : These results indicate that EEPJ is an effective antidepressant and antianxiolytic activity in mice, and it might be usefully applied for prevention and treatment of depressive disorder through evolutive study like development of various experimental models.

• Journal of Korean Institute of Industrial Engineers
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• v.14 no.1
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• pp.119-131
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• 1988

Vehicle Scheduling Problem (VSP) is a generic name given to a whole class of problems involving the visiting of "stations" by "vehicles," where a time is associated with each activity. The studies performed to date have the common feature of a single objective while satisfying a set of restrictions and known customer supplies or demands. However, VSPs may involve relevant multiple objectives and probabilistic supplies or demands at stations, creating multicriteria stochastic VSPs. This paper proposes a heuristic algorithm based on goal programming approach to schedule the most satisfactory vehicle routes of a bicriteria VSP with probabilistic supplies at stations. The two relevant objectives are the minimization of the expected travel distance of vehicles and the minimization of the due time violation for collection service at stations by vehicles. The algorithm developed consists of three major stages. In the first stage, an artificial capacity of vehicle is determined, on the basis of decision maker's subjective estimates. The second one clusters a set of stations into subsets by applying an efficient cluster method developed. In the third one, the stations in each subset are scheduled by applying an iterative goal programming heuristic procedure to each cluster.

• The Bulletin of The Korean Astronomical Society
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• v.37 no.2
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• pp.195.1-195.1
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• 2012

Korea Aerospace Research Institute has developed an earth observation satellite whose primary mission objective is to provide high resolution electro optical earth images for Geographical Information Systems (GIS) establishment and the applications for environmental, agriculture and ocean monitoring. It was successfully launched into its mission orbit by using a commercial launch vehicle on 18th of May, 2012. This paper describes a series of launch activity at the launch site including its transportation to the launch site. Before conducting the launch site operation, satellite operation plane was prepared. Combining the satellite operation plan and launch vehicle activities, an integrated launch site operation plan and schedule have been drawn up. After arrival of the spacecraft at the launch site, post-ship check out has been conducted. And then it was fuel loaded and integrated with launch vehicle hardware. After completion of final electrical check out, count down procedure was executed. on 18th of May, it was launched into the space and was separated from the launch vehicle as planned. About 3 months of early operation and calibration/validation, now the satellite is conducting its normal mission.

• Science of Emotion and Sensibility
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• v.25 no.1
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• pp.3-20
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• 2022

Recently, prior to the commercialization of urban air mobility (UAM), the importance of R&D for air transportation-related industries in urban areas has significantly increased. To create a UAM environment, research is being conducted on personal air vehicles (PAVs). They are key means of air transportation, but research on the physical factors influencing their passengers is relatively insufficient. In particular, because the PAV is expected to be used as a living space for the passengers, research on the effects of the physical elements generated in the PAV on the human body is essential to design an interior space that supports the in-vehicle activities of the passengers. Therefore, the purpose of this study is to derive the constraint factors that affect the human body due to the air navigation characteristics of the PAV and to understand the impact of these constraint factors on the bodies of the passengers performing in-vehicle activities. The results of this study indicate that when the PAV was operated at less than 4,000 ft, which is the operating standard, the constraint factors were noise, vibration, and motion sickness caused by low-frequency motion. These constraint factors affect in-vehicle activity; thus, the in-vehicle activities that can be performed in a PAV were derived using autonomous cars, airplanes, and PAV concept cases. Furthermore, considering the impact of the constraint factors and their levels on the human body, recommended constraint factor criteria to support in-vehicle activities were established. To reduce the level of impact of the constraint factors on the human body and to support in-vehicle activity, the seat's shape and built-in functions of the seat (vibration reduction function, temperature control, LED lighting, etc.) and external noise reduction using a directional speaker for each individual seat were recommended. Moreover, it was suggested that interior materials for noise and vibration reduction should be used in the design of the interior space. The contributions of this study are the determination of the constraint factors affecting the in-vehicle PAV activity and the confirmation of the level of impact of the factors on the human body; in the future, these findings can be used as basic data for suitable PAV interior design.

• Proceedings of the IEEK Conference
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• 2004.08c
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• pp.729-734
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• 2004

The e-Logistics means the virtual business activity and service architecture among the logistics companies based on the Internet technology. The management of vehicles' location in most conventional vehicle tracking system has some critical defects when it deals with data which are continuously changed. It means the conventional vehicle tracking system based on the conventional database is unable eventually to cope with the environment that should manage the frequently changed location of vehicles. The important things in the evaluation of the vehicle tracking system is to determine the threshold of cost of database ,update period and communication period between vehicles and the system. In other words, the difference between the reallocation of vehicle and the data in database can evaluate the overall performance of vehicle tracking systems. Most of the previous works considers only the information that is valid at the current time, and is hard to manage efficiently the past and future information. To overcome this problem, the efforts on moving objects management system(MOMS) and uncertainty processing have been started from a few years ago. In this paper, we propose an uncertainty processing model and system implementation of moving object that tracks the location of the vehicles. We adopted both linear-interpolation method and trigonometric function to chase up the location of vehicles for the past time as well as future time, respectively. We also explain the comprehensive examples of MOMS and uncertainty processing in parcel application that is one of major application of e-Logistics domain.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.10 no.11
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• pp.5322-5342
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• 2016

In vehicle-to-vehicle (V2V) networks, where selfishness degrades node activity, countermeasures for collaboration enforcement must be provided to enable application of a sage and efficient network environment. Because vehicular networks feature both high mobility and various topologies, selfish behavior judgment and establishment of a stable routing protocol become intensely challenging. In this paper, a two-phase-based generous cooperative routing protocol (called GEC) is presented for V2V networks to provide resistance to selfishness. To detect selfish behaving vehicles, a packet forwarding watchdog and an average connection rate based on the multipath weight method are used, where evidence is gathered from different watchdogs. Then, multihop relay decisions are made using a generous cooperative algorithm based on game theory. Finally, through buffering of the multiple end-to-end paths and judicious choice of optimal cooperative routes, route maintenance phase is capable of dealing with congestion and rapidly exchanging traffic. Specifically, it is proved that the GEC is theoretically subgame perfect. Simulation results show that for V2V networks with inherently selfish nodes, the proposed method isolates uncooperative vehicles and is capable of accommodating both the mobility and congestion circumstances by facilitating information dissemination and reducing end-to-end delay.

• YAKHAK HOEJI
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• v.35 no.4
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• pp.295-300
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• 1991

Ralationship between noradrenergic nervous system activity and luteinizing hormone releasing hormone(LHRH) content mediated by testosterone in hypothalamus was tested. Three groups of adult male animals were prepared; (1) Intact; (2) Castration+Vehicle (Cast+V); (3) Castration+Testosterone (Cast+T). Silastic capsule containing vehicle or testosterone was implanted into neck region of animals two weeks following castration. Norepinephrine content, alpha-adrenergic receptor binding characteristics using H$^{3}$-WB4101, and content of LHRH by LHRH RIA procedure were determined. Testosterone replacement to castrated male rats augmented the content of norepinephrine and LHRH. Testosterone replacement increased the alpha-adrenergic receptor density but did not change alpha-receptor affinity. The data from the present study suggest that increase in LHRH content by testosterone may be positively coupled to the activity of central noradrenergic nervous system.

• Transactions of the Korean Society of Automotive Engineers
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• v.11 no.2
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• pp.134-139
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• 2003

This study was carried out to investigate the aging and conversion characteristics of oxidation catalysts for a natural gas vehicle with lean-bum system. The conversion of $CH_4$ was observed over the various composition ratio of PMs(Precious metals) and washcoating methods. On the fresh catalysts, Pd affected on the activity of $CH_4$ at low temperature more than other PMs in Pd-only and Rh/Pd/Pt catalysts. The activity at low temperature increased as a mount of Pd increases. On the aged catalysts, the $CH_4$ conversion efficiency of Pd-only catalyst with mono-layer washcoat decreased more than that of the other catalysts of $CH_4$ conversion. It was observed that the thermal durability of Rh/Pd/Pt catalysts with double-layer washcoat was better than the single washcoat catalyst.

• The Journal of the Korea Contents Association
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• v.21 no.3
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• pp.68-79
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• 2021

On the Social Internet of Things (SIoT), social activities occur through which the vehicle generates a variety of data, shares them with other vehicles, and sends and receives feedbacks. In order to share reliable information between vehicles, it is important to determine the reliability of a vehicle. In this paper, we propose a vehicle trust evaluation scheme to share reliable information among vehicles. The proposed scheme calculates vehicle trust by considering user reputation and network trust based on inter-vehicle social behaviors. The vehicle may choose to scoring, ignoring, redistributing, etc. in the social activities inter vehicles. Thereby, calculating the user's reputation. To calculate network trust, distance from other vehicles and packet transmission rate are used. Using user reputation and network trust, local trust is calculated. It also prevents redundant distribution of data delivered during social activities. Data from the Road Side Unit (RSU) can be used to overcome local data limitations and global data can be used to calculate a vehicle trust more accurately. It is shown through various performance evaluations that the proposed scheme outperforms the existing schemes.