• Archives of Plastic Surgery
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• 제44권4호
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• pp.340-343
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• 2017

Performing rhinoplasty using filler injections, which improve facial wrinkles or soft tissues, is relatively inexpensive. However, intravascular filler injections can cause severe complications, such as skin necrosis and visual loss. We describe a case of blepharoptosis and skin necrosis caused by augmentation rhinoplasty and we discuss the patient's clinical progress. We describe the case of a 25-year-old female patient who experienced severe pain, blepharoptosis, and decreased visual acuity immediately after receiving a filler injection. Our case suggests that surgeons should be aware of nasal vascularity before performing an operation, and that they should avoid injecting fillers at a high pressure and/or in excessive amounts. Additionally, filler injections should be stopped if the patient complains of severe pain, and appropriate measures should be taken to prevent complications caused by intravascular filler injections.

• Imaging Science in Dentistry
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• 제31권1호
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• pp.57-65
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• 2001

Osteoradionecrosis is one of the most serious complication after heavy irradiation of bone and most particularly following treatment of cancers within the head and neck. The irradiated bone has the decreased vascularity and is easily infected. As a result, the spread of infection may cause a nonhealing wound that is very difficult to be treated. A comprehensive prophylactic dental care as well as proper blocking of the radiation field before radiotherapy must be considered to reduce the risk of osteoradionecrosis. We present three cases of osteoradionecrosis which developed after extraction of teeth in irradiated patients.

• Tuberculosis and Respiratory Diseases
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• 제38권2호
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• pp.202-206
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• 1991

Hemangiopericytoma is a rare tumor originating from pericytes of the small vessels. The most common sites of origin are the thigh and the retroperitoneum. The lung is a very uncommon site despite its high vascularity. We report a case of primary malignant hemangiopericytoma in the lung which developed in a 38 year-old woman, with brief review of literatures.

• 대한족부족관절학회지
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• 제16권1호
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• pp.26-30
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• 2012

The subtalar joint is a complex joint that is functionally responsible for inversion and eversion of the hindfoot. Advances in optical technology and surgical instrumentation have allowed the arthorscocpic surgeon to investiagate the small joints including the subtalar joint. Indications for subtalar arthroscopy include pain, swelling, stiffness and locking. Therapeutic indications include treatment of chondromalacia, osteophytes, arthrofibrosis, synovitis, loose bodies, osteochondral lesions, excision of a painful os trigonum, arthrodesis, and FHL tendinopathy. Contraindications to subtalar arthroscopy include infection, advanced osteoarthritis with deformity, severe edema, poor vascularity and poor skin quality. Subtalar arthroscopy is a technically demanding and difficult procedure that should only be performed by experienced surgeons. With proper instrumentation and careful operative techniques, satisfactory results may be obtained with minimal morbidity.

• 대한핵의학회지
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• 제37권4호
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• pp.260-261
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• 2003

Tc-99m methoxyisobutylisonitrile (MIBI) and Tl-201/technetium subtraction scintigraphy have been used for localization of abnormal parathyroid gland. The uptake mechanism of tracers has been postulated to be increased cellular density and vascularity, or dependent on the presence of mitochondria-rich cells. However, the uptake of these tracers was not specific for abnormal parathyroid gland. The author report a case of thymic carcinoma that would have been mistaken for carcinoma of parathyroid because of Tc-99m MIBI and Tl-201 uptake.

• 한국임상수의학회지
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• 제3권2호
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• pp.335-345
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• 1986

A total of 499 stomachs consisted of 393 slaughter and 106 breeding pigs from industrial farm was examined for ulcerative lesions grossly and microscopically. The relationship between the ulcerative lesions and stomach contents was also examined. 1. The majority of stomachs has one or more lesions of ulcerative process, including parakeratosis(64.1%), erosions(10.2%), acute ulcers(2.8%), chronic ulcers(1.4%), and scars(0.8%). 2. The incidence and the degree of the esophagogastric lesions in the breeding pigs were similar to those of the slaughter pigs. But ulcerative lesions of the fundic lesions in the breeding pigs were found to be more remarkable than those of the slaughter pigs. 3. The stomach contents of the pigs having gastric ulcers were mostly fluid in nature, which were dry in the normal stomach. 4. Histologically, muscular hypertrophy, connective tissue hyperplasia and vascularity were shown in the ulcerative lesions of the esophagogastric portion. Thrombosis, necrosis and granulation tissue formation were found frequently.

• Clinical Pain
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• 제20권2호
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• pp.86-92
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• 2021

Ultrasound imaging in clinical practice is one of the widely used diagnostic methods because there is no radiation risk, more cost- effective compared to MRI or CT, and possible to perform an intervention through fast real-time imaging. In order to increase the diagnostic value, the studies of contrast-enhanced ultrasound (CEUS) using an ultrasound contrast agent have been actively conducted since about 50 years ago and are being used clinically in vascularity and microcirculation of internal organs. Although ultrasound is actively used for the diagnosis and treatment of various diseases in musculoskeletal disorders, there are some limitations in diagnosing mild or small lesions, inflammatory reactions, or abnormalities at the molecular level. In this review, the principles, types, and research, and clinical applications of ultrasound contrast agents have been summarized and introduced. If we understand the characteristics of the ultrasound contrast agents and anatomical knowledge, as well as molecular changes, the ultrasound contrast agents are widely applied in musculoskeletal disorders and have tremendous potential for diagnosis and treatment.

• Clinical Endoscopy
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• 제57권2호
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• pp.164-174
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• 2024

Pancreatic cancers have a poor prognosis, and their incident rates have risen. Endoscopic ultrasonography (EUS) is an efficient and reliable diagnostic modality for pancreatic lesions, providing high spatial resolution. However, while EUS helps to detect minor pancreatic lesions, nearly all solid pancreatic lesions are hypoechoic, which creates difficulty in making differential diagnoses of pancreatic lesions. When diagnosing pancreatic lesions, the performance of image-enhanced EUS techniques is essential, such as EUS elastography or contrast-enhanced harmonic EUS (CH-EUS). CH-EUS diagnosis is based on assessing the vascularity of lesions, whereas tissue elasticity is measured via EUS elastography. Elastography is either strain or shear-wave, depending on the different mechanical properties being evaluated. The usefulness of enhanced EUS techniques is demonstrated in this review for the differential diagnosis of pancreatic lesions, including solid and cystic lesions, and pancreatic cancer staging.

• 한국의학물리학회지:의학물리
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• 제21권2호
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• pp.153-164
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• 2010

혈관분포도(vascularity) 및 세포조밀도(cellularity)와 같은 종양의 생물학적 특성을 고려한 임상표적체적을 결정하기 위하여, 국부혈류용적영상(regional cerebral blood volume map, rCBV map)과 겉보기확산계수영상(apparent diffusion coefficient map, ADC map)의 종양 체적을 해부학적 영상 위에 맵핑 할 수 있는 소프트웨어를 개발하였다. 개발한 프로그램은 해부학적 영상 및 기능 영상 간 mutual information, affine transform, non-rigid registration을 이용한 영상 정합 기능을 제공한다. 영상 정합 후 기준 영상과 정합된 영상에서 획득한 각 segmented bone의 겹치는 체적 비율 및 contour 간 평균 거리를 이용하여 정합도 평가도 가능하다. 잔여 종양이 있는 악성신경아교종 환자의 영상을 이용하여 소프트웨어의 기능을 평가하였을 때, bone segmentation과 contour 간 평균 거리 차이를 이용한 정합도는 각각 약 74%와 2.3 mm였으며, 수동정합을 이용하여 2~5% 정도의 정합도를 향상 시킬 수 있었다. 종양의 생물학적 특성을 치료 계획에 반영할 수 있도록, color map을 이용하여 rCBV map을 분석하였으며, ADC map에서 설정한 관심 영역의 평균 확산 계수와 표준 편차 등을 계산하여 종양의 예후 인자 및 악성도를 평가하였다. 두 기능 영상이 공통적으로 나타내는 종양 체적에서 얻은 생물학적 인자를 평면 위에 맵핑하여 종양의 특성을 쉽게 파악할 수 있는 multi-functional parametric map을 구성하였다. 또한 각기능 인자에 대응되는 악성 종양의 임계값을 적용하여 주변 종양 세포에 비하여 혈관 분포도는 높으면서 확산 계수는 낮아 악성 종양 세포일 확률이 높은 영역을 구분할 수 있었다. 각 기능 영상 위에서 설정한 생물학적 종양 체적 및 악성도가 높은 국소 체적은 해부학적 영상 위에 표시하여 dicom 파일로 출력할 수 있었다. 개발한 소프트웨어는 기능적 다중영상을 이용하여 생물학적 종양 체적을 해부학적 영상 위에 맵핑하는데 적용할 수 있으며, 해부학적 영상에서 파악하기 어려운 종양의 특성 변화들을 치료 계획에 활용할 수 있다. 나아가 개발한 소프트웨어를 이용하여, 한 종류의 영상을 참고하여 종양 체적을 결정했을 때 발생할 수 있는 오류를 줄이고, 치료 전이나 치료 과정에서 나타나는 종양의 조직학적, 생리학적 특성을 치료 계획에 접목하는데 활용할 수 있다.

• 대한화장품학회지
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• 제42권4호
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• pp.337-342
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• 2016

기미는 몇몇의 병인학적 요인을 갖고 있지만, 많은 연구가 멜라닌 형성에 집중되어 있다. 본 연구에서는 멜라닌 형성과 구별되는 혈관의 감소에 의한 기미의 개선을 보고자 하였다. 피부과 전문의의 육안평가를 통해 기미와 일광 흑자를 가진 한국 여성 20명을 대상으로 실험을 진행하였다. 연구 대상자는 8주 간 기능성 화장품을 사용하였다. Chromameter 기기로 측정한 연구 대상자의 기미 병변, 일광 흑자 병변 및 정상 피부 부위에서의 각 피부색 측정 결과를 분석하였다. 시료 사용 8주 경과 후, 기미 병변 부위의 피부색 밝기와 적색도가 정상 피부 부위에 비해 통계적으로 유의하게 개선되었다. 또한, 기미 병변 및 일광 흑자 병변 부위의 피부색 밝기의 개선 정도는 유사하였다. 그러나, 시료 사용 8주 경과 후 기미 병변 부위의 적색도가 일광 흑자 병변 부위에 비해 통계적으로 유의하게 개선되었다. 본 연구에서는 기능성 제품을 사용함으로써 기미 병변 부위에서 피부색 밝기 뿐만 아니라 적색도 또한 개선됨을 확인하였다. 이에 적색도가 기미 병변 부위의 평가를 위한 부가적이고 적합한 요인이 될 수 있음을 제시하고자 한다.