• Title/Summary/Keyword: Validation studies

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On Practical Choice of Smoothing Parameter in Nonparametric Classification (베이즈 리스크를 이용한 커널형 분류에서 평활모수의 선택)

  • Kim, Rae-Sang;Kang, Kee-Hoon
    • Communications for Statistical Applications and Methods
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    • v.15 no.2
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    • pp.283-292
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    • 2008
  • Smoothing parameter or bandwidth plays a key role in nonparametric classification based on kernel density estimation. We consider choosing smoothing parameter in nonparametric classification, which optimize the Bayes risk. Hall and Kang (2005) clarified the theoretical properties of smoothing parameter in terms of minimizing Bayes risk and derived the optimal order of it. Bootstrap method was used in their exploring numerical properties. We compare cross-validation and bootstrap method numerically in terms of optimal order of bandwidth. Effects on misclassification rate are also examined. We confirm that bootstrap method is superior to cross-validation in both cases.

Development of Miniaturized Automatic Chromatography System for validation Study of Chromatographic Resin lifetime (크로마토그래피 담체의 수멍을 검증하기 위한 자동화 미니 크로마토그래피 시스템 개발)

  • 박재하;서창우
    • KSBB Journal
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    • v.17 no.4
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    • pp.326-332
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    • 2002
  • The quality of biopharmaceutical proteins is strongly affected by a manufacturing process employed to produce Et, and thus validation of the manufacturing bioprocess is a very important issue. Chromatography is probably the most widely used bioprocess unit operation for protein purification. In this study, a miniaturized automatic chromatography system was designed and constructed for scale-down studies for process chromatography validation. This system, named MiniValChrom, has the following features: automatic and repeated operation, flexible sequences and intervals among the steps, on-line and real-time monitoring and control, method files savings, etc. Using the MiniValChrom, we peformed a case study of an abbreviated experiment to estimate chromatographic resin lifetime. BSA (bovine serum albumin) and Cibacron Blue 3G-A were used as the model protein and the resin, respectively. The resin deterioration was evaluated by determining and monitoring the HETP and NTP values from the chromatograms every 5 cycles. It was observed that the HETP and the NTP values were changed by 9% after 15 cycles. The resin lifetime validation could be completed by repeating this experiment until the HETP value reached a predetermined value. The MiniValChrom's concept and the protocol suggested in this study can serve as a rapid and economical tool for the validation studies of bioprocess chromatography system.

The Development of the Teaching Competency Scale for Character Education in Early Childhood Teachers (영유아교사 인성교육지도역량 척도 개발)

  • Goh, Eun Kyoung;Jeon, Hyo Jeong
    • Korean Journal of Child Studies
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    • v.37 no.5
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    • pp.129-144
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    • 2016
  • Objective: This study's purpose was to develop a teaching competency scale for character education for early childhood teachers and to examine its reliability. Methods: The study procedure was as follows: First, scale items were generated by reviewing the literature as a deductive approach and focused interviews with 8 field experts in an inductive approach. Second, face validation was assessed by 7 academic experts, and statistical validation processes were done twice. The data used in the final statistical analyses included 206 questionnaires for early childhood teachers. Statistical validation included item response analysis, item discrimination analysis, exploratory factor analysis, confirmatory factor analysis, and reliability analysis. Results: The 3 factors identified were as follows: Communicate teaching competence, practical teaching competence, and instrumental teaching competence. The validity and reliability of the Teaching Competency Scale for Character Education in Early Childhood Teachers were acceptable. Conclusion: This new scale will be a useful tool to better support character education for early childhood teachers and contribute to providing a basis for developing more sophisticated tools.

Pedestrian wind conditions at outdoor platforms in a high-rise apartment building: generic sub-configuration validation, wind comfort assessment and uncertainty issues

  • Blocken, B.;Carmeliet, J.
    • Wind and Structures
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    • v.11 no.1
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    • pp.51-70
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    • 2008
  • CFD is applied to evaluate pedestrian wind comfort at outdoor platforms in a high-rise apartment building. Model validation is focused on generic building sub-configurations that are obtained by decomposition of the actual complex building geometry. The comfort study is performed during the design stage, which allows structural design changes to be made for wind comfort improvement. Preliminary simulations are performed to determine the effect of different design modifications. A full wind comfort assessment study is conducted for the final design. Structural remedial measures for this building, aimed at reducing pressure short-circuiting, appear to be successful in bringing the discomfort probability estimates down to acceptable levels. Finally, the importance of one of the main sources of uncertainty in this type of wind comfort studies is illustrated. It is shown that the uncertainty about the terrain roughness classification can strongly influence the outcome of wind comfort studies and can lead to wrong decisions. This problem is present to the same extent in both wind tunnel and CFD wind comfort studies when applying the same particular procedure for terrain relation contributions as used in this paper.

Design of weighted federated learning framework based on local model validation

  • Kim, Jung-Jun;Kang, Jeon Seong;Chung, Hyun-Joon;Park, Byung-Hoon
    • Journal of the Korea Society of Computer and Information
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    • v.27 no.11
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    • pp.13-18
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    • 2022
  • In this paper, we proposed VW-FedAVG(Validation based Weighted FedAVG) which updates the global model by weighting according to performance verification from the models of each device participating in the training. The first method is designed to validate each local client model through validation dataset before updating the global model with a server side validation structure. The second is a client-side validation structure, which is designed in such a way that the validation data set is evenly distributed to each client and the global model is after validation. MNIST, CIFAR-10 is used, and the IID, Non-IID distribution for image classification obtained higher accuracy than previous studies.

Case Study of BIM Quality Assurance (BIM 모델의 품질검증 사례연구)

  • Jeong, Yeon-Suk;Park, Sang-Il;Lee, Sang-Ho
    • Proceedings of the Computational Structural Engineering Institute Conference
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    • 2010.04a
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    • pp.379-382
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    • 2010
  • This study proposes a way to validate BIM data quality in BIM applications. Solibri model checker is adopted as a module development platform, which is based on Java programming language. The platform makes application developers implement BIM model checker for their own purpose. This study has developed a BIM validation module for circulation analysis of building design. The validation module enables end-users to automatically detect data corrupted or not defined. In case studies, the module found that an IFC file generated from a BIM software has wrong relation information between a space and boundary elements. A building model should satisfy modeling requirements and then domain users can get analysis results. The BIM data validation module needs to be developed in each BIM application domain.

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Unsupervised learning algorithm for signal validation in emergency situations at nuclear power plants

  • Choi, Younhee;Yoon, Gyeongmin;Kim, Jonghyun
    • Nuclear Engineering and Technology
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    • v.54 no.4
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    • pp.1230-1244
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    • 2022
  • This paper proposes an algorithm for signal validation using unsupervised methods in emergency situations at nuclear power plants (NPPs) when signals are rapidly changing. The algorithm aims to determine the stuck failures of signals in real time based on a variational auto-encoder (VAE), which employs unsupervised learning, and long short-term memory (LSTM). The application of unsupervised learning enables the algorithm to detect a wide range of stuck failures, even those that are not trained. First, this paper discusses the potential failure modes of signals in NPPs and reviews previous studies conducted on signal validation. Then, an algorithm for detecting signal failures is proposed by applying LSTM and VAE. To overcome the typical problems of unsupervised learning processes, such as trainability and performance issues, several optimizations are carried out to select the inputs, determine the hyper-parameters of the network, and establish the thresholds to identify signal failures. Finally, the proposed algorithm is validated and demonstrated using a compact nuclear simulator.

Experimental studies of validation and stability of Sweet Bee Venom using HPLC (Sweet BV의 조제물 농도분석 및 안정성 확인을 위한 시험적 연구)

  • Kang, Kye-Sung;Kwon, Ki-Rok
    • Journal of Pharmacopuncture
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    • v.12 no.4
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    • pp.33-50
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    • 2009
  • Objectives : This study was conducted to confirm validation and stability of concentration analysis method of pure melittin (Sweet Bee Venom-Sweet BV) extracted from the bee venom by utilizing protein isolation method of gel filtration. Methods : All experiments were conducted at Biotoxtech, a non-clinical studies authorized institution, under the regulations of Good Laboratory Practice (GLP). Standard solutions of melittin (SIGMA, USA) and test substances were dispensed and were analyzed with HPLC for Sweet BV to secure the validation of analysis. Results : 1. Measurement of system suitability of Sweet BV satisfied criterion of below 3%. 2. Confirming Linearity of Sweet BV in 10-200${\mu}g/m\ell$ solution yielded correlation coefficient (r) of 0.995 and accuracy of 85-115% which satisfy criterion. 3. Measurement of Specificity of Sweet BV didn't yield any substance affecting the peak of test substances, but detected at 21.22min verified as the test substance. 4. Confirming Intra-day of Sweet BV, accuracy and precision of 0.1, 100${\mu}g/m\ell$ were 105.70, 95.81 and 0.66, 0.73, respectively, satisfying both criteria of accuracy (85-115%) and precision (within 10%). 5. To measure Stability in autosampler, all samples used in Intra-day reproducibility sat in the autosampler for five hours and were re-analyzed. Both variability and precision satisfied the criteria. 6. Homogeneity of Sweet BV (0.1, 100${\mu}g/m\ell$) at upper, middle, and lower layers all satisfied the accuracy and precision criteria. 7. Stability of Sweet BV (0.1, 100${\mu}g/m\ell$) at room temperature for four hours and refrigerated for 7 days all satisfied the criterion. 8. For the measurement of Quality control, QC samples measured on the first and eighth day all satisfied accuracy and precision criteria. Conclusion : Above experiment data satisfies validation and stability of concentration analysis method of Sweet BV.

Validation of QuikSCAT Wind with Resolution of 12.5 km in the Vicinity of Korean Peninsula (한반도 연안에서의 12.5 km 해상도 QuikSCAT 해상풍 검증)

  • Jeong, Jin-Yong;Shim, Jae-Seol;Lee, Dong-Kyu;Min, In-Ki;Kwon, Jae-Il
    • Ocean and Polar Research
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    • v.30 no.1
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    • pp.47-58
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    • 2008
  • Several validation studies have been made for QuikSCAT(QSCAT) wind data around the world, mainly in the offshore. However, until now, there were no validation studies for QSCAT wind with resolution of 12.5 km ('QSCAT 12.5 km wind') in the vicinity of Korean Peninsula. To validate 'QSCAT 12.5 km wind' and to investigate its characteristics around Korean Peninsula, the wind data from Ieodo Ocean Research Station, KMA buoys, and KORDI Realtime Observation Stations have been compared. Validation results showed that 'QSCAT 12.5 km wind' RMSE of wind direction and speed were $25.85^{\circ}$ and 1.83 m/s, respectively, at Ieodo Station. The mean wind speed correlation coefficient of KMA buoys and KORDI Realtime Observation Station were 0.78 and 0.61, and the mean wind speed RMSE were 2.2 m/s and 3.2 m/s, respectively. This seems to be mainly because of the distance between QSCAT and in-situ observation stations. The RMSE of wind direction were bigger than $40^{\circ}$ at all in-situ observation stations located near the shore, within 20 km from coastlines. Geophysical features where in-situ observation stations are located seem to affect wind validation scores.