• Journal of Microbiology and Biotechnology
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• v.31 no.12
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• pp.1601-1614
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• 2021

To overcome the ongoing COVID-19 pandemic, vaccination campaigns are the highest priority of majority of countries. Limited supply and worldwide disproportionate availability issues for the approved vaccines, together with concerns about rare side-effects have recently initiated the switch to heterologous vaccination, commonly known as mixing of vaccines. The COVID-19 vaccines are highly effective in the general population. However, none of the vaccines is 100% efficacious or effective, with variants posing more challenges, resulting in breakthrough cases. This review summarizes the current knowledge of immune responses to variants of concern (VOC) and breakthrough infections. Furthermore, we discuss the scope of heterologous vaccination and future strategies to tackle the COVID-19 pandemic, including fractionation of vaccine doses and alternative route of vaccination.

• Journal of Society of Preventive Korean Medicine
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• v.25 no.3
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• pp.89-99
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• 2021

Objectives : This study aimed to assess youth perception of COVID-19 vaccination in one Korean Medicine college, to compare according to COVID-19 vaccination. Method : An on-line survey using Google Form was conducted on students enrolled in one Korean medical college. Results : A total of 74 students out of 260 individuals replied, with 43 males and 31 females, 68 (91.9%) were vaccinated (or vaccine reserved), six (8.1%) were not vaccinated. The response rate was 28.5%. All the unvaccinated were intended to receive vaccines in the future. The vaccinated were most concerned about the adverse events. The unvaccinated responded that COVID-19 vaccine was unnecessary, not effective, not safe, and do not recommend vaccination to others compared to the vaccinated. Conclusion : In order to improve the COVID-19 vaccination rate, clear information on the risk of COVID-19 infection and the effects of vaccines should be known through the media.

• Asia pacific journal of information systems
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• v.32 no.1
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• pp.51-69
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• 2022

This study examines how consumers' intention to use a curbside pickup responds to the COVID-19 vaccination rates. With our first survey conducted in March 2021, we find that a low (high) vaccination rate is associated with consumers' high (low) intention to maintain contact avoidance and their high (low) anticipation for shipping delays. Heightened contact avoidance and anticipation for shipping delays may encourage consumers to use a curbside pickup. Our results also show that when a product is needed immediately, and a consumer expects shipping delays, s/he is more likely to use a curbside pickup. However, with our second survey conducted in November 2021, we find heterogeneous consumer responses to the vaccination rates. Specifically, consumers' political affiliation moderates the relationship between the vaccination rates and their intention to maintain contact avoidance. The association between the vaccination rates and the anticipation for shipping delays is also weakened compared to March 2021. Our empirical results illustrate how consumers' intention to use a curbside pickup emerges and changes amid the COVID-19 pandemic.

• Journal of the Korean Society of School Health
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• v.30 no.2
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• pp.93-102
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• 2017

Purpose: The purpose of this study is to identify the factors that influence the practices and the intentions of human papillomavirus (HPV) vaccination among adolescent daughters' mothers. The focus is on the mothers' HPV knowledge and sex-related communication with their daughters. Methods: The participants were 298 mothers with middle or high school student daughters. Participants were conveniently selected from a mothers' association and churches in Seoul, Cheonan and Asan city. Information on their demographics, HPV vaccination-related knowledge, sex-related communication, and intention of receiving HPV vaccination were obtained through questionnaires. The results were analyzed using descriptive statistics, the $x^2$ test and logistic regression with SPSS for Windows 21.0 software. Results: The rate of HPV vaccination, the awareness of the HPV vaccine and the rate of giving correct answers to HPV knowledge questions were 13.1%. 84.6%, and 36.3%, respectively. The factors that influenced HPV vaccination most were their family history of cervical cancer, educational backgrounds and awareness of the HPV vaccine. The intention to receive HPV vaccination was mainly influenced by HPV knowledge. However, sex-related communication did not affect the mothers' intention of obtaining HPV vaccination. Conclusion: The results of this study suggest that strategies to educate mothers with adolescent daughters on HPV are necessary. In addition, this study strongly recommends further studies be planned to examine sex-related communication between mothers and daughters.

• Journal of the Korea Convergence Society
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• v.8 no.11
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• pp.151-158
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• 2017

Influenza vaccination in adolescents is crucial to prevent the influenza expansion. The aim of this study was to investigate the difference of personal factors and parental factors affected influenza vaccination coverage. Study data on 12-18 years old adolescents and their parents were obtained from the 6th Korea National Health and Nutrition Examination Survey. Rao-Scott Chi-square test and multivariate logistic regression were used for the analysis. The percentage of influenza vaccination coverage in adolescents was low (26.2%). The personal factors influencing influenza vaccination were age, discomfort within two weeks, history of pneumonia, and wearing safety belt in adolescents, and the parental factors were age and influenza vaccination. In order to increase the influenza vaccination coverage for adolescents, media and healthcare professionals should provide education to adolescents and their parents about influenza vaccination.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.17
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• pp.7263-7266
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• 2014

Background: Cervical cancer which is one of the most preventable cancers is an important public health problem worldwide, and especially in developing countries. The aim of this study was to determine knowledge and attitudes about the HPV vaccination of mothers with 0- to 18-year old children. Materials and Methods: Written approval was taken from the local authorities. The study subjects consisted of 799 mothers who agreed to participate. The data were collected via a "Personal Information Form" which included 30 questions that were prepared by the researchers themselves in line with the literature. The data were collected by face to face interviews with the mothers. Analyses were performed using commercial software. Results: The mean age of the mothers who participated in the study was $32.0{\pm}6.52$, and 88.1% reported no information about HPV, and 83.5% no information about HPV vaccination. Only 0.7% of the mothers had daughters who had HPV vaccination, and 44.3% of the mothers who had sons were found out to be indecisive about having HPV vaccination. There was a significant corelation between the educational status of the mothers and their knowledge about HPV vaccination (p<0.05). However, there was no significant correlation in terms of economic conditions (p>0.05). Conclusions: This study suggested that mothers had very little information on HPV and HPV vaccination. Knowledge of the disease and its vaccination is an essential factor for the success of the vaccination program. It is of great importance that mothers are trained in this subject by health professionals.

• Journal of Digital Convergence
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• v.17 no.4
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• pp.149-157
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• 2019

This study is to evaluate the accuracy of a human papillomavirus(HVP) vaccination behavior model based on the health belief model. The subjects were 285 mothers of adolescent daughters and the data was collected from June to September, 2017. The data were analyzed using SPSS, AMOS programs. The results, perceived benefits had effects on the vaccinating behavior by completely mediating the intention while the perceived barriers had effects on the vaccinating behavior by partially mediating the intention. The vaccination intention was shown to be an important variable for predicting of vaccination behaviors while the perceived barrier was revealed to be the most influential factor for vaccination behaviors. These results could contribute to raise the understanding about HVP vaccination processes in the mothers of adolescent daughters and to develop strategies to enhance the HVP vaccination rate.

• Journal of Korean Academy of Nursing
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• v.53 no.3
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• pp.324-339
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• 2023

Purpose: This study aimed to valuate the reliability and validity of the Korean version of the 5C Psychological Antecedents of Vaccination (K-5C) scale. Methods: The English version of the 5C scale was translated into Korean, following the World Health Organization guidelines. Data were collected from 316 community-dwelling adults. Content validity was evaluated using the content validity index, while construct validity was evaluated through confirmatory factor analysis. Convergent validity was examined by assessing the correlation with vaccination attitude, and concurrent validity was evaluated by examining the association with coronavirus disease 2019 (COVID-19) vaccination status. Internal consistency and test-retest reliability were also evaluated. Results: Content validity results indicated an item-level content validity index ranging from .83 to 1, and scale-level content validity index, averaging method was .95. Confirmatory factor analysis supported the fit of the measurement model, comprising a five-factor structure with a 15-item questionnaire (RMSEA = .05, SRMR = .05, CFI = .97, TLI = .96). Convergent validity was acceptable with a significant correlation between each sub-scale of the 5C scale and vaccination attitude. In concurrent validity evaluation, confidence, constraints, and collective responsibility of the 5C scale were significant independent predictors of the current COVID-19 vaccination status. Cronbach's alpha for each subscale ranged from .78 to .88, and the intraclass correlation coefficient for each subscale ranged from .67 to .89. Conclusion: The Korean version of the 5C scale is a valid and reliable tool to assess the psychological antecedents of vaccination among Korean adults.

• Korean Journal of Veterinary Service
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• v.46 no.4
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• pp.263-268
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• 2023

Despite regular vaccinations, equine influenza virus (EIV) and Streptococcus equi subsp. equi (strangles) are the cause of highly contagious respiratory infections in horses. Many recent studies have reported that the concurrent administration of two vaccines could simplify horse management and minimize veterinary expenses. However, there is little information available regarding the efficacy of concurrent vaccinations against EIV and strangles. In this study, we evaluated EIV-specific antibody responses following the single EIV vaccination with the recombinant viral-vectored EIV vaccine or concurrent vaccination with the EIV and inactivated strangles vaccines. Blood samples were collected at 1-, 2-, 4-, and 8 weeks post-immunization (wpi) from each group. EIV-specific antibodies were evaluated by enzyme-linked immunosorbent assay (ELISA) and hemagglutination inhibition (HAI) assay. Both single and concurrent vaccination showed similar levels of EIV-specific serum immunoglobulin g (IgG) at 1 and 2 wpi. However, at 4 to 8 wpi, the EIV-only vaccination group showed significantly higher serum IgG levels than those from the concurrently vaccinated group. The HAI titers showed similar trends as the ELISA data, except at 8 wpi when both groups presented HAI titers with no significant differences. These data demonstrate that the concurrent vaccination against EIV and strangles could compromise the humoral immune response to equine influenza between vaccination intervals, which suggests the use of the consecutive vaccination protocol for EIV and strangles rather than concurrent vaccination.

• Asian Oncology Nursing
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• v.11 no.1
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• pp.65-73
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• 2011

Purpose: This study was a descriptive study to determine knowledge regarding cervical cancer, health beliefs, and Human Papillomavirus (HPV) vaccination rate of female university students. Methods: The subjects of this study were 777 female university students. The data were collected through interviews using a structured questionnaire from september 1 to October 30, 2010. The data were analysed using descriptive statistics, t-test, ANOVA, and chi-square test. Results: The mean of cervical cancer knowledge was low (13.75 score). Regarding health beliefs about HPV vaccination, the levels of perceived benefit (3.01 score) and seriousness (2.91 score) were relatively high, whereas the levels of perceived barrier (2.09 score) and susceptibility (2.01 score) were relatively low. The rate of HPV vaccination was 5.5%. Conclusion: These results show that concrete educational programs and advertisement are mandated to reduce HPV infection and increase HPV vaccination rate. Also the strategies emphasizing perceived seriousness and benefits of obtaining HPV vaccination are taken into account in developing educational programs in addition to knowledge improvement on HPV and cervical cancer.