• 한국전산유체공학회지
• /
• 제7권4호
• /
• pp.8-18
• /
• 2002

The primary objective of the present study is evaluation of the k-ε-vv-f turbulence model for prediction of natural convection in a rectangular cavity. As a comparative study, the two-layer k-ε model is also considered. Both models, with and without algebraic heat flux model, are applied to the analysis of natural convection in a rectangular cavity. The performances of turbulence models are investigated through comparison with available experimental data. The predicted results of vertical velocity component, turbulent heat fluxes, turbulent shear stress, local Nusselt number and wall shear stress are compared with experimental data. It is shown that, among the turbulence models considered in the present study, the k-ε-vv-f model with an algebraic heat flux model predicts best the vertical mean velocity and velocity fluctuation, and the inclusion of algebraic heat flux model slightly improves the accuracy of results.

• Bulletin of the Korean Chemical Society
• /
• 제7권3호
• /
• pp.241-245
• /
• 1986

The vibration-vibration energy exchange of $N_2(v=1)+O_2(v=0){\to}N_2(v=0)+O_2(v=1)$ has been investigated, in particular, at low temperatures. The energy exchange rate constants are calculated by use of the solution of the time-dependent Schrodinger equation with the interaction potential of the colliding molecule as a perturbation term. The predicted rate constants are significantly agree with a experimental values in the range of 295∼$90^{\circ}K$. The consideration of the VV-VT coupling decreases the predicted pure VV energy exchange value by a factor of ∼2. When the collision frequency correction is introduced, the VV-VT rate constant is consistent with the observed value in the liquid phase. The consideration of the population of the rotational energy level increases the VV-VT value significantly.

• 한국해양학회지:바다
• /
• 제8권3호
• /
• pp.285-294
• /
• 2003

전라북도 새만금 해역의 조하대 대형저서동물 군집의 모니터링에 적절한 채집기 선정을 위한 연구의 일환으로 2002년 4월에 현장 조사를 수행하였다. 비교 대상 채집기는 반 정량적 채집기인 dredge(type charcot)와 정량적 채집기인 Smith-McIntyre(SM), van Veen grab(VV)이었다. 11개 정점이 설정되었고, 매 정점에서 dredge는 1회, SM과 VV는 3회의 반복 채집(0.1 $m^2$$\times$3)이 이루어졌다. 채집 퇴적물의 부피와 군집 밀도, 생체량 그리고 다양도 지수등의 parameters의 비교는 정량적 채집기에 국한되었다. 퇴적물의 부피는 두 채집기 간 p-value 0.0050(쌍을 이룬 표본의 t-검정)에서 유의한 차이(SM>VV)가 있는 것으로 나타났고 자료에 4th-root변환을 가하면 SM과 Vv에 의한 3개 반복 채집 표본이 모두 정밀도 0.2의 기준을 만족하는 것으로 나타났다. 11개 정점 다양도의 채집기 간 비교에서는 dredge와 VV 간의 상관관계가 다른 pairs의 것에 비해 높은 것으로 나타났다. 우점종의 조성과 순위 비교는 일부 개체군(예를 들어 다모류, Heteromastu filiformis, Aricidea assimilis등)에서 dredge의 것이 나머지 것에 비해 과소 평가의 경향을 나타내었다. 다변량 분석 결과의 채집기 간 일치하는 정도를 추정하기 위하여 유사도 행렬 간 상관관계를 추정하였다. 근소하게 dredge와 VV 간 유사도가 높은 것으로 나타났으나 대체로 높은 일치성을 보였다. 우점종 리스트에서 관찰된 순위와 조성의 차이는 채집기마다 다른 채집 심도의 효과에 기인한 것으로 해석되었다. VV 표본에서의 일부 우점종의 낮은 밀도(SM 표본 대비 평균 50% 수준)도 이러한 관점에서 이해될 수 있었고 이것이 dredge-VV 간 상대적으로 높은 상관관계 또는 유사도의 원인인 것으로 추정되었다. 전반적인 관찰 결과에 근거하였을 때 우량 채집기는 SM이었으나 반드시 높은 자료의 질이 우선시되어야 하는 조건이 아닌 경우에는 다른 채집기를 사용하더라도 생물상의 특성 파악과 구분에는 문제가 없는 것으로 추정되었다.

• 한국산업보건학회지
• /
• 제20권3호
• /
• pp.139-146
• /
• 2010

Recent studies suggest that prolonged standing at work is associated with varicose veins (VV). The objective of this study was to analyze the differences of VV risk in terms of work types in casino dealers and hotel service workers. Symptoms of VV were evaluated using a self-reported questionnaire from 2,092 participants, and muscle fatigue in the lower legs were evaluated using surface electromyography. The shift rate of median frequency in Gastrocnemius was -30.0% among the casino dealers working in prolonged static standing posture, and - 14.3% among the casino dealers sitting during working time. After adjusting age, gender, smoking, and family history of VV, the risk ratio of VV was 3.67(95% CI 2.03-6.59) in group I (prolonged standing and occasional walking at work), 6.29(95% CI 3.48-11.35) in group II (prolonged standing, occasional walking and heavy lifting at work), and 8.07(95% CI 4.51-14.43) in groupIII(prolonged static standing at work). In conclusion, prolonged standing at work may be a work related risk factor of VV.

• 대한수의학회지
• /
• 제29권3호
• /
• pp.407-416
• /
• 1989

The prospect of live vaccines consisting of genetically modified vaccinia virus expressing foreign genes is exciting, but important issues concerning safety and efficacy need to resolved. Vaccinia virus (VV) is an efficient expression vector with broad host range infectivity and large DNA capacity. This vector has been particularly useful for identifying target antigens for humoral and cell-mediated immunity. The WHO smallpox eradication program, involving the extensive use of VV vaccines, resulted in the late 1970s in the elimination of one of the world's most feared diseases. This achievement is a triumph for preventive medicine and for international collaboration in public health. In 1980, WHO recommended that the routine use of smallpox vaccine should be stopped. Against this background, the prospect of li ve vaccines consisting of genetically modified VV expressing foreign antigens arising from the work of Moss, and Paoletti and their colleagues in 1982 has been greeted with enthusiasm. These investigators have shown that genes coding for immunogenic proteins can be inserted into VV DNA without impairing the ability of the virus to grow in cell culture. Moreover experimental animals infected with VV recombinants containing genes coding for a variety of immunizing proteins have been shown to be protected against challenge infection with the corresponding infectious agent. In this communication, I describe current progress in the construction of a novel plasmid vector that facilitate the insertion and expression of foreign genes in VV as well as the selection of recombinants.

• 한국시뮬레이션학회논문지
• /
• 제19권4호
• /
• pp.189-198
• /
• 2010

임무공간개념모델(CMMS, Conceptual Model of the Mission Spaces)은 실 군사 세계의 임무 수행과 관련한 전투요소 객체와 행위, 객체간의 상호 작용을 개념적 차원에서 나타낸 지식(임무영역) 참조모델로, 국방 M&S 시스템의 개발 및 상호 운용성, 재사용성을 제고시키는데 있어 기본이 되는 모델이다. CMMS의 완전성은 이에 기반을 둔 모든 M&S 체계의 품질을 보장함에 있어 중요한 요소인데, 이의 완성도를 높이기 위한 검증, 확인 및 인정(VV&A, Verification, Validation and Accreditation)과정은 매우 중요하다. 본 연구에서는 현재 국내에서 연구 진행 중인 한국형 CMMS에 대하여 소개하고 CMMS의 개발 및 관리시스템의 신뢰성을 보장할 수 있는 CMMS VV&A 적용 방법을 제안하고자 한다.

• 대한전자공학회논문지
• /
• 제25권8호
• /
• pp.966-971
• /
• 1988

AES was used to study oxygen adsorption due to the oxygen exposure at 300\ulcorner temperature and segregation of impurities due to annealing on polycrystal copper surface. The intensity of peak of CuM2, 3VV and CuL3 VV increased with annealing time and the peak of CKLL increased after Ar ion bombardment. The effect of oxygen adsorption on copper surface at 300\ulcorner was verified by the decreased of peak of CuM2, 3VV and CuL3 VV as oxygen exposure increase. The binding energy of copper atoms gradualy shifts from 0.7eV to 1.5eV of copper atoms gradually shifts from 0.7eV to 1.5eV after a oxygen exposure. After the oxygen exposure, the width at half the height of CuM2, 3VV is larger 2V*C/S by the effect of chemical liaison of the copper aton with oxygen atom.

• 대한미생물학회지
• /
• 제35권3호
• /
• pp.251-261
• /
• 2000

V. vulnificus is an estuarine bacterium which causes septicemia and shock in susceptible patients. The organism produces a hemolytic cytolysin (VvH), which has a membrane damaging effect on erythrocytes. To clarify the mechanisms by which VvH might contribute to virulence, we examined its effect on macrophages. When mouse peritoneal macrophages were harvested and co-cultured with hemolysin-positive V. vulnificus strains (100 bacteria/cell), about 60% of the macrophages were killed; macrophages were not killed when co-cultured V. vulnificus strain CVD 707, a VvH-negative deletion mutant. Exposure of macrophages to filtered culture supernatants (2.5 HU/ml) and purified VvH (3 HU/ml) resulted in an increase in dead cells (80 and 90%, respectively), as determined by the trypan blue dye exclusion method and LDH release from macrophages was also increased (70 and 65.5%, respectively). The cytotoxic effect of VvH on macrophages was both the dose- and time-dependent. The VvH caused damage to the macrophage membrane and was blocked significantly by preincubation with cholesterol (p<0.01). Fetal bovine serum showed remarkable inhibition of VvH synthesis by V. vulnificus and inhibited VvH activity in culture supernatant. Cell viability was increased by 35% (p<0.01) and LDH release decreased by 28% (p<0.01) when macrophages were incubated with V. vulnificus (100 bacterial cell) in DMEM-10% FBS for 2 hr. Bacterial clearance activity of mice against V. vulnificus CVD 707 was decreased by pretreatment with 10 HU of VvH. This result suggests that the VvH can impair the membrane of macrophages and may playa role in the pathogenesis of V. vulnificus septicemia.

• Asian-Australasian Journal of Animal Sciences
• /
• 제9권6호
• /
• pp.679-684
• /
• 1996

This study evaluates the susceptibility of scaleless mutant chickens to very virulent Marek's disease virus (vvMDV) inoculation. One day old chickens were inoculated subcutaneously with Taiwanese isolates of LTB-1 and LTS-1 strains, and standard strain of Md/5. Compared with the non-inoculated group the vvMDV-inoculated chickens showed decreased body weights and atrophy of lymphoid organs before 35 days old. These results indicate that scaleless chickens show the same susceptibility as the wild type chickens to vvMDV infection. Furthermore, the protective effect of herpesvirus of turkey (HVT) vaccination at 1 day old against vvMDV challenge was evaluated. Scaleless mutant chickens of treated groups showed 20-30% early death, and 85.7-100% and 12.5-14.2% had lymphomatous lesions in visceral organs and peripheral nerves, respectively. No significant lesions were observed in non-challenged chickens of the control group. The HVT vaccination did not provide an effective protection against vvMDV infection. It is concluded that scaleless mutant chickens are susceptible to vvMDV infection.

• 한국시뮬레이션학회:학술대회논문집
• /
• 한국시뮬레이션학회 2001년도 The Seoul International Simulation Conference
• /
• pp.391-395
• /
• 2001

Model verification, validation and accreditation (VV&A) of system simulation are detailedly discussed in this paper. The necessity of VV&A is explained by analyzing the factors on which the model and the reality are discrepant. The W&A technology is expounded in detail not only in the conceptual aspect but also in the methodological aspect. Some principles, difficulties and problems that should be paid attention to are discussed concretely and reasonedly. The paper is expected to be instructional and helpful to the VV&A study.