• Korean Journal of Plant Resources
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• v.29 no.3
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• pp.297-304
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• 2016

The seed of safflower (Carthamus tinctorius L) has been reported to suppress human cancer cell proliferation. However, the mechanisms by which safflower seed inhibits cancer cell proliferation have remained nuclear. In this study, the inhibitory effect of the safflower seed (SS) on the proliferation of human colorectal cancer cells and the potential mechanism of action were examined. SS inhibited markedly the proliferation of human colorectal cancer cells (HCT116, SW480, LoVo and HT-29). In addition, SS suppressed the proliferation of human breast cancer cells (MDA-MB-231 and MCF-7). SS treatment decreased cyclin D1 protein level in human colorectal cancer cells and breast cancer cells. But, SS-mediated downregulated mRNA level of cyclin D1 was not observed. Inhibition of proteasomal degradation by MG132 attenuated cyclin D1 downregulation by SS and the half-life of cyclin D1 was decreased in SS-treated cells. In addition, SS increased cyclin D1 phosphorylation at threonine-286 and a point mutation of threonine-286 to alanine attenuated SS-mediated cyclin D1 degradation. Inhibition of ERK1/2 by PD98059 suppressed cyclin D1 phosphorylation and downregulation of cyclin D1 by SS. In conclusion, SS has anti-proliferative activity by inducing cyclin D1 proteasomal degradation through ERK1/2-dependent threonine-286 phosphorylation of cyclin D1. These findings suggest that possibly its extract could be used for treating colorectal cancer.

• Journal of IKEEE
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• v.16 no.4
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• pp.395-404
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• 2012

In this paper, the perceived loudness metering algorithm based on ITU-R BS.1387-1 was investigated and implemented, and its performance was evaluated by applying to 23 pure tones and 9 digital audio samples. Error of the tone test results compared with ISO226:2003 was below 5%, and sample test results, in comparison with Moore's algorithm, showed deviation of less than 4.7% and correlation of 0.96. On the other hand, it was investigated how the implemented algorithm's performance was subject to auditory pitch scale. Its result showed that the algorithm with 37 auditory filters, through correcting a bias effect, has a good performance of less than 2% in comparison with the one with 109 auditory filters.

• Clean Technology
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• v.22 no.4
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• pp.250-257
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• 2016

As an attempt to replacing petroleum-based chemicals with bio-based ones, synthesis of furfural from biomass-derived xylose attracts much attention in recent days. Conventionally, furfural from xylose has been produced via the utilization of highly corrosive, toxic, and environmentally unfriendly mineral acids such as sulfuric acid or hydrochloric acid. In this study, microwave-assisted biphasic reaction process in the presence of novel bio-based heterogeneous acid catalysts was developed for the eco-benign and effective synthesis of furfural from xylose. The microwave was irradiated for reaction acceleration and a biphasic system consisting of $H_2O$ : MIBK (1 : 2) was designed for continuous extraction of furfural into the organic phase in order to reduce the undesired side products formed by decomposition/condensation/oligomerization in the acidic aqueous phase. Moreover, sulfonated amorphous carbonaceous materials were prepared from wood powder, the most abundant lignocellulosic biomass. The prepared catalysts were characterized by FT-IR, XPS, BET, elemental analysis and they were used as bio-based heterogeneous acid catalysts for the dehydration of xylose into furfural more effectively. For further optimization, the effect of temperature, reaction time, water/organic solvent ratio, and substrate/catalyst ratio on the xylose conversion and furfural yield were investigated and 100% conversion of xylose and 74% yield of furfural was achieved within 5 h at $180^{\circ}C$. The bio-based heterogeneous acid catalysts could be used three times without any significant loss of activity. This greener protocol provides highly selective conversion of xylose to furfural as well as facile isolation of product and bio-based heterogeneous acid catalysts can alternate the environmentally-burdened mineral acids.

• Journal of the Korean Society of Food Science and Nutrition
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• v.24 no.6
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• pp.970-977
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• 1995

Effect of garlic intake on the antifatigue and fatigue recovery during prolonged exercise have been investigated. 16 male college students(8 persons of control group and the same numbers of garlic intake group), aged from 20 to 22 years, were subjected to the restricted experiment and maintained their same menu with exercise in life pattern during 14 days of program. In garlic intake group, 30g of garlic was given with every 3 meal per day to each person. A significant increase in HDL-cholesterol level was shown in the garlic intake group while total cholesterol, LDL-cholesterol and lactate level decreased by garlic intake. Lactate dehydrogenase activity in serum increased by garlic intake, however garlic intake was not significantly affected on Vo2, Vco2, ventilation, respiratory quotient. In conclusion, garlic intake seemed to be effective for antifatigue and tatigue recovery during prolonged exercise.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2011.10a
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• pp.237-240
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• 2011

Voice over Internet Protocol calls using administrative agency to build a national information and communication service, 'C' group, providers, the KT, SK Broadband, LG U+, Samsung SDS, as there are four operators. To prepare for an attack on Voice over Internet Protocol for administrative agency, security is a need for research to support the model. In this paper, the Internet telephone business of Administrative Agency to investigate and analyze the specific security measures to respond. Should set priorities around confidentiality about five security threats from NIS to Study of Voice over Internet Protocol Security Response Model for Administrative Agency. (1) Illegal wiretapping, (2) call interception, (3) service misuse, (4) denial of service attacks, (5) spam attacks, write about and analyze attack scenarios. In this paper, an analysis of protection by security threats and security breaches through a step-by-step system to address the research study is a step-by-step development of the corresponding model.

• Environmental Engineering Research
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• v.19 no.3
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• pp.229-240
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• 2014

Rain events are extremely important for phosphorus (P) dynamics in rivers since large portions of annual river P loads can be transported in particulate forms during only a few major events. Despite their importance, a precise estimation of P contribution in river sediments after rainy seasons has rarely been reported. This study estimated the longitudinal variation in the concentrations of different inorganic P fractions in bed sediments of the South Han River over a rainy season, through using the sequential extraction method. Non-apatite P was the dominant form, representing more than 60% of total inorganic P (TIP) content in sediments. Although no significant variation of TIP contents was observed, the proportion of bioavailable P in TIP pools decreased after the rainy season. The concentrations of individual inorganic P fractions ($NH_4Cl-P$, $NH_4F-P$, NaOH-P, and $H_2SO_4-P$) were significantly different across sites and after the rainy season (p < 0.05, two-way ANOVA). $NH_4F-P$ and NaOH-P concentrations in sediments increased in a downstream direction. After the rainy season, $NH_4Cl-P$ concentrations in sediments decreased whereas $NH_4F-P$ and $H_2SO_4-P$ concentrations increased. The redistribution of individual P fractions in sediments observed after rainy seasons were possibly due to the changing contribution of various sources of runoff and the variation in flow related particle size. Current estimation of P in bed sediments of the South Han River suggests a lower potential of internal P loading from sediments after the rainy season.

• Fisheries and Aquatic Sciences
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• v.26 no.8
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• pp.470-481
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• 2023

Algal overgrowth in shrimp culture ponds can affect the quality of the aquatic environment, thereby adversely affecting the shrimp and causing economic losses. The objective of this study was to evaluate the variation in phytoplankton composition in intensive shrimp ponds in Bac Lieu province, Vietnam. Phytoplankton samples were collected in three black tiger shrimp (Penaeus monodon) ponds and three whiteleg shrimp (Litopenaeus vannamei) ponds. The collected data were analyzed using SPSS and canonical correlation analysis softwares. In total, 75 species of phytoplankton were recorded in black tiger shrimp ponds and 64 species in whiteleg shrimp ponds. Diatoms had the highest species diversity with 29-30 species (39%-47%), followed by green algae with 9-19 species (14%-25%); species numbers of other phyla varied from 5-12 (8%-16%). The total number of phytoplankton species throughout the study varied from 34-50 species. Algal density was relatively high and ranged from 497,091-2,229,500 ind./L and 1,301,134-2,237,758 ind./L in black tiger shrimp and whiteleg shrimp ponds, respectively. The diatom density tended to increase during the final stage of the production cycle in black tiger shrimp ponds. Blue-green algae and dinoflagellates also increased in abundance at the end of the cycle, which can affect shrimp growth. Diatoms were significantly positively correlated with pH, salinity, total ammonia nitrogen, and nitrate (NO₃^-) concentrations (p < 0.05). Blue-green algae and dinoflagellates were positively correlated with salinity, phosphate (PO₄^3-), and NO₃^-. Algal species diversity was lower in the whiteleg shrimp ponds than in the black tiger shrimp ponds. Several dominant algal genera were recorded in the shrimp ponds, including Nannochloropsis, Gyrosigma, Chaetoceros, Alexandrium, and Microcystis. The results of this study provide basic data for further investigations, and they contribute to the management of algae in brackish-water shrimp ponds.

• Journal of Korean Society of Forest Science
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• v.106 no.3
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• pp.288-299
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• 2017

This study was conducted to find out the influence of drought stress on physiological responses of Synurus deltoides. Drought stress was induced by withholding water for 25 days. Leaf water potentials were decreased of both predawn (${\Psi}_{pd}$) and mid-day (${\Psi}_{mid}$) with increasing drought stress, but water saturation dificit (WSD) was 7 times increased. ${\Psi}_{pd}-{\Psi}_{mid}$ showed the significant difference of 0.22~0.18 MPa in stressed before 10 days, and nonsignificant as treatment time became longer. A strong reduction of stomatal conductance ($gH_2O$) and stomatal transpiration rate (E) were observed after 15 days of drought stress Significant reductions of net apparent quantum yield (${\Phi}$) and maximum photosynthesis rate ($Pn_{max}$) were observed after 20 days of drought stress; However, water use efficiency (WUE) was shown the opposite trend. This implies that decrease of photosynthesis rate may be due to an inability to regulate water and $CO_2$ exchanged through the stomata. From JIP analysis, flux ratios (${\Psi}_O$ and ${\Phi}_{EO}$) and performance index on absorption basis ($PI_{ABS}$) were dramatically decreased withholding water after 15 days, which reflects the relative reduction of photosystem II activity. The leaf of S. deltoides showed osmotic adjustment of -0.35 MPa at full turgor and -0.40 MPa at zero turgor, and also cell-wall elastic adjustment of 9.4 MPa, indicating that S. deltoides tolerate drought stress through osmotic adjustment and cell-wall elastic adjustment. The degree of change in water relations parameters such as Vo/DW, Vt/DW decreased with increasing drought stress. This result showed that S. deltoides was exhibited a strong reduction of photosynthetic activity to approximately -0.93 MPa of predawn leaf water potential, and both of osmotic adjustment and cell-wall elastic adjustment in drought stress condition appears to be an important adaptation for restoration in this species.

• The Korean Journal of Physiology
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• v.27 no.2
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• pp.209-215
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• 1993

The aim of the present study was to derive regression equations for $\dot{V}o_{2max}\;vs.\;\dot{V}o_{2peak},\;and\;\dot{V}o_2\;vs.$ heart rate, exercise time, and other variables from maximal exercise tests on a treadmill using the Bruce and inclined protocols. Twelve male and 10 female Korean college students aged between 19 and 23 years voIunteered for this study. After the resting measurements, the subjects performed a maximal exercise on a treadmill according to the Bruce protocol. When the resting conditions were restored, the subjects performed another maximal exercise according to an inclined protocol where the speed was fixed at 8.05 $km{\cdot}h^{-1}$ and the grade was incremented starting from 09t by 2.5% for every 2 min. Peak $\dot{V}o_2$ observed during the Bruce exercise $(\dot{V}o_{2peak})$ was $37.7{\pm}2.4\;and\;31.7{\pm}1.8\;ml\;kg^{-1}\;min^{-1}$ in the male and female groups, respectively. Peak $\dot{V}o_2$ observed during the inclined exercise was higher than $\dot{V}o_{2peak}$ during the Bruce exercise. Maximum $\dot{V}o_2$ value observed during the tyro exercises $(\dot{V}o_{2max})$ was $43.0{\pm}2.8\;and\;36.2{\pm}1.4\;ml\;kg^{-1}\;min^{-1}$ in the male and female groups, respectively. Thus, $\dot{V}o_{2peak}$ by the Bruce protocol was about 12% (male) or 13% (female) lower than $\dot{V}o_{2max}$, and a linear relationship was found between $\dot{V}o_{2peak}$ and $\dot{V}o_{2max}$. The peak values of % $\dot{V}o_{max}$ with the Bruce protocol were $89.2{\pm}3.3\;and\;87.5{\pm}3.6%$ and those with the inclined protocol $97.7{\pm}1.8\;and\;96.9{\pm}2.0%$ in the male and female groups, respectively. In the female group, $%\dot{V}o_{2max}$ at a given workload was higher than in the male group, while $\dot{V}o_{2}$ per kg body weight was the same. Maximum HR observed during the two exercises was $204{\pm}2\;and\;195{\pm}3\;beat\;min^{-1}$ in the male and female groups, respectively. Linear relationships were found, excluding the last points, between 1) $\dot{V}o_{2}$ and exercise time, 2) $\dot{V}o_{2}$ and $%\dot{V}o_{2max}\;and\;%HR_{max}$.

• Korean Journal of Plant Resources
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• v.24 no.4
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• pp.413-418
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• 2011

This study was carried out to establish a proper cultivation site and diagnose the drought-tolerance of Aster scaber and Synurus deltoides leaves by using Pressure-volume curves. In order to measure pressure-volume (P-V) curves, Aster scaber and Synurus deltoides were cut off above ground part and the tip of the cutting were placed in water, which was covered with a plastic bag. Samples were kept overnight (about 12 hours) in darkness at room temperature (20~25$^{\circ}C$) to achieve maximal turgor (full saturation). The pressure in the chamber was gradually increased from 0.3MPa to 1.8MPa by nitrogen gas. After measured, leaf samples were dried at 80$^{\circ}C$ for 48 hours and dry weight of each samples were determined. The result of the original bulk osmotic potential at maximum turgor ${\Psi}^{sat}_o$ sat was lower -0.8 MPa in Aster scaber leaves than -0.7 MPa Synurus deltoides leaves. Also the osmotic potential at incipient plasmolysis ${\Psi}^{tlp}_o$ in Aster scaber leave was -0.9 MPa. In contrast, the value of maximum bulk modulus of elasticity $E_{max}$ of Aster scaber leaves were approximately two folds higher than that of Synurus deltoides leaves. The values of the relative water content at incipient plasmolysis $RWC^{tlp}$ are all above 90% showing that the function of osmoregulation is somewhat better, and Vo/DW, Vt/DW, Ns/DW of Synurus deltoides leaves were approximately 1~2 times higher than that of Aster scaber leaves. Thus, responses to water relations of Aster scaber and Synurus deltoides such as ${\Psi}^{sat}_o$, ${\Psi}^{tlp}_o$, $E_{max}$, ${\Psi}_{P,max}$, $RWC^{tl}$ were shown that the Aster scaber leaves was slightly higher drought-tolerance than Synurus deltoides leaves. However, in both of Aster scaber and Synurus deltoides, occurring incipient plasmolysis at the high water content, have a relatively lower drought-tolerance property indicating that growth of these plants are cultivated appropriate in high moisture soil sites.